GIMM – Gulbenkian Institute for Molecular Medicine

Too much of a good thing: Researchers at GIMM uncover a molecular brake that keeps muscle architecture in check

A molecular brake in muscle architecture prevents T-tubule growth, maintaining muscle fibre coordination. The cortical actin network restricts membrane availability, allowing for controlled T-tubule formation.

SourceGIMM – Gulbenkian Institute for Molecular Medicine·JournalScience Advances·TypeExperimental study·DateSep 2, 2026

GIMM uncovers flaws in lab-grown heart cells and paves the way for improved treatments

Researchers at GIMM discovered lab-grown heart cells are stuck in an immature stage, failing to replicate human heart characteristics. A new reference map provides a benchmark for assessing cell development, enabling more accurate disease models and effective treatments.

SourceGIMM – Gulbenkian Institute for Molecular Medicine·JournalStem Cell Reports·TypeExperimental study·DateJan 6, 2026