African-led initiative calls for increased research and advocacy on rectal microbicides to address the growing issue of unprotected anal intercourse in Africa, which is 10-20 times more likely to result in HIV infection than unprotected vaginal intercourse.
A multinational trial found that taking an antiretroviral tablet daily can prevent HIV in gay men, with a 43.8% reduction in new infections compared to a placebo. Regular adherence and monitoring are crucial for this strategy to work.
The world's third rectal microbicide trial has been launched in Pittsburgh, Pennsylvania, to test the safety and acceptability of tenofovir gel. The study aims to determine if rectal use of the gel reduces the risk of HIV among men and women who engage in receptive anal intercourse.
A vaginal gel containing 1% tenofovir has been shown to significantly reduce a woman's risk of HIV infection and genital herpes. The study found that the gel was 39% effective in reducing HIV risk during vaginal intercourse, increasing to 54% for women using the gel in over 80% of their sex acts.
New research from the Microbicide Trials Network indicates that some lubricants have toxic effects on cells and rectal tissue. The study's findings support IRMA's calls for safer lubricant options, emphasizing the importance of condom use with compatible lubricants to prevent HIV transmission.
International Rectal Microbicide Advocates releases a comprehensive report outlining the growing field of rectal microbicide R&D, highlighting optimism among researchers and advocates. The organization calls for increased funding and diversity in the funding portfolio to support safe and effective rectal-specific products.