A study has found that human chorionic gonadotropin (hCG) reduces HIV viral protein production and protects against skin lesions in transgenic mice. The hormone may also explain the low rate of mother-to-infant HIV transmission, and has potential for treating wasting syndrome in children and adults.
Researchers have successfully used gene therapy to trigger saliva production in rats with damaged salivary glands, a condition similar to that experienced by head and neck cancer patients. The treatment involves infecting ductal cells with an adenovirus carrying the aquaporin gene, which allows them to produce fluid and secrete saliva.
Scientists have discovered a new gene that causes Rieger syndrome, a rare disorder affecting tooth development and leading to glaucoma in 50% of cases. The RGS gene is similar in structure to genes found in fruit flies and mice, suggesting its role in human development.
An international team of scientists has identified the gene responsible for anhidrotic ectodermal dysplasia (EDA), a condition affecting the development of skin, hair, and teeth. The discovery provides a molecular marker to identify female carriers and is a step towards developing therapeutic interventions.