A recent study found that minocycline, an antibiotic with anti-inflammatory properties, significantly improved depressive symptoms in patients with treatment-resistant depression and low-grade peripheral inflammation. The trial showed that patients with higher C-reactive protein levels responded better to minocycline treatment.
A large international study evaluated the UK National Early Warning Risk Score 2 for predicting severe COVID-19 outcomes. The scoring system, widely used in UK NHS trusts, showed moderate success in short-term predictions but poor-to-moderate accuracy in medium-term outcomes.
Researchers found that teenagers diagnosed with depression show a significant decline in educational attainment, especially in GCSEs. Targeted support for children struggling with depression could benefit vulnerable groups, such as boys and those from disadvantaged backgrounds.
Adding CBT to standard medical care gives patients with dissociative seizures longer periods of seizure freedom and a greater quality of life. This study suggests that CBT combined with specialist care can improve symptoms and satisfaction for those affected by this condition.
A comprehensive meta-analysis of pre- and perinatal risk factors for psychosis has identified 30 significant risks and five protective factors. Researchers found that nutritional deficiencies, low birthweight, and lack of prenatal care visits pose a risk to children developing psychosis.