Peter Vitiello receives NIH grant to investigate oxygen-sensitive molecules influencing lung growth in premature infants. The research aims to reduce the burden of lasting lung disease, which can have life-long effects.
A 9-day-old baby who suffered a normally fatal stroke was saved after Dr. Alexander Drofa removed the clot by combining mechanical and medicinal therapies. The infant's coma made the case particularly challenging.
A recent study by Sanford Health identified gene mutations that could impact treatment for adult cancer patients. The study found nearly 90% of patients had genes that matched treatment options, with 40% able to receive personalized therapy.
Researchers have developed a new treatment that blocks neurotransmitters to prevent nausea and vomiting caused by chemotherapy, significantly improving patient outcomes. The study found that 74% of participants experienced no nausea or vomiting when treated with olanzapine, compared to 45% on placebo.
Researchers from Sanford Research successfully modeled Smith-Lemli-Opitz syndrome using induced pluripotent stem cells, highlighting the role of Wnt/β-catenin defects in cholesterol synthesis. The study provides new insights into the underlying cellular mechanisms of this rare developmental disorder.
Researchers at Sanford Research have created an animal model to study choroid plexus carcinoma, a pediatric brain tumor. The study identified a new genetic pathway and targeted the Sonic Hedgehog protein as a potential treatment.