Researchers developed two innovative methods for intracellular polymerization using light stimuli, offering precise spatial and temporal control. These methods have the potential to modulate various cellular functions, making them a promising avenue for therapeutic interventions.
Researchers at Shenzhen Institute of Advanced Technology developed a novel approach to create degradable living plastics by programming spores to secrete enzymes that break down plastic. The 'living plastics' degrade efficiently within 6-7 days, outperforming regular plastics even with surface damage.
A research team developed an unsupervised domain adaptation approach called DDSP, achieving high-precision cross-modality segmentation without target modality labels. The framework diverges from GANs and incorporates inter-channel similarity feature alignment to boost flexibility and precision.
A study by SIAT researchers found that microplastic exposure can cause intestinal damage, disrupt sleep patterns, reduce ovary size, and shorten lifespan in fruit flies. The research also revealed genotoxic effects on metabolic processes in the brain and ovary, emphasizing the urgent need to address environmental microplastic pollution.
A new Diffusion-based Graph Contrastive Learning (DGCL) method constructs brain networks with unique features, capturing key connections and eliminating redundant ones. DGCL outperforms existing tools in terms of efficiency and prediction accuracy for brain disease analysis.
Researchers proposed a design strategy to mitigate nonlinear responses in polycrystalline metal halide perovskite X-ray detectors, addressing issues like 'delay' and 'ghosting'. The study demonstrated high-resolution X-ray imaging with suppressed ghosting contrast and top sensitivity for similar X-ray energies among polycrystalline per...
A new procedure has been developed to isolate and culture primary mouse hepatocytes in a 2D environment, using holographic acoustic tweezers. The method allows for significant amplification of liver cell functions and the formation of liver-like structures.
Research reveals that neurons expressing estrogen receptor 1 (LS Esr1) in the lateral septum are crucial for reward-seeking and methamphetamine addiction. Targeting these neurons and HCN1 channels may be a promising strategy for treating drug addiction.
Researchers discovered that inhibiting estrogen receptor alpha in adipocytes can rescue bone loss and promote osteogenesis. This approach has potential as a therapeutic target for treating osteoporosis and preventing bone loss.
A new 3D printing strategy enables creation of complex gradient pore structures, enhancing processing capabilities for biomimetic manufacturing and bioprinting. The approach allows for precise control over filament diameter, enabling the fabrication of 1D, 2D, and 3D gradient structures.
The researchers successfully transformed brittle semiconductors into flexible fibers, enabling innovative applications in flexible electronics. The fibers have broad application prospects in wearables, the metaverse, AI, extreme environment sensors, and brain-computer interfaces.
Researchers at Shenzhen Institute of Advanced Technology (SIAT) have developed a novel acoustothermal transfection device to enhance the permeability of cell and nuclear membranes. The study found that the method achieved efficient cargo delivery into hard-to-transfect cells with high efficiency.
Chinese researchers have developed a high-performance perovskite X-ray detector that offers improved spatial resolution, readout speed, and low-dose detection efficiency for medical imaging applications. The new detector uses a thick inorganic CsPbBr3 perovskite film printed on a dedicated CMOS pixel array.