A new study finds that prostate-specific antigen (PSA) is clinically unreliable for diagnosing prostate cancer, with low levels not meaningfully related to the disease. Prostate cancer is being over-diagnosed and over-treated due to a misconception about PSA's role in the disease.
Researchers found that cystamine treatment alleviated tremors and prolonged lifespan in mice with neurological disorder mimicking Huntington's. The study suggests a similar treatment strategy may be effective in humans, highlighting the potential for neuroprotective proteins to counteract the disease.
Researchers at Stanford Medicine developed a system to study genetics and evolution in natural populations using the three-spine stickleback fish. They found parallels between laboratory genetics and evolutionary changes in the fish, suggesting that evolution can occur through large-effect gene changes.
A team of researchers at Stanford Medicine has discovered a new gene family, the Tim family, that plays a crucial role in asthma development. The link between this gene family and the hepatitis A virus may help explain why asthma rates have increased where hepatitis A infection rates have dropped.
A study by Stanford University urologist James D. Brooks confirms a direct connection between selenium and reduced risk of prostate cancer, particularly among older men with lower blood levels of the essential mineral.
A 1998 study on childhood sexual abuse has been widely discredited by Stanford researchers, citing flawed research methods and misleading data. The authors re-examined the data and found significant problems with the initial analysis, including biased samples and misreporting of original data.
Researchers at Stanford and UCSF have identified osteopontin as a key gene in the progression of multiple sclerosis, with findings suggesting its expression levels are related to disease severity. The study also revealed that osteopontin-deficient mice experienced significantly less severe symptoms and higher remission rates.
A new Stanford University study analyzed the costs and benefits of two treatments: implantable cardioverter defibrillators (ICDs) and the drug amiodarone. ICDs were found to be the most effective in preventing sudden cardiac death, but also came with the highest costs. Amiodarone produced intermediate benefits and costs.
Researchers identified three genetic subtypes of lung adenocarcinomas, each associated with different survival rates and treatment outcomes. The study could improve diagnosis and treatment options for patients with this aggressive form of lung cancer.
Researchers at Stanford Human Genome Center developed a powerful new computer program called Mapper to map thousands of genetic markers simultaneously. This allows for high-resolution maps with better local area resolution and rapid rebuilding process.
Stanford researchers are working on a new PSA test that can distinguish between cancerous and non-cancerous prostate enlargement. By analyzing the PSA protein extracted from enlarged prostates, they aim to eliminate unnecessary biopsies. The team's approach has shown promising results, reducing false positives by up to 86%.