Immunology researchers from The University of Queensland have identified UMAP as a powerful tool for analyzing large patient datasets. This method performed significantly better than PCA in reducing the complexity of big data, enabling accurate patient stratification and clustering. The findings could lead to the adoption of targeted t...
The new T3 Cleanrooms facility at the Translational Research Institute is accelerating Australian medical innovations into clinical trials. The facility provides small-scale sterile product manufacturing and training capacity for researchers, start-ups, and companies.
A large-scale clinical trial has shown that lanthanum carbonate does not reduce the risk of cardiovascular disease developing in patients with chronic kidney disease. High phosphate levels are a common problem in kidney disease and linked to cardiovascular disease, but the study found no benefit from the medication.
The new vaccine targets key tumour cells, maximising effectiveness while minimising side effects. It can be produced as an 'off the shelf' clinical grade formulation, addressing financial and logistical issues.
A large clinical trial, CKD-FIX, found that allopurinol does not prevent worsening of kidney disease. The study showed no difference in kidney function decline between the treatment and placebo groups.
Researchers have discovered a new approach to overcome chemotherapy resistance in clear cell ovarian cancer by using low doses of 2-deoxy-D-glucose. The treatment has shown significant improvement in laboratory models and is expected to be safer for patients with reduced side effects.