Articles tagged with Biotechnology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have discovered that endophytic bacteria can coexist with plant cells without harming them, triggering the production of previously unattainable compounds. This method has the potential to expand the diversity of obtainable plant-derived compounds for various industries.
Lipid droplets regulate diverse cellular processes in cancer, including membrane biosynthesis and metabolic homeostasis. Targeting lipid metabolism may disrupt tumor survival and counteract immune cell-mediated protumorigenic effects.
Researchers created a 3D chip platform called ASTEROIDS that mimics human physiology and enables precise testing of new drugs and personalized medicine models. The technology has the potential to reduce animal testing in cancer research and improve human clinical outcomes.
Researchers at Sultan Qaboos University successfully demonstrated large-scale spirulina production under local conditions, reducing reliance on imported nutritional products. The project opens opportunities for industry collaboration and contributes to national goals of sustainability, food resilience and economic diversification.
Researchers have developed a flexible, hair-like device that tracks vital signs of a fetus in real-time during surgery. This innovation provides continuous monitoring without invasive access, enabling faster interventions to prevent complications.
The American Association for the Advancement of Science (AAAS) has partnered with Research Networks to publish Computational and Structural Biotechnology Journal, Computational and Structural Biotechnology Reports, and Brain Organoid & Systems Neuroscience Journal as Science Partner Journals. These journals will publish high-quality re...
A new theory of proprioception challenges traditional understanding by incorporating frontier bionic evidence. The proposed framework reconceptualizes proprioception as a dynamic augmentable interface, enabling functional movement and potentially improving rehabilitation outcomes in sports injuries and neurological diseases. Researcher...
Researchers have developed a new class of engineered nanoparticles that can bind to and degrade specific disease-related proteins. This technology has the potential to treat diseases such as dementia and brain cancer by eliminating harmful proteins.
Researchers have made progress in creating human milk oligosaccharides through bioengineering, enabling the industrial-scale production of complex HMOs. This allows infant formula to mimic human milk's compositional complexity, potentially offering benefits for gut microbiota development and immune protection.
Engineers at Washington University in St. Louis have discovered the cause of fluctuating metabolic activity in microorganisms and developed strategies to optimize bioproduction. They found that fluctuations in enzyme expression account for most of the variability in betaxanthin production.
Researchers have developed a new method to print custom microstructures directly into living cells, enabling the study of biological functions and instilling enhanced properties. The breakthrough uses light-sensitive materials and laser polymerization to create structures within cells.
Researchers developed a new technique called CLASSIC that enables large-scale testing of complex DNA circuits in human cells. The approach uses artificial intelligence and machine learning to analyze vast numbers of complete circuits at once, providing scientists with a clearer picture of the rules governing genetic part behavior.
The CRISPR-Cas3 system has been shown to induce reliable and extensive deletions of the TTR gene in mouse models of ATTR, reducing serum TTR levels by up to 80%. This technology holds promise for treating not onlyATTR but also other incurable inherited diseases.
Combining enzymes with biochar breaks down pollutants into less harmful compounds, improving efficiency and durability. Biochar-immobilized enzymes have demonstrated impressive results in water treatment and soil remediation.
Cyanobacteria can absorb and break down guanidine, using it as their sole nitrogen source, according to a new study. The ability to utilize guanidine is an advantage for colonization, despite its previous classification as a toxic substance.
Researchers developed an artificial saliva containing sugarcane protein, CANECPI-5, to aid in treating teeth of patients with head and neck cancer. The solution significantly reduced bacterial activity and tooth demineralization when combined with fluoride and xylitol.
Researchers developed a lightweight, self-powered eye-tracking system that runs off the energy generated through blinking. The system detects eye movements with high precision and can be used to enable people with mobility impairments such as ALS to control wheelchairs or communicate by moving only their eyes.
Researchers from Shinshu University used ribosome engineering to modify probiotic Lacticaseibacillus rhamnosus GG, resulting in increased colonization and enhanced immune stimulation. The engineered bacteria exhibit altered surface protein expression and induce higher activation of immune cells.
The researchers created tiny, microorganism-inspired particles that can change their shape and self-propel in response to electrical fields. These particles could be used as microrobots to deliver medications or build dynamic materials that are responsive and self-healing.
Researchers combined Dynamic Optical Contrast Imaging (DOCI) with machine learning to identify thyroid cancer during surgery. The AI analysis framework accurately classified samples across three categories and generated tumor probability maps for precise location identification.
Researchers have engineered grasses to produce a purple pigment in response to specific chemical cues, allowing for non-destructive detection of chemical exposure. This breakthrough enables plants to act as sentinels in the field, reporting adverse conditions that may impact crop and human health.
Researchers create a novel mathematical framework to control biological noise, enabling precise single-cell control. The 'Noise Robust Perfect Adaptation' technology suppresses stochastic fluctuations while maintaining stable average behavior, with promising applications in cancer therapy and synthetic biology.
A new study introduces a 'theragnostic' agent that combines therapy and diagnosis for ischemic stroke. The engineered extracellular vesicles demonstrate dual capability of dynamic monitoring and synergistic therapy, tracking restoration of vascular integrity and reducing infarction volume.
Researchers found that adding biochar with beneficial microorganisms like Trichoderma significantly reduced cadmium stress in crops while improving soil health. The combination restored photosynthetic capacity, biomass production, and enzyme activity, making it a promising solution for sustainable agriculture and soil remediation.
A research team at URV developed a method to analyze biochemical changes in nearby leaves to predict fruit ripeness. This technique allows for reliable information about the fruit's developmental state without damaging it.
A study analyzed large-scale human ChIP-seq data to identify unmeasured transcription factor-tissue/cell type pairs, revealing significant gaps in current knowledge. These findings indicate that essential regulatory mechanisms may have been overlooked, emphasizing the need for strategic prioritization of measurement targets.
Researchers at Osaka Metropolitan University engineered yeast to produce 122 times more 2,3-butanediol in high-concentration environments. Gene expression analysis revealed the crucial role of proteasome and peroxisome activation in tolerance.
Researchers discover RFP's role in adipogenesis, a process that forms fat-storing cells. The study found that high RFP levels promote easy fat cell formation and weight gain, while low levels resist weight gain.
Researchers have created a novel synthetic enzyme that efficiently converts CO2 into formic acid, opening up new possibilities for biotechnological production of valuable chemicals and fuels. The enzyme, FAR, tolerates high concentrations of formate and is stable in both living cells and cell-free systems.
Jeonbuk National University researchers examine how different seasonings shape kokumi perception in doenjang soup, influencing consumer acceptance. They found that umami is a major sensory driver of kokumi perception and can be enhanced to improve the flavor quality of fermented foods.
Philip R. Troyk, director of the Pritzker Institute of Biomedical Science and Engineering at Illinois Tech, has been elected as a Fellow of the National Academy of Inventors for his groundbreaking work on neuroprosthetic devices, including an implanted cortical visual prosthesis that provides artificial vision to individuals with profo...
A newly developed wearable sensor uses polarized light to improve photoplethysmography (PPG) signal accuracy across different skin tones. The device splits light into two channels, detecting co-polarized and cross-polarized signals to filter out superficial scattering and capture stronger signals from deeper tissue.
Researchers found that a mitochondrial protein called COX7RP increases healthy lifespan in mice by improving its mitochondrial energy efficiency. The study also showed improved glucose homeostasis, healthier lipid profiles, enhanced muscle endurance, and lower fat accumulation in the liver.
Researchers at ETH Zurich have developed a solution to introduce artificial amino acids into bacteria efficiently. By hijacking a natural transport system, they can produce designer proteins with unnatural amino acids just as efficiently as their natural counterparts. This breakthrough enables the expansion of the 'amino acid toolbox' ...
Researchers developed a novel bioelectronic material that transforms from a rigid film to a soft, tissue-like interface upon hydration, enabling seamless integration with living tissues. The device, called THIN, has been shown to record biological signals with high fidelity and stability in animal experiments.
Researchers used CRISPR technologies to discover previously unannotated DNA stretches in the 'dark genome', which control cell response to mechanical properties of their environment. This work could lead to new therapeutic targets for illnesses involving changes to tissue mechanics, including fibrosis and cancer.
Researchers at TUM have developed a method to boost oxidase biosensor accuracy from 50% to 99%, paving the way for new uses in personalized medicine, AI-driven healthcare, and agriculture. This breakthrough could enable on-site adjustments to fertilization, reducing environmental impact.
Researchers at Case Western Reserve University improved electrode performance in brain-computer interfaces by delivering anti-inflammatory drugs directly to the site of implantation using platelet-inspired nanoparticles. The breakthrough has potential applications for treating various diseases involving inflammation and vascular injury.
University of Houston engineers have discovered that melatonin helps plants grow by adjusting biological processes to coincide with daily cycles. The hormone also enhances photosynthesis and improves stress tolerance in crops.
A new advance in EEG imaging technology has improved mapping for epilepsy surgery, providing an accurate and non-invasive method. Pathological HFOs were found to be the most accurate biomarker for identifying epileptogenic brain regions, allowing for precise localization of seizure onset.
Scientists developed a wireless device that uses light to send information directly to the brain, bypassing natural sensory pathways. The soft device delivers precise patterns of light through the bone to activate neurons across the cortex, allowing mice to learn and interpret meaningful signals.
Researchers at Emory University uncover how deep-sea microbes create complex structures through a simple process, driving chaperone-free polymerization of archaeal cannulae. This discovery sheds light on the unique adaptations of extremophiles, which thrive in extreme environments.
Researchers at Science Tokyo have developed a tunable deterministic lateral displacement (DLD) cell-sorting platform using poly(N-isopropylacrylamide) hydrogel arrays. The device sorts cancer cells of defined sizes from blood samples with high-resolution size-based sorting, offering a promising tool for biomedical applications.
Extracellular vesicles can mediate communication between cells and tissues, influencing processes like immune signaling and cancer progression. Researchers have developed a practical, scalable EV-isolation platform that operates without preprocessing steps or specialized equipment.
A research team developed a hydrogel that senses changes in wound pH and responds with antibacterial agents to fight infection. As healing progresses, the gel releases ions supporting angiogenesis and tissue regeneration, achieving over 90% wound closure in just 14 days.
The team created a specialized two-dimensional thin film dielectric designed to replace traditional heat-generating components in integrated circuit chips. This breakthrough aims to reduce the significant energy cost and heat produced by high-performance computing necessary for AI.
Researchers at UBC Okanagan develop an innovative airflow system that captures and removes exhaled aerosols, significantly reducing the probability of infection. The new device outperforms conventional ventilation systems, offering a comfortable and effective solution for indoor spaces.
The Virtual Cell Pharmacology Initiative (VCPI) aims to build the first standardized framework for virtual cell modeling in drug discovery. Ginkgo Datapoints is offering free high-throughput RNA profiling via its platform, generating over 12 billion data points and aiming to test at least 100,000 compounds.
Researchers have developed a gene editing technique that allows for the creation of tumor cells with silenced genes in mice without triggering an immune response. This enables the study of metastasis regulators and potential new targets for cancer therapies.
The partnership aims to co-develop and evaluate next-generation self-amplifying RNA (saRNA) vaccines targeting seasonal and pandemic influenza. Apriori's Octavia platform will be combined with A*STAR IDL's saRNA delivery technology to develop improved H5 influenza vaccines that anticipate infection in humans.
A new heart monitoring system featuring dry 3D-printed electrodes and AI software can diagnose up to 10 types of arrhythmias, reducing testing time and medical waste. The system's reusable design improves patient comfort and compliance during long-term monitoring.
Researchers created a miniaturized replica of carotid arteries using 3D printing, mimicking the geometry and fluid dynamics of human blood vessels. The model revealed that platelet movement is crucial in blood clot formation, and high stress on blood vessels triggers significant platelet activity.
Researchers have successfully engineered functional brain-like tissue without animal-derived materials, opening doors to more controlled and humane neurological drug testing. The new material functions as a scaffold for donor brain cells and can be used to model traumatic brain injuries or neurological diseases like Alzheimer's.
Research suggests that health apps, wearables, and interactive programs can improve physical activity, diet, and weight outcomes for children and teens. Mobile apps had the greatest impact on diet and weight outcomes, while wearables were most effective for reducing sedentary time.
A systematic review examines the current landscape in data processing flow, multimodal fusion strategy, and model architecture for affective computing. Deep learning methods are shown to extract feature representations with high consistency across public datasets and self-collected data.
Researchers have made significant advances in genetically modified plants that produce alpha-amylase inhibitor proteins, making them indigestible to pests like bedbugs, beetles, weevils, and woodworms. Gene editing techniques, such as CRISPR, offer a promising solution to combat insect pests without compromising human consumption.
Researchers at Hosei University developed a hydroponic cultivation system using LED lighting to produce high-quality edamame consistently throughout the year. The nutrient film technique (NFT) method resulted in higher yields, better nutritional value, and increased productivity compared to traditional open-field cultivation.
The partnership designates JMIR Bioinformatics and Biotechnology as the official journal of MCBIOS, ensuring high-visibility publication of cutting-edge bioinformatics research. The agreement also provides benefits such as a discount on article processing fees and virtual education and training for MCBIOS members.
Scientists from Delft University of Technology have developed living materials that can detect disease biomarkers, catalyze environmental pollutant breakdown, and function as self-healing composites. The materials are made by embedding bacterial spores in a protective barrier and can be programmed to perform specific tasks.
A nonsurgical approach has been demonstrated to quiet a specific brain circuit in an animal model by delivering engineered gene therapy only to the targeted region. The method uses low-intensity focused ultrasound to open the blood-brain barrier, allowing precise control over brain activity without impacting off-target areas.