Articles tagged with Biotechnology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed a novel exoskeleton CASIA-EXO with subject-adaptive control, enabling efficient motor relearning and enhancing neural plasticity. The system uses intention-based trajectory planning and performance-based intervention adaptation to individualize training trajectories and intervention levels.
Scientists at Southwest Research Institute (SwRI) have successfully replicated induced Pluripotent Stem Cells (iPSCs) using a new application of their cell-expansion bioreactor. The bioreactor's unique geometry allows for the growth of large quantities of iPSCs, which can differentiate into any other cell type in the body.
Computationally predicted protein target sites offer a strategic pathway for disease mechanism elucidation and therapeutic acceleration. Advanced frameworks like Markov State Models and Gaussian accelerated MD enable exploration of long-timescale dynamics.
Genetic engineers design gene circuits to program cells with new functions, but dilution causes loss of function. Researchers use liquid-liquid phase separation to form transcriptional condensates around genes, protecting genetic programs and maintaining stability across cell generations.
Researchers uncover tandem allosteric effect enabling efficient deacetylation of proteins by Sir2, a key enzyme for biological processes. This finding reveals new target for modulating Sir2, potentially leading to novel cancer treatments and therapeutic applications.
The BioHub aims to complete over 24 pilot projects, train over 500 individuals, and create 3,000 new jobs within three years. Powered by breakthroughs in genetics, genomics, process engineering, and artificial intelligence, Central Massachusetts is poised to lead a new era of biology-based manufacturing.
Binghamton University scientists have developed a novel bioelectronics material that combines living liquid metal with electrogens to create next-generation devices. This innovation has the potential to revolutionize fields such as biomedical sensing and device integration.
Researchers have identified iron-manganese alloys as promising candidates for temporary bone fixation. These alloys combine strength, biocompatibility, and degradation properties, allowing them to support bone healing while degrading naturally. However, challenges remain, including controlling the release of manganese, which can pose t...
Advanced molecular dynamics simulations model complex RNA structures with high accuracy, enabling potential applications in RNA-based therapies and drug design. The study successfully simulated the folding of diverse RNA stem loops, revealing a distinct folding pathway for challenging motifs.
Dr. Xin Jin has been recognized for her groundbreaking work on genetic mechanisms of neurodevelopmental disorders, developing new technologies to accelerate the understanding of gene mutations in the brain. Her research aims to uncover fundamental principles of genome function and its impact on neural systems.
A team of scientists has successfully developed a new method for producing large amounts of xanthommatin pigment in the lab, using a nature-inspired approach. This breakthrough could lead to the creation of camouflage-inspired materials and cosmetics, as well as alternative materials for industries moving away from fossil fuels.
Researchers have successfully produced high-performance fibers from fermentation waste, offering a sustainable alternative to traditional materials. The new fiber requires significantly less water and land than cotton, making it an attractive solution for reducing the environmental impact of the fashion industry.
Researchers at ETH Zurich have successfully produced muscle tissue using a new biofabrication system called G-FLight in microgravity. The process enables rapid production of viable muscle constructs with similar cell viability and muscle fibers as those printed under gravity.
Australian researchers have developed tiny compartments to help supercharge photosynthesis, enabling plants to fix carbon more efficiently. The team engineered encapsulins that can house the enzyme Rubisco in a confined space, allowing for fine-tuning of compatibility for future use in crops.
A breakthrough gene atlas for oats has been developed, which could help plant breeders create better oat varieties with improved health benefits and climate resistance. The atlas will significantly expand genomic resources available to researchers.
A team of biomechanical engineers and surgeons has developed a 3D-printing soft robot that can accurately deliver hydrogels to the vocal cord surgical site. The device, which is only 2.7 mm in size, can reconstruct tissues removed during surgery and potentially prevent fibrosis and stiffening of the vocal cords.
Researchers at the University of São Paulo developed a low-cost, portable biosensor that can quickly identify altered levels of BDNF associated with psychiatric disorders. The device detects extremely low concentrations of BDNF in human saliva, which is crucial for growth and maintenance of neurons and development of brain functions.
A new study suggests that collecting and testing cancer cells in patients' blood could help doctors choose the right breast cancer treatment. The 'labyrinth chip' technology separates cancer cells from other blood cells, allowing researchers to identify biomarkers that distinguish aggressive treatments from less invasive ones.
The partnership creates a stable, high-impact venue for MCBIOS members to publish their research, particularly the output from the Society's annual conference. The designation of JMIR Bioinformatics and Biotechnology as the official journal provides maximum visibility for cutting-edge work in bioinformatics and computational biology.
A team of Pitt engineers has created self-powered spinal implant technology capable of transmitting real-time data from inside the body. The innovation utilizes new human-developed composites known as metamaterials to harvest energy and transmit signals wirelessly.
Researchers from The University of Osaka and The University of Tokyo have developed a novel technology that visualizes specific molecules inside living cells using light. The new photo-responsive alkyne tag enables precise visualization without disrupting molecular dynamics.
Researchers have developed biochar-supported microbial systems to tackle persistent organic pollutants, including polycyclic aromatic hydrocarbons and pesticides. These integrated strategies have achieved impressive results, breaking down pollutants in industrial wastewater, agricultural soils, and domestic environments.
Researchers at UC San Diego have discovered a new way to make yeast cells more efficient 'cell factories' for producing valuable plant compounds. The advance enables the sustainable manufacturing of plant-derived chemicals used to help plants defend against disease, repel pests, attract pollinators, and withstand environmental stresses.
The Stowers Institute has appointed its first AI Fellow, Sumner Magruder, to harness the potential of artificial intelligence in biological research. He will collaborate with researchers to design new algorithms and unlock insights from large datasets.
Researchers at the University of Texas at Austin have developed a novel gene-editing method that can correct multiple disease-causing mutations simultaneously. This approach uses bacterial retrons to protect the microbes from viral infection and has shown promising results in correcting scoliosis-causing mutations in zebrafish embryos.
The Science/Science Careers' 2025 Top Employers Survey ranked the top companies in biotechnology, biopharmaceuticals, and pharmaceuticals based on employee responses. The survey found that companies with strong reputations as employers prioritized innovation, leadership, and work culture.
A Moroccan ICU study shows that the plethysmographic perfusion index can help identify fluid responsiveness in critically ill patients with acute circulatory failure non-invasively. Two-thirds of patients were fluid responders, and PPI correctly identified responders with 70% sensitivity and 82% specificity.
Researchers create enhanced T cells with improved survival in cancer models by simultaneously modifying multiple genes using CRISPRoff and CRISPRon. The approach overcomes toxicity issues associated with traditional gene editing methods, enabling high cell survival rates and potential for treating various diseases.
Researchers developed sulfated yeast to adsorb targeted elements from solutions, absorbing 2.3 times more copper than previous phosphate-modified baker's yeast. The new method effectively desorbs and re-adsorbs metals using hydrochloric acid, providing a sustainable solution for rare earth recovery.
Researchers developed a technology to detach cells from surfaces on demand, reducing waste and improving workflow in industrial processes. The system uses electrochemically generated bubbles to separate cells without damaging them, paving the way for more efficient CO2 absorption and lifesaving cell therapies.
Researchers at MIT have developed a new system that allows for precise control over the expression of synthetic genes in cells. The DIAL system uses a promoter editing mechanism to establish desired protein levels, which can be edited after delivery. This technology has the potential to improve gene therapy and cell reprogramming appli...
A bioactive compound produced by Bacillus licheniformis has antioxidant, emulsifying, and stabilizing properties. Its exopolysaccharide production is beneficial for producing biodegradable materials, and its functional properties surpass those of commercial xanthan gum.
A team of UCF researchers is creating a single low-cost test to detect multiple viruses simultaneously, which may be used in resource-limited settings. The test has the potential to save lives by providing quicker and more accessible results.
A new menstrual cup has been developed with a flushable tablet made from seaweed-based material to hold menstrual blood and minimize spills. The product complements the existing Bfree Cup and has potential for wearable health monitoring capabilities.
Researchers designed proteins with autonomous decision-making capabilities, controlling their localization based on environmental cues. This breakthrough enables more finely targeted drug delivery, reducing off-target effects and improving therapy efficacy.
Researchers have generated a new ring-shaped protein nanomaterial capable of strongly binding to and neutralizing the SARS-CoV2 virus. The system can integrate therapeutic and diagnostic capabilities and be adapted to combat other viruses.
A new AI-based system helps researchers design polymers with tailored electronic properties for next-generation bioelectronics. By processing a wide range of experiments, the system reveals the importance of local polymer order and dopant-polymer separation in controlling electronic properties.
The bregr R package streamlines the process of analyzing large-scale biomedical data by automating model fitting, extracting tidy results, and providing publication-quality visualizations. This results in enhanced efficiency and scalability for researchers, while maintaining reproducibility and accuracy.
Researchers at Saarland University have developed a process that transforms hard-to-recycle polystyrene into a sought-after feedstock for high-quality technical and high-performance polymers. This 'biological upcycling' enables the production of nylon precursors, offering a clear advantage over conventional recycling.
Researchers designed long-acting human albumin-fused FIX variants with unique pharmacokinetic properties, including extended plasma half-lives and enhanced extravascular distribution. The findings endorse the use of engineered albumin-fused FIX variants as personalized therapy options for hemophilia B.
Researchers developed a porous carbon catalyst, OAL1-650, which achieved high removal rates (90%) and mineralization rates (79.8%) for sulfamethoxazole degradation using peroxymonosulfate activation. Oxalic acid activation increased surface area and introduced C=O functional groups, key active sites for ROS generation.
Researchers found that pairing biochar with biogas slurry reduces CO2 emissions and alters soil microbial communities, enhancing carbon sequestration. However, the combination also increases CH4 emissions, highlighting a tradeoff.
The NF-κB signaling pathway plays a key role in regulating immune responses, inflammation, cell development, and proliferation. Research into its functions and mechanisms continues to uncover new breakthroughs in immunology and life sciences.
Biomedical engineers at Duke University developed a platform combining automated wet lab techniques and AI to design nanoparticles for drug delivery. The TuNa-AI platform resulted in a 42.9% increase in successful nanoparticle formation compared to standard approaches.
A new 3D imaging technique combines intensity diffraction tomography with adaptive optics to track subcellular structures over extended periods. This approach achieves high spatiotemporal resolution and molecular specificity, enabling the study of cellular dynamics.
Researchers at CU Boulder have developed a new method for creating human rabies vaccines that are stable at high temperatures and can be stored in a dry powder form. This innovation addresses the storage challenges faced by developing countries, where traditional vaccines often require refrigeration or specialized cold storage equipment.
A wearable device called a-Heal optimizes each stage of the wound healing process using AI and bioelectronics, delivering medication or an electric field for personalized treatment. Initial preclinical results show the device speeds up the healing process by 25% compared to standard care.
A new high-throughput screening approach has enhanced CRISPR genome-editing efficiency by identifying promising CAST variants. The method allows for rapid optimization of these candidates, uncovering mechanistic insights that can inform further engineering and potential clinical use.
Two projects funded by federal grants use AI to design proteins for industrial applications, such as producing acrylates in paints. UC Davis will also expand its student training program in protein design to bring hands-on research opportunities to thousands of students nationwide.
A research team led by Professor Shikha Dhiman has discovered that the speed of receptors in model cell membranes plays a crucial role in binding to biomaterials. When ligands move at similar speeds, they can bind to receptors, enabling effective tissue engineering and medical applications.
Researchers found that highly conductive biochar produces up to 69% more methane in rice soils due to faster electron transfer. The study highlights the importance of biochar's physical properties in determining its impact on greenhouse gas emissions.
Researchers at Graz University of Technology created a highly detailed digital twin of the A549 lung cancer cell line, paving the way for individualized cancer treatment. The model simulates calcium dynamics and electrical voltages, allowing for testing of drugs and personalized treatment strategies.
A new study shows that remote perioperative monitoring significantly improves recovery for cancer surgery patients, with a 6% greater functional recovery rate by day 14 after surgery. The study also found fewer major complications and improved symptom management.
Researchers developed a novel 3D printing technique that combines materials and design to create strong, biocompatible implants. The study found that varying printing angles and ink composition can significantly impact implant strength and bone cell growth.
Researchers at Tulane University have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, detecting TB in samples with very low levels of bacteria. The new test shows high sensitivity and accuracy, offering a significant step forward toward effective diagnoses via a variety of samples.
Researchers developed DF-FPDT to address low-frequency loss from non-matched illumination in live-cell imaging, enabling high-resolution and high-contrast 3D reconstructions. This breakthrough technique leverages non-matched illumination to enhance structural details without additional hardware or post-processing.
A novel method combining biological experiments and information science techniques reveals cancer cells' preference for aerobic glycolysis despite sufficient oxygen availability. This research provides a powerful tool for identifying metabolic vulnerabilities in cancer cells, which could lead to more effective treatments.
Scientists have achieved a major breakthrough by 3D bioprinting miniature placentas, which can accurately replicate the human placenta. This technology has the potential to transform pregnancy research by allowing for the study of serious complications like preeclampsia.
Researchers synthesized hybrid vitamin K analogues with enhanced neuroactive properties, exhibiting threefold greater potency in inducing neural progenitor cell differentiation compared to natural vitamin K. The compounds preserved vitamin K and retinoic acid's biological activity via the SXR and RAR receptors.
A study by SeoulTech researchers found high levels of polycyclic aromatic hydrocarbons (PAHs) in common food items, including cooking oils and meats. The QuEChERS-GC-MS method revealed carcinogenic compounds with limits of detection ranging from 0.006 to 0.035 µg/kg.