Articles tagged with Biotechnology
A team of biomechanical engineers and surgeons has developed a 3D-printing soft robot that can accurately deliver hydrogels to the vocal cord surgical site. The device, which is only 2.7 mm in size, can reconstruct tissues removed during surgery and potentially prevent fibrosis and stiffening of the vocal cords.
The partnership creates a stable, high-impact venue for MCBIOS members to publish their research, particularly the output from the Society's annual conference. The designation of JMIR Bioinformatics and Biotechnology as the official journal provides maximum visibility for cutting-edge work in bioinformatics and computational biology.
Researchers from The University of Osaka and The University of Tokyo have developed a novel technology that visualizes specific molecules inside living cells using light. The new photo-responsive alkyne tag enables precise visualization without disrupting molecular dynamics.
A team of Pitt engineers has created self-powered spinal implant technology capable of transmitting real-time data from inside the body. The innovation utilizes new human-developed composites known as metamaterials to harvest energy and transmit signals wirelessly.
Researchers have developed biochar-supported microbial systems to tackle persistent organic pollutants, including polycyclic aromatic hydrocarbons and pesticides. These integrated strategies have achieved impressive results, breaking down pollutants in industrial wastewater, agricultural soils, and domestic environments.
Researchers at UC San Diego have discovered a new way to make yeast cells more efficient 'cell factories' for producing valuable plant compounds. The advance enables the sustainable manufacturing of plant-derived chemicals used to help plants defend against disease, repel pests, attract pollinators, and withstand environmental stresses.
The Stowers Institute has appointed its first AI Fellow, Sumner Magruder, to harness the potential of artificial intelligence in biological research. He will collaborate with researchers to design new algorithms and unlock insights from large datasets.
Researchers at the University of Texas at Austin have developed a novel gene-editing method that can correct multiple disease-causing mutations simultaneously. This approach uses bacterial retrons to protect the microbes from viral infection and has shown promising results in correcting scoliosis-causing mutations in zebrafish embryos.
The Science/Science Careers' 2025 Top Employers Survey ranked the top companies in biotechnology, biopharmaceuticals, and pharmaceuticals based on employee responses. The survey found that companies with strong reputations as employers prioritized innovation, leadership, and work culture.
A Moroccan ICU study shows that the plethysmographic perfusion index can help identify fluid responsiveness in critically ill patients with acute circulatory failure non-invasively. Two-thirds of patients were fluid responders, and PPI correctly identified responders with 70% sensitivity and 82% specificity.
Researchers create enhanced T cells with improved survival in cancer models by simultaneously modifying multiple genes using CRISPRoff and CRISPRon. The approach overcomes toxicity issues associated with traditional gene editing methods, enabling high cell survival rates and potential for treating various diseases.
Researchers developed sulfated yeast to adsorb targeted elements from solutions, absorbing 2.3 times more copper than previous phosphate-modified baker's yeast. The new method effectively desorbs and re-adsorbs metals using hydrochloric acid, providing a sustainable solution for rare earth recovery.
Researchers developed a technology to detach cells from surfaces on demand, reducing waste and improving workflow in industrial processes. The system uses electrochemically generated bubbles to separate cells without damaging them, paving the way for more efficient CO2 absorption and lifesaving cell therapies.
A bioactive compound produced by Bacillus licheniformis has antioxidant, emulsifying, and stabilizing properties. Its exopolysaccharide production is beneficial for producing biodegradable materials, and its functional properties surpass those of commercial xanthan gum.
A team of UCF researchers is creating a single low-cost test to detect multiple viruses simultaneously, which may be used in resource-limited settings. The test has the potential to save lives by providing quicker and more accessible results.
Researchers at MIT have developed a new system that allows for precise control over the expression of synthetic genes in cells. The DIAL system uses a promoter editing mechanism to establish desired protein levels, which can be edited after delivery. This technology has the potential to improve gene therapy and cell reprogramming appli...
A new menstrual cup has been developed with a flushable tablet made from seaweed-based material to hold menstrual blood and minimize spills. The product complements the existing Bfree Cup and has potential for wearable health monitoring capabilities.
Researchers designed proteins with autonomous decision-making capabilities, controlling their localization based on environmental cues. This breakthrough enables more finely targeted drug delivery, reducing off-target effects and improving therapy efficacy.
Researchers have generated a new ring-shaped protein nanomaterial capable of strongly binding to and neutralizing the SARS-CoV2 virus. The system can integrate therapeutic and diagnostic capabilities and be adapted to combat other viruses.
A new AI-based system helps researchers design polymers with tailored electronic properties for next-generation bioelectronics. By processing a wide range of experiments, the system reveals the importance of local polymer order and dopant-polymer separation in controlling electronic properties.
The bregr R package streamlines the process of analyzing large-scale biomedical data by automating model fitting, extracting tidy results, and providing publication-quality visualizations. This results in enhanced efficiency and scalability for researchers, while maintaining reproducibility and accuracy.
Researchers at Saarland University have developed a process that transforms hard-to-recycle polystyrene into a sought-after feedstock for high-quality technical and high-performance polymers. This 'biological upcycling' enables the production of nylon precursors, offering a clear advantage over conventional recycling.
Researchers developed a porous carbon catalyst, OAL1-650, which achieved high removal rates (90%) and mineralization rates (79.8%) for sulfamethoxazole degradation using peroxymonosulfate activation. Oxalic acid activation increased surface area and introduced C=O functional groups, key active sites for ROS generation.
Researchers found that pairing biochar with biogas slurry reduces CO2 emissions and alters soil microbial communities, enhancing carbon sequestration. However, the combination also increases CH4 emissions, highlighting a tradeoff.
Researchers designed long-acting human albumin-fused FIX variants with unique pharmacokinetic properties, including extended plasma half-lives and enhanced extravascular distribution. The findings endorse the use of engineered albumin-fused FIX variants as personalized therapy options for hemophilia B.
The NF-κB signaling pathway plays a key role in regulating immune responses, inflammation, cell development, and proliferation. Research into its functions and mechanisms continues to uncover new breakthroughs in immunology and life sciences.
A new 3D imaging technique combines intensity diffraction tomography with adaptive optics to track subcellular structures over extended periods. This approach achieves high spatiotemporal resolution and molecular specificity, enabling the study of cellular dynamics.
Biomedical engineers at Duke University developed a platform combining automated wet lab techniques and AI to design nanoparticles for drug delivery. The TuNa-AI platform resulted in a 42.9% increase in successful nanoparticle formation compared to standard approaches.
A wearable device called a-Heal optimizes each stage of the wound healing process using AI and bioelectronics, delivering medication or an electric field for personalized treatment. Initial preclinical results show the device speeds up the healing process by 25% compared to standard care.
A new high-throughput screening approach has enhanced CRISPR genome-editing efficiency by identifying promising CAST variants. The method allows for rapid optimization of these candidates, uncovering mechanistic insights that can inform further engineering and potential clinical use.
Researchers at CU Boulder have developed a new method for creating human rabies vaccines that are stable at high temperatures and can be stored in a dry powder form. This innovation addresses the storage challenges faced by developing countries, where traditional vaccines often require refrigeration or specialized cold storage equipment.
A research team led by Professor Shikha Dhiman has discovered that the speed of receptors in model cell membranes plays a crucial role in binding to biomaterials. When ligands move at similar speeds, they can bind to receptors, enabling effective tissue engineering and medical applications.
Two projects funded by federal grants use AI to design proteins for industrial applications, such as producing acrylates in paints. UC Davis will also expand its student training program in protein design to bring hands-on research opportunities to thousands of students nationwide.
Researchers found that highly conductive biochar produces up to 69% more methane in rice soils due to faster electron transfer. The study highlights the importance of biochar's physical properties in determining its impact on greenhouse gas emissions.
Researchers at Graz University of Technology created a highly detailed digital twin of the A549 lung cancer cell line, paving the way for individualized cancer treatment. The model simulates calcium dynamics and electrical voltages, allowing for testing of drugs and personalized treatment strategies.
Researchers developed a novel 3D printing technique that combines materials and design to create strong, biocompatible implants. The study found that varying printing angles and ink composition can significantly impact implant strength and bone cell growth.
Researchers at Tulane University have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, detecting TB in samples with very low levels of bacteria. The new test shows high sensitivity and accuracy, offering a significant step forward toward effective diagnoses via a variety of samples.
A new study shows that remote perioperative monitoring significantly improves recovery for cancer surgery patients, with a 6% greater functional recovery rate by day 14 after surgery. The study also found fewer major complications and improved symptom management.
Researchers developed DF-FPDT to address low-frequency loss from non-matched illumination in live-cell imaging, enabling high-resolution and high-contrast 3D reconstructions. This breakthrough technique leverages non-matched illumination to enhance structural details without additional hardware or post-processing.
A novel method combining biological experiments and information science techniques reveals cancer cells' preference for aerobic glycolysis despite sufficient oxygen availability. This research provides a powerful tool for identifying metabolic vulnerabilities in cancer cells, which could lead to more effective treatments.
Scientists have achieved a major breakthrough by 3D bioprinting miniature placentas, which can accurately replicate the human placenta. This technology has the potential to transform pregnancy research by allowing for the study of serious complications like preeclampsia.
Researchers synthesized hybrid vitamin K analogues with enhanced neuroactive properties, exhibiting threefold greater potency in inducing neural progenitor cell differentiation compared to natural vitamin K. The compounds preserved vitamin K and retinoic acid's biological activity via the SXR and RAR receptors.
A study by SeoulTech researchers found high levels of polycyclic aromatic hydrocarbons (PAHs) in common food items, including cooking oils and meats. The QuEChERS-GC-MS method revealed carcinogenic compounds with limits of detection ranging from 0.006 to 0.035 µg/kg.
Researchers developed wearable microneedle patches that improve drug absorption while reducing pain in long-term delivery. The new technology, inspired by bee stings, enables continuous drug release and anchors securely into the skin.
Researchers developed a method to identify causal relationships between neurons solely based on spike train data, providing a new tool for understanding brain connectivity. The approach accurately detected bidirectional and unidirectional coupling between neurons, even in the presence of internal noise.
Engineered cell lines are prone to misidentification, threatening scientific discoveries and intellectual property. Researchers at UT Dallas have developed a novel method to embed unique genetic identifiers, eliminating identification errors and safeguarding innovations with tamper-proof genomic tags.
Researchers from Osaka Metropolitan University discovered a novel light-sensing mechanism in reef-building corals, where opsins use chloride ions as counterions to detect visible light. This unique functionality suggests that coral light sensitivity can adjust according to the algae's photosynthetic activity.
Researchers at Harvard SEAS have developed a gentler, more sustainable way to break down keratins and turn leftover wool and feathers into useful products. The process uses concentrated lithium bromide to create an environment favorable for spontaneous protein unfolding.
Researchers Theresa Rienmüller and Robert Winkler from Graz University of Technology have been awarded prestigious funding prizes for their innovative projects. Rienmüller is investigating electrical stimulation as a therapy for traumatic brain injury, while Winkler is developing micro-robots that could treat diseases in the human body...
Scientists have developed a new computational method to build the first 4D lipid map of a vertebrate embryo, capturing how lipid distributions change over time. The atlas reveals organized patterns of lipids that match anatomical structures, suggesting key roles in shaping organ function and identity.
Researchers at ETH Zurich discovered that cancer cells can transfer their mitochondria to healthy fibroblasts, reprogramming them into tumour-associated fibroblasts that support cancer cell growth. The mitochondrial transfer mechanism involves the protein MIRO2, which is produced in high quantities in cancer cells.
Researchers at EPFL developed BindCraft, an open-source AI platform that uses AlphaFold2 to generate novel binders with desired functional properties. The platform reduces the need for high-throughput screening and makes protein design more democratized.
The system uses magnetoelectric power-transfer technology to deliver precise electrical stimulation to organs like the heart and spinal cord. The more devices in the network, the more efficient it is, offering a less invasive alternative to traditional implantable medical devices. This technology has potential for treating conditions s...
Researchers developed novel sweat sensors that mimic the microtexture of rose petals, enhancing stability, performance, and comfort. The sensors demonstrate a self-cleaning effect, reducing skin irritation and improving user comfort, making them suitable for wearable devices like smartwatches.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
The global market for AI in pharmaceuticals is projected to reach $13.4 billion by 2035, driven by Insilico Medicine's innovative use of generative AI. The company will share its achievements at a satellite forum during BIOHK2025, showcasing significant efficiency boosts compared to traditional methods.
A new study introduces an optical imaging technique that uses autofluorescence to detect colorectal cancer in real time, offering a promising tool for improving cancer detection during endoscopic procedures. The technique achieved high accuracy rates and the potential to guide doctors during colonoscopy or surgery.
Researchers at Osaka Metropolitan University have discovered that delaying fertility drug administration to match follicle maturity period increases ovulated oocytes and normal offspring development. This study contributes to understanding infertility treatments and potential applications for humans and endangered species.
Researchers developed a machine learning model that accounts for biological variability to identify optimal formulations for serum-free culture media. The model achieved approximately 1.6-fold higher cell density compared to commercially available products.
The Northern Virginia International Soft Landing Accelerator (NISA) brings global expertise to the region's thriving ecosystem. NISA gives startups tools to reach markets, connect with investors, and flourish, with funding from GO Virginia and regional economic development groups.