Articles tagged with Biotechnology
The partnership aims to accelerate biomedical innovation through joint research programs, faculty collaboration, and expanded student training opportunities. Researchers will have access to shared laboratory infrastructure, reciprocal faculty affiliations, and joint grant proposals.
Researchers developed a method called optovolution that uses light to guide the evolution of proteins with dynamic, multi-state, and computational functions. This approach favors variants with better dynamics, allowing for the creation of new variants with improved light sensitivity and responsiveness.
A novel plant-based approach uses lettuce chloroplasts to produce functional GLP-1 peptides, paving the way for more affordable and better-tolerated oral medications. This method bypasses hurdles such as manufacturing cost, delivery system, and side effects associated with conventional approaches.
A recent study has shed light on the processes that drive mitochondrial uptake and its benefits for cells. Isolated mitochondria were found to be taken up by mesenchymal stromal cells, enhancing proliferation and cytoprotection, and improving energy metabolism.
Researchers at Simon Fraser University have developed a new, fully customizable 3D printed socket design that combines pressure mapping with AI software and a lighter infill. This innovation has shown improved comfort and reduced common complications for prosthetics wearers.
Scientists at Institute of Science Tokyo have discovered how LGP2 and MDA5 work together to recognize viral RNA. The study reveals that LGP2 binds to the ends of a dsRNA molecule, recruiting MDA5 molecules behind it and forming filament-like structures, ultimately triggering an innate immune response.
Researchers used machine learning techniques to compress a large model of the visual cortex, creating smaller versions that predict neural responses with high accuracy. The compact models revealed specific computational patterns in how neurons detect important features, offering insights into how visual information is processed.
Researchers have identified new microbial species in corals that produce unique natural products, offering a vast arsenal of potential benefits to humanity. The study highlights the importance of protecting coral reefs' microbiomes to tap into this untapped resource before it's lost forever.
Researchers at Washington University in St. Louis have created protein fibers that can exhibit high tensile strength, toughness, and mechanical stability, making them suitable for active wear and biomedical implants. The materials are grown using synthetic biology approaches and can be processed into a meat-like structure.
Researchers at Penn State have developed a bio-hybrid system that combines synthetic DNA with perovskite semiconductors to create a memory resistor that stores and processes data with minimal power consumption. This technology has the potential to enable more efficient data centers, speedier data processing and more complex data analysis.
A new machine learning model interprets leg motion as expended energy, providing a more accurate measure of calories burned. The device has been shown to have double the accuracy of commercial smartwatches and activity trackers.
Researchers at Harvard's John A. Paulson School of Engineering and Applied Sciences have developed a new fabrication method for printing robotic devices with long filaments featuring precisely placed hollow channels. This allows the device to bend and deform in predetermined ways, enabling the creation of soft robots with predictable s...
Researchers have developed a new device that can record and stimulate activity across the entire surface of miniature, lab-grown human brain-like tissues, enabling whole-network mapping and manipulation. This breakthrough could improve our understanding of brain development, function, and disease.
The journal explores the convergence of computational biology, artificial intelligence, and healthcare innovation, with a focus on precision medicine and enhanced patient care. Submissions are accepted from researchers, clinicians, and technologists on topics such as AI in medicine, computational genomics, and drug discovery.
POST-PURPLE aims to convert urban wastewater and organic waste into valuable resources through innovative bio-based technologies. The project will demonstrate practical pathways toward cleaner, more circular urban biorefineries and reduce diffuse emissions.
A study by University of Texas at Dallas bioengineers found that both cancerous and noncancerous colon tissue from young patients with colorectal cancer was mechanically stiffer than in older patients. This stiffness may promote the development of early-onset colorectal cancer, a condition rising over the past 30 years.
Kobe University scientists have engineered bacteria to produce a group of compounds with promising pharmacological activities. The breakthrough uses a rational design strategy to create a platform for industrial production of drug candidates.
60Nd, a UC3M spin-off, develops NeoMag to study tumor behavior, traumatic brain injuries, and wound healing processes. The technology enables researchers to replicate physical disease behaviors and identify new therapeutic targets.
A study published in Carbon Research reveals that a unique Ca-modified biochar can act as a powerful catalyst for the composting process, transforming pig manure and rice straw into stable, nutrient-rich humus. The innovation helps improve waste management in tropical regions, reducing nitrogen loss and environmental footprint.
A research team has developed a 'SUPER' platform that utilizes synthetic small RNAs as add-on controllers for genetic switches. This technology enhances the performance and stability of gene regulatory devices by addressing the issue of 'leakage', where genes continue to express at low levels even in the 'OFF' state.
Researchers developed a light-sensitive oligonucleotide probe that selectively detects 5-formylcytosine, an epigenetically important intermediate. The probe demonstrates stable cross-linking with 5fC across various conditions, enabling its detection in target DNA and complex biological samples.
ASU researchers use DNA to store and protect information in fundamentally new ways, offering a nature-inspired alternative to silicon-based solutions. The approach uses tiny DNA structures that act like physical letters to record and analyze electrical signals, providing high accuracy and scalability.
Researchers have discovered that endophytic bacteria can coexist with plant cells without harming them, triggering the production of previously unattainable compounds. This method has the potential to expand the diversity of obtainable plant-derived compounds for various industries.
Lipid droplets regulate diverse cellular processes in cancer, including membrane biosynthesis and metabolic homeostasis. Targeting lipid metabolism may disrupt tumor survival and counteract immune cell-mediated protumorigenic effects.
Researchers created a 3D chip platform called ASTEROIDS that mimics human physiology and enables precise testing of new drugs and personalized medicine models. The technology has the potential to reduce animal testing in cancer research and improve human clinical outcomes.
Researchers at Sultan Qaboos University successfully demonstrated large-scale spirulina production under local conditions, reducing reliance on imported nutritional products. The project opens opportunities for industry collaboration and contributes to national goals of sustainability, food resilience and economic diversification.
Researchers have developed a flexible, hair-like device that tracks vital signs of a fetus in real-time during surgery. This innovation provides continuous monitoring without invasive access, enabling faster interventions to prevent complications.
The American Association for the Advancement of Science (AAAS) has partnered with Research Networks to publish Computational and Structural Biotechnology Journal, Computational and Structural Biotechnology Reports, and Brain Organoid & Systems Neuroscience Journal as Science Partner Journals. These journals will publish high-quality re...
A new theory of proprioception challenges traditional understanding by incorporating frontier bionic evidence. The proposed framework reconceptualizes proprioception as a dynamic augmentable interface, enabling functional movement and potentially improving rehabilitation outcomes in sports injuries and neurological diseases. Researcher...
Researchers have developed a new class of engineered nanoparticles that can bind to and degrade specific disease-related proteins. This technology has the potential to treat diseases such as dementia and brain cancer by eliminating harmful proteins.
Researchers have made progress in creating human milk oligosaccharides through bioengineering, enabling the industrial-scale production of complex HMOs. This allows infant formula to mimic human milk's compositional complexity, potentially offering benefits for gut microbiota development and immune protection.
Engineers at Washington University in St. Louis have discovered the cause of fluctuating metabolic activity in microorganisms and developed strategies to optimize bioproduction. They found that fluctuations in enzyme expression account for most of the variability in betaxanthin production.
The CRISPR-Cas3 system has been shown to induce reliable and extensive deletions of the TTR gene in mouse models of ATTR, reducing serum TTR levels by up to 80%. This technology holds promise for treating not onlyATTR but also other incurable inherited diseases.
Researchers have developed a new method to print custom microstructures directly into living cells, enabling the study of biological functions and instilling enhanced properties. The breakthrough uses light-sensitive materials and laser polymerization to create structures within cells.
Researchers developed a new technique called CLASSIC that enables large-scale testing of complex DNA circuits in human cells. The approach uses artificial intelligence and machine learning to analyze vast numbers of complete circuits at once, providing scientists with a clearer picture of the rules governing genetic part behavior.
Cyanobacteria can absorb and break down guanidine, using it as their sole nitrogen source, according to a new study. The ability to utilize guanidine is an advantage for colonization, despite its previous classification as a toxic substance.
Combining enzymes with biochar breaks down pollutants into less harmful compounds, improving efficiency and durability. Biochar-immobilized enzymes have demonstrated impressive results in water treatment and soil remediation.
Researchers from Shinshu University used ribosome engineering to modify probiotic Lacticaseibacillus rhamnosus GG, resulting in increased colonization and enhanced immune stimulation. The engineered bacteria exhibit altered surface protein expression and induce higher activation of immune cells.
Researchers developed an artificial saliva containing sugarcane protein, CANECPI-5, to aid in treating teeth of patients with head and neck cancer. The solution significantly reduced bacterial activity and tooth demineralization when combined with fluoride and xylitol.
Researchers developed a lightweight, self-powered eye-tracking system that runs off the energy generated through blinking. The system detects eye movements with high precision and can be used to enable people with mobility impairments such as ALS to control wheelchairs or communicate by moving only their eyes.
The researchers created tiny, microorganism-inspired particles that can change their shape and self-propel in response to electrical fields. These particles could be used as microrobots to deliver medications or build dynamic materials that are responsive and self-healing.
Researchers combined Dynamic Optical Contrast Imaging (DOCI) with machine learning to identify thyroid cancer during surgery. The AI analysis framework accurately classified samples across three categories and generated tumor probability maps for precise location identification.
Researchers have engineered grasses to produce a purple pigment in response to specific chemical cues, allowing for non-destructive detection of chemical exposure. This breakthrough enables plants to act as sentinels in the field, reporting adverse conditions that may impact crop and human health.
Researchers create a novel mathematical framework to control biological noise, enabling precise single-cell control. The 'Noise Robust Perfect Adaptation' technology suppresses stochastic fluctuations while maintaining stable average behavior, with promising applications in cancer therapy and synthetic biology.
A new study introduces a 'theragnostic' agent that combines therapy and diagnosis for ischemic stroke. The engineered extracellular vesicles demonstrate dual capability of dynamic monitoring and synergistic therapy, tracking restoration of vascular integrity and reducing infarction volume.
Researchers found that adding biochar with beneficial microorganisms like Trichoderma significantly reduced cadmium stress in crops while improving soil health. The combination restored photosynthetic capacity, biomass production, and enzyme activity, making it a promising solution for sustainable agriculture and soil remediation.
A research team at URV developed a method to analyze biochemical changes in nearby leaves to predict fruit ripeness. This technique allows for reliable information about the fruit's developmental state without damaging it.
Jeonbuk National University researchers examine how different seasonings shape kokumi perception in doenjang soup, influencing consumer acceptance. They found that umami is a major sensory driver of kokumi perception and can be enhanced to improve the flavor quality of fermented foods.
A study analyzed large-scale human ChIP-seq data to identify unmeasured transcription factor-tissue/cell type pairs, revealing significant gaps in current knowledge. These findings indicate that essential regulatory mechanisms may have been overlooked, emphasizing the need for strategic prioritization of measurement targets.
Researchers at Osaka Metropolitan University engineered yeast to produce 122 times more 2,3-butanediol in high-concentration environments. Gene expression analysis revealed the crucial role of proteasome and peroxisome activation in tolerance.
Researchers discover RFP's role in adipogenesis, a process that forms fat-storing cells. The study found that high RFP levels promote easy fat cell formation and weight gain, while low levels resist weight gain.
Researchers have created a novel synthetic enzyme that efficiently converts CO2 into formic acid, opening up new possibilities for biotechnological production of valuable chemicals and fuels. The enzyme, FAR, tolerates high concentrations of formate and is stable in both living cells and cell-free systems.
Philip R. Troyk, director of the Pritzker Institute of Biomedical Science and Engineering at Illinois Tech, has been elected as a Fellow of the National Academy of Inventors for his groundbreaking work on neuroprosthetic devices, including an implanted cortical visual prosthesis that provides artificial vision to individuals with profo...
Researchers used CRISPR technologies to discover previously unannotated DNA stretches in the 'dark genome', which control cell response to mechanical properties of their environment. This work could lead to new therapeutic targets for illnesses involving changes to tissue mechanics, including fibrosis and cancer.
Researchers at TUM have developed a method to boost oxidase biosensor accuracy from 50% to 99%, paving the way for new uses in personalized medicine, AI-driven healthcare, and agriculture. This breakthrough could enable on-site adjustments to fertilization, reducing environmental impact.
A newly developed wearable sensor uses polarized light to improve photoplethysmography (PPG) signal accuracy across different skin tones. The device splits light into two channels, detecting co-polarized and cross-polarized signals to filter out superficial scattering and capture stronger signals from deeper tissue.
Researchers found that a mitochondrial protein called COX7RP increases healthy lifespan in mice by improving its mitochondrial energy efficiency. The study also showed improved glucose homeostasis, healthier lipid profiles, enhanced muscle endurance, and lower fat accumulation in the liver.
Researchers at ETH Zurich have developed a solution to introduce artificial amino acids into bacteria efficiently. By hijacking a natural transport system, they can produce designer proteins with unnatural amino acids just as efficiently as their natural counterparts. This breakthrough enables the expansion of the 'amino acid toolbox' ...
Researchers developed a novel bioelectronic material that transforms from a rigid film to a soft, tissue-like interface upon hydration, enabling seamless integration with living tissues. The device, called THIN, has been shown to record biological signals with high fidelity and stability in animal experiments.
University of Houston engineers have discovered that melatonin helps plants grow by adjusting biological processes to coincide with daily cycles. The hormone also enhances photosynthesis and improves stress tolerance in crops.