Articles tagged with Biotechnology
Researchers at Ohio State University developed an e-Taste system that uses sensors and chemical dispensers to simulate various tastes. In field testing, participants could distinguish between different sour intensities with high accuracy, paving the way for immersive virtual food experiences.
The article presents guidelines for designing consent materials and procedures for autistic adults and people with intellectual disability, highlighting the importance of multiple modes to deliver content. These guidelines aim to improve accessibility and respectfulness in research with individuals on the autism spectrum.
The article reviews additive manufacturing technology for biomedical metals, enabling customized implants with precise internal structures. It highlights the integration of AI and 4D printing, addressing challenges in production costs, regulatory compliance, and post-processing.
Researchers developed a liquid fertilizer replacing unsustainable chemical fertilizers with organic waste, producing up to 100% of nitrogen and 77% of phosphorus. The method also increases phosphorus solubility by adjusting pH levels.
Researchers at the University of Sydney are using Zwitterions to create materials that can prevent blood clots from forming in medical devices and implants. They have successfully created a zwitterionic coating that repels water beyond the material's boundaries.
Germany's leading biotech hubs, Berlin, Munich, and Heidelberg, excel in different areas, but struggle with transforming research into market-ready solutions. The country's innovation potential is largely untapped due to the fragmentation of its biotech landscape and inadequate knowledge transfer.
Researchers have developed a novel solid catalyst to efficiently reclaim materials from epoxy products, including carbon fibers and glass fibers. The process uses lower temperatures than traditional methods, reducing energy requirements and making the recovery of materials more environmentally friendly.
A new AI-based tool can translate a person's thoughts into continuous text without requiring language comprehension, and it can be trained in under an hour. The system was developed by adapting a previous brain decoder to a new person using short, silent videos.
Researchers developed a next-generation technology, MycoBCP, using artificial intelligence to screen for antimicrobial compound candidates. This method has already vastly accelerated the team's TB research capabilities and helped identify optimal candidate compounds for drug development.
Researchers at U of T have developed a new platform called smol-seq that uses DNA sequencing to detect metabolites. This method enables the analysis of hundreds of metabolites simultaneously, making it faster and more precise than current methods.
Zebrafish have pineal gland photoreceptors that detect color using parapinopsin 1 (PP1) protein. Two genes, Sagb and Arr3a, play a crucial role in the inactivation of PP1 based on light intensity, with Sagb taking over at higher intensities.
Insilico Medicine's AI-driven platform, PandaOmics, identifies two new therapeutic targets and a repurposed FDA-approved drug for treating endometriosis. The study reveals guanylate-binding protein 2 (GBP2) and hematopoietic cell kinase (HCK) as key proteins involved in the disease mechanism.
A new study using a novel mouse strain expressing Halo-tagged SOCS1 reveals that the inhibitor needs to exceed a threshold level to suppress GM-CSF and IFN-gamma signaling. The findings emphasize SOCS1's crucial function in modulating cytokine signaling.
Researchers use SCP-Nano to analyze distribution of extremely low doses of nanocarriers throughout the mouse body, visualizing each cell that has taken them up. The platform identifies unwanted accumulation in organs like the heart and liver, paving the way for safer mRNA therapeutics.
Researchers evaluated the noise impact of offshore wind farms on fishes and dolphins in the Pearl River Estuary. The study found that pile driving noise during construction can significantly affect marine animals, with predicted impact zones varying by species.
Critical Path Institute's Translational Therapeutics Accelerator (TRxA) is launching its 2025 global Request for Proposals to support academic researchers in bridging the 'valley of death' in drug development. The program aims to enable the transition of innovative therapeutics from lab to patients.
Scientists at the University of Stuttgart have developed a new tool for synthetic biology using DNA nanorobots that can alter artificial cells. These nanorobots enable the formation of transport channels in synthetic cell membranes, allowing large molecules to pass through and facilitating the transportation of therapeutic proteins.
The Menarini Group and Insilico Medicine have entered into an exclusive licensing agreement for a preclinical small molecule targeting solid tumor cancers. The asset has demonstrated broad anti-tumor activity in selected cancers, offering new treatment options for cancer patients with high unmet needs.
The study traces the evolutionary history of brown algae through genomic analysis, highlighting their role in sustaining coastal habitats and combating climate change. The research also identifies practical applications in aquaculture, biotechnology, and ecosystem restoration.
Researchers at Osaka Metropolitan University have discovered yeast cell wall-derived proteins that exhibit high emulsifying activity, comparable to commercial casein emulsifier. These easily released protein molecules could potentially replace emulsifiers derived from milk, eggs, and soybeans, reducing allergenic concerns.
BGI Genomics strengthens ties with Saudi Arabian partners to advance public health development through genomics technology. The company aims to apply its expertise in precision medicine to support Saudi Arabia's Vision 2030 goals.
Sage has acquired Mary Ann Liebert, Inc., expanding its portfolio of peer-reviewed journals in biotechnology and life sciences. The acquisition enhances reach and impact, ensuring high-quality science continues to make a difference.
Researchers have developed a biotechnological process to break down and remove the matrix from carbon fiber reinforced polymers (CFRPs), recovering valuable chemicals. Genetically modified fungi feed on benzoic acid produced during breakdown, yielding the compound OTA with potential medical applications.
Charles Shoemaker, a Tufts University professor, has been named Fellow of the National Academy of Inventors for his work on developing immunotherapeutics. His research focuses on creating antibody-based agents that can prevent and cure diseases, including those caused by viruses and bacteria.
The BioImage.IO Chatbot uses extensive language models and Retrieval-Augmented Generation (RAG) to provide real-time access to databases and minimize errors. It enables researchers to perform complex image analysis tasks in a simple manner, working directly with microscopes and laboratory equipment.
Scientists at the Swiss Federal Laboratories for Materials Science and Technology have successfully created luminous wood by combining fungal threads with hardwood. The process involves a two-stage enzymatic reaction that stimulates the production of luciferin, emitting green light from the treated wood.
Insilico Medicine has developed an innovative platform using generative AI to discover novel molecules. The company has nominated over 20 preclinical candidates and received IND clearance for 10 molecules.
Alex Zhavoronkov, Insilico Medicine's founder and CEO, was named Highly Cited Researchers of 2024. He has published over 40 peer-reviewed research papers, with a total H-index of 64, and led the development of Insilico's lead drug pipeline, ISM001-055.
Insilico Medicine has been selected by Fortune as one of the top AI innovators, leveraging its generative AI platform to develop novel drugs and treatments. The company's lead drug pipeline, ISM001-055, has shown promising results in Phase IIa trials, offering new hope for patients with idiopathic pulmonary fibrosis.
The new effort aims to rapidly transform academic breakthroughs into life-saving therapies for a range of medical conditions. Autobahn Labs will invest up to $5 million per selected project to support the development of new pharmaceuticals.
Researchers discovered a 10-amino-acid sequence, called the passport sequence, that facilitates efficient glycoprotein trafficking and enhances galactosylation and sialylation. This leads to improved protein stability and efficacy in biopharmaceuticals.
Researchers at Institute of Science Tokyo develop an innovative strategy to produce β- and γ-naphthocyclinones, challenging compounds that have potential for medical and biological applications. They successfully synthesize the molecules using a retrosynthetic analysis approach, achieving yields of over 70%.
Researchers developed a new AI-powered diagnostic system, FastGlioma, which reveals invisible cancerous tissue in brain tumor surgery. The technique may delay or prevent recurrence of high-grade tumors and improve patient survival.
Team Bath Heart, a team of students from the University of Bath, has won the second world Heart Hackathon title with their innovative artificial heart device. The team's prototype, which uses wireless charging and 3D printing, was praised for its novelty, progress, and presentation.
Researchers have developed a new CRISPR-Cas method to decipher the function of genetic variants that contribute to cancer. The approach creates tens of thousands of cells with different gene variants, allowing scientists to identify which variants make cancer cells resistant to standard drugs.
Scientists have designed bioluminescent proteins that can produce multiple colors of light for real-time imaging in cellular and animal models. These proteins are small, efficient, highly stable and can be used for non-invasive bioimaging, diagnostics, drug discovery and more.
Researchers from Osaka Metropolitan University have discovered a combination of green algae and yeast that enhances wastewater treatment efficiency. The mixture boosts the growth environment, uptake of ammonium and phosphate ions, making it an effective solution for wastewater treatment facilities.
Insilico Medicine CEO Alex Zhavoronkov to discuss AI business potential and economic growth at Fortune Global Forum 2024. The company has developed a generative AI-powered platform that utilizes deep learning techniques for novel target discovery and molecular structure generation.
Adipo Therapeutics' lead product ADPO-002NP shows promising results in increasing energy expenditure and improving insulin resistance by browning white adipose tissue. The company is now raising $8 million to move the treatment to first-in-human Phase I clinical trials.
Researchers led by Judith Su will develop a portable FLOWER sensing device for detecting zeptomolar concentrations of chemical warfare agents. The device has shown record-breaking sensitivity and could preserve the lives of active-duty service members.
Scientists have engineered synthetic genes that can assemble into complex biomaterials like nanoscale tubes, using a modular approach similar to building furniture. This breakthrough enables the creation of distinct materials that can spontaneously develop from a finite set of parts by rewiring the timing of molecular instructions.
Insilico Medicine has entered into a revolving loan facility of up to US$100 million with HSBC, enabling the company's global expansion and AI-driven innovation in biotechnology. The credit line will support Insilico's proprietary novel drug discovery pipeline and its end-to-end diversified AI platform, Pharma.AI.
Researchers from NARO and University of Tokyo successfully enhanced essential amino acids in BSF larvae through biotechnological approaches, boosting histidine and methionine levels by over 2.5 times. This development is expected to contribute to a stable food supply and promote sustainable food production.
Researchers synthesizing AI with biomarker analysis aim to detect early signs of aging and enable targeted interventions to delay disease. This approach has the potential to slow, prevent or reverse certain effects of aging.
Researchers from Texas A&M University synthesized research findings to improve medical devices and therapy success rates. The review emphasizes the need to understand macrophage cell behavior to develop targeted immunotherapy treatments.
The Graduate Assistance in Areas of National Need program will fund eight doctoral students at WPI, increasing the department's diversity and footprint. The fellowships will help create new career paths in life sciences.
The collaboration utilized Insilico's generative biology AI platform, Pharma.AI, to identify a novel lead for treating oncology diseases. The joint R&D team addressed the druggability challenge of highly novel targets using novel scaffolds generated by Chemistry42.
Twelve healthcare innovators have been shortlisted for the Global Healthcare Innovation Competition, with seven candidates selected for the 'Young Innovators' category. The competition aims to nurture transformative health solutions, providing a platform for innovators to develop and scale their ideas.
A new study found compositional and functional differences in the gut microbiota of Chinese long-living adults (over 90 years) compared to elderly adults (65–74 years). The researchers noted lower relative abundances of bacteria in certain genera, which may regulate biological processes like autophagy and telomere maintenance. These fi...
Dr. Wai Hong Lo, PhD, has been appointed as the new Editor-in-Chief of ASSAY and Drug Development Technologies, succeeding Dr. Bruce Melancon. Dr. Lo aims to enhance online accessibility, incorporate visuals, and increase social media engagement to reach a broader audience.
The Center for Genomic Diagnostics at the University of Illinois will develop sensitive and rapid biosensors to detect African swine fever virus. The grant aims to improve on-farm detection and surveillance, providing timely control measures.
A systematic review highlights common thoracic CT imaging findings in obese patients, including dynamic upper airway collapse and mosaic attenuation. The review also explores the potential link to fibrotic interstitial lung disease and discusses advancements in AI body morphometry for improved prognosis.
Researchers have discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in viruses and trap them. This discovery offers new avenues for antiviral therapies and could be used to devise strategies to combat these viruses.
The expert panel discussion sheds light on the best practices for injecting hyaluronic acid (HA) fillers in the infraorbital hollows. Top surgeons share their preferred fillers and techniques, providing valuable insights for treating undereye dark circles.
A new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START) has been developed to map the brain's intricate neuronal connections. The technique combines two advanced technologies to resolve cortical connectivity at the resolution of transcriptomic cell types, enabling the identification of distinct p...
A recent study published in iScience found that the length of time cells spend engaged in the repair process is also key to regulating regeneration in African killifish. The researchers discovered that skin cells launch a genetic program that primes the whole animal to prepare for a repair response, guiding repair cells to get to work.
Researchers at Rice University and Baylor College of Medicine are developing a new cell therapy platform to suppress inflammation and lung damage in ARDS patients. The platform uses engineered retinal pigment epithelial cells to locally produce anti-inflammatory agents, promising improved patient outcomes.
Researchers from Osaka Metropolitan University have developed a method to detect coronavirus spike proteins quickly and selectively using a light-induced immunoassay. The technique uses a milliwatt-level laser and can complete the entire process in under 5 minutes.
A systematic review of pharmacogenomics clinical decision support systems found that e-health tools can help integrate personalized medicine into everyday clinical practice. However, current implementation is limited, particularly in non-US healthcare systems.
Researchers at Osaka Metropolitan University used CRISPR/Cas9 to create a strain of Euglena that produces wax esters with shorter carbon chains, improving their cold flow and suitability as a biofuel feedstock. This breakthrough could potentially replace petroleum-based production of wax esters with biological sources.