Researchers from the University of Pennsylvania School of Veterinary Medicine and Children's Hospital of Philadelphia discovered a link between mitochondrial dysfunction in the blood-brain barrier and neuropsychiatric disease in patients with 22qDS. Treatment with bezafibrate, a cholesterol drug, may enhance BBB function and correct so...
Noncommutative metasurfaces enable diverse path entanglement by exploiting interaction between metasurfaces and entangled photons, expanding quantum information processing capabilities. The research paves the way for high-dimensional information encoding in quantum communications and parallel processing in quantum computing.
Researchers at Texas Biomed have developed a live attenuated vaccine that showed high efficacy in cells and animal models, protecting mice from lethal H5N1. The team identified potential treatment targets using human airway organoids, revealing how bird flu remodels airway cells and causes scar tissue to form.
Researchers found that ad hominem attacks are the most common way users confront perceived errors in comment sections, with a reliance on reputation-based insults. The study highlights the prevalence of this tactic and its implications for online discourse.
Researchers discovered a significant association between metabolic syndrome and an increased risk of Parkinson's disease. The study found that people with metabolic syndrome were about 40% more likely to develop the disease than those without it.
A recent University of Michigan-led study found that almost 10% of patients with sepsis who were previously healthy died within 90 days. These patients tended to have less organ failure and more COVID-19 related sepsis than those with underlying health conditions.
A new method called Causal Pivot detects hidden genetic drivers and subgroups patients by true biological causes of their illnesses. The tool paves the way for major advances in personalized genetic medicine by revealing genetic "routes" into diseases.
A plant-based diet is associated with reduced risk of multimorbidity caused by cancer and cardiometabolic diseases, regardless of age. Adults with higher adherence to a plant-based diet had a lower risk of multimorbidity compared to those with lower adherence.
Researchers at Tohoku University found that C60 fullerene can serve as an active catalytic site for CO2 electroreduction, improving the efficiency of reactions like hydrogen evolution and carbon dioxide reduction. The discovery opens new possibilities for designing efficient, metal-free catalysts to combat climate change.
KAUST researchers developed a mathematical model to predict fluted film behavior, which can inform design strategies for industries like food processing and pharmaceuticals. The study reveals complex shapes formed by the liquid as it drains from a tube.
Researchers at Stanford University developed a new delivery platform that allows drugs to be stored and delivered in much higher concentrations, enabling quicker and smoother injections. The new formulation method has been tested on three different proteins and reached concentrations exceeding 500 mg/mL.
Most Channel Islands foxes developed larger brains to adapt to survival demands in isolated conditions, defying the assumption that island animals have smaller brains. Brain size appeared to be shaped more by local habitat conditions than isolation or island size alone.
A new study projects the start of Amazon dieback as early as the 21st century under high-emission scenarios, triggered by extreme conditions and global warming levels above 1.5°C. The Amazon's natural water recycling system is weakened, leading to hotter and drier conditions that can no longer sustain dense vegetation.
Researchers have identified over 400 genes linked to accelerated aging, including subtypes such as cognitive decline and metabolic problems. The findings support the 'geroscience hypothesis' and suggest that treating aging itself may be key to preventing chronic illnesses.
Researchers successfully realized a stable, isolated quantum spin on an insulating magnesium oxide surface placed over a ferromagnetic iron substrate. The MgO/Fe(001) structure, widely used in spintronics, enables the formation of isolated spins due to its lack of conduction electrons.
A comprehensive review of pyridazinone derivatives reveals their therapeutic potential in treating multiple diseases. The compounds have shown anticancer, anti-inflammatory, antimicrobial, and neuroprotective properties, making them a valuable target for drug discovery.
Researchers have developed a hydrogel electrolyte that regulates the coordination environment of water molecules, enabling high-stability and flexibility in zinc-based devices. This breakthrough can lead to advanced energy storage solutions for extreme environments.
Experts argue that large language models require symbolic representation to excel in complex tasks, citing examples like the Pirahá people and Leibniz's calculus notation. The proposed approach, known as neuro-symbolic synthesis, combines statistical intuition with human-designed symbol systems for efficient reasoning.
A recent study found that digital divides between teachers and students in Illinois high schools undermine the effectiveness of state-mandated media literacy instruction. The researchers suggest that educators must consider students' lived experiences when teaching media literacy, given differing access to platforms and perceptions of ...
A recent study led by Washington State University found that carrying bacteria resistant to critical antibiotics is strongly linked to visiting health clinics or hospitals. Urban residents and households without trash pickup were also more likely to carry the bacteria.
Researchers from the University of Bath and University of Hong Kong found that additive advice bias is common in conversations, social media, and AI chatbots. This bias can leave people feeling more overwhelmed than helped, with well-intentioned tips piling on extra tasks.
Researchers at the University of British Columbia have demonstrated that electrochemically loading a solid metal target with deuterium fuel can increase fusion reaction rates by an average of 15%. The approach uses a room-temperature reactor and achieves this boost without generating heat, paving the way for clean energy generation.
Researchers introduce non-linearity to non-reciprocal interactions, resulting in dynamic and unpredictable system behavior. The system exhibits both run-and-chase dynamics and phase separation, with the roles of molecule species reversing dynamically, leading to chaos.
A team of researchers from Bonn investigated the influence of primary cilia dysfunction on adipocyte precursor cells in a mouse model. They found that overactivation of the Hedgehog signaling pathway causes abnormal development into connective tissue-like cells instead of white fat cells.
Researchers have deciphered the fly brain's process of filtering out visual information during sleep, creating a 'window' that allows strong stimuli to wake them up. This study may hold parallels for human brain function and could reveal a universal principle of sleep.
A study of over 40 research studies found that older adults often don't understand the risk of extreme heat and aren't prepared for long periods of hot weather. The researchers suggest that individuals themselves go through transformations as they age, which can affect their bodies' reactions to heat.
A new study published in Nature highlights the differences between hydrogen and carbon monoxide as reductants in oxide reduction, offering insights for more efficient and sustainable metal extraction. Hydrogen is found to facilitate faster and cleaner reaction kinetics, generating benign water vapor as a byproduct.
Researchers have developed a novel method to stimulate and mature human brain organoids using graphene, accelerating disease research and enabling brain-machine interfaces. The approach allows for safe, non-genetic, biocompatible stimulation of neural activity over days to weeks.
A recent study published in Proceedings of Royal Society B found minimal age-related inflammation among the Tsimane people in the Bolivian Amazon, who live a traditional hunter-farmer lifestyle. In contrast, the Moseten community, genetically similar to the Tsimane but with significant modernization, showed increased inflammation.
A high-salt diet triggers brain inflammation that drives up blood pressure, according to a new study. The research suggests the brain may be a missing link in certain forms of hypertension, traditionally attributed to the kidneys.
A new study from Columbia University Mailman School of Public Health finds that punitive laws are largely ineffective and may actually harm those they aim to protect. Prosocial laws, on the other hand, prioritize access to care and harm reduction, recognizing the complex nature of substance use.
A recent study published in Alzheimer's & Dementia found that women with Alzheimer's disease have a notable loss of unsaturated fats, such as omega-3 fatty acids, in their blood compared to healthy women. This suggests that lipids containing omega-3 fatty acids may play a crucial role in the risk for Alzheimer's between the sexes.
Researchers have designed protein qubits that can be produced by cells naturally, opening possibilities for precision measurements of tissues, single cells, or even individual molecules. These protein-based qubits can detect signals thousands of times stronger than existing quantum sensors.
A cross-sectional study of 42 countries found that drought conditions are associated with increased intimate partner violence risk. The study suggests a pressing need for initiatives to prevent domestic violence in response to climate change.
A new study reveals that endometriosis can lead to lower blood pressure responses in women due to altered autonomic nervous system functions. This finding may have significant implications for diagnosis and treatment of the condition.
Researchers from RMIT University have developed a new wastewater treatment system that targets all fat types, including hard-to-remove emulsified fats, and achieves up to 98% fat removal rates in commercial kitchen wastewater. The system combines a redesigned grease interceptor with smart chemical treatment.
A new study by University of Nottingham scientists assesses biodiversity credit suppliers against six integrity criteria, finding notable weaknesses in verifiable outcomes and risk disclosure. The authors advocate for transparent governance and harmonized data collection protocols to ensure credibility and impact.
Scientists have discovered a new type of metal oxide that can breathe oxygen at relatively low temperatures. This unique ability makes it ideal for real-world applications in clean energy technologies, including fuel cells and energy-saving windows.
The study found a significant reduction in mortality while waiting for a new heart, despite increased waiting times. Technological advances and improved healthcare practices are credited with the improvements.
Researchers found a connection between high TMAO levels and faster rates of aneurysm expansion, as well as greater risk for needing surgery. Targeting TMAO levels may help prevent and treat aneurysmal disease beyond surgery.
A study analyzing acute and chronic stress on rat brains reveals distinct effects on mental health. Acute stress triggers anxiety-like behaviors, primarily in males, whereas chronic stress is linked to depressive symptoms.
A wearable robot has been upgraded to provide personalized assistance to ALS and stroke patients. The device uses machine learning and a physics-based model to adapt to an individual user's movements, offering more nuanced help with daily tasks.
A novel AI model developed by the Dresden research team simultaneously detects multiple genetic alterations directly from routinely stained histological colon cancer tissue sections. The model recognized shared visual patterns rather than independently identifying individual genetic alterations.
Paul Cherukuri becomes UVA's first Chief Innovation Officer, leading the next phase of a university-wide innovation ecosystem. He aims to foster cross-school collaboration, empower faculty and students to translate ideas into impact, and expand partnerships with industry and government.
The new book provides real-world strategies for arts leaders to navigate financial instability, advocate for equity and inclusion, and implement sustainable business models. With a focus on case study Bethesda's Imagination Stage, the authors examine leadership traits that drive innovation and long-term viability in nonprofit theaters.
A new study published in Molecular Nutrition and Food Research found that red meat consumption causes an imbalance of bacteria in the intestinal microbiota, leading to exacerbated colonic inflammation. The diets resulted in a decrease in beneficial bacterial strains and an increase in pro-inflammatory cells.
Korea Research Institute of Standards and Science (KRISS) has successfully localized core Radar Stealth technologies through indigenous development. The institute developed a Frequency Selective Surface design software and an electromagnetic wave evaluation system for radomes, laying the foundation for stealth weapon systems in Korea.
Researchers at Penn State developed a wearable sensor that accurately measures chloride ion levels in sweat, enabling early diagnosis of cystic fibrosis. The sensor uses multiple types of hydrogel to track small fluctuations in chloride ion levels, providing real-time information on an individual's health.
Researchers at UC Berkeley developed an AI-powered training method called Human-in-the-Loop Sample Efficient Robotic Reinforcement Learning (HiL-SERL) that enables robots to perform complicated tasks with precision and speed. With human feedback, robots learn from demonstrations and real-world attempts, achieving a 100% success rate in...
The TReNDS Center has received two new NIH-funded R01 grants aimed at tackling Alzheimer's disease progression and advancing multimodal brain imaging techniques in neuropsychiatric disorders. The center will develop flexible models to link data and uncover complex patterns in neuroimaging and genomics.
A new study suggests that high-energy, less acoustic songs evoke memories of amusement and excitement, while lower-energy, more acoustic songs evoke memories of calmness, romance, and sadness. The researchers found that specific auditory features of music can predict certain qualities of autobiographical memories.
The Icahn School of Medicine at Mount Sinai has been awarded a five-year, $64 million grant to establish the Advancing the Science of Palliative Care Research Across the Lifespan (ASCENT) consortium. The consortium will support high-quality research for enhancing care for people living with serious illness and their caregivers.
The Leopoldina and Max Planck Society have published a database of over 16,000 victims of coerced medical research under National Socialism, providing a platform for remembrance and research. The database connects individuals to primary and secondary sources, enabling further studies and analyses.
A groundbreaking study has identified key genes and compounds in Rhizoma Coptidis that may modulate cell cycle dysfunction in tendinopathy. The research highlights the potential of traditional Chinese medicine in modern therapeutics, with a focus on experimental validation in animal models and clinical trials.
Researchers at the University of Chicago discovered that random fluctuations in gene expression enable certain cells to express genes from other tissues, promoting immune system training and tissue repair. This 'epigenetic noise' can also contribute to cancer development by allowing cancer cells to access a broader range of genes.
Researchers develop a novel process to convert polyethylene and polypropylene into valuable olefins, producing fewer unwanted byproducts. The method uses inexpensive base-metal catalysts, operates under mild conditions, and achieves high yields of propylene and isobutylene.
Research in Business Strategy and the Environment reveals stronger LGBTQ+ inclusion correlates with higher environmental scores and greater renewable energy consumption among U.S. firms. This relationship is partially mediated by environmental innovation, suggesting inclusive workplace practices enhance environmental outcomes.
A recent study found that wolf hunting has a limited effect on reducing livestock losses, with an average reduction of 2% in predation rates. However, the impact of hunting on lethal removals, which are expensive operations targeting specific wolves, is negligible.
Prof. Oron Shagrir, a seasoned academic leader, has been elected as the new Rector of the Hebrew University of Jerusalem. He will assume office in October 2025, succeeding Prof. Tamir Sheafer, and is expected to further enhance excellence in teaching and research.
A new Zika virus vaccine developed by Brazilian researchers has been shown to be safe and effective in tests with mice, inducing an immune response and protecting against brain and testicular damage. The vaccine uses a technology known as 'virus-like particles' (VLPs) without genetic material from the pathogen.