A new AI-based model identifies four central state dimensions that better capture the progression of MS, including physical disability and brain damage. The findings could fundamentally change diagnosis and treatment for MS patients.
A team of materials scientists at Rice University developed a new way to grow ultrathin semiconductors directly onto electronic components using chemical vapor deposition. The breakthrough technique eliminates the fragile manufacturing step, potentially speeding up development of next-generation electronics and computing.
Two new studies from Karolinska Institutet investigate how somatic mutations in muscles and blood vessels affect ageing. The results show that such mutations can reduce muscle strength and accelerate blood vessel ageing.
Catherine Whittington, a WPI researcher, has received a CAREER Award to develop laboratory models for the study of fibrosis in pancreas, skin, and uterine fibroids. The models will help researchers better understand factors at the cellular level that lead to fibrosis and how interventions can interrupt or reverse it.
A simple method for preparing diverse microhelices with high mechanical properties and excellent biocompatibility has been reported. The researchers developed a two-stage coaxial microfluidic device to control the structure of microhelices, enabling the creation of PEGDA microhelices with excellent motion performance in human blood.
The Lehigh K-12 Computer Science STEELS Toolkit provides flexible, free enrichment activities for elementary and secondary classrooms. The toolkit aligns with Pennsylvania's STEELS framework and aims to foster integrated literacy in science, technology, engineering, and sustainability.
A cohort study found a higher prevalence of eating disorders among adolescents from lower socioeconomic backgrounds. The study suggests that reducing population-level socioeconomic inequalities may aid in preventing eating disorders.
Researchers found a strong correlation between industrial pollution exposure during pregnancy and the risk of intellectual disabilities in grandchildren. A study using Utah Population Database data revealed that grandmothers' prenatal exposures can increase the risk of intellectual disabilities in their grandchildren's children.
A new study creates a single-cell map of epigenomic regulation in human fat tissue, revealing how genetic risk factors contribute to abdominal obesity. The research identifies key regulatory regions in fat cells where obesity-linked variants reside, offering new clues to the genetic and epigenetic regulation of body fat.
New research warns of impending abrupt Antarctic changes that could have devastating consequences for the region's wildlife, ocean ecosystems, and global climate. The West Antarctic Ice Sheet is at risk of collapse, leading to catastrophic sea level rise and warming in Australia and beyond.
The updated fourth edition of the Laboratory Guide for Identification of Plant Pathogenic Bacteria provides simplified identification methods and detailed protocols. The comprehensive volume covers conventional and cutting-edge methods, including molecular, serological, biochemical assays, to accurately identify bacterial plant pathogens.
A study by UKCEH found that ash dieback results in significant greenhouse gas emissions due to soil carbon losses. The research estimated 5.8 million tonnes of CO2 emissions over five years, equivalent to half the amount removed by broadleaf woodlands annually.
Research follows 8,795 Wisconsin children from birth to third grade, finding early foster care placement linked to improved reading skills and lower absenteeism. However, findings also reveal racial disparities, with limited benefits for white children, emphasizing the need for targeted support and resources.
MIST uses a hierarchical, rules-based classification system grounded in verified mineral formulas from the RRUFF mineral database. It accurately identifies hundreds of different mineral species from their chemical composition, even accounting for natural imperfections and vacancies found in real minerals.
The American Association of Blood Banks (AABB) has updated its transfusion standards to recommend giving more-frequent blood transfusions to patients suffering from myocardial infarction, particularly those with low hemoglobin levels. This new guideline aims to prevent recurrent heart attacks and deaths among anemic patients.
A video study of wild spectral bats reveals social greetings, food provision, and cooperative foraging behaviors. The bats were found to exhibit gentle and cooperative behavior, recognizing researchers and forming tight cuddle-balls while roosting.
A new online assessment tool, developed by Penn State, assists veteran-serving organizations in identifying individualized risks and providing targeted support. The tool, called the Veteran Transition Screener (VTS), uses predictive models to match a veteran's demographic profile with risk factors linked to poor transition outcomes.
Astronomers discover stripped-down supernova with unusual chemical signature, providing evidence for the layered structure of stellar giants and unprecedented glimpse into a massive star's interior. The study reveals that stars can lose extensive material before exploding, challenging current theories on stellar evolution.
Researchers found that corn's root traits evolved in response to changing nitrogen availability and water levels, with fewer nodal roots and development of multiseriate cortical sclerenchyma helping the crop adapt. These adaptations enabled corn to thrive under varying environmental conditions, including a warming climate.
Researchers developed a machine learning model that accounts for biological variability to identify optimal formulations for serum-free culture media. The model achieved approximately 1.6-fold higher cell density compared to commercially available products.
Researchers developed a dynamic nomogram to predict long-term survival in patients with brain abscess, identifying key predictors such as age, Karnofsky performance status, and hemoculture results. The model offers an interactive tool for individualized risk assessment, facilitating better treatment decisions and improving outcomes.
A recent study co-authored by UCF Assistant Professor of Biology Robert Fitak reveals that the 1990s translocation of Texas pumas improved the Florida panther's genetic health while preserving its unique ancestry. The study found increased genetic variation, retention of unique traits, and a decrease in harmful mutations.
Lucia Strader's lab at Salk will explore how plants sense and integrate environmental cues to shape their growth and development. Her work aims to advance fundamental understanding of plant biology and design more resilient crop varieties.
Researchers found traditional methods poorly suited for invertebrates due to limited data and rare species challenges. New statistical methods suggest combining data across species, assessing similar species, or targeting extinction risk assessment to communities and habitats.
A team of scientists observed the earliest steps of ultrafast charge transfer in a complex dye molecule, with high-frequency vibrations playing a central role. The experiments showed that these vibrations initiate charge transport, while processes in the surrounding solvent begin only at a later stage.
Researchers have found that hyperactivity in a specific brain region can drive behaviors associated with autism spectrum disorder. They reversed symptoms such as seizures, sensory hypersensitivity and repetitive behaviors by suppressing this area of the brain using epilepsy drugs.
A new University of Georgia study finds that meaningful conversations can form connections on first dates, regardless of the setting. Participants reported feeling close or romantically attracted to others despite not being in an appealing environment.
Dwarf Channel Island foxes (Urocyon littoralis) have larger brains than their mainland gray fox counterparts, contradicting the notion of island-specific evolutionary pressures leading to reduced brain size. This finding suggests little evidence of domestication in these isolated California islands.
Researchers from Kessler Foundation will share insights on spinal cord injury recovery, technological innovation, and caregiver support. The conference highlights the Foundation's leadership in rehabilitation science and commitment to advancing outcomes for individuals with SCI.
Southwest Research Institute (SwRI) has opened its first facility outside of Texas in Warner Robins, Georgia, with a 33,000-square-foot, $18.5 million building supporting Air Force and national defense advancements. The new structure houses offices, conference rooms, and laboratories for developing advanced aerospace technology and ele...
Researchers at Kyoto University discovered that streamers of gas can feed young stars, potentially leading to the rapid formation of high-mass stars. The team used ALMA to observe a system with two streamers, which carried enough matter to quench feedback effects from the central star.
Researchers developed a sustainable solution to help tackle honeybee decline by creating an engineered food supplement. The new feed, designed to provide essential compounds found in plant pollen, significantly enhances colony reproduction.
The asymmetric MXene-graphene bilayer aerogel delivers over 100 dB EMI shielding, 115 °C solar-thermal heating, dynamic IR camouflage, thermal insulation and oil absorption, all without external power beyond sunlight or a pulse.
Ancient Sumerian society harnessed tidal hydrology to irrigate crops, enabling high-yield agriculture without large-scale infrastructure. The research suggests that the early communities' dependence on dependable hydrology drove societal response and defined the golden age of Sumer.
A new pilot study from University Hospitals Cleveland Medical Center found that music therapy improved pain after pancreatic surgery, supporting its feasibility and acceptability. The study also suggests continued use of music-assisted relaxation recordings over the course of hospitalization to further reduce post-operative symptoms.
Research led by the University of Utah found that industrial private land has nearly one-and-a-half times higher odds of high-severity wildfire compared to publicly owned forests. Reducing tree density can mitigate megafire risk even in extreme weather conditions.
The new book, Monster Transformation, argues that employees are key to overcoming transformational hurdles. By uncovering unique competencies and empowering them, organizations can break through challenges and succeed in a rapidly evolving space. The book offers a story-driven approach to meeting the needs of the current technological ...
A comprehensive guide to improve plant imaging workflows, addressing unique challenges such as waxy cuticles and autofluorescence. The resource provides a unified workflow framework, focuses on reproducibility and reporting standards, and offers practical illustrations and tools.
Researchers at TU Wien developed a novel microscopy method that allows for gentle imaging of sensitive biological structures and quantum particles. The new technique stores light in an optical resonator where the sample is also located, providing clearer signals than other methods.
A study by UC San Diego researchers reveals that paying enforcers to punish makes people less likely to cooperate with others, leading to social norms breaking down. Cooperation declined after punishment was introduced, even when punishment targeted selfish behavior.
Researchers found that cancer cells break down nerve protective covers, triggering chronic inflammation and immune exhaustion, making treatment resistant. Targeting the nerve injury pathway can reverse this resistance and improve treatment response.
A multicenter study in China found that patients with liver cirrhosis were prone to community-acquired pneumonia and spontaneous bacterial peritonitis, with Klebsiella pneumoniae and MDR organisms being major concerns. The study highlights the need for region-specific strategies to improve outcomes for this vulnerable population.
The study combines decision making and machine learning to improve robot learning for water analysis. The Random Forest Classifier achieved an accuracy of 69% which improved to 73% after applying Synthetic Minority Over-sampling Technique (SMOTE) and tuning hyperparameters. The robotic system can detect, analyze, and distinguish drinki...
A recent study published in Nature Communications provides a comprehensive characterization of Large Cell Neuroendocrine Carcinoma (LCNEC), a rare and aggressive type of lung cancer. The research team analyzed data from 590 patients and found that LCNEC shares features with other types of lung cancer, yet has distinct aspects. They ide...
A research team has created a database of predicted chemical structures for improved detection of designer drugs. The Drugs of Abuse Metabolite Database (DAMD) uses computer modeling to identify potential metabolites and mass spectra, which can help law enforcement detect new psychoactive substances.
BioPACIFIC MIP accelerates biomaterials innovation with autonomous experimentation and robotics, supporting over 130 research projects across the US. The platform aims to connect fundamental research with industry needs, fostering paradigm shifts in new material discovery.
Researchers at UCL discovered that blocking brain damage triggered by glioblastomas can slow cancer growth and maintain normal brain function. The study found that early-stage tumours damaged axons, accelerating tumor growth, but deactivating SARM1 slowed tumor progression.
Researchers from Tohoku University have discovered a new material that can conduct both protons and electrons efficiently at intermediate temperatures. The material, titanium dioxide doped with niobium, enhances proton conductivity by up to 10 times, making it suitable for next-generation fuel cells and hydrogen separation membranes.
The Global Virus Network's inaugural 'Global Guardians: Youth for Pandemic Preparedness' summer camp engaged high school students in virology, pandemic response, and public health careers. Students participated in hands-on activities, laboratory tours, and collaborative group exercises, guided by internationally renowned experts.
The XRISM observation revealed clear absorption lines from highly ionized iron at the system's faintest X-ray phase, providing a rare glimpse into hot gas structure and motion. The results suggest that even in low-luminosity states, highly ionized gas can be present around black holes.
Scientists at Penn State developed a new method to predict superconducting materials using density functional theory and zentropy theory, potentially leading to discovery of new superconductors at higher temperatures. The approach successfully predicted signs of superconductivity in conventional and high-temperature superconductors.
Two former Department of Justice scientists argue for transformative crime prevention research prioritizing social justice alongside public safety. They emphasize the need for research incorporating community perspectives and collaborative approaches to prevent harm and promote justice.
Research shows that cardiovascular health scores among older adults with high blood pressure, stroke, or heart failure decreased significantly. The study analyzed data from the US National Health and Nutrition Examination Survey, finding that physical activity and blood pressure scores were low for those with cardiovascular disease.
A study predicts that climate change will spread Dengue fever through Western Europe as the Asian tiger mosquito's habitat expands. Major cities like London and Paris are expected to become suitable for the mosquito, posing a significant threat to public health.
Researchers at the University of Waterloo have developed a novel method using modified M13 bacteria to deliver targeted gene therapies for genetic disorders. This approach shows promise as a cost-effective alternative to current methods, which can be expensive and trigger toxic side effects.
A study identified eight additional foods frequently involved in food-induced anaphylaxis, including goat's and sheep's milk, buckwheat, and pine nut. The research proposes that these foods be considered for inclusion on the European mandatory labelling of foods list due to their frequency, severity, and potential for hidden exposure.
Researchers identified bile acid metabolites as potential biomarkers for diagnosing and predicting drug-induced liver injury (DILI). Chenodeoxycholic acid and deoxycholic acid were found to distinguish DILI patients from healthy individuals, exhibiting predictive potential for chronicity.
Researchers have found that stylolites in limestone rock samples disrupt sound wave propagation, particularly affecting secondary waves that form due to scattering. This discovery has implications for monitoring hydraulic fracture propagation in rock samples containing stylolites.
Researchers at Mizzou have identified two tiny molecules, agmatine and thiamine, that may serve as biomarkers for early detection of glaucoma. These metabolites could also be used to develop new neuroprotective treatments, aiming to slow or stop the progression of vision loss.
A University of Queensland study suggests the antivenom given to people bitten by Eastern Brown Snakes may not be as effective as it could be due to geographic variations in venom. The research found that venom from southern Australia has a strong, stable blood clot, while northern populations trigger fragile but rapid clots.