Articles tagged with Biotechnology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers use SCP-Nano to analyze distribution of extremely low doses of nanocarriers throughout the mouse body, visualizing each cell that has taken them up. The platform identifies unwanted accumulation in organs like the heart and liver, paving the way for safer mRNA therapeutics.
Scientists at the University of Stuttgart have developed a new tool for synthetic biology using DNA nanorobots that can alter artificial cells. These nanorobots enable the formation of transport channels in synthetic cell membranes, allowing large molecules to pass through and facilitating the transportation of therapeutic proteins.
The Menarini Group and Insilico Medicine have entered into an exclusive licensing agreement for a preclinical small molecule targeting solid tumor cancers. The asset has demonstrated broad anti-tumor activity in selected cancers, offering new treatment options for cancer patients with high unmet needs.
The study traces the evolutionary history of brown algae through genomic analysis, highlighting their role in sustaining coastal habitats and combating climate change. The research also identifies practical applications in aquaculture, biotechnology, and ecosystem restoration.
Researchers at Osaka Metropolitan University have discovered yeast cell wall-derived proteins that exhibit high emulsifying activity, comparable to commercial casein emulsifier. These easily released protein molecules could potentially replace emulsifiers derived from milk, eggs, and soybeans, reducing allergenic concerns.
BGI Genomics strengthens ties with Saudi Arabian partners to advance public health development through genomics technology. The company aims to apply its expertise in precision medicine to support Saudi Arabia's Vision 2030 goals.
Sage has acquired Mary Ann Liebert, Inc., expanding its portfolio of peer-reviewed journals in biotechnology and life sciences. The acquisition enhances reach and impact, ensuring high-quality science continues to make a difference.
Researchers have developed a biotechnological process to break down and remove the matrix from carbon fiber reinforced polymers (CFRPs), recovering valuable chemicals. Genetically modified fungi feed on benzoic acid produced during breakdown, yielding the compound OTA with potential medical applications.
Charles Shoemaker, a Tufts University professor, has been named Fellow of the National Academy of Inventors for his work on developing immunotherapeutics. His research focuses on creating antibody-based agents that can prevent and cure diseases, including those caused by viruses and bacteria.
The BioImage.IO Chatbot uses extensive language models and Retrieval-Augmented Generation (RAG) to provide real-time access to databases and minimize errors. It enables researchers to perform complex image analysis tasks in a simple manner, working directly with microscopes and laboratory equipment.
Scientists at the Swiss Federal Laboratories for Materials Science and Technology have successfully created luminous wood by combining fungal threads with hardwood. The process involves a two-stage enzymatic reaction that stimulates the production of luciferin, emitting green light from the treated wood.
Insilico Medicine has developed an innovative platform using generative AI to discover novel molecules. The company has nominated over 20 preclinical candidates and received IND clearance for 10 molecules.
Alex Zhavoronkov, Insilico Medicine's founder and CEO, was named Highly Cited Researchers of 2024. He has published over 40 peer-reviewed research papers, with a total H-index of 64, and led the development of Insilico's lead drug pipeline, ISM001-055.
Insilico Medicine has been selected by Fortune as one of the top AI innovators, leveraging its generative AI platform to develop novel drugs and treatments. The company's lead drug pipeline, ISM001-055, has shown promising results in Phase IIa trials, offering new hope for patients with idiopathic pulmonary fibrosis.
The new effort aims to rapidly transform academic breakthroughs into life-saving therapies for a range of medical conditions. Autobahn Labs will invest up to $5 million per selected project to support the development of new pharmaceuticals.
Researchers discovered a 10-amino-acid sequence, called the passport sequence, that facilitates efficient glycoprotein trafficking and enhances galactosylation and sialylation. This leads to improved protein stability and efficacy in biopharmaceuticals.
Researchers at Institute of Science Tokyo develop an innovative strategy to produce β- and γ-naphthocyclinones, challenging compounds that have potential for medical and biological applications. They successfully synthesize the molecules using a retrosynthetic analysis approach, achieving yields of over 70%.
Researchers developed a new AI-powered diagnostic system, FastGlioma, which reveals invisible cancerous tissue in brain tumor surgery. The technique may delay or prevent recurrence of high-grade tumors and improve patient survival.
Team Bath Heart, a team of students from the University of Bath, has won the second world Heart Hackathon title with their innovative artificial heart device. The team's prototype, which uses wireless charging and 3D printing, was praised for its novelty, progress, and presentation.
Researchers have developed a new CRISPR-Cas method to decipher the function of genetic variants that contribute to cancer. The approach creates tens of thousands of cells with different gene variants, allowing scientists to identify which variants make cancer cells resistant to standard drugs.
Scientists have designed bioluminescent proteins that can produce multiple colors of light for real-time imaging in cellular and animal models. These proteins are small, efficient, highly stable and can be used for non-invasive bioimaging, diagnostics, drug discovery and more.
Researchers from Osaka Metropolitan University have discovered a combination of green algae and yeast that enhances wastewater treatment efficiency. The mixture boosts the growth environment, uptake of ammonium and phosphate ions, making it an effective solution for wastewater treatment facilities.
Insilico Medicine CEO Alex Zhavoronkov to discuss AI business potential and economic growth at Fortune Global Forum 2024. The company has developed a generative AI-powered platform that utilizes deep learning techniques for novel target discovery and molecular structure generation.
Adipo Therapeutics' lead product ADPO-002NP shows promising results in increasing energy expenditure and improving insulin resistance by browning white adipose tissue. The company is now raising $8 million to move the treatment to first-in-human Phase I clinical trials.
Researchers led by Judith Su will develop a portable FLOWER sensing device for detecting zeptomolar concentrations of chemical warfare agents. The device has shown record-breaking sensitivity and could preserve the lives of active-duty service members.
Scientists have engineered synthetic genes that can assemble into complex biomaterials like nanoscale tubes, using a modular approach similar to building furniture. This breakthrough enables the creation of distinct materials that can spontaneously develop from a finite set of parts by rewiring the timing of molecular instructions.
Insilico Medicine has entered into a revolving loan facility of up to US$100 million with HSBC, enabling the company's global expansion and AI-driven innovation in biotechnology. The credit line will support Insilico's proprietary novel drug discovery pipeline and its end-to-end diversified AI platform, Pharma.AI.
Researchers from NARO and University of Tokyo successfully enhanced essential amino acids in BSF larvae through biotechnological approaches, boosting histidine and methionine levels by over 2.5 times. This development is expected to contribute to a stable food supply and promote sustainable food production.
Researchers synthesizing AI with biomarker analysis aim to detect early signs of aging and enable targeted interventions to delay disease. This approach has the potential to slow, prevent or reverse certain effects of aging.
Researchers from Texas A&M University synthesized research findings to improve medical devices and therapy success rates. The review emphasizes the need to understand macrophage cell behavior to develop targeted immunotherapy treatments.
The Graduate Assistance in Areas of National Need program will fund eight doctoral students at WPI, increasing the department's diversity and footprint. The fellowships will help create new career paths in life sciences.
The collaboration utilized Insilico's generative biology AI platform, Pharma.AI, to identify a novel lead for treating oncology diseases. The joint R&D team addressed the druggability challenge of highly novel targets using novel scaffolds generated by Chemistry42.
Twelve healthcare innovators have been shortlisted for the Global Healthcare Innovation Competition, with seven candidates selected for the 'Young Innovators' category. The competition aims to nurture transformative health solutions, providing a platform for innovators to develop and scale their ideas.
A new study found compositional and functional differences in the gut microbiota of Chinese long-living adults (over 90 years) compared to elderly adults (65–74 years). The researchers noted lower relative abundances of bacteria in certain genera, which may regulate biological processes like autophagy and telomere maintenance. These fi...
Dr. Wai Hong Lo, PhD, has been appointed as the new Editor-in-Chief of ASSAY and Drug Development Technologies, succeeding Dr. Bruce Melancon. Dr. Lo aims to enhance online accessibility, incorporate visuals, and increase social media engagement to reach a broader audience.
The Center for Genomic Diagnostics at the University of Illinois will develop sensitive and rapid biosensors to detect African swine fever virus. The grant aims to improve on-farm detection and surveillance, providing timely control measures.
A systematic review highlights common thoracic CT imaging findings in obese patients, including dynamic upper airway collapse and mosaic attenuation. The review also explores the potential link to fibrotic interstitial lung disease and discusses advancements in AI body morphometry for improved prognosis.
Researchers have discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in viruses and trap them. This discovery offers new avenues for antiviral therapies and could be used to devise strategies to combat these viruses.
The expert panel discussion sheds light on the best practices for injecting hyaluronic acid (HA) fillers in the infraorbital hollows. Top surgeons share their preferred fillers and techniques, providing valuable insights for treating undereye dark circles.
A new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START) has been developed to map the brain's intricate neuronal connections. The technique combines two advanced technologies to resolve cortical connectivity at the resolution of transcriptomic cell types, enabling the identification of distinct p...
A recent study published in iScience found that the length of time cells spend engaged in the repair process is also key to regulating regeneration in African killifish. The researchers discovered that skin cells launch a genetic program that primes the whole animal to prepare for a repair response, guiding repair cells to get to work.
Researchers from Osaka Metropolitan University have developed a method to detect coronavirus spike proteins quickly and selectively using a light-induced immunoassay. The technique uses a milliwatt-level laser and can complete the entire process in under 5 minutes.
Researchers at Rice University and Baylor College of Medicine are developing a new cell therapy platform to suppress inflammation and lung damage in ARDS patients. The platform uses engineered retinal pigment epithelial cells to locally produce anti-inflammatory agents, promising improved patient outcomes.
A systematic review of pharmacogenomics clinical decision support systems found that e-health tools can help integrate personalized medicine into everyday clinical practice. However, current implementation is limited, particularly in non-US healthcare systems.
Researchers at Osaka Metropolitan University used CRISPR/Cas9 to create a strain of Euglena that produces wax esters with shorter carbon chains, improving their cold flow and suitability as a biofuel feedstock. This breakthrough could potentially replace petroleum-based production of wax esters with biological sources.
Researchers have successfully multiplied beta-carotene levels in lettuce leaves by up to 30 times using biotechnological techniques and high light intensity. The discovery represents a significant advance for improving nutrition through biofortification of leafy greens like lettuce, spinach, and chard.
A research team at Hiroshima University developed an analytical pipeline to identify unexploited genes associated with Parkinson's disease and oxidative stress. The study revealed two novel candidate genes, NUPR1 and UHRF2, which were absent from current gene-disease associations databases.
The University of Kentucky has been awarded a six-year, $18 million NSF grant to establish the NSF ESCAPE center for assessing pathogen emergence. The center will focus on environmental surveillance using social science, engineering, bioinformatics, and risk modeling to predict and prevent pandemics.
Researchers found that Prunin laurate, derived from citrus and coconut biomass, inhibits bacterial growth in periodontal pathogen Porphyromonas gingivalis. The compound is tasteless and hypoallergenic, making it a potential inexpensive antimicrobial solution for preventing oral inflammation.
Researchers have developed a novel, more selective inhibitor of the human immunoproteasome using a bacterially derived natural product. The new compound targets autoimmune diseases without disrupting other cellular mechanisms.
Researchers have successfully produced biodegradable plastics with ring-like structures, which could be used for biomedical applications such as drug delivery. The bacteria-based production method has the potential to replace petroleum-based plastics, offering a sustainable alternative.
A new research project aims to create a highly effective and selective biological herbicide targeting Palmer amaranth. The researchers will use synthetic biology techniques to develop RNA molecules known as Ribozymes that can influence specific gene expression, eliminating the weed through a specific infection.
Researchers developed a new brain-computer interface that translates brain signals into speech with up to 97% accuracy, enabling a man with amyotrophic lateral sclerosis (ALS) to communicate with friends and family. The system was tested in real-time conversations with continuous updates, achieving high word accuracy rates.
Researchers discovered that the iron nitrogenase can convert CO2 into methane and formic acid, making it a promising starting point for developing novel CO2 reductases. The enzyme's low selectivity for CO2 also suggests its potential for widespread use in nature.
Researchers at Heidelberg University have developed a process for producing biologically active peptide boronic acids, which could be used to induce an immune reaction against tumor cells. The new substances also show promise for targeted release of active compounds in the body.
Scientists at Macquarie University propose using genetically engineered black soldier flies to transform waste management and sustainable biomanufacturing. The flies can consume large volumes of waste quickly, producing valuable industrial inputs such as enzymes and lipids.
A study found that microwaves contain a unique microbial community, comprising 747 different genera, which resembles those on solar panels and kitchen surfaces. The diversity of the microbiome varies between single-household kitchens, shared domestic spaces, and laboratory microwaves.
The game illustrates how lifestyle choices, such as eating vegetables and drinking alcohol, impact the human microbiome. Researchers developed the game to provide a comprehensive overview of the microbiome in a fun and accessible way.
A new study found that meeting partners online is positively linked to relationship success among those who have social media presence on their relationships. However, the link was absent among individuals without this social media presence, particularly in marital relationships.
Liheng Cai, a UVA engineering professor, has received a $1.9 million NIH grant to create advanced biomaterials that can be used to repair living tissues and build organ structures. His lab aims to develop polymers that mimic human biology and integrate healthy cells into the human body.