Articles tagged with Biotechnology
The study reveals that PFESA exposure significantly increases antibiotic resistance gene proliferation by restructuring extracellular polymeric substances and triggering cellular stress responses. This enhances the persistence of resistant taxa in microbial communities, posing a risk to human health.
Researchers at UW Medicine Institute for Protein Design and Skape Bio used AI methods to create on-demand molecules that can toggle GPCRs. The approach enables precise control of GPCR signaling in cells, offering new insights into bodily functions and potential medicines for diseases.
Researchers found that increasing ADAR2 expression in osteosarcoma cells forces them to differentiate, slowing growth and invasive capacity. The treated cells began producing mineralized matrix, a hallmark of mature bone tissue. In mice, ADAR2-restored tumors were smaller and less invasive.
Odylia Therapeutics is advancing a gene therapy treatment for Usher Syndrome Type 1C (USH1C)-associated vision loss, a rare autosomal recessive disorder. The grant will support the development of an investigational USH1C gene therapy designed to restore or preserve vision.
Recent advancements in animal models, organoid models, and bioengineered organoids have provided new tools for studying primary sclerosing cholangitis. These models replicate the effects of bile retention and inflammation, enabling studies of disease mechanisms, drug screening, and preclinical evaluation.
The University of Utah is launching a groundbreaking testbed, SMART, to accelerate the development of breakthrough technologies in rare earth elements. The initiative aims to strengthen domestic supply chains and address the nation's growing need for critical minerals.
Osaka Metropolitan University researchers developed a light-driven method to rapidly collect microscopic targets, outperforming traditional techniques. The technique concentrates bacteria between 1000-10,000 times faster than existing approaches, paving the way for early disease detection and analysis of nanoparticles.
Researchers at Stanford University have developed a new approach called MIDAS, which enables the creation and testing of proteins in just 24 hours. This eliminates the need for labor-intensive cloning processes, allowing for faster and more cost-effective evaluation of protein variants.
Researchers develop automated plasma-bubble technology that intensifies cold plasma-liquid interaction to transform industrial wastewater into a reusable fertigation medium. The technology fixes vital bioavailable nitrogen in wastewater, reducing organic loads and suspended particles while increasing plant growth rates.
The SKKU research team developed DeepTYLCV, an experimentally validated AI model predicting TYLCV virulence. The model achieved 100% concordance with experimental observations, offering a powerful tool for early viral surveillance and resistance breeding programs.
Research suggests that jellyfish bycatch can provide high-quality collagen without compromising quality. This circular bioeconomy solution offers new economic opportunities for small-scale fisheries while reducing waste. The collaboration with fishers revealed a willingness to participate in recycling jellyfish bycatch, but also highli...
Bionema Group Ltd, a Swansea University spin-out, has received the second King's Award for Enterprise: Sustainable Development. The company develops biological pest control and sustainable agriculture technologies, providing environmentally sustainable alternatives to synthetic pesticides.
Researchers engineered an anaerobic bacterium to target periodontitis, reducing key pathogens and promoting tissue repair. The treatment lowered oxidative stress and restored the oral microbiome, offering a potential therapeutic solution for inflammatory diseases.
An international team, led by Göttingen University, investigates how molecular crowding influences enzyme working efficiencies and signalling pathways within cells. The project aims to understand the role of cytoplasm's physical properties in controlling chemical reaction rates.
Ecotech aims to develop scalable solutions inspired by nature to tackle environmental challenges. The field combines biology, engineering, and earth sciences for interdisciplinary collaboration.
Researchers can now build and combine large DNA pieces, redesigning microbes as efficient cell factories for producing complex products like medicines and chemicals. This technology enables sustainable manufacturing, agriculture, and industrial biotechnology, and accelerates microbial cell factory development.
A new CRISPR protein, Cas12a2, has shown potential for killing sick cells while leaving healthy ones untouched. Researchers have tested its effectiveness in destroying cancer cells and virus-infected cells with promising results.
The partnership aims to establish a next-generation C1 biofoundry at DTU to convert CO2, CO, and methane into valuable products. This technology has the potential to reduce industrial emissions and enable circular, climate-positive solutions.
Researchers have developed a new method to build programmable artificial organelles inside living cells using RNA, enabling customization of cellular compartments and tunable properties. This approach may lead to specialized biological functions for nanomedicine and gene engineering.
Volume 39 of SLAS Discovery highlights novel assays and AI-assisted workflows to accelerate personalized cancer immunotherapy. The journal aims to advance life sciences discovery through education, knowledge exchange, and global community building.
Motif Neurotech has received FDA approval to begin the first clinical trial of its therapeutic BCI device, DOT, for treatment-resistant depression. The study will test the device's effectiveness in delivering electrical stimulation to brain circuits linked to depression.
Artificial platelets have been developed that remain stable and effective after a year at room temperature and two months at high temperatures. This technology could enable direct injection of synthetic platelets into bone marrow to treat life-threatening bleeding in remote areas or disaster zones.
Researchers from China have successfully demonstrated CRISPR/Cas genome editing in nonregenerative cotton via sexual hybridization, opening a novel technical avenue for genetic improvement. The approach eliminates toxicity in cottonseed protein, enabling valuable resource utilization and advanced biotechnologies.
A team of researchers at The University of Osaka has created a wireless EEG transmission system that can operate without external power sources. The system harnesses energy from the temperature difference between the human body and surrounding air, allowing it to function reliably even in hot summer conditions.
Researchers have developed a universal toolkit for editing bacterial DNA in 15 diverse species, including human pathogens and fast-growing biotechnology organisms. The technology uses retrons, an immune system that produces DNA, to efficiently modify genes, with varying success rates across different species.
A USC-led team is working on a medical device that uses tears to monitor health, starting with dry eye disease. The device aims to provide continuous monitoring and automated medication delivery, improving patient comfort and treatment efficacy.
Australian scientists have developed an injectable therapy called Snoretox-1 to help clear blocked airways in flat-faced dogs suffering from brachycephalic obstructive airway syndrome (BOAS). The treatment shows early success in improving breathing difficulties in bulldogs.
The book highlights the importance of sustaining innovation in sectors such as semiconductors, biotechnology, and critical minerals to drive economic growth and national security. By rebuilding domestic manufacturing and leveraging new technologies, the US can regain leadership in these areas and capture a $4 trillion market.
Researchers mapped how Sox9 guides cartilage formation in mouse embryonic limbs, finding that it dynamically targets different genes depending on developmental timing and cell type. The study provides a foundation for understanding skeletal development and may contribute to future research on bone and cartilage diseases.
Researchers at VUB and La Monnaie/De Munt have created a world-first shoe using pure mycelium as the sole material, achieving load-bearing capacity without reinforcement. The innovative design showcases the potential of fungal materials in traditional crafts.
Researchers developed a heat-tolerant cutinase enzyme that combines structural rigidity with flexibility, enabling efficient degradation of PET at high temperatures. This discovery provides new insights into designing enzymes for sustainable plastic recycling and addresses the pressing issue of plastic waste.
Researchers create living biohybrid miniature robots that solve traditional engineering trade-offs between structural rigidity and environmental adaptability. These biological engines utilize embodied intelligence to navigate complex terrains and achieve performance metrics rivaling state-of-the-art synthetics.
Duracyte's technology uses an implantable device to produce therapeutic proteins continuously inside the human body, replacing injections and infusions with a single device. The device can sense biological signals, monitor tumor environments and adjust therapeutic output in real time.
A comprehensive review reveals how phospholipid asymmetry governs EV surface charge, providing a unified framework for classification, functional understanding, and standardization in nanomedicine. The study highlights the importance of membrane lipid composition and surface charge in determining EV function.
A new enzyme from a fungus cultivated in sugarcane bagasse or wheat bran can promote cellulose pulp bleaching. The xylanase facilitates the removal of xylan fractions associated with residual lignin, increasing brightness and efficiency in subsequent stages of pulp processing. This non-toxic alternative reduces chemical load and has gr...
A new bioinformatics tool, MPGK, integrates MR, PRS, GO, and KEGG analyses into a single reproducible workflow, reducing technical barriers for researchers. The tool successfully identified causal relationships between diabetes and psoriasis using publicly available datasets.
A review by an international team of researchers highlights that air monitoring is essential for global public health strategies, as airborne antibiotic resistance genes can spread silently between humans, animals, and the environment.
Researchers have repurposed a bacterial DNA synthesis system to enable DNA to act as an active 'field agent' inside living cells. This allows for the creation of programmable DNA fragments that can regulate gene expression and control protein behavior.
A five-year field study shows that small, repeated additions of biochar combined with water-saving irrigation can significantly reduce methane emissions from rice paddies over time while maintaining strong crop yields. Continuous application maintained and strengthened methane reduction, producing net negative emissions in some cases.
The new joint department combines expertise in medical devices, neuroengineering, imaging science, and more to advance biomedical research and translate discoveries into meaningful health advances. The partnership aims to accelerate the translation of discoveries into improvements in human health.
Researchers found that combining biochar with beneficial bacteria significantly improves phosphorus availability, reshaping plant development and increasing crop yields in greenhouse-grown cherry tomatoes. The study also showed that this approach can enhance soil fertility and crop productivity without increasing fertilizer inputs.
Dr. Yangzhi Zhu has been awarded a prestigious Career Development Award from the American Heart Association to support his research in translational biosensing and organ health assessment. The award aims to develop innovative sensing strategies for improving donor organ condition and supporting better clinical care.
A new study presents a framework combining biochar engineering with artificial intelligence to design next-generation materials tailored for specific pollutants. The work highlights how advanced data-driven approaches can accelerate the development of sustainable water treatment technologies.
A new study found that biochar can significantly reduce methane emissions from rice paddies when applied at optimal nitrogen levels. However, high nitrogen inputs may actually increase methane emissions, highlighting the need for careful management of fertilizer inputs.
The Hybrid Oxygenation Bioelectronics system, or HOBIT, shields cells from the immune system while providing access to oxygen and nutrients. The compact device supports higher cell densities in a smaller space, enabling the production of multiple biologic molecules simultaneously.
Four UMass Amherst researchers have been elected as American Association for the Advancement of Science (AAAS) fellows for their distinguished contributions to various fields. Om Parkash Dhankher's work in agricultural biotechnology has led to the development of arsenic-free rice and phytoremediation of toxic metals.
This issue highlights advancements in drug discovery, synthetic biology, and laboratory digitalization. SLAS Technology emphasizes scientific and technical advances that enable improved biomedical research and development.
A new study reveals that nano-biochar fertilizers can actively regulate soil processes and help protect rice from harmful metal accumulation. The findings show improved rice growth, enhanced soil biological activity, and reduced cadmium and arsenic uptake in contaminated soils.
A comprehensive meta-analysis reveals that biochar functions as a highly active biological regulator, restructuring the earth to boost porosity and moisture retention. Biochar disrupts the soil's nitrogen cycle by suppressing specific enzyme activities, slowing down processes like nitrification and denitrification.
A new study reveals that transforming biomass from dedicated energy crops into biochar could provide a cost-effective and scalable solution for removing carbon dioxide from the atmosphere, helping China move closer to its carbon neutrality goals. Biochar can lock carbon in soils for decades or even centuries while improving soil health.
Researchers developed a specially engineered biochar made from sewage sludge that significantly enhances plant growth when combined with beneficial bacteria. The biochar-bacteria combination improved nitrogen cycling and increased the abundance of beneficial soil microbes, leading to greater plant nutrition and growth.
Researchers develop MS-based glycoRNA analytical pipeline for precise structural characterization. Glycan abundance patterns reveal distinctive physiological and pathological states, serving as potential biomarkers.
Dr. Aliesha O’Raw, Principal Investigator at TIBI and Co-Founder of OnVagus, has been selected for the 2026 ACS BrightEdge Entrepreneurs Program. The program provides mentorship, entrepreneur training, and early-stage investment support to advance cancer diagnostic and therapeutic solutions.
BRIGHT at DTU joins forces with Novonesis to develop microbes that can efficiently utilize acetic acid produced from captured carbon, enabling the production of sustainable protein. The collaboration aims to accelerate microbial fermentation and reduce costs, ultimately contributing to a circular bioeconomy.
A novel drug delivery system developed by Osaka Metropolitan University improves Paclitaxel absorption by binding to the lipocalin-type prostaglandin D synthase enzyme, enabling selective delivery to cancer tissues. The system demonstrates significant tumor suppression effects even after administration cessation.
Researchers developed a capsule-based method to analyze individual cells through multiple experimental steps, overcoming a long-standing limitation in cell research. The technology, called semi-permeable capsule technology, allows scientists to keep cells' DNA intact and analyze hundreds of thousands of cells simultaneously.
A conductive bioglue was developed to ensure firm adhesion and stable electrical signaling within the human body. It overcomes challenges in connecting damaged tissues or attaching bioelectronic devices, promoting muscle and nerve regeneration and stable implant stability.
Researchers at IBEC have developed a compact, cost-effective NMR platform capable of direct observation of dynamic metabolic fluxes in microfluidic systems. This technology leverages hyperpolarization to bridge the gap between high-field NMR performance and lab-on-chip analysis.
Researchers develop world's first DNA aptamer that binds to neurofilament light chain, a protein released into the blood with neurodegeneration. The aptamer, MN711, shows high affinity and specificity comparable to commercially available antibodies.
Researchers developed a new noninvasive brain stimulation technique by combining focused ultrasound with electrical stimulation, producing stronger, targeted brain responses. This approach, called transcranial electro-acoustic stimulation, clarifies conflicting results in the field and introduces a new approach to noninvasive brain sti...