Articles tagged with Biosensors
A novel synthetic biology platform enables rapid and cost-effective transformation of protein binders into high-contrast nanosensors for various applications. The platform uses fluorogenic amino acids to increase fluorescence up to 100-fold, enabling the detection of specific proteins, peptides, and small molecules.
A new biosensor prototype can measure biomarkers for heart failure in saliva, promising a more accessible and affordable way to screen for the condition. The device, which resembles a COVID-19 test, could enable people with limited access to medical facilities to check on their health regularly.
Researchers at Tufts University developed a nanomanufacturing approach using water as the primary solvent, reducing environmental impact and opening doors to hybrid electronic-biological devices. The method uses silk fibroin as a surfactant to enhance water's ability to coat surfaces evenly.
Researchers at the University of Cambridge have discovered that gibberellin hormone plays a crucial role in integrating light signaling and stem growth in plants. Using advanced biosensors, they found that gibberellin levels are higher in longer cells and that a specific enzyme called GA20ox1 produces a gradient that controls cell elon...
Researchers at the University of Cambridge have discovered that the plant hormone gibberellin is essential for legume nitrogen-fixing root nodule formation and maturation. The study used a highly sensitive next-generation biosensor to visualize GA accumulation in specific zones of the root, revealing its critical role in nodulation.
A new technological breakthrough has enabled scientists to visualize opioid signaling in the brain in real-time, providing a deeper understanding of how opioids affect the brain. This breakthrough has opened up new avenues for developing more effective and safer therapeutics for pain management and mental health disorders.
The team created microbeads that emit various colors of light depending on the illuminating light and bead size, offering a wide range of applications. The use of plant-derived materials allows for low-cost and energy-efficient synthesis, making them an attractive alternative to conventional luminescent devices.
Researchers have developed a novel metasurface platform with aggregation induced emissions (AIE) biosensors to enhance human serum albumin detection in urine tests. The system improves readings and reduces consumption, making large-scale surveys more accessible.
The Luxembourg Institute of Science and Technology is developing affordable gas sensors for environmental monitoring and occupational safety. The €8 million AMUSENS project aims to create portable, cost-effective sensors using nanotechnology and artificial intelligence.
Researchers discovered that plants employ ABA to close stomata, obstructing spider mites' entry points and significantly reducing pest damage. The closure of stomata also coincides with the production of ABA, a hormone linked with drought response.
Researchers at the University of Washington have solved a long-standing chemical mystery in organic electrochemical transistors (OECTs), which allow current to flow in devices like implantable biosensors. The study reveals that OECTs turn on via a two-step process, causing a lag, and off through a simpler one-step process.
The Lundquist Institute has been awarded a four-year, $2.6 million grant to develop wearable multiplex biosensors that can monitor exacerbation risk in COPD. The proposed sensors have the potential to revolutionize COPD management and transform chronic disease management by providing real-time, non-invasive monitoring.
A handheld device developed by Osaka Metropolitan University's team can detect multiple bacterial species within an hour, including disease-causing E. coli and salmonella. The sensor uses organic metallic nanohybrids to distinguish electrochemical signals on the same screen-printed electrode chip.
Optical microcavities empower biochemical sensing by increasing photon lifetimes and optical field energy density, fostering enhanced sensitivity. Recent advancements have led to breakthroughs in detecting biomacromolecules, cells, and solid particles, with emerging development trends outlined.
A new material has been developed with adaptive durability, meaning it becomes stronger and more conductive when subjected to impact or stretching. The material's conductivity is also improved by adding a small amount of PEDOT:PSS, making it suitable for wearable devices and personalized medical sensors.
Researchers at UT Austin develop tools using AI and biosensors to harness microbes for faster drug production, potentially creating a reliable supply of galantamine. The innovative approach uses genetically modified bacteria to produce a chemical precursor of the medication.
Researchers developed protein-based microcapsules to enhance aptamer sensors, enabling direct detection of target molecules in biological samples. The system demonstrates robust protection against harmful proteins and simultaneous real-time sensing of multiple targets.
Scientists have discovered that the bat brainstem processes echolocation and communication calls differently, with a stronger response to less frequent calls due to better neural synchronization. The findings may also be relevant to medical applications in humans, such as understanding diseases like ADHD or schizophrenia.
Researchers developed a portable, droplet-based millifluidic device to monitor patients in the critical first days after surgery. The device measures drainage fluid's alpha-amylase activity in real time, reducing test duration from six hours to two minutes.
Researchers developed a biosensor to measure hypoxanthine levels in meat, indicating freshness. The sensor achieved over 98% accuracy and was demonstrated on pork tenderloins.
Researchers have developed a hand-held biosensor that can detect breast cancer biomarkers from saliva with high accuracy and efficiency. The device is portable, reusable, and cost-effective, making it an excellent choice for communities or hospitals without access to advanced technologies like MRI.
A research team at Helmholtz-Zentrum Dresden-Rossendorf develops a new approach for fast and cost-effective pathogen detection using miniaturized biosensor devices and systems. The system can simultaneously carry out up to thirty-two analyses of one sample, offering significant advantages over traditional electronic FET-based biosensors.
University of Texas at Dallas researchers have developed a first-of-its-kind, handheld electrochemical sensor that can accurately detect fentanyl in urine within seconds. The device detects even trace amounts of fentanyl with 98% accuracy and could be used to test for the drug in saliva, helping first responders make treatment decisions.
Researchers at UMass Amherst develop graphene-based tattoos to measure cortisol and other biomarkers in sweat. The technology has the potential to provide insights into overall health and serve as a tool for early disease detection, enabling personalized healthcare.
Researchers at Ruhr University Bochum have identified molecules that block CO2 receptors in fruit flies, leading to potential insect repellents. The team's findings could also enable the development of a CO2 biosensor for detecting volatile substances.
The University of Rochester is establishing a new NIH-funded center focused on developing FDA-qualified drug development tools related to barrier functions in disease. Researchers will create microphysiological systems with ultrathin membranes of human cells, aiming to reduce animal trials and improve drug efficacy.
A team of scientists identified VAP as a molecular anchor that stabilizes mitochondria near synapses in dendrites, supporting memory formation and plasticity. The discovery links VAP to ALS-linked protein and suggests that mitochondrial stabilization is critical for neuronal function and health.
A study of 70 autistic youths in psychiatric hospitals found wearable biosensing and machine learning can identify impending aggressive behaviors. The findings suggest a potential for developing adaptive intervention systems to prevent aggression.
Researchers have developed a device that detects glucose and adenosine monophosphate biomarkers in saliva with high sensitivity, enabling easy at-home health monitoring. The electrochemical aptamer-based biosensor is simple, accurate, and stable, making it suitable for use without laboratory equipment.
A study is being conducted to assess the workload in collegiate dancers, examining objective physical activity demands and subjective self-reported perceptions of physical and mental workload. The findings could highlight the importance of healthcare access to reduce injury risk and improve performance in this underserved population.
Researchers at Texas A&M University have developed a miniature, injectable glucose biosensor and wearable device that enables user-friendly, minimally-invasive continuous glucose monitoring. The device addresses challenges associated with existing CGMs, including size and skin tone compatibility.
Researchers developed a handheld, wireless biosensor to detect Alzheimer's and Parkinson's biomarkers from saliva and urine samples. The device has shown high accuracy comparable to existing state-of-the-art methods.
Researchers at Xi'an Jiaotong-Liverpool University have developed a sensitive and robust pH sensor that can detect pH variation in just a few microliters of samples. The new sensor uses novel materials and methods to overcome the current method's limitations, which are not sensitive enough or fragile for commercial-scale use.
Researchers from Ritsumeikan University developed a low-cost, self-powered biosensor for monitoring organic wastewater in freshwater lakes and rivers. The biosensor uses a microbial fuel cell to detect the level of organic contamination in water samples, providing an early warning system for water quality management.
Researchers discovered a wide range of organisms, including microbes and humans, exhibit similar movement patterns to navigate their surroundings. These patterns are thought to be linked to uncertainty management in the brain.
Researchers developed 'acoustic touch' smart glasses that translate visual information into distinct sound icons, enhancing the ability of blind or low-vision individuals to navigate their surroundings. The technology significantly improved object recognition and reaching abilities, empowering independence and quality of life.
Researchers at UC Riverside successfully engineered a plant to turn beet red in the presence of a banned pesticide, enabling an environmental sensor without damaging its native metabolism. This breakthrough opens up possibilities for detecting other toxic substances like drugs and birth control pills in water supply.
Researchers at Gwangju Institute of Science and Technology (GIST) have developed a deep learning-based biosensing platform called DeepGT, which can accurately quantify nanoscale bioparticles, including viruses. The platform harnesses the advantages of Gires-Tournois biosensors and AI to refine visual artifacts and extract relevant info...
A University of Maryland research team is developing a portable bio-nose device capable of identifying complex odors. The team has successfully created an insect-based cell line that can sense odors, and is now studying its responses to different liquids.
A new electroenzymatic assembly transduction strategy-based biosensor has been developed for simultaneous detection of glucose, lactate, and cholesterol in clinical samples. The sensor exhibits high sensitivity and efficiency, with a detection time of under 30 seconds, and good agreement with laboratory results.
Chung-Ang University researchers create an electrochemical DNA biosensor that detects HPV-16 and HPV-18 with high specificity, facilitating early diagnosis of cervical cancer. The sensor uses a graphitic nano-onion/MoS2 nanosheet composite to enhance conductivity.
Researchers at UC Santa Cruz have created a device that mimics biological channels to detect biomolecules indicative of human disease. The bioprotonic system uses electrical currents of protons to translate biomolecule presence into electronic signals, with potential applications for in-vitro and clinical settings.
Researchers have engineered bacteria that can detect tumor DNA in a live organism, using CRISPR technology. The bacteria, Acinetobacter baylyi, were designed to respond to specific DNA sequences associated with cancer, allowing for early detection and potentially preventing disease progression.
Researchers at Johns Hopkins University have developed nanoscale tattoos that can stick to live cells, allowing for the first time to monitor and control individual cell health in real-time. This technology bridges the gap between living cells and conventional sensors, enabling early disease diagnosis and treatment.
Research reveals a local mechanism in neurons that enables insulin-like growth factors to facilitate brain plasticity. IGF release is necessary for activating the IGF1-Receptor during synaptic plasticity, leading to neuron growth and strengthening.
Researchers at Washington University have developed a breath test that can quickly identify those infected with COVID-19, providing accurate results in under a minute. The device uses an electrochemical biosensor to detect the virus, which has potential applications for use in doctors' offices and public events.
Researchers at MPFI discovered Protein Kinase C delta's (PKCd) role in regulating cell-wide gene expression through synaptic plasticity. The study found that PKCd activates biochemical reactions that spread throughout the neuron, influencing gene transcription and memory formation.
Researchers developed modular optical sensors capable of detecting viruses and bacteria using fluorescent carbon nanotubes with DNA anchors. The sensors showed high reliability and selectivity in detecting SARS-CoV-2 protein, offering advantages for complex environments and future diagnostic applications.
A new device, pioneered by Anqi Zhang, can record brain activity without harming neural tissue, using the passageways of blood vessels. This innovation overcomes previous limitations, enabling precise recording from individual neurons in living animals.
A mouse study using novel biosensing technology reveals that enriched environments increase neural connections and boost brain function. The findings could lead to new AI methods inspired by brain plasticity.
Researchers created a real-time air monitor that can detect SARS-CoV-2 variants in about 5 minutes, with potential applications for hospitals, schools, and public places. The device uses an ultrasensitive biosensing technique and aerosol sampling technology to quickly identify airborne virus concentrations.
Researchers at Tokyo University of Science developed a novel wearable biosensor that can monitor sweat electrolyte levels, providing insights into the body's electrolyte balance. The sensor can be seamlessly applied to textiles and transmits measurements wirelessly.
Researchers at Sainsbury Laboratory Cambridge University have found a shoot-to-root signalling pathway triggered by dry air, which tells roots to continue growing and searching for water deeper in the soil. This pathway allows plants to maintain root growth despite reduced photosynthesis and humidity.
The researchers have demonstrated significant improvements for chip-based sensing devices that can detect or analyze substances across widely varying concentrations. They developed signal-processing techniques that enable seamless fluorescence detection of a mixture of nanobeads in concentrations across eight orders of magnitude.
Researchers have developed a three-dimensional mesoporous biosensing-membrane with neighborhood nanostructures, exhibiting excellent sensitivity and long-term stability. The membrane uses a ternary coating to assemble Prussian blue and glucose oxidase, improving cascade reaction efficiency and sensing stability.
Researchers developed a biofuel cell on a chip that measures blood glucose levels using a few microliters of blood. The sensor generates an electrical signal based on the enzyme's reaction with glucose, providing accurate readings using general-purpose devices like smartphones.
A novel method combines biosensors and microfluidics to quickly identify mutant bacterial strains that produce industrially useful proteins. The approach enables the extraction of high-performing strains in a fraction of the time required by traditional methods.
Researchers have developed a novel computational approach to design protein-peptide ligand binding complexes that can trigger complex cellular responses. The new biosensors can sense flexible compounds and provide optimal sensing of molecular signals, potentially leading to improved therapeutic applications.
Researchers developed a living yeast-based dual biosensor that can detect peptide variants with a visible readout, enhancing the capabilities of their original biosensor. The new sensor can distinguish between specific peptide variants using a protease-cleaving catalytic enzyme.
Researchers developed an electronic biosensor using DNA aptamers to detect biomarkers in whole blood samples. The biosensor successfully detected clinically relevant levels of a marker protein for cardiovascular disease without further sample preparation.