Researchers at MPFI discovered Protein Kinase C delta's (PKCd) role in regulating cell-wide gene expression through synaptic plasticity. The study found that PKCd activates biochemical reactions that spread throughout the neuron, influencing gene transcription and memory formation.
Researchers developed modular optical sensors capable of detecting viruses and bacteria using fluorescent carbon nanotubes with DNA anchors. The sensors showed high reliability and selectivity in detecting SARS-CoV-2 protein, offering advantages for complex environments and future diagnostic applications.
A new device, pioneered by Anqi Zhang, can record brain activity without harming neural tissue, using the passageways of blood vessels. This innovation overcomes previous limitations, enabling precise recording from individual neurons in living animals.
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A mouse study using novel biosensing technology reveals that enriched environments increase neural connections and boost brain function. The findings could lead to new AI methods inspired by brain plasticity.
Researchers created a real-time air monitor that can detect SARS-CoV-2 variants in about 5 minutes, with potential applications for hospitals, schools, and public places. The device uses an ultrasensitive biosensing technique and aerosol sampling technology to quickly identify airborne virus concentrations.
Researchers at Tokyo University of Science developed a novel wearable biosensor that can monitor sweat electrolyte levels, providing insights into the body's electrolyte balance. The sensor can be seamlessly applied to textiles and transmits measurements wirelessly.
Researchers at Sainsbury Laboratory Cambridge University have found a shoot-to-root signalling pathway triggered by dry air, which tells roots to continue growing and searching for water deeper in the soil. This pathway allows plants to maintain root growth despite reduced photosynthesis and humidity.
The researchers have demonstrated significant improvements for chip-based sensing devices that can detect or analyze substances across widely varying concentrations. They developed signal-processing techniques that enable seamless fluorescence detection of a mixture of nanobeads in concentrations across eight orders of magnitude.
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Researchers have developed a three-dimensional mesoporous biosensing-membrane with neighborhood nanostructures, exhibiting excellent sensitivity and long-term stability. The membrane uses a ternary coating to assemble Prussian blue and glucose oxidase, improving cascade reaction efficiency and sensing stability.
Researchers developed a biofuel cell on a chip that measures blood glucose levels using a few microliters of blood. The sensor generates an electrical signal based on the enzyme's reaction with glucose, providing accurate readings using general-purpose devices like smartphones.
A novel method combines biosensors and microfluidics to quickly identify mutant bacterial strains that produce industrially useful proteins. The approach enables the extraction of high-performing strains in a fraction of the time required by traditional methods.
Researchers have developed a novel computational approach to design protein-peptide ligand binding complexes that can trigger complex cellular responses. The new biosensors can sense flexible compounds and provide optimal sensing of molecular signals, potentially leading to improved therapeutic applications.
Researchers developed a living yeast-based dual biosensor that can detect peptide variants with a visible readout, enhancing the capabilities of their original biosensor. The new sensor can distinguish between specific peptide variants using a protease-cleaving catalytic enzyme.
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Researchers developed an electronic biosensor using DNA aptamers to detect biomarkers in whole blood samples. The biosensor successfully detected clinically relevant levels of a marker protein for cardiovascular disease without further sample preparation.
Researchers developed a wireless bioresonator using parity–time symmetry to detect minute biological signals, achieving 2000-fold higher sensitivity than conventional systems. The biosensor can measure glucose concentrations ranging from 0.1 to 0.6 mM and lactate levels up to 4.0 mM.
The University of Technology Sydney has developed a brain-computer interface technology that allows users to control devices such as robots and machines using only their thoughts. The technology has been successfully tested in various environments, achieving high accuracy rates of up to 94%. It also has significant potential in fields ...
A new study develops an algorithm to decode the coordinated regulation of cell-edge velocity by Rho GTPases, revealing specific characteristics of each enzyme. The model predicts edge velocity from activity time series with high accuracy.
A new molecular testing device has been developed to identify individuals with high hypnotizability, who are most likely to benefit from hypnosis interventions for pain treatment. The test detected a subset of highly hypnotizable individuals with high levels of postoperative pain.
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Researchers at Pusan National University have developed a novel FRET-based biosensor to detect double-strand breaks in DNA, providing real-time information on γH2AX. The sensor's sensitivity is higher than conventional immunostaining techniques, making it useful for identifying DNA damage factors and elucidating repair mechanisms.
Researchers at Shenzhen University have developed a compact fiber optical nanomechanical probe (FONP) to measure in vivo biomechanical properties of tissue and even single cells. The high-precision mechanical sensing system enables accurate measurements with spring constants as low as 2.1 nanonewtons.
Researchers from Northwestern University have developed a new biosensor device that accurately detects toxic levels of fluoride in water, allowing for easy use outside of a lab. The device has been field-tested in rural Kenya, showing excellent accuracy and usability results.
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A synthetic biosensor created at Cornell University enables the study of proteins in ways previously impossible, leading to potential applications in drug development and environmental sensing. The system uses cell-free synthesis to produce proteins directly into an artificial membrane, allowing for dual optical and electronic readouts.
A new DNA biosensor developed by NIST, Brown University, and the French government-funded research institute CEA-Leti boasts accurate and inexpensive design. The modular device can measure biomarkers in a scalable and high-sensitivity manner.
Researchers developed peptide-based olfactory receptors on graphene surfaces to detect odor molecules. The new system showed highly selective and sensitive detection of various odor molecules, including limonene, menthol, and methyl salicylate.
Researchers at Tohoku University developed a microelectronic fiber that can analyze electrolytes and metabolites in sweat, enabling wearable bioelectronics for monitoring biochemical signatures. The breakthrough smart fabric has the potential to provide greater versatility in functions, larger sensing areas, and greater comfort.
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Researchers at Tufts University develop biopolymer-based sensors that can detect bacteria, toxins, and chemicals in the environment. The sensors glow when dangers are present and can be printed on a wide range of materials, including wearable items and food jars.
A cross-disciplinary team at Northwestern University has developed a sensor platform that can detect environmental contaminants like fluoride in real-world samples. The team used an established riboswitch to build a biosensor for fluoride, encapsulating the sensor inside a fatty membrane to protect it from contaminants.
Researchers developed biosensors to measure real-time energy changes in plant cells, revealing the bioenergetics of pollen tube growth. The study found that mitochondrial respiration is a main source of cytosolic ATP, while plastid glycolysis supplies plastid ATP.
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Researchers from Osaka University developed a new fluorescent sensor system to visualize N-cadherin-mediated interactions between living cells. The INCIDER system enables accurate tracking of temporal changes in these interactions, with a fluorescence signal 70 times stronger than existing methods.
Researchers developed a FRET-based biosensor SMART to visualize necroptosis in living mice, enabling monitoring of this form of regulated cell death in various pathological models. The study successfully characterized necroptosis in vivo using transgenic mice with the FRET biosensor.
A new portable device can detect the low-intensity light emission from healthy plants, allowing researchers to measure their health and sustainability. This technology can help assess the impact of CO2 emissions, greenhouse gases, and extreme weather events on plant stress and inform strategies for sustainable agriculture.
Researchers developed a disposable, fast, and reliable biosensor system to detect putrescine in beef samples, improving food safety. The system uses cell-free protein synthesis and is designed to be consumer-friendly, empowering individuals to check the quality of their food.
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Researchers at KAUST have developed a soft and flexible electronic 'e-skin' that can detect minute temperature differences between inhalation and exhalation, as well as touch and body motion. The material's island-bridge atomic structure provides an inherent softness and flexibility ideal for on-skin applications.
A new microfluidic multiplexed chip uses CRISPR technology to detect SARS-CoV-2 and monitor antibiotic levels, offering a rapid and sensitive solution for managing COVID-19 patients. The test omits nucleic acid amplification and can be easily adapted to new virus mutations.
Researchers at the University of Luxembourg created colour-changing CLCE fibres that can be easily sewn into fabric, shifting colours continuously from red to blue upon stretching, and remain colourful even after repeated wear and washing.
Researchers developed a biosensor that can detect brain cancer from minute blood samples using surface-enhanced Raman spectroscopy. The test distinguishes primary brain tumors from secondary tumors and predicts tumor location within the brain with high accuracy.
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A Brazilian-American research team has identified a subtype of inhibitory interneurons that can gauge speed with great precision. These neurons are more stable than excitatory neurons and may be linked to spatial memory and the ability to remember routes or locations.
Researchers at the University of Münster have identified a specific group of cells in plant roots that react to salt stress, forming a 'sodium-sensing niche' and triggering a calcium signal. This signal is controlled by a calcium-binding protein (CBL8) that helps pump out salt from the plant under severe stress conditions.
Researchers from UMass Amherst have created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue. This breakthrough device has the potential to lead-edge applications in cardiac-disease experiments and improve health monitoring for cardiac disease studies.
A new biological sensor developed by the Hebrew University of Jerusalem has successfully detected hidden rot in potato tubers, one of Israel's chief export industries. The sensor can detect disease before visible symptoms appear, allowing for early identification and prevention of rot and food loss.
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Researchers developed APTASHAPE to analyze protein and metabolite signatures in blood plasma for various diseases. The technology shows promise for non-invasive early detection of bladder cancer and other conditions.
Scientists at Tokyo Medical and Dental University developed an enzyme-based biosensor in the form of an electrospun polymer mesh that can detect volatile organic compounds. The dry-form biosensor, which uses embedded enzymes, has been shown to be highly specific and sensitive to ethanol vapor.
A new light-based sensor harnesses the light-guiding properties of spider silk to detect and measure small changes in the refractive index of a biological solution, including glucose and other types of sugar solutions. The sensor is practical, compact, biocompatible, cost-effective, and highly sensitive.
The new ultrasound sticker uses a stretchy adhesive layer and rigid array of transducers to produce higher resolution images over a longer duration. It has potential applications in clinical diagnosis and could be made into wearable imaging products that patients can take home or buy at a pharmacy.
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Researchers at Gladstone Institutes developed a tool called Retro-Cascorder, which logs a cell's genetic activity for days at a time. This allows scientists to create living biosensors that can record changes to their environment.
Binghamton University researchers have developed a way to turn CDs into flexible biosensors that can monitor electrical activity in human hearts and muscles, as well as lactate, glucose, pH, and oxygen levels. The sensors are fabricated in 20-30 minutes without toxic chemicals or expensive equipment, costing around $1.50 per device.
Researchers have developed a battery-free biosensor that can track glucose levels in sweat using radio frequency signals. The device, resembling a smart necklace, showed promising results in monitoring glucose levels during exercise and has potential applications for detecting other biomarkers in bodily fluids.
Researchers from Indiana University are developing a new biosensor that can analyze samples from 96 individuals in under three hours, with a sensitivity rate of 100% and specificity rate of 90%. The sensor detects not only the virus's spike protein but also the proteins created by the body to protect against the virus.
New research by UMass Amherst professor Jinglei Ping demonstrates the use of graphene for electrokinetic biosample processing and analysis, allowing for faster and more efficient detection of biomolecules. This breakthrough enables the creation of smaller lab-on-a-chip devices with improved time and size efficiencies.
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Researchers at UT Austin create biosensors that can detect therapeutic compounds in bacteria, enabling faster and more accurate analysis. This technology has the potential to revolutionize drug production by providing a sustainable alternative to current processes.
The University of Houston research team has successfully developed a method for 3D printing organic semiconductor devices using multiphoton lithography, enabling the creation of highly conductive microstructures. The technology has potential applications in emerging fields such as nanoelectronics and bioelectronics.
Researchers from NYU Abu Dhabi have developed a simple yet effective approach for on-demand tactile sensing in minimally-invasive surgery. The Smart Laparoscopic Forceps (SLF) system measures grasping force and angle, providing surgeons with relative stiffness index of tissue to help with decision-making during operations.
Researchers have developed innovative tests for multiple chemicals using plant-based molecules that can detect synthetic cannabinoids and banned pesticides. The system uses a simple and inexpensive approach to quickly signal the presence of nearly 20 different chemicals.
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A team led by UMass Amherst food scientist Matthew Moore has received a $750,000 grant to develop portable biosensors for detecting noroviruses and mycotoxins in foods. The technology aims to provide quick, cheap, and effective detection without lab testing.
Researchers developed a biosensor using nanostructured and nanoporous surfaces to detect biomarkers in clinical samples, overcoming technical challenges of small sample amounts. The new technology can provide quick and accurate diagnoses for diseases like prostate cancer without needing dilution or preprocessing steps.
A new nanosensor platform uses machine learning to analyze spectral signatures of carbon nanotubes for early detection of ovarian cancer. The approach detects biomarkers and recognizes the cancer itself, offering a promising alternative to traditional methods.
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A new wearable device can simultaneously monitor glucose, alcohol, and lactate levels, providing users with a comprehensive picture of their health. This technology has the potential to improve disease management for individuals with diabetes and other conditions, as well as enhance overall wellness through real-time tracking.
Researchers developed a disposable electrochemical sensor using graphite-based molecularly imprinted polymers to detect theophylline levels. The sensor can identify low concentrations of theophylline (2.5 μg/mL) in whole blood within 3 seconds, enabling real-time monitoring and potential overdose prevention.
Researchers have developed a rapid COVID-19 test that uses molecularly imprinted polymer nanoparticles to detect SARS-CoV-2. The new test is more sensitive and works under extreme conditions than existing antibody-based tests, with preliminary results indicating it can detect a 6,000-times lower amount of the virus.
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A new e-nose prototype, NOS.E, can distinguish between six whiskies by brand names, regions, and styles in under four minutes, with 100% accuracy for region detection and 96.15% for brand name identification. The technology has applications beyond whisky, including counterfeiting detection in perfume and wine.