Articles tagged with Biosensors
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The five-year grant aims to develop electrobiology techniques that enable applications like living sensors to quickly detect environmental pollutants. The project will involve multiple disciplines, including synthetic biology, protein engineering, soft materials, microsystems integration, and machine learning.
Researchers at Toyohashi University of Technology developed a microchip capable of detecting ultra-low concentrations of prostate cancer antigens using flexible nanosheets. The chip's lower detection limit is comparable to that of large testing devices, enabling fast and accurate diagnosis.
Scientists at Hokkaido University developed a prototype sensor to rapidly measure adenosine triphosphate (ATP) and lactate levels in blood samples. The sensor's sensitivity allows for the accurate detection of these molecules, enabling rapid assessment of disease severity.
The study reveals new details about the conditions under which WDR5 starts and stops interacting with other proteins, allowing researchers to better understand its multitasking role in cancer. The biosensor's ability to recognize different types of protein connections will help develop more effective drugs to target WDR5.
Scientists have developed a genetically encoded biosensor called OxLight1, which enables them to study the action and release mechanisms of neuropeptides like orexin in living mice. The researchers found that the level of orexin release correlates with neuronal activity, revealing previously invisible aspects of healthy brain function.
Researchers developed a waterproof biosensor that can accurately detect changes in potassium and sodium ion levels important in TBI. The chip features electronic components that produce an electrical signal when sensing chemicals, and the team successfully tested it in artificial cerebrospinal fluid and human blood serum.
Researchers at the University of Bath have developed a novel chemical glucose sensing method based on boronic acids and graphene foam. The new technique can accurately detect lower glucose concentrations than current systems, making it ideal for chronic conditions like diabetes.
A new wearable sensor has been developed using MXene nanomaterials that can detect changes in pH levels in sweat, which correlate with muscle fatigue. The device measures electrical resistance patterns in response to mechanical stress and pH changes.
EG-CNTFET biosensors have demonstrated high sensitivities toward several analytes, but challenges remain to overcome, such as selective detection in complex media.
A novel carbon-based biosensor developed at the University of Technology Sydney detects electrical signals sent by the brain, translating them into commands for autonomous robotic systems. The biosensor overcomes three major challenges in graphene-based biosensing: corrosion, durability, and skin-contact resistance.
A recent University of Waterloo study shows that wearable biosensors can provide insight into patterns of health-related behaviour and disease symptoms, enabling remote monitoring of people with complex health conditions. The study found that participants were willing to wear multi-sensor devices for extended periods, highlighting the ...
Researchers at Georgia Institute of Technology created soft flexible photodetectors that are up to 200% stretchable and can detect fainter light levels than conventional devices. The breakthrough material has potential applications in medical wearable sensors, implantable devices, and intelligence systems.
Scientists at Oak Ridge National Laboratory developed a self-detect solution to monitor CRISPR gene editing tools in organisms. The system uses a biosensor guide RNA and reporter protein to trigger the technology's reveal itself, enabling real-time detection of CRISPR activity.
The study uses a new barcode system to track complex signaling activities in cancer cells and identify key protein interactions. The technique enables real-time analysis and synchronization of protein activity over time.
Researchers have genetically engineered bacteria to detect specific chemicals in the gut, which can help maintain balanced neurotransmitter levels. The bacteria, called Escherichia coli Nissle 1917, produce enzymes that degrade or synthesize target chemicals, potentially alleviating mental health issues.
Lactate sensors in wearables aim to monitor athletes' exertion levels, but the connection between sweat and blood lactate remains unclear. Researchers propose improvements to electrochemical sensors and develop an epidermal patch containing a lactate biosensor.
Researchers at Rutgers University have linked Fragile X and SHANK3 deletion syndrome, both associated with autism and health problems, to walking patterns. The study used motion-sensored sneakers to detect gait problems 15-20 years before clinical diagnosis, offering a potential framework for early intervention.
Researchers develop VICE biosensor to assess toxicity of substances on human cells, providing a non-invasive method for early detection. The technology aims to address limitations of current toxicological assessments, which often fail to detect long-term side effects.
Researchers developed a wearable, biocompatible, and low-cost biosensor that measures electromyography signals in muscles. The sensor uses a gold-silver nanocomposite printed onto fabric, providing a comfortable and effective way to track muscle activity.
A team of scientists developed a simple-to-implement plasmonic optical fiber biosensing platform to detect estrogenic endocrine disruptors. The platform can detect EEs down to 1.5 ng L^-1 estradiol equivalent concentration, the lowest limit of detection for any estrogen receptors-based detection reported to date.
A team of engineers and biotechnologists has developed a biosensor that measures antibiotic levels in breath, mirroring blood concentrations. This breakthrough enables on-site, personalized dosing to minimize resistant bacteria strains.
Mycotoxins are toxic secondary metabolites of fungi that contaminate agricultural products, posing severe health risks. Aptasensors utilize aptamers to specifically detect mycotoxins with high sensitivity and specificity, allowing for fast and reliable detection in field settings.
Researchers developed lab-on-a-chip optical biosensors for real-time COVID-19 detection, overcoming low viral load challenges. These sensors utilize light beam interactions to detect viruses, enabling faster diagnosis and controlling outbreaks.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
NTU scientists create soft and stretchable battery powered by human perspiration, suitable for wearable devices. The battery generates electricity in the presence of sweat, providing a sustainable alternative to conventional batteries.
A new genosensor, developed by a Brazilian research team, can detect the genetic sequence of SARS-CoV-2 in saliva or other body fluids with high sensitivity. The device can analyze samples in 30 minutes for a cost of less than $1 per genosensor.
Researchers review advancements in biosensing technologies for neonatal sepsis diagnosis, highlighting the need for faster and more accurate methods. Biosensors offer a promising solution, detecting multiple parameters simultaneously with high sensitivity and accuracy.
Researchers developed amperometric biosensors to determine diclofenac levels in food, improving detection limits and accuracy. The study found that diclofenac inhibits tyrosinase enzyme activity, enabling its detection in milk and other dairy products.
Researchers have developed wearable biosensors that can be integrated into standard face masks to detect SARS-CoV-2 and other pathogens. The technology, called wFDCF, involves synthetic biology reactions embedded in fabrics, providing rapid detection with accuracy comparable to PCR tests.
A new biosensor developed by Purdue University can record and image tissues and organs simultaneously during surgery, allowing for accurate localization of critical regions. The sensor's unique design and soft bio-inks enable seamless interfacing with the curvilinear surface of organs, making it suitable for various sizes and shapes.
A research team from Los Alamos National Laboratory and Purdue University developed bio-inks for biosensors that can localize critical regions in tissues and organs during surgery. The new biosensors allow for simultaneous recording and imaging, which could be useful during heart surgery to guide surgical interventions.
A Spanish research team has developed a low-cost, easy-to-use biosensor to detect breast cancer in its earliest stages. The biosensor provides results in under an hour and can help address limitations of current diagnostic methods.
Researchers demonstrate simultaneous imaging of up to 6 subcellular targets with low crosstalks and high temporal resolutions. They achieve full-frame high sensitivities in quantifying mitochondrial matrix pH and intracellular macromolecular crowding.
Researchers at NIST and VCU have developed a new approach to building better 'nanopore' biosensors by measuring the energy required for molecules to interact with these sensors. This laser-based heating method enables faster and more accurate measurements, potentially revolutionizing disease detection and treatment.
Researchers develop new technique to hyperpolarize and purify fumarate for MRI, offering cost-effective and convenient way to track metabolism in real-time. The method has potential applications in monitoring tumor responses to therapy and imaging acute kidney injuries.
Scientists at Tokyo University of Science develop biofuel cells that use lactate to generate power for wearable devices. The new design can drive a commercially available activity meter for 1.5 hours using one drop of artificial sweat.
Scientists have developed a novel sensor that makes auxin visible in living plants, providing new insights into plant development and growth. The sensor allows for real-time detection of changing environmental conditions and the influences of external stimuli.
Bias in medical devices results in undesirable performance variation across demographic groups, influencing health inequality. Medical engineers can learn from computer science's approach to address bias in devices.
A study from Brazil's University of São Paulo used self-assembled molecular monolayers to create biosensors for detecting the gene PCA3, which is specific to prostate cancer cells. The technique can also be used to diagnose infectious diseases like COVID-19, offering a non-invasive alternative to current methods.
GIST scientists create a radiative cooler that keeps wearable devices cool even under direct sunlight, enabling accurate measurements and improving human body monitoring. The innovative material has high reflectivity and emissivity, making it suitable for outdoor wearables.
Researchers developed a sensor to quantify hydrogen peroxide concentrations near cell membranes, providing insights into cellular processes and potential therapeutic strategies. The biosensor uses surface-enhanced Raman spectroscopy to detect changes in molecular signatures.
A new silicone-based patch fabrication technique fabricates thin patches that rapidly wick water away from the skin, reducing skin irritation caused by wearable biosensors. The technique was developed to improve comfort and performance of wearable bioelectronics.
Researchers reveal how plant roots generate a distinct gradient of gibberellin, a key growth regulator. A mathematical model combined with experimental observations showed that elongation-zone cells produce high levels of GA synthesis and increased permeability contribute to the gradient.
Researchers at Linköping University developed implantable biosensors that monitor sugar levels in plants in real-time. This technology has the potential to optimize crop growth and quality, as well as guide the production of new plant varieties that can thrive in challenging conditions.
Researchers developed more sensitive and efficient biosensors to detect specific sequences corresponding to P. jirovecii using nanotechnology and capture probes. These sensors can detect the fungus in real time without prior amplification steps, enabling a reliable diagnosis of infectious diseases.
Despite advances in biosensor antifouling approaches, further development is needed to increase our arsenal of robust antifouling protection methods. Researchers have developed various techniques such as physical barriers, chemical treatments and selective membranelike coatings to protect biosensors from fouling.
Researchers review graphene quantum dots (GQDs) synthesis methods and their application in biosensors. GQDs are valued for excellent photoelectric properties, good biocompatibility, and low cytotoxicity, making them suitable for novel luminescent nanomaterials.
The SciFiMed project develops a multiplex detection system to examine the functional activity of seven complement factor H related proteins in patient samples. This technique helps diagnose inflammatory diseases such as macular degeneration with higher accuracy.
Scientists discovered molecular basis for how shapeshifting immune system protein XCL1 evolved, outlining principles for designing metamorphic proteins as transformers. These principles can be used to develop biosensors, build nanoscale machines, and even create therapeutics.
Researchers are developing a low-cost, easy-to-use platform to diagnose viral infections in point-of-care settings. The novel technology has high sensitivity and specificity, detecting viral proteins with high accuracy.
A semiconductor chip has been developed to detect antigen concentrations as low as 1 part per quadrillion molar mass, enabling ultra-sensitive detection on a portable scale. This technology uses organic nanosheets and can detect biomolecules in real-time, paving the way for quick disease diagnosis and telemedicine applications.
UC Santa Barbara researchers develop a method to increase both affinity and cooperativity in aptamer-based biosensors, allowing for fine-tuned regulation of receptor properties. This approach enables precision biosensing applications, such as detecting low concentrations of target molecules like chemotherapy drugs.
Scientists at UVA Health System created a simpler, more effective method to convert green fluorescent biosensors to red, improving their ability to monitor multiple targets and peer into tissues. This innovation has the potential to accelerate research in fields such as insulin secretion control and neural activity patterns.
A team of scientists has developed LAMDA, a compact lab-on-paper strip that can diagnose mosquito-borne diseases in under an hour. The device uses Loop-mediated isothermal amplification to detect viral RNA and has great potential for resource-limited clinics and point-of-care diagnostics.
The new diagnostic technique allows direct detection of disease-specific miRNA, breaking through current limitations in early disease detection. The technology is expected to be available to medical practitioners in the next five years, offering a cost-effective solution for rapid and early diagnostics.
LONs have shown outstanding properties in designing membrane-anchored biosensors and synthetic membrane channels due to their information-transfer and self-assembly abilities. They also have great potential in making contributions to developing new therapies and controllable nanoreactors.
Researchers at the University of Münster used a new method to monitor plant metabolic processes in real-time, revealing key mechanisms in energy metabolism and their connection to environmental factors. The study provides new insights into plant responses to stressors like light, temperature, and pest infestation.
A new study applies liquid-metal synthesis to create atomically-thin tin-monosulfide with excellent electronic and piezoelectric properties, enabling flexible nanogenerators for wearable electronics and biosensors. The resulting material displays high durability and flexibility, making it suitable for commercial implementation.
Boston University researchers have developed artificial genes called biosensors that can detect changes in signaling molecules, which are molecular on/off switches inside cells. These biosensors have the potential to improve drug development by allowing researchers to study G-proteins more accurately and easily.
Scientists have created a highly sensitive glyphosate detection method using elastic hydrogel microparticles that inhibit binding to a chip surface. The method offers an extremely high level of sensitivity with regard to pesticide limits for drinking water.