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Bioengineered nanoparticles show promise for fibrinogen manufacture, says Journal of Pharmaceutical Analysis study

Researchers developed a novel polymeric nanoparticle that selectively binds to fibrinogen in human plasma, offering a simpler and less expensive way to manufacture fibrinogen concentrate. This breakthrough could lead to the creation of more efficient fibrinogen-specific affinity reagents for drug development.

SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateJan 13, 2022

Development of rapid and simultaneous diagnosis of COVID-19/influenza diseases by manipulating microfluidic flow with a microfluidic chip

Researchers developed a microfluidic chip for rapid and simultaneous diagnosis of COVID-19 and influenza diseases, achieving results within 30 minutes. The device uses the LAMP method for genetic amplification and has potential applications in various fields beyond human infectious diseases.

SourceToyohashi University of Technology (TUT)·JournalLab on a Chip·TypeExperimental study·DateJan 4, 2022

Quantum brain sensors could be crucial in spotting dementia after University of Sussex scientists find they can track brain waves

Researchers have developed highly sensitive quantum sensors for the brain that can detect magnetic fields generated when neurons fire. This technology introduces a new method to spot bio-markers of early health problems, such as Alzheimer's disease. The sensors are believed to be more accurate than existing EEG and fMRI scanners.

SourceUniversity of Sussex·JournalScientific Reports·TypeExperimental study·DateNov 18, 2021

New imaging technology developed by UCLA research team may reduce need for skin biopsies

A new virtual histology technology may reduce the need for invasive skin biopsies, providing a biopsy-free solution for rapid diagnosis of malignant skin tumors. The technology uses deep-learning frameworks to transform images of intact skin into detailed, virtually stained images.

SourceUniversity of California - Los Angeles Health Sciences·JournalLight Science & Applications·TypeExperimental study·DateNov 18, 2021

NTU Singapore scientists create device that uses ‘light tweezers’ to trap and move viruses

Researchers developed a device that uses light to manipulate and isolate individual viruses, enabling precise diagnosis, treatment, and study of viruses. The device has the potential to aid in vaccine development and research on SARS-CoV-2 virus, allowing for targeted analysis of specific virus mutants.

SourceNanyang Technological University·JournalACS Sensors·TypeExperimental study·DateOct 26, 2021

Building a better dipstick

Researchers at Georgia Institute of Technology have developed a flow control technology to overcome limitations of traditional dipstick tests. This technology enables complex biomedical assays and can detect multiple pathogens, including SARS-CoV-2 and influenza viruses.

SourceGeorgia Institute of Technology·JournalACS Sensors·DateOct 18, 2021

Monitoring glucose levels, no needles required

A team of Penn State researchers has created a noninvasive, low-cost sensor that can detect glucose in sweat, enabling less intrusive glucose monitoring for people with diabetes. The device uses a nickel-gold alloy and is flexible enough to be worn on the body.

SourcePenn State·JournalBiosensors and Bioelectronics·DateOct 14, 2021

Researchers demonstrate a more effective personal protective equipment strategy for COVID-19

Researchers developed a reusable respirator hood that is significantly preferred by frontline healthcare workers and support staff due to its safety and comfort. The new PPE strategy has also led to cost savings and reduced environmental impact, with over 80% of staff requesting their respirators for future use.

SourceUniversity of Southampton·JournalFrontiers in Medical Technology·TypeObservational study·DateOct 14, 2021

A cryptography game-changer for biomedical research at scale

Researchers have developed a federated analytics system, FAMHE, that enables healthcare providers to collaborate on statistical analyses and machine learning models without exchanging underlying datasets. The system has been proven mathematically secure and accurately reproduced published studies in multi-centric settings.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNature Communications·TypeData/statistical analysis·DateOct 11, 2021

Engineers 3D-print personalized, wireless wearables that never need a charge

Researchers at the University of Arizona have created custom-fitted wearable devices that can monitor physiological parameters without needing recharging. The biosymbiotic devices use wireless power transfer and compact energy storage to enable continuous operation, providing accurate data on body temperature, strain, and muscle deform...

SourceUniversity of Arizona College of Engineering·JournalScience Advances·DateOct 8, 2021

JILA’s comb breathalyzer is now a thousandfold more sensitive to disease biomarkers

Researchers at JILA have enhanced the sensitivity of their decade-old frequency comb breathalyzer to detect four biomarkers of disease in human breath. The upgraded system can also identify six additional chemicals, with potential implications for COVID-19 testing and real-time health monitoring.

SourceNational Institute of Standards and Technology (NIST)·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 4, 2021

Graphene made with lasers for wearable health devices

A Penn State-led international research team developed laser-induced graphene (LIG) for wearable health devices, offering superior conductivity and heat resistance. The LIG foam exhibited electrical properties, while fibrous structures showed better performance, opening possibilities for sensing devices.

SourcePenn State·JournalScience China Technological Sciences·DateSep 9, 2021

Smart dental implants

Researchers have developed a smart dental implant that resists bacterial growth and generates its own electricity through chewing and brushing. The implant uses a nanoparticle-infused material that repels bacteria and an embedded light source powered by piezoelectric properties to conduct phototherapy.

SourceUniversity of Pennsylvania·TypeExperimental study·DateSep 9, 2021

Epilepsy brain implant does not transform patients’ sense of self or personality but offers them new insights into illness, study shows

A new study found that a next-generation brain implant for treating refractory epilepsy does not induce changes to patients' personalities or self-perceptions. The study follows 12 patients and their family caregivers over two years, providing reassurance for patients implanted with this device.

SourceTaylor & Francis Group·JournalAJOB Neuroscience·TypeCase study·DateSep 2, 2021

Improving strength, stretchiness and adhesion in hydrogels for wound healing

Researchers from Terasaki Institute for Biomedical Innovation develop methods to enhance mechanical properties of hydrogels, including toughness, stretchiness, and adhesive strength. By introducing dopamine and alkaline conditions, they create gel-like materials with improved biocompatibility and regenerative capabilities.

SourceTerasaki Institute for Biomedical Innovation·JournalACS Applied Materials & Interfaces·TypeExperimental study·DateAug 30, 2021

Remote learning shown to be effective for preparing clinicians as wheelchair-skills trainers

A new study by Spinal Cord Injury Model System investigators found that remote wheelchair-skills training increases clinician confidence in teaching peers. The training program improved trainees' ability to navigate real-world spaces, empowering them to engage with their communities. This innovative approach has the potential to expand...

SourceKessler Foundation·JournalArchives of Physical Medicine and Rehabilitation·TypeObservational study·DateAug 30, 2021

Artificial intelligence re-stained images of tissue biopsy expedite diagnoses

Researchers at UCLA have developed a computational technique powered by artificial intelligence that transforms images of tissue previously stained with H&E into new ones with added special stains. The process takes less than one minute per tissue sample, significantly improving diagnoses in medical conditions such as organ transpl...

SourceUniversity of California - Los Angeles·JournalNature Communications·TypeExperimental study·DateAug 26, 2021

‘Safe and well tolerated’ - the prototype breathing device for covid patients

A low-cost prototype breathing device designed for poorer-resourced healthcare settings has shown promising results in a pilot trial involving healthy volunteers. The device provides continuous positive airway pressure (CPAP) therapy and operates with oxygen concentrators, which are commonly used in low-pressure systems.

SourceUniversity of Leeds·JournalFrontiers in Medical Technology·TypeExperimental study·DateAug 24, 2021

SUTD researchers develop liquid metal antenna that can conform to soft biological tissues

SUTD researchers developed a liquid metal antenna that can conform to soft biological tissues, addressing the mechanical mismatch at the tissue-device interface. The antenna demonstrated high wireless powering efficiency and stability under extreme deformations, making it suitable for implantable devices in hard-to-reach lesions.

SourceSingapore University of Technology and Design·JournalAdvanced Materials·DateAug 20, 2021