‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers at North Carolina State University have developed a controlled evolution technique that dramatically increases plasmid DNA (pDNA) production in E. coli bacteria. This breakthrough could significantly reduce the cost of gene therapies and expedite research, making pDNA resources more accessible.
SourceNorth Carolina State University·JournalMicrobial Cell Factories·TypeExperimental study·DateAug 13, 2025