Articles tagged with Gene Therapy
A new form of gene therapy has been tested to prevent blockages that occur after bypass surgery, with four patients showing successful results. The treatment aims to reduce cell growth and atherosclerosis in grafted vessels, which can fail due to up to 50% of cardiac and leg bypass surgeries.
A study by scientists at NIAID found that gene therapy can result in prolonged production of functionally normal white blood cells in patients with chronic granulomatous disease. This finding has important clinical implications for the treatment of this rare immunologic disorder.
Researchers have developed a gene therapy technique that restricts the activity of genes used for gene therapy to specific cell types, bypassing safety hurdles. This discovery could lead to targeted treatment of cardiovascular diseases and other disorders.
Scientists at Case Western Reserve University have created artificial human chromosomes, offering a powerful tool for studying human genetics and potentially treating genetic diseases. The synthetic microchromosomes demonstrate normal centromeric activity, genetic stability, and continued gene expression.
Brown University researchers have developed a novel oral drug delivery system using erodible plastic microspheres that can improve the efficacy of drugs like insulin. The microspheres, engineered with bioadhesive polymers, increase absorption rates and enhance therapeutic effects.
Researchers at University of Pittsburgh Medical Center have made significant progress in treating rheumatoid arthritis using gene therapy. They successfully expressed the interleukin-1 receptor antagonist (IL-1Ra) gene in synovial cells within joints treated with the approach.
Researchers have developed a gene therapy technique that can produce and secrete proteins into the bloodstream indefinitely, without the need for viral delivery systems. This could drastically decrease the cost of treatments for certain types of anemia, which affect over 140,000 people in the US annually.