Research on the tests that detect and monitor disease. Covers blood tests, cancer monitoring, emergency diagnostics, and new patent-pending assays.
A quality improvement audit found that a volume-based system increased EN volume intake, calories, and protein delivery in mechanically ventilated ICU patients, improving nutrition outcomes.
The Stanford-developed eye implant is a tiny device that measures intraocular fluid flow and provides data on eye pressure. This information can help doctors tailor treatment plans, potentially improving outcomes for glaucoma patients. The device is currently designed to fit inside a standard intraocular lens prosthetic.
A study analyzing over 3 million infants screened for SCID found an incidence rate of 1 in 58,000 births. The survival rate for SCID-affected infants is high at 87%, with further improvements seen when transplantation, enzyme replacement, and gene therapy are used.
A UCSF study found significant price differences in common blood tests across California hospitals, with prices ranging from $35 to $7,303. Hospital ownership and teaching status explain some variation, but factors like location and labor costs do not.
Researchers at Tel Aviv University developed a diagnostic tool using involuntary eye movements to accurately diagnose Attention Deficit Hyperactivity Disorder (ADHD). The test showed a direct correlation between ADHD and the inability to suppress eye movement in anticipation of visual stimuli.
A recent study found that flexible sigmoidoscopy screening significantly reduced the incidence of colorectal cancer by 20% and mortality rate by 27%, compared to no screening. The screening method was effective in reducing the risk of colorectal cancer, regardless of age group.
Researchers developed a highly accurate test to detect surprise ingredients that are neither sweet nor flavorful in ground, roasted coffee. The test uses liquid chromatography and statistical tools to identify unwanted additives, such as grains or plant parts, with 95% accuracy.
Research suggests that physically fit sixth-grade girls are less likely to report feeling depressed when they reach seventh grade. Fitness programs can help prevent depression in middle-schoolers, but schools should also use other interventions like therapy.
Researchers found that consuming two servings of pistachios per day lowered vascular constriction during stress and improved neural control of the heart in adults with well-controlled Type 2 diabetes. The pistachio diet also showed improvements in sleep blood pressure, vascular response to stress, and vagal control of the heart.
A study found that declines in visual perception speed are strongly related to declines in intelligence in old age. The researchers tested 600 healthy older people on a simple task of visual perception and found that the brain's ability to make correct decisions based on brief visual impressions limits complex mental functions.
Scientists at the Salk Institute have discovered a compound in the Voacanga africana plant that protects cells from altered molecular pathways linked to neurodegenerative diseases. The compound, voacamine, has shown anti-inflammatory and neuroprotective effects, suggesting potential as a treatment for Alzheimer's, Parkinson's, and stroke.
A new study published by University at Buffalo medical faculty finds that many of the same symptoms are common to concussions and to injuries to the neck and/or balance system, known collectively as cervical/vestibular injuries. Determining which condition a patient has experienced is critical, as courses of treatment are very different.
A survey of hospital beds in Ireland revealed a high frequency of potential entrapment gaps, particularly in zones 2 and 3. The study emphasizes the importance of monitoring and maintaining bedrails to prevent head and neck entrapments.
Scientists have developed a rapid, at-home test to detect low levels of caffeine in most beverages and breast milk. The enzyme-based test can pick up on caffeine concentrations as low as 1-5 parts per million, helping to prevent serious health problems.
Researchers at Weizmann Institute of Science discover that genetic mutations affecting only half the population, like those causing male sterility, occur twice as often as those affecting males and females equally. This finding has implications for understanding causes of genetic diseases and developing targeted treatments.
A new test diagnoses motoric cognitive risk syndrome (MCR), which combines gait speed measurement with cognitive questions. People who test positive for MCR are twice as likely to develop dementia within 12 years, emphasizing the importance of early diagnosis and potential underlying cause identification.
A recent study published by researchers from UC Davis Alzheimer's Disease Center and the University of Victoria found that early life experiences, such as childhood socioeconomic status and literacy, have a greater influence on the risk of cognitive impairment late in life than demographic characteristics like race and ethnicity. The s...
A new investigation by The BMJ raises concerns about the top-selling blood-thinning drug dabigatran, citing withheld company information and potential flaws in regulatory decisions. Key findings suggest that monitoring blood levels could reduce major bleeding risks by up to 30-40%.
Researchers have identified a connection between misfolded proteins associated with Alzheimer's disease and preeclampsia, potentially leading to improved diagnostic methods. A new urine test using Congo Red dye has already shown promise in identifying the presence and severity of preeclampsia.
Researchers developed a new protein biomarker test platform that can accurately measure multiple proteins indicative of diseases like graft-versus-host disease. The test uses aqueous two-phase systems and no washing steps, enabling simultaneous measurement of multiple diagnostic proteins.
Researchers propose reusing bubble wrap as a sheet of small, test tube-like containers for storing biological samples or chemicals. This could provide numerous benefits in resource-limited regions due to its availability, flexibility, and ease of disposal.
A new study from Rice University found that older adults are nearly twice as likely as their younger counterparts to have memories affected by environmental distractions, leading to decreased memory accuracy and speed. This research provides valuable insights into how the brain is affected by environmental interference, critical inform...
A new Tel Aviv University study confirms that Parkinson's sufferers exhibit greater creative energy than healthy individuals. Researchers found that Parkinson's patients offered more original answers and thoughtful interpretations during testing.
A portable, microchip-based test can diagnose type-1 diabetes outside hospital settings, distinguishing it from type-2 diabetes. The test uses nanotechnology to detect auto-antibodies in the blood, providing a more efficient and cost-effective solution for patients and researchers.
A study by Nationwide Children's Hospital researchers found that an immune marker can predict which critically ill children with traumatic injuries are at risk of developing a hospital-acquired infection. The study suggests that immune system function plays a critical role in preventing infections in these patients.
A study by Brown University researchers found that Rhode Island's Lead Hazard Mitigation Law has significantly reduced blood lead levels in children living in compliant buildings. However, only 20% of properties covered by the law were in compliance, with average lead levels still above 5 micrograms per deciliter in noncompliant homes.
A new TB test uses a fluorescent substrate to detect the BlaC enzyme in sputum samples, enabling fast and accurate diagnosis. The device is portable, easy to use, and undercuts current methods, with a target price tag of less than $1000.
A new national model for bovine tuberculosis (bTB) in Great Britain highlights the need for improved testing, vaccination of cattle, and culling infected farms as effective strategies. The majority of herd outbreaks are caused by multiple transmission routes, including failed tests, cattle movement, and environmental reservoirs.
Researchers at Johns Hopkins Bayview Medical Center introduced guidelines and changes to the computerized provider order entry system to reduce redundant biomarker testing. This led to a 66% decrease in tests ordered and saved an estimated $1.25 million in laboratory charges.
Research highlights significant barriers to driving evaluations for older adults, including high insurance costs and low awareness among healthcare providers. The study suggests improved referral systems and third-party reimbursement could increase participation.
A study found that lab monitoring tests are not always ordered as recommended, with factors such as specialist status, age, and general health influencing the use of these tests. The research suggests that interventions to improve laboratory monitoring should focus on areas with the greatest potential for improvement.
Researchers have developed a device that uses smartphones to measure cortisol levels in saliva, providing an inexpensive alternative to current lab-based tests. The new technology is expected to cost less than $5 and take less than 10 minutes to administer.
Researchers at Intermountain Medical Center developed a simple saliva test that uses a smartphone to quantify and interpret cortisol levels in five minutes. This new technology helps identify adrenal insufficiency, monitor cortisol replacement, and assess physiologic changes in adrenal function.
A new study suggests that growth hormone treatment in children with idiopathic short stature may exacerbate feelings of depression and emotional distress. The research found that children treated with GH showed worsening symptoms of depression and withdrawal compared to those not receiving the treatment.
A study suggests that eHealth interventions, such as interactive websites and video games, can reduce high-risk sexual behaviors and increase HIV testing among men who have sex with men. Digital outreach efforts on social networks and chat rooms also showed promising results in increasing HIV testing and reducing shame felt by young men.
A pilot study will evaluate advanced artificial pancreas technology for individuals with type 1 diabetes under real-world conditions. The study aims to test the safety and effectiveness of an unsupervised artificial pancreas system that automatically controls insulin delivery.
A recent study has found that hypothyroidism can cause impaired driving abilities, comparable to the effects of drinking alcohol. The research suggests that patients with significant hypothyroidism should avoid driving until they have been treated with thyroid hormone.
A new study from Turkey finds that women with gestational diabetes perform worse on cognitive function tests, including a 30-point test for mild cognitive impairment and visual memory tests. The researchers suggest that early interventions and therapies may delay cognitive impairment in diabetes.
A blood kisspeptin level test may effectively predict the risk of miscarriage in pregnant women, with levels 60% lower than those in healthy pregnancies associated with a higher risk. The test more accurately predicted future miscarriage compared to hCG levels.
A recent study by Dartmouth-Hitchcock Norris Cotton Cancer Center found that 22 out of 552 women had their tumor type incorrectly classified using conventional HER2 testing. The study confirmed the importance of accurate HER2 testing, as incorrect classification can have significant implications for treatment decisions.
A new study by Northwestern University found that community-based outreach programs can significantly increase colorectal cancer screening rates among low-income and minority populations. By using a combination of automated reminders, mailed letters, phone calls, and personal outreach, the program was able to nearly double screening ra...
Researchers propose mailing fecal immunochemical tests to improve colon cancer screening rates among low-income communities, where disparities are most prevalent. Follow-up diagnostic colonoscopies often face cost barriers, which exacerbate existing health inequities.
A multipart intervention increased adherence to annual fecal occult blood testing for colorectal cancer screening, particularly among vulnerable populations. The study found that 82.2% of patients who received the intervention completed screening compared to 37.3% of those in usual care.
Women with weight problems exhibited impulsive behavior when presented with images of food, suggesting a possible predisposition to binge eating. The study found that these individuals lacked contemplative will power and were more stimulated by food images.
A new device can collect and detect Listeria monocytogenes on food industry surfaces in just three to four hours, a significant improvement over current methods that take days. The sensor uses compressed air and water to remove cells before detecting them with an antibody, producing a fluorescent signal.
A new TVR pilot may exacerbate the spread of bovine TB by altering badger behavior, according to researchers. The test aims to vaccinate healthy animals and cull infected ones, but its limitations mean many badgers carrying TB could be missed.
A study by St. Michael's Hospital found that nearly 75% of Ontarians with diabetes did not receive all recommended tests due to doctor payment models. Capitation models led to better care for patients, while traditional fee-for-service models resulted in lower quality care.
A study published in mBio suggests that the virulent US fish epidemic emerged from an Asian source, with the bacterium Aeromonas hydrophila causing serious infections in catfish. Researchers identified a common ancestor responsible for the virulent strains of A. hydrophila affecting both China and the United States.
New research reveals that up to 10.1% of people who have a heart attack are newly diagnosed with diabetes due to unrecognized A1C levels. Recognizing diabetes in these patients is crucial as it can guide treatments for coronary artery disease and prevent additional cardiovascular complications.
The University of Surrey has been awarded a Grand Challenges Explorations grant to develop an affordable test for human tuberculosis. The project aims to modify the BCG vaccination and design a new skin test that only gives a positive result when someone has the infection, making it more sustainable in developing countries.
Researchers have developed a prototype device that can analyze various electrolyte levels on the spot, providing real-time feedback to users. The wearable microneedle device is painless and samples only interstitial fluid, making it suitable for long-term use.
Colorectal cancer screening should continue beyond age 75 for previously unscreened patients, according to new guidelines. Practices that implement a patient-centered medical home model with electronic health records (EHRs) have shown improved quality of care compared to non-PCMH practices.
People with high levels of cynicism are three times more likely to develop dementia than those with low levels, according to the study. High cynicism was also initially linked to earlier death, but this association disappeared after adjusting for other factors.
Exposure to environmental toxins like benzene and stress may affect biological age, with cigarette smoke considered the most significant gerontogen. Researchers advocate for molecular tests to predict toxicity and accelerate aging research.
A University of Alberta researcher has developed a paper-based diagnostic tool to detect deadly food-borne pathogens such as E. coli. The device, slightly larger than a postage stamp, is designed to be extremely portable and self-contained, allowing for daily testing on farms in developing countries.
Researchers at Duke University have developed software that tracks and records infants' activity during videotaped autism screening tests. The program is as good as experts giving the test themselves and better than non-expert medical clinicians and students in training, showing promise in identifying early signs of autism.
A recent NIH study found that high cholesterol levels may impair fertility in couples trying to achieve a pregnancy. Couples with the highest cholesterol levels took longer to get pregnant, while those with acceptable cholesterol levels had faster conception rates.
Researchers developed a new cognitive test that can accurately distinguish between memory impairments caused by very mild Alzheimer's disease and those due to normal aging. The test assesses relational memory abilities and reveals unique impairments specific to Alzheimer's, allowing for more precise diagnosis.
A randomized study found that home testing of obstructive sleep apnea (OSA) followed by initiation of CPAP therapy reduced costs compared to in-lab testing, without compromising clinical outcomes. The study showed significant cost savings of $564 over 2.75 years, making home management a viable option.
A new study suggests that a simple urine test can detect blood clots in patients at risk, offering advantages over existing screening methods. The test evaluates fibrinopeptide B levels in urine, which are released when a thrombosis forms and then cleared by the body.