Articles tagged with Preventive Medicine
A study published in Science Advances found that cannabidiol (CBD) inhibited SARS-CoV-2 infection in human cells and mice, suggesting its potential as a preventative or early treatment for COVID-19. CBD's effects were confined to high purity doses and specific situations.
A recent study published in Science Translational Medicine identified a novel causative gene, BAG5, for dilated cardiomyopathy, a leading cause of heart failure. The researchers found that mutations in this gene can lead to cardiomyopathy and found a potential treatment alternative using adeno-associated viruses (AAV) gene therapy.
Researchers at Boston Medical Center created a new resource to manage long-term heart disease risk after specific pregnancy complications. The review synthesizes recommendations for primary care clinicians to assess and manage risk, focusing on preeclampsia, gestational diabetes, and preterm delivery.
A study published in PNAS found that trust and knowledge about vaccination are stronger predictors of vaccination than Covid-specific factors. Background beliefs and behavior regarding vaccination in general were more than twice as predictive of the change in vaccination as beliefs about the pandemic itself.
A clinical trial of 18,353 adults found no benefit of omega-3 supplements in preventing depression. The study, led by Massachusetts General Hospital and Brigham and Women's Hospital, tested the effect of daily vitamin D and/or omega-3 supplements on depression risk over a median of 5.3 years.
Researchers found that high avocado consumption led to reduced caloric energy intake, lower dairy and meat consumption, and improved fiber and nutrient intake. However, unexpected decreases in calcium and certain minerals were also observed.
A KU study reveals that individuals' political ideologies play a crucial role in shaping their health behaviors during the COVID-19 pandemic. The research, conducted using two surveys and a review of existing data, found that ideology was a significant predictor of health behavior, especially when compared to other factors such as age,...
Researchers found that geriatric cotton rats given ibuprofen cleared RSV more quickly than those without the drug. Ibuprofen improved immune response by lowering aging-related inflammation, suggesting a potential role for the drug in providing lasting immunity against RSV.
The USPSTF has developed strategies to address systemic racism in its recommendations, aiming to promote health equity in preventive services. The new approaches focus on eliminating disparities in healthcare access and outcomes.
A new study found that healthcare providers hold less favorable judgments about patients who inject drugs, leading to potential lack of access to preventive HIV medication. The study highlights the importance of raising awareness and standardizing access to PrEP for all people, regardless of their risk factors.
The USPSTF report examines the intersection of racism and health inequity in preventive services, highlighting existing definitional and conceptual issues. The study aims to improve patient care by addressing these disparities, which have significant implications for health outcomes.
Researchers at Boston University have developed a new online risk prediction model for breast cancer in Black women, suitable for use in primary care settings. The model is well-calibrated and discriminatory accurate, with the highest accuracy for women under age 40.
The USPSTF report describes methods used to identify recommendations with sex or gender components and propose an approach to making recommendations respectful of gender diversity. The task force aims to clarify the populations for which these recommendations should apply.
A new AI-based computer algorithm created by Mount Sinai researchers can identify subtle changes in electrocardiograms to predict heart failure. The algorithm was 94% accurate at predicting healthy ejection fractions and 87% accurate at detecting weakened hearts, offering a promising alternative to traditional diagnosis methods.
A study published in the European Heart Journal found that increasing steps per day, moderate-to-vigorous physical activity, or reducing sedentary time can improve cardiorespiratory fitness. Individuals with higher-than-average activity levels had better fitness regardless of sedentary time spent.
The National Kidney Foundation has released a research roadmap to accelerate innovations in treatment and increase understanding of kidney disease. The report calls for increased funding in preclinical science, genetics, health equity, and implementation science to tackle the most vexing challenges in kidney disease.
Researchers developed a novel machine learning algorithm to identify previously unknown air pollutant mixtures linked to poor asthma outcomes in children. The study found that early exposure to individual and mixed pollutants can lead to longer-term problems with asthma, affecting about seven percent of US children.
Researchers have discovered a genetic mutation called retroCHMP3 that can block the replication of certain viruses like HIV and Ebola by disrupting their ability to exit an infected cell. This finding has the potential to lead to the development of new medical interventions against these deadly diseases.
The VCU Massey Cancer Center has established a Translational Research Center in Lung Cancer Disparities (TRACER) to address racial disparities in lung cancer. TRACER will investigate the interaction between stress, smoking, and gene expression to raise lung cancer risk in Black men.
A first-of-its-kind global study links short-term exposure to wildfire-related fine particulate matter to increased all-cause, respiratory, and cardiovascular mortalities. The research found that over 33,500 deaths annually are directly attributable to wildfire pollution in cities worldwide.
A study found that over 50 US localities allow indoor cannabis smoking lounges, exposing customers and employees to secondhand cannabis smoke. Most laws do not require smoke-free environments or effective ventilation, putting public health at risk.
A new study found that non-Hispanic Black and Mexican American adults are diagnosed with type 2 diabetes at an average age of 46-47 years old, four to seven years earlier than non-Hispanic white adults. Preventive measures such as nutrition counseling and physical-activity programs can prevent or delay the onset of diabetes.
A new TB prevention regimen for HIV-positive individuals has shown promising results, with 90.4% completing the three-month course compared to 50.5% of those on a six-month daily treatment. The study suggests that this shorter approach is as safe and effective as the standard treatment.
The International Vaccine Institute (IVI) has initiated a Phase II/III clinical trial for the Bharat Biotech Chikungunya vaccine candidate BBV87, evaluating its safety and immunogenicity in healthy adults across five countries. The study aims to develop an affordable vaccine with the aim of achieving WHO prequalification.
A randomized trial found that a shorter course of rifapentine-isoniazid therapy resulted in significantly higher treatment completion rates compared to a longer daily course. The findings suggest that this regimens can be more effective for preventing tuberculosis disease in individuals with HIV, particularly in high-transmission areas.
A new epidemiology study reveals crucial trends in HIV/AIDS progression in China from 1990 to 2017. The study highlights the need for effective strategies to reduce mortality rates, especially among men, by intensifying targeted efforts including early identification and diagnosis, high-quality treatment services, and patient retention.
A Korean population-based cohort study found that cancer, particularly multiple myeloma and leukemia, is associated with an increased risk of kidney failure. The study included approximately 825,000 patients with cancer compared to twice as many without cancer, matched on other characteristics.
The US Preventive Services Task Force (USPSTF) has made a recommendation to screen for gestational diabetes in asymptomatic pregnant women at 24 weeks or later. The organization concludes that the current evidence is insufficient to make a recommendation about screening before this time frame.
A new study found that only 7% of patients who switched from Truvada to Descovy had a documented clinical reason for doing so, highlighting the need for cost-effective PrEP options. The significant price difference between the two medications may be a major barrier to broad and equitable PrEP use in the US.
A comprehensive review of keto diets found potential health risks, including increased heart disease risk, cancer risk, and adverse effects on pregnant women and kidney patients. For most people, the possible long-term benefits of a keto diet are outweighed by its potential drawbacks.
The COVID-19 pandemic has likely led to an increase in falls among older adults due to decreased physical activity, worsened physical conditioning, and heightened fear of falling. This is a pressing concern as falls can result in significant injuries, particularly among this age group.
The American Academy of Family Physicians is investigating an 'educational' session promoting dairy products linked to increased risk of prostate cancer and other diseases disproportionately affecting African Americans. The Physicians Committee for Responsible Medicine filed a complaint, citing standards set by the Accreditation Counci...
A new study found that lower-wealth volunteers experience even greater health gains from volunteering compared to higher-wealth volunteers. Volunteering enhances self-reported health and reduces depressive symptoms regardless of wealth status.
Major points of progress in women's health since the 1970s include reproductive health advances, improvements in overall well-being throughout life, reduced mortality rates for cardiovascular and cancer diseases in women. Clinical research has improved understanding of conditions disproportionately affecting women, such as autoimmune d...
A new study reveals that up to 24 percent of esophagectomy patients can develop Venous Thromboembolism (VTE), leading to significant morbidity and mortality. The six-month mortality rate for patients with VTE was found to be 17.6 percent, compared to 2.1 percent for those without.
A new set of guidelines developed by AATS and ESTS recommends a 30-day course of Venous Thromboembolism (VTE) prophylaxis post-discharge for patients undergoing surgical resection for lung or esophagus cancer. The guideline panel endorsed by American Society of Hematology and International Society on Thrombosis and Haemostasis found th...
A study published in the Journal of Public Health Management and Practice finds that the number of preventive medicine physicians is not likely to match population needs in the US. The specialty is aging, with nearly half of physicians over 60 years old, and new trainees are scarce.
A CDC compilation of scientific research found telephone call centers, or quitlines, to be a successful intervention for smoking termination. The study highlights the importance of call centers as an essential population-level tool in tobacco control, particularly among high-risk populations.
A large-scale study found that early detection and treatment of rheumatic heart disease (RHD) through echocardiographic screening and antibiotic prophylaxis significantly reduced RHD prevalence by two-thirds in schools. This approach is an effective strategy to control RHD in endemic regions.
COVID-19 patients are at increased risk of pulmonary thromboembolism due to endothelial injury, activated platelets, cytokine storms, and suppressed fibrinolytic systems. Early prophylaxis, antiviral therapy, and supportive treatment can mitigate this complication.
A study by Octapharma at ASH found that high-dose Octagam 10% IVIg significantly improved hypoxia and reduced hospital length of stay in COVID-19 patients with pneumonia. A larger multicenter study is underway to determine if the therapy can slow or stop respiratory deterioration.
A new study published in PLOS Medicine suggests that the symptomatic case fatality ratio (sCFR) and infection fatality ratio (IFR) are better measures for monitoring COVID-19 epidemics than the commonly used case fatality ratio (CFR). The researchers applied a computational model to Hubei province, China, and six European regions, find...
Children with severe hemophilia A who receive early prophylaxis are less likely to have joint damage in young adulthood than those who begin treatment later. However, prophylaxis does not fully prevent joint damage.
Research found substituting prolonged sedentary time with sleep was associated with lower stress and improved mood. Light physical activity, such as walking around the home office, also provided benefits for up to a year, including improved mood and lower BMI.
Experts in Ayurveda and yoga propose using these traditional practices to boost immune function and prevent COVID-19 infection. The authors discuss various methods, including local prophylaxis with herbal drinks and steam inhalation, as well as systemic approaches focusing on diet, sleep, and mental relaxation.
A new study published in the American Journal of Preventive Medicine found that three-quarters of teen vapers report using nicotine, marijuana, or multiple substances. The study analyzed data from over 14,000 teens and revealed significant associations between cigarette smoking intensity and vaping behavior.
A new study from Northwestern University shows that a free online training tool can significantly boost scientists' knowledge of team science and increase their self-confidence. The COALESCE tool has been validated by research to help scientists collaborate smoothly, reducing disputes over data access and authorship.
A new study found that giving all women a single dose of preventative antibiotics after childbirth involving forceps or vacuum extraction could prevent almost half of maternal infections. The trial, involving 3,420 women, suggests that this simple intervention could reduce antibiotic use by 17% and save the NHS £52.60 per woman.
A new study identifies medical conditions that increase the risk of self-directed violence among teens and young adults visiting emergency departments. These conditions include epilepsy, seizures, multiple pain visits, syncope, vomiting, and dental complaints, highlighting the importance of EDs in suicide prevention.
Researchers found that antibiotic prophylaxis regimens are less effective at preventing surgical site infections following colorectal surgery. The efficacy of antibiotic prophylaxis has remained unchanged for other procedures like appendectomy and cesarean section.
A study found a concerning decrease in antibiotic prescribing for high-risk dental patients, despite an increase in infective endocarditis cases. The research supports the American Heart Association's recommendation to continue prophylaxis for those at high-risk of IE.
A high level of fitness in midlife is associated with a lower risk of depression after age 65 and a lower risk of cardiovascular death, including after a diagnosis of depression. Longitudinal studies can inform health care professionals about the importance of considering fitness as part of overall preventive care.
A new study by USC researchers found that high school, middle school, and elementary school students in the US are using JUUL vaporizers to get hooked on nicotine. The discreet devices are being used undetected on school grounds, with over 1 in 25 tweets mentioning their use.
A new study examines the potential health impacts of Republican and Democratic tax proposals on the US population's health. The research suggests that only policies raising top federal income tax rates and redistributing tax revenue to lower-income households can significantly reduce mortality rates, with estimated reductions ranging f...
A large-scale study found that patients who receive antibiotics before certain types of low-risk operations have the same risk for developing antibiotic-resistant infections as those who don't. The study analyzed data from over 22,000 patients and found no association between prophylactic antibiotic use and postoperative antibiotic res...
A European Centre for Disease Prevention and Control expert opinion supports the use of neuraminidase inhibitors in treating and preventing influenza. The most vulnerable individuals, such as the elderly and those with compromised immune systems, are particularly eligible for treatment and prophylaxis.
Researchers at Queen Mary University of London secured £8.6m in grants to develop and implement salt reduction programs in China, aiming to prevent thousands of deaths from stroke and heart disease. A new Global Health Research Group will focus on improving mental health interventions in low-income countries.
Activity monitors have moderate validity compared to other measures of daily energy expenditure and physical activity, leaving out important information such as intensity of effort. Current accelerometers perform well at moderate walking speeds but struggle under other conditions.
The use of computerized clinical decision support systems improves prophylaxis for venous thromboembolism among surgical patients, reducing the risk of developing a blood clot by up to 50 percent. Computerized systems also increase the rate of appropriate treatment ordering.
A new NIH-funded study found that in underserved populations, parents' physical activity levels directly correlate with their preschoolers' activity levels. The research suggests interventions could focus on helping parents model an active lifestyle for their children to combat obesity. Low-income and ethnic minority families are dispr...