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Most Americans still get nicotine wrong

A new study found that many Americans incorrectly think nicotine is inherently deadly, leading to misconceptions about the dangers of smoking. The researchers discovered that changing the wording of questions can significantly impact the percentage of people answering correctly, from 10% to 80%.

SourceRutgers University·JournalNicotine & Tobacco Research·TypeSurvey·DateDec 18, 2025

Disappointment alters brain chemistry and behavior

A mouse study by Okinawa Institute of Science and Technology researchers has found that acetylcholine release is essential for breaking habits and enabling new choices to be made. The study's findings may help understand diseases such as Parkinson's disease, addiction, and obsessive-compulsive disorder.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalNature Communications·TypeExperimental study·DateDec 17, 2025

Medical cannabis program reduces opioid use

A new study published in JAMA Internal Medicine found that adults with chronic pain who used medical cannabis had a 22% reduction in opioid use. The study, led by researchers at Albert Einstein College of Medicine, suggests that supervised use of medical cannabis can relieve chronic pain and reduce reliance on prescription opioids.

SourceAlbert Einstein College of Medicine·JournalJAMA Internal Medicine·TypeRandomized controlled/clinical trial·DateDec 8, 2025

Brain circuit controlling compulsive behavior mapped

A new study identifies a brain circuit that can drive repetitive and compulsive behaviors in mice, even when natural rewards are available. The researchers used optogenetics to activate the circuit and induce negative states in mice, leading to prioritization of repetitive behaviors over natural needs.

SourceKarolinska Institutet·JournalScience Advances·TypeExperimental study·DateNov 21, 2025

As ‘California sober’ catches on, study suggests cannabis use reduces short-term alcohol consumption

A new study found that smoking marijuana can temporarily cut down how much people drink, with participants reducing their alcohol intake by 19-27% when using cannabis. However, the researchers caution that more study is needed to determine long-term effects and potential risks of cannabis use.

SourceBrown University·JournalAmerican Journal of Psychiatry·TypeRandomized controlled/clinical trial·DateNov 19, 2025

Edging, tab-jumping, and more: Researchers identify behavioral markers of problematic pornography use

A recent study investigated problematic pornography use (PPU) among men and found that increased time spent on pornography was closely associated with other intensity indicators. Binge sessions, tab-jumping, and edging were strongly linked to PPU, suggesting that digital novelty plays a central role in usage patterns.

SourceD'Or Institute for Research and Education·JournalAddictive Behaviors·DateNov 18, 2025

Study finds longer, more consistent addiction medication use among youth sharply lowers risk of overdose, hospitalization

Adolescents and young adults who stayed on medication for at least a year had lower risks of opioid overdose and hospitalization compared to those who discontinued early or took it inconsistently. Consistent, year-long use likely provides the greatest protection against overdose and other serious outcomes.

SourceMass General Brigham·JournalPEDIATRICS·TypeData/statistical analysis·DateNov 18, 2025

Increased avoidance learning in chronic opioid users

This study confirms the role of negative reinforcement in chronic opioid use, contributing to addiction development. The findings suggest that this mechanism is present even after regular opioid use, highlighting potential for more effective prevention and treatment strategies.

SourceJAMA Network·JournalJAMA Psychiatry·DateNov 6, 2025

Hollings researcher co-leads AACR subcommittee calling for nicotine limits

The American Association for Cancer Research (AACR) endorses a federal policy that sets a maximum nicotine product standard, limiting nicotine levels in combustible cigarettes and related tobacco products to 0.7 mg/g. This reduction aims to make cigarettes minimally or non-addictive, striking at the chemical that keeps people hooked. E...

SourceMedical University of South Carolina·JournalClinical Cancer Research·TypeLiterature review·DateNov 6, 2025

Drinking for two? Prenatal alcohol exposure rewires the brain and fuels compulsive behavior, new study finds

A new study reveals how prenatal alcohol exposure impairs key brain cells and circuits, leading to cognitive inflexibility and increased risk of compulsive alcohol use. Researchers identified a specific brain cell affected by early alcohol exposure, providing a clear target for developing more effective treatments of FASD.

SourceTexas A&M University·JournalNeuropharmacology·DateOct 28, 2025

Drinking through the generations

A new study by Flinders University found that abstention from alcohol is on the rise, particularly among younger cohorts, with Generation Z nearly 20 times more likely to choose not to drink compared to Baby Boomers. The study suggests a clear generational shift, with declining weekly alcohol consumption and changing social norms drivi...

SourceFlinders University·JournalAddiction·TypeMeta-analysis·DateOct 7, 2025

CU Anschutz School of Medicine researchers identify new method for treating alcohol use disorder

Researchers found that tolcapone increases behavioral control in individuals with AUD by activating the prefrontal cortex, which is consistent with the drug's effects on dopamine levels. The study suggests a new mechanism for treating AUD beyond current medications that target the brain's reward system.

SourceUniversity of Colorado School of Medicine·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·DateSep 30, 2025

Many older adults – especially Gen X women – show signs of addiction to ultra-processed foods

A study found that 21% of Gen X women and 10% of men meet criteria for ultra-processed food addiction, with a higher prevalence in older women. The study highlights the link between ultra-processed foods and risk of chronic disease and premature death, particularly among those who perceive themselves as overweight.

SourceMichigan Medicine - University of Michigan·JournalAddiction·TypeSurvey·DateSep 29, 2025

Small rewards lead to big wins for saving veterans’ lives

A new study suggests that contingency management, which uses cash or gift certificate prizes as incentives, can reduce the risk of death among veterans with stimulant use disorder. The study found a 41% lower risk of death in veterans who received contingency management care compared to those who didn't.

SourceMichigan Medicine - University of Michigan·JournalAmerican Journal of Psychiatry·TypeData/statistical analysis·DateSep 10, 2025

Study reveals how a popular fentanyl additive affects breathing and heart rate

A new U-M study found that xylazine does not amplify the decrease in breathing rate caused by fentanyl use, but reduces heart rate more than fentanyl. This reduction in heart rate may be a more important driver of increased overdose risk, highlighting the need for further research into polysubstance use involving opioids.

SourceMichigan Medicine - University of Michigan·JournalJournal of Pharmacology and Experimental Therapeutics·DateAug 29, 2025

Study proposes new, more personalized methadone restart approach for opioid use disorder

A new study from the University of Colorado Anschutz Medical Campus introduces a more individualized approach to restarting methadone treatment for people with opioid use disorder. The findings suggest that tailoring methadone doses to each patient's unique circumstances can improve care without compromising safety.

August Issues of APA journals feature new research on psychiatric genetics, telehealth prescribing of controlled substances, mental health advocacy, and more

The latest American Psychiatric Association journal issues feature groundbreaking research on psychiatric genetics, exploring the role of genetics in mental health. Additionally, studies examine the effectiveness of telehealth prescribing for controlled substances and mental health advocacy efforts to drive policy change.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateAug 4, 2025

US adolescents with cannabis use disorder failing to complete rehabilitation

A recent study by Florida Atlantic University found that US adolescents with cannabis use disorder have low treatment completion rates, ranging from 34.2% to 33.8%. The most common reasons for not completing treatment were dropping out, transferring facilities, and being terminated. Adolescents who began using cannabis at a younger age...

SourceFlorida Atlantic University·JournalPediatric Reports·TypeData/statistical analysis·DateJul 22, 2025