A new study published in JAMA Network Open found that combining cannabis edibles and alcohol worsens driving impairment compared to consuming either substance alone. The research highlights the urgent need for wider public education about augmented effects from co-use and improved roadside detection methods.
A new study published in the Journal of the American Heart Association found that methamphetamine use accounted for nearly 15% of heart attacks in a northern California study. People who suffered meth-related heart attacks were often young- to middle-aged men without traditional heart disease risk factors, highlighting the need for spe...
Research suggests that vaping is associated with increased odds of quitting smoking, but this relationship may not be true for everyone. Daily vape use was a stronger predictor of successful cessation than intermittent or no use.
Visitors to a California region with numerous substance use disorder treatment centers experience higher levels of overdose, particularly out-of-state individuals. The study suggests that the industry's lack of oversight and predatory practices contribute to this hotspot.
Adolescents who follow social media tipsters report higher gambling intention and increased frequency. The study highlights the need for stronger regulation of tipster-related marketing and media literacy programmes to address persuasive strategies and improve risk awareness.
A study using the Meta Ad Library found that gambling companies are reaching young men on social media at more than double the rate of women, with 91% of ads targeting men only. The age group most exposed to advertising was 25-34-year-olds, who accounted for over a third of all unique accounts reached.
Researchers identified three main patterns of AI addiction: role-playing and fantasy worlds, emotional attachment to chatbots as close friends or partners, and constant information-seeking. These patterns led to disruptions in daily life, including anxiety, stress, and negative impacts on work, studies, and relationships.
Social media use has been linked to psychological distress and impaired functioning in some people, but the impact varies widely depending on how and why it's used. Researchers are debating how to measure social media addiction and need more rigorous studies to determine whether it should be classified as a clinical disorder.
A recent study found that academic burnout is associated with increased internet gaming and depression in Chinese adolescents. The study highlights the importance of targeted prevention strategies, including mental health check-ups, counseling sessions, stress management programs, and attentional bias modification training.
Researchers found that introducing new objects in a nonsocial environment reduced fentanyl intake over time and helped rats stop seeking the drug faster. Enriched environments also showed lower levels of stress hormones, linked to relapse in standard conditions.
A Drexel University study found that teens are concerned about their attachment to AI chatbots, using them for emotional support and entertainment. The study suggests that these interactions can evolve into addiction-like behavior, affecting their lives offline.
Research from the University of Kansas reveals that chronic pain is linked to higher rates of smoking and vaping, particularly among those with more severe pain. The study's findings highlight the need for targeted interventions addressing both chronic pain and tobacco use.
Recent Medicaid expansions led to a significant increase in the use of buprenorphine, a medication used to treat opioid use disorder. The study found that these expansions resulted in population-level increases in treatment uptake, despite ongoing fatal overdose trends.
A new study highlights how geography and regulations limit methadone access in US jails, with over half of facilities located more than a 30-minute drive from the nearest opioid treatment program. This distance creates logistical challenges for providing this lifesaving medication to incarcerated individuals.
Researchers found a direct line of communication between the brain's stress centers and decision-making regions, which is disrupted by alcohol. This disruption can lead to unhealthy habits and relapse during recovery from alcohol use disorder.
A new analysis of existing studies found that nicotine e-cigarettes consistently help adults quit smoking, with quit rates approximately 20-40% higher than traditional nicotine replacement therapies. However, the effectiveness of e-cigarettes may be linked to sensory cues beyond just nicotine delivery.
A new overview of systematic reviews found that nicotine-containing e-cigarettes are more effective for smoking cessation than other interventions. The review also identified gaps in current evidence, including the need for high-quality studies on cytisine and bupropion.
A study published in Frontiers found that young people with attachment anxiety and difficulties identifying emotions are more susceptible to short video addiction. Mental training, such as mindfulness and attention regulation, can help prevent this addiction by strengthening emotional awareness and cognitive regulation.
Researchers analyzed genetic data from over 2.2 million individuals to understand how genes shape vulnerability to alcohol, tobacco, cannabis, and opioid use disorders. They found that genetic risk operates along two main pathways: one related to brain wiring and the other specific to each substance.
Lawrence Toll has been named a senior member of the National Academy of Inventors for his pioneering work on pain pathways, reward systems, and potential treatments. His research focuses on identifying new drug targets and therapeutic strategies to combat chronic pain and addiction.
Researchers analyzed Oregon Medicaid case data and found that severe burns requiring hospital-level care are a growing threat in the overdose epidemic. People who smoke drugs like fentanyl and methamphetamine account for most of these cases, with butane torches posing a significant risk due to locking mechanisms.
A comprehensive review of 54 randomized controlled trials found no evidence that medicinal cannabis is effective in treating anxiety, depression, or PTSD. However, the study suggests that medicinal cannabis may be beneficial for certain conditions, such as reducing seizures associated with epilepsy and managing pain.
A new study found that people are more likely to place bets during weeks with major sporting events when they believe their friends are doing the same. Researchers say early intervention is key to preventing harmful betting patterns, as it can be associated with depression, anxiety, and increased substance use. The study, led by Univer...
Researchers propose a new measure for recovery from substance use, recognizing incremental progress, to reduce stigma and improve quality of life. The study found strong associations between proportion of remission and quality-of-life measures, suggesting a paradigm shift in how recovery is measured.
A large US study published in The BMJ found that GLP-1 receptor agonists used to treat type 2 diabetes and obesity may also help lower the risk of addiction to various substances. The study associated GLP-1 receptor agonists with reduced risks of adverse outcomes such as overdoses and drug-related emergency department visits and deaths...
Researchers found that GLP-1 medications are effective at reducing the risk of developing substance use disorders across all major addictive substances, including a 14% reduced risk for developing any substance use disorder. The study also showed significant reductions in severe harm, including overdose and death, among patients with p...
Research at Michigan State University reveals how cocaine addiction is notoriously difficult to treat due to its impact on brain function. The study found that chronic cocaine use changes brain activity, particularly in the hippocampus and reward centers, leading to compulsive behavior.
A massive Swedish study of over 2 million individuals reveals that genetic risk for mental illness is far less disorder-specific than clinicians have assumed. Schizophrenia shows the highest genetic specificity, while drug use disorder has a much lower specificity, scattering its genetic risk across multiple conditions.
A new study using rats found that a specific brain region, the anterior insula, is more active during actions related to alcohol consumption. This bias in decision-making may be involved in prioritizing alcohol over other rewards, potentially shedding light on the neural underpinnings of alcohol use disorders.
A new study based on extensive data from Swedish school surveys found that changes in average cannabis use among adolescents are reflected across the entire group. The distribution of cannabis use has remained highly stable over time, with increases or decreases occurring in parallel across all user groups.
The University of Cincinnati's new UC/UC Health Addiction Center aims to improve addiction prevention and treatment outcomes through innovative research, enhanced clinical services, and education excellence. The center will coordinate activities across five UC colleges and 12 departments to foster interdisciplinary solutions.
A meta-analysis of longitudinal studies found that broad spiritual practices, such as attending religious services and meditation, were associated with a 13% reduced risk of hazardous drug and alcohol use. This reduction was greater (18%) among individuals attending religious services at least once per week.
A new theory asserts that associative learning depends less on repetition and more on time passing between rewards, explaining why students who cram don't perform well. The study's findings could shift the way we look at learning and addiction, potentially speeding up artificial intelligence by borrowing from this new approach.
A new study from King's College London and the University of Exeter found that ketamine's therapeutic benefits for people with alcohol use disorder may not be linked to its psychoactive effects. Instead, other factors such as brain network alterations and neural connections may play a role in the treatment's success.
A Brazilian study analyzing 4,280 adolescents and their guardians found that parental attitudes play a significant role in preventing alcohol and drug use among young people. The 'authoritative' parenting style, which combines acceptance and monitoring, is the most effective in mitigating the risk of repeated consumption patterns.
Research found that people experiencing economic disadvantages are more likely to smoke cigarettes, have higher levels of tobacco addiction, and find it harder to quit. Electronic cigarettes were the most common aid to help people quit, but those who rented or owned their houses had lower odds of quitting successfully.
Researchers found that patients with substance use disorder received life-saving treatments only when addiction consult services were involved. Fentanyl use was associated with dramatically worse visual outcomes, highlighting the importance of addressing underlying conditions alongside acute medical problems.
Chronic alcohol consumption alters endocannabinoid gene expression in reward- and decision-related brain regions, offering insights into addiction biology. This study reveals changes in CB1 and CB2 receptor genes, as well as GPR55 and FAAH enzymes, potentially leading to targeted therapeutic strategies.
A new study found that removing legal barriers to cannabis use may reduce daily opioid use and lower the risk of opioid-related overdoses among people who inject drugs. US states that legalized recreational cannabis saw a 9-to-11-percentage-point decline in daily opioid use among this population.
A new national survey found that nearly three-quarters of clinicians encounter obstacles when starting buprenorphine treatment for patients using fentanyl. Researchers emphasize the need for evidence-based guidelines to initiate buprenorphine in light of more potent drugs.
A new study from Tufts University finds that regular family dinners can help prevent substance use among adolescents with low to moderate levels of adverse childhood experiences. However, for those with severe stressors, more targeted approaches like mental health support are needed.
The latest APA Journal issues explore the intersection of neuroplasticity and substance use, as well as emerging trends in outpatient psychotherapy. The American Psychiatric Association's flagship journals offer insightful research on mental health topics.
A study found that prenatal alcohol exposure changed aspects of the dopamine system in rhesus monkeys, influencing how quickly they drank alcohol in adulthood. The researchers also discovered individualized neuroadaptive responses to drinking, which may promote the transition to alcohol use disorder.
Researchers at the University of Delaware discovered a neural network in fruit fly brains that assigns value to specific foods minute by minute, integrating context, internal state, and past experience. This breakthrough study offers insights into the origins of eating disorders and addiction.
Research identifies reduction in recovery focus as most prevalent and potent contributor to long-term relapse, emphasizing the importance of ongoing monitoring and proactive interventions. The study highlights the need for integrated biopsychosocial disease-management models to address complex relapse risk factors.
Researchers are developing brain-based interventions to treat co-occurring disorders, including rTMS and deep brain stimulation for addiction. The Brain & Behavior Research Foundation awards grants to fund research on mental illness treatments.
A UH psychologist's study finds that anxiety sensitivity and pain-related anxiety are linked to mental health problems and clinically significant alcohol use among survivors of traumatic sexual assault. The investigation highlights the importance of addressing both types of anxiety in reducing the risk of lifelong challenges.
Smokers who successfully quit with e-cigarettes and continue vaping may be reducing their risk of relapse. The study found that abstainers in the e-cigarette arm were less likely to relapse than those in the nicotine replacement therapy (NRT) arm.
A new study by the University of Bath and Tampere University found that individuals exposed to problem gambling within family or friend networks are more likely to develop their own gambling issues. Strong family relationships significantly reduce this risk, whereas friendships do not provide a comparable protective effect.
A new study found that varenicline, a medication used to quit smoking, can help men with cannabis use disorder reduce their cannabis use. However, the same treatment showed no significant effect on female participants. Women who received varenicline reported higher withdrawal and craving scores and lower medication adherence compared t...
A new study in NC found that many residential substance-use service providers require patients to engage in unpaid labor, restricting access to evidence-based treatment. Providers with labor requirements are less likely to offer recommended treatment and more likely to operate without a state license.
A preclinical study shows that cannabidiol restores emotional behavior, reduces alcohol-related vulnerability, and reverses gut microbiota alterations caused by prenatal alcohol exposure. Female mice particularly benefited from CBD treatment, which normalized their emotional alterations and eliminated vulnerability to alcohol addiction.
A study funded by the National Cancer Institute aims to test a low-cost intervention using future-focused thoughts to help people quit smoking. The project will examine the effectiveness of episodic future thinking in reducing impulsivity and promoting healthier choices.
Smartphone apps based on psychological theories are 3 times more effective than minimal support in helping people quit smoking long-term. The apps improve sustained abstinence rates when combined with traditional interventions or pharmacotherapy.
Research found that prolonged heavy drinking induces neuroinflammation, promoting negative emotional states lasting for weeks into abstinence. Inhibiting proinflammatory microglia activation during alcohol exposure blocks the development of anxiety and fear memory.
A new protocol models alcoholism in mice and shows that stimulating the FGF21-oxytocin-dopamine system with rare sugars can reduce alcohol consumption. The researchers believe that this system may play a role in regulating subconscious information processing, leading to effective dietary therapy for reducing over-drinking.
Researchers propose threshold levels for safe cannabis use, aiming to guide consumption and reduce harm. The recommended limit is 8 THC units per week, above which the risk of developing cannabis use disorder increases.
University of Florida researchers have identified a new potential target for treating methamphetamine addiction by modulating the immune system. Using immune-modulating medicines, they were able to mitigate the effects of TNF and dopamine release in mouse brain specimens.
New research suggests that mobile health interventions tailored to individual needs can reduce harms associated with heavy drinking and cannabis use. Studies demonstrate the effectiveness of personalized feedback and protective behavioral strategies in reducing substance use risks, paving the way for innovative digital interventions.
A new study of over 32,000 US Veterans found that longer treatment with medications for opioid use disorder is associated with a greater probability of short- and medium-term survival. The benefit continues to increase at least for four years of ongoing treatment.