Articles tagged with Addiction
A new study reveals a strong connection between social media addiction and poor sleep quality among high school graduates in Bangladesh. Higher levels of social media addiction were closely associated with poorer sleep quality, particularly in female participants.
The University of Houston is part of a statewide effort to fight the opioid epidemic by investigating opioid use disorder among people living with HIV in Harris County. Researchers aim to integrate prevention methods, including Screening, Brief Intervention, and Referral to Treatment (SBIRT), into treatment for those affected.
This study confirms the role of negative reinforcement in chronic opioid use, contributing to addiction development. The findings suggest that this mechanism is present even after regular opioid use, highlighting potential for more effective prevention and treatment strategies.
The American Association for Cancer Research (AACR) endorses a federal policy that sets a maximum nicotine product standard, limiting nicotine levels in combustible cigarettes and related tobacco products to 0.7 mg/g. This reduction aims to make cigarettes minimally or non-addictive, striking at the chemical that keeps people hooked. E...
A US study found that nicotine vaping nearly doubled among adolescents who vaped between 2020 and 2024, with a significant increase in daily users struggling to quit. The researchers aimed to understand the 'hardening' of youth vapers, describing a worsening addiction pattern.
Researchers discover molecules that can rewire G protein-coupled receptor signaling, turning busy receptors into precision tools. The findings hold promise for new treatments with fewer side effects.
A new study reveals that laws restricting pain clinics, or 'pill mills,' where opioids were often prescribed, reduced risky opioid use by 5 percent. Enacting such laws near the onset of the crisis in the 1990s could have reduced risky use by 30 percent over time.
A new study reveals how prenatal alcohol exposure impairs key brain cells and circuits, leading to cognitive inflexibility and increased risk of compulsive alcohol use. Researchers identified a specific brain cell affected by early alcohol exposure, providing a clear target for developing more effective treatments of FASD.
Inpatient care offers a range of supports, from reducing drug use to abstinence, but access is challenging due to long wait-lists. The RE-AIM framework helps evaluate the effectiveness of bed-based care and its capacity to meet population needs.
A study published in the Journal of Neuroscience found that mutations in the CHRNA3 gene are associated with lowered sensitivity to alcohol and delayed avoidance behavior. This suggests that normal function of the chrna3 gene helps control alcohol exposure, leading to individual differences in alcohol sensitivity.
A Cochrane review suggests that switching to oral nicotine pouches from smoking reduces exposure to harmful substances, but the evidence is not yet clear on whether they can help people quit smoking. The review also notes that other nicotine products, like patches and gums, are beneficial for quitting smoking.
A study by Ohio State University found that more than 15% of undergraduates and 11% of graduate students had tried nicotine pouches. Fraternity members reported the highest rates, with 41% saying they'd tried a pouch like Zyn.
A new study suggests that psychological cessation fatigue is a key factor in smoking relapse among ex-smokers. The study found that exhaustion from constantly trying to remain a non-smoker can overwhelm coping skills and motivation, leading to increased risk of relapse.
The analysis explores how reduced fentanyl production costs affect the structure and conduct of the illegal opioid supply industry. It also assesses potential consequences for drug law enforcement organizations, finding modest declines in expenditures and income-generating crime.
A large genetic study found associations between cannabis use and various traits, including psychiatric disorders, cognitive measures, and physical health problems. The study identified two genes, CADM2 and GRM3, linked to lifetime cannabis use and frequency of use.
A new study by Flinders University found that abstention from alcohol is on the rise, particularly among younger cohorts, with Generation Z nearly 20 times more likely to choose not to drink compared to Baby Boomers. The study suggests a clear generational shift, with declining weekly alcohol consumption and changing social norms drivi...
Researchers found that tolcapone increases behavioral control in individuals with AUD by activating the prefrontal cortex, which is consistent with the drug's effects on dopamine levels. The study suggests a new mechanism for treating AUD beyond current medications that target the brain's reward system.
Recent federal cuts to research grants and funding have threatened efforts to combat tobacco usage and health disparities in the US. The elimination of key offices, such as the Office of Smoking and Health, will likely result in reduced access to tobacco prevention and cessation resources.
Deaths due to ketamine use increased twenty-fold between 1999 and 2024, with polydrug settings dominating cases. The study highlights a shift towards older, disadvantaged individuals as primary users, raising questions about single-substance policies.
A global study found that children under 14 years old lose nearly 8.45 million years of healthy life due to second-hand smoke exposure. The study, presented at the European Respiratory Society Congress, highlights the disproportionate burden on low-socio-economic regions.
A study found that 21% of Gen X women and 10% of men meet criteria for ultra-processed food addiction, with a higher prevalence in older women. The study highlights the link between ultra-processed foods and risk of chronic disease and premature death, particularly among those who perceive themselves as overweight.
A study found that people whose fathers began smoking at age 15 or younger show signs of faster biological aging compared to chronological age. This accelerated aging is linked to a higher risk of diseases such as cancer, arthritis, and dementia. The researchers call for stronger efforts to prevent tobacco use in teenagers.
A new study at Hebrew University of Jerusalem found that Israeli men with emotional regulation difficulties were more likely to develop gambling problems after the October 7 attacks. Gambling became a coping mechanism for fear, grief, and uncertainty during the war.
Over-the-counter naloxone sales peaked in September 2023 but declined rapidly due to high costs. Despite efforts to increase access, the medication's sales remained limited compared to prescription and free distribution programs.
A new study suggests that contingency management, which uses cash or gift certificate prizes as incentives, can reduce the risk of death among veterans with stimulant use disorder. The study found a 41% lower risk of death in veterans who received contingency management care compared to those who didn't.
A new University of Michigan study found that between 2000 and 2023, 38,429 children in Michigan experienced a parental death due to suicide, homicide, overdose or other substance-related death, with stigmatized deaths increasing from 28% to 42%. The study aims to provide bereavement services to the most affected areas.
A new U-M study found that xylazine does not amplify the decrease in breathing rate caused by fentanyl use, but reduces heart rate more than fentanyl. This reduction in heart rate may be a more important driver of increased overdose risk, highlighting the need for further research into polysubstance use involving opioids.
A new study from the University of Colorado Anschutz Medical Campus introduces a more individualized approach to restarting methadone treatment for people with opioid use disorder. The findings suggest that tailoring methadone doses to each patient's unique circumstances can improve care without compromising safety.
Researchers at UC San Diego and NIDA developed a new biochemical approach to combat addiction by custom engineering ion channels to be activated by cocaine, breaking the positive feedback loop. This approach could lead to gene therapies for cocaine addiction that preserve enjoyment of regular activities.
Dr. Harriet de Wit's groundbreaking research bridges animal and human drug studies, demonstrating that MDMA enhances feelings of social connectedness and challenging addiction treatment strategies. Her discoveries have profound implications for treating trauma-related disorders globally.
A study at the University of North Carolina Chapel Hill found that brain immune cells, called microglia, drive drug craving by stripping away support structures in astrocytes. Blocking this process reduces relapse behaviors and may help reduce risk of relapse in people recovering from addiction.
A new study from Columbia University Mailman School of Public Health finds that punitive laws are largely ineffective and may actually harm those they aim to protect. Prosocial laws, on the other hand, prioritize access to care and harm reduction, recognizing the complex nature of substance use.
A recent study has consistently linked e-cigarette use to a higher risk of cigarette smoking and various health concerns in young people. The review found that vaping often precedes smoking and can lead to increased frequency and intensity of smoking, as well as associated risks such as asthma and depression.
A study investigated approach/avoidance tendencies in male AUD patients through a gait initiation task, using posturography. The findings suggest that analyzing micromovements and reaction times may help predict if individuals will relapse following treatment.
Adults who quit smoking were more likely to achieve sustained remission of substance use disorder symptoms. The analysis found a 42% greater odds of recovery when quitting smoking was combined with addiction recovery efforts.
Researchers at Emory University developed two affordable programs to prevent youth substance misuse: Connect Kits for Family Action and Connect Brief Intervention. A randomized trial found that these programs reduced alcohol and other substance use among high school students in rural Oklahoma.
The latest American Psychiatric Association journal issues feature groundbreaking research on psychiatric genetics, exploring the role of genetics in mental health. Additionally, studies examine the effectiveness of telehealth prescribing for controlled substances and mental health advocacy efforts to drive policy change.
A nationwide study found that alcohol withdrawal syndrome significantly increases risks of complications and longer hospital stays after major surgery. Proactive screening and multidisciplinary care can help prevent such complications.
A national study found that healthcare providers exhibit varying levels of stigma towards patients with substance use disorders (SUD), particularly for opioid and stimulant use. This stigma leads to missed opportunities for care and is often embedded in clinical encounters.
Research from UCLA Health Sciences found that individuals with substance use disorders are at a higher risk of unplanned hospital readmissions. Specifically, those with opioid use disorder had the highest 30-day readmission rates.
A specific 'anti-reward' brain circuit becomes hyperactive during cocaine withdrawal, driving discomfort and pushing users back toward the drug. However, this circuit may also serve as a protective mechanism, potentially helping to develop new therapies targeting emotional pain of withdrawal.
A recent study by Florida Atlantic University found that US adolescents with cannabis use disorder have low treatment completion rates, ranging from 34.2% to 33.8%. The most common reasons for not completing treatment were dropping out, transferring facilities, and being terminated. Adolescents who began using cannabis at a younger age...
A recent study found that people in poorer areas receive three times the prescriptions for opioids than those in wealthier areas, despite a decline in overall opioid use in Canada. The research highlights the persistence of inequalities in healthcare and the need for targeted interventions to mitigate the risks of opioid misuse.
The Be Well Texas initiative, led by the University of Texas Health Science Center at San Antonio, will expand access to opioid use disorder treatment services and recovery support across rural and urban communities. This major statewide expansion aims to reduce overdose deaths and build a lasting recovery infrastructure.
Researchers at Florida Atlantic University are using a genetically tractable model organism, C. elegans, to dissect the cellular pathways impacted by amphetamines. The study aims to identify novel regulators of dopamine release and genes that mediate amphetamine's effects independently of traditional dopamine mechanisms.
A new study by Carnegie Mellon University researchers found that opioid consumption intensity varies enormously across different populations and contexts. The study suggests that tracking average intensities of use could improve our understanding of consumption patterns and inform drug policy and treatment strategies.
Researchers found that mice with weakened laterodorsal tegmentum responses exhibited reduced withdrawal symptoms and increased interactions with new objects. The interpeduncular nucleus inhibits the LDTg, suggesting a potential target for nicotine addiction treatments.
A sweeping national study by ICAMH at Hebrew University found substantial increases in substance use, behavioral addictions, and mental health disorders in Israel since the October 7, 2023 attacks. Younger, secular populations were most at risk, with sociodemographic disparities evident across repeated samples.
A recent study by Carnegie Mellon University found that illegally manufactured fentanyl primarily enters the US via counties along the Canadian border. The analysis revealed these counties accounted for over 40% of large fentanyl seizures in 2023-2024, despite comprising only 3.1% of the national population. This finding undermines eff...
A JAMA Psychiatry study recommends increasing contingency management incentives to improve opioid addiction recovery outcomes. The research team suggests using evidence-based incentive amounts, such as $128 per week for vouchers or $55 per week for prizes over 12 weeks, to effectively reduce stimulant and/or opioid use.
A new study found that providing housing and supportive services without requiring drug treatment is a surprisingly cost-effective approach to helping unhoused people with opioid use disorder. The 'housing first' model output showed that people with stable housing are more likely to enter treatment for opioid use and have a higher like...
A new online toolkit developed by the University of Ottawa and Health Canada aims to educate healthcare providers on managing opioid-related issues. The toolkit's co-creation model involves patient input, leading to a deeper understanding of chronic pain and opioid use, and a more compassionate approach to care.
The number of people seeking treatment for ketamine addiction has increased eightfold since 2014-2015, with doctors warning of serious health problems and inadequate diagnostic criteria. Doctors call for better screening tools and treatments to address the growing concern of non-prescribed ketamine use.
The UT Health San Antonio Multispecialty and Research Hospital is the first in Texas to approve use of suzetrigine, a new non-opioid medication for post-surgical pain. This medication targets the peripheral nervous system, avoiding opioid-related side effects.
Researchers will analyze course of illness, confirm ingested substances, and provide real-time data for better care. The study aims to predict effects of emerging opioids and deliver timely alerts to doctors and public health agencies.
Researchers at Flinders University found that blue-enriched light can make people less sensitive to losses, leading to riskier gambling behaviors. The study suggests that reducing blue light exposure could be a potential strategy to mitigate impulsive gambling.
A new FAU study analyzing 16 years of national data reveals the most common reasons why people with cannabis problems don't seek help, including lack of knowledge, cost, stigma, and fear of job impacts. The study also identifies consistent predictors of access to treatment, highlighting an urgent need for targeted outreach and improved...
A new study uses a fruit fly model to investigate the genetic basis of cocaine addiction. By genetically modifying bitter-sensing receptors in fruit flies, researchers found that these flies developed a preference for cocaine over sugar. This study suggests that genes involved in human cocaine addiction may also be active in fruit flies.
Researchers found that e-cigarette warnings are effective in discouraging vaping, with health harm warnings being more effective than addiction warnings. The analysis included 22,549 participants and showed no negative unintended consequences, such as encouraging people to smoke cigarettes instead of vaping.
Researchers created genetically modified fruit flies that become addicted to cocaine, revealing a potential model for understanding and treating cocaine use disorder. The study's findings suggest that the key to preventing cocaine addiction lies in the flies' ability to detect bitter flavors, which can be mimicked in humans.