A new combination of MabThera and standard chemotherapy has shown a significant increase in overall survival rate and complete remission rates in patients with aggressive non-Hodgkin's lymphoma. This treatment offers hope for improved outcomes in this increasingly common form of blood cancer.
Researchers at Fox Chase Cancer Center have discovered that the drug Oltipraz can inhibit tumor growth by blocking blood vessel formation, while also increasing protective detoxification enzymes in the body. This dual mechanism of action may make Oltipraz a promising agent for both cancer prevention and treatment.
Dr. Scott Cameron, a renowned pediatric oncologist and molecular biologist, will lead research on cell growth and cancer at UT Southwestern Medical Center. The Children's Cancer Fund provided a $525,000 grant to support his four-year research program.
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A Swedish study published in The Lancet found no association between antihypertensive drug treatments and an increased risk of cancer. The study analyzed 6600 patients with hypertension, randomly assigning them to three treatment strategies, and found no significant difference in cancer incidence between groups.
A new DNA chip method has been developed to identify and classify tumor types, offering a promising approach for cancer diagnosis and treatment. The technique uses gene expression analysis to distinguish between different types of leukemia, such as AML and ALL, and may also be used to predict clinical outcomes.
Oregon Health & Science University scientists begin human trials of a targeted drug therapy for chronic myelogenous leukemia, aiming to eliminate leukemia cells with a faulty gene. The investigational drug has shown success in destroying BCR-ABL cells in mice and animal trials.
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Cornell University researchers found that retinoic acid reverses the growth-promoting effects of oncogenes, which induce cancer. The study suggests enhanced therapies for leukemia and highlights the cancer-prevention role of carotenes in a diet rich in yellow-orange vegetables.
Researchers at Oak Ridge National Laboratory use ORNL mice to study human cancers, identifying genetic causes and potential treatments. By comparing mouse genes to human genes, scientists hope to gain a better understanding of cancer development and improve diagnosis and treatment strategies.
Researchers identify a molecular 'safety key' that normally regulates cell growth, and discovering how it can be disrupted to trigger cancer. The team found a protein called Abi-2 that fits into the normal enzyme cABL, keeping it turned off, and proposes a new way to treat cancers by targeting this molecular pathway.
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