Articles tagged with Brain Injuries
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A University of Pittsburgh study links changes in brain function to recovery in children and adolescents with concussions, using functional MRI scans. The findings confirm the importance of objective neuropsychological testing for safe return-to-play decisions.
A new MUHC study found that wearing soft protective headgear reduces the risk of concussions by 53% among adolescents aged 12-17 who played soccer. The research also suggests that most sports-related injuries are not reported, emphasizing the importance of preventive measures.
The University of Cincinnati has received a $1.7 million grant from the National Institutes of Health to research molecular treatment of brain injury. Dr. Kenneth Strauss will study eicosanoids, which can protect healthy brain cells from further damage.
Researchers found evidence of two separate networks in the brain that control voluntary behavior, such as reading a word or searching for a star. These networks work independently but toward a common purpose, and understanding their dynamics may aid in treating brain injuries.
Dr. Joseph Fins, a leading expert in medical ethics, has received the Robert Wood Johnson Investigator Award to study brain injury care and develop innovative models of treatment. The project aims to improve clinician-family communication and inform educational standards for professionals.
A recent study found that a key inflammatory regulator in the brain acts as a protector against Alzheimer's disease, helping to remove toxic clumps called plaques. The research used genetically engineered mice with pinpoint control over inflammation levels, revealing that higher IL-1beta activity actually reduced plaque buildup.
Researchers are conducting a five-year Phase III clinical trial to examine the effectiveness of induced hypothermia as a therapy for brain swelling in children with traumatic brain injuries. The study aims to enroll 340 children and assess outcomes after one year, following cooling therapy.
A study by Indiana University School of Medicine found that pediatricians and pathologists cannot agree on half the time whether a child's death from traumatic brain injury should be investigated as potential child abuse. Researchers developed a framework to help compare cases, aiming to improve uniform definitions for future studies.
Research reveals that blows to the head in amateur boxing lead to elevated levels of biochemical markers for brain injury. A particular marker for neuronal damage, neurofilament light, was found to be four times higher in boxers after a fight compared to healthy non-athletes.
A UCLA/University of Toronto team has discovered a protein called CREB controls neuron participation in memory formation, suggesting a new approach for preserving memory in people with Alzheimer's or brain injury. The study found that high levels of CREB lead to more likely storage of memories.
A recent study by Carnegie Mellon scientists found that a mouse brain can significantly compensate when limited to sensing the world through one whisker. The results provide new understanding of brain adaptability in response to sensory deprivation, which can be applied to stroke or traumatic brain injury treatment.
A UCLA study suggests that lactate may be a key fuel for the brain after traumatic injury, potentially replacing glucose. Researchers found that the brain takes up and utilizes lactate more than at any other time after injury, making it a faster and more efficient source of energy.
A study found vulnerabilities in premature infants' brains similar to those in mature brains, but also identified a significant difference that suggests different treatments are needed. Damage occurs mainly in white matter, which connects brain regions, and can lead to behavioral problems and developmental delay.
Researchers at Princeton University developed flexible electronic membranes to replicate brain injuries in the lab without damaging electrodes. The membranes enable precise measurements of cellular activity before and after traumatic brain injury, providing valuable insights into functional damage.
Researchers found that up to 36% of people with mild traumatic brain injury suffer from circadian rhythm sleep disorder, which can worsen other symptoms. The study highlights the need for improved diagnosis and treatment of sleep disorders in these patients.
Researchers found a tight correlation between the severity of spatial neglect symptoms and the degree of impairment in communication within and between two brain networks. This study suggests that testing for communication breakdowns could improve clinical assessment and treatment of stroke and other brain injuries.
Researchers discovered that APOE genotypes increase susceptibility to cerebral palsy in newborns. The study found a threefold-elevated risk for children with quadriplegia/triplegia and more severe motor impairment.
Patients with low to moderate blood alcohol levels may have a reduced risk of dying after arriving at the hospital with a traumatic brain injury. In contrast, those with high blood alcohol levels are more likely to die in the hospital, highlighting a potential neuroprotective effect of alcohol.
A study found that only 14 of 15 hospitals provided inadequate discharge information, with most instruction sheets written at a high reading level. The researchers propose an evidence-based emergency department discharge form to improve patient safety and reduce the risk of brain hemorrhage or swelling.
A new study found that traumatic brain injury reduces potassium-chloride co-transporter 2 (KCC2) levels in the dentate gyrus, leading to abnormal activity and seizures. The research also suggests that this imbalance may impair memory formation, particularly antegrade memory.
A study at Emory University Health Sciences Center found that giving progesterone to trauma victims shortly after a brain injury may reduce the risk of death and disability. The researchers also found a 50% reduction in death rate and significant improvement in functional outcome among patients who received progesterone.
Researchers found that severely impaired patients taking rivastigmine showed significant improvement in attention and verbal memory test scores compared to placebo-treated patients. Rivastigmine was also found to be safe and well-tolerated with common side effects including nausea and dizziness.
Scientists have identified special proteins that help repair and protect the brain after it has been damaged by a lack of oxygen. Dr Nicole Jones and her team found that these proteins increase during oxygen deprivation, regulating processes like red blood cell production and glucose flow to the brain.
Researchers found that chronic ibuprofen therapy given after brain injury worsened cognitive abilities in animal models. The study suggests potential implications for traumatic brain injury patients who often receive ibuprofen for chronic pain.
Researchers like Joseph Messina and Patrick Kochanek explore ways to improve survival rates for patients with trauma injuries using insulin-sensitizing agents and novel resuscitation fluids.
Researchers found that cooling a person by 2°C during the first day after resuscitation can significantly improve their chances of recovering from cardiac arrest. The study, which used rats to replicate human brain injury, showed that even modest cooling of the brain can have beneficial effects on recovery.
A new study is recruiting over 3,500 rugby union players aged 16-35 to gather data on head injuries and recovery. The research will inform the development of evidence-based guidelines to manage player return to sport after concussion.
Researchers tracked individuals infected with EBV, RRV, or Q fever and found post-infective fatigue syndrome lasting six months or longer. The study suggests that brain damage during acute infection phase may be responsible for chronic fatigue symptoms.
Rochester researchers emphasize the need for more accurate and rapid diagnostic tests for concussions to improve treatment outcomes and prevent long-term neurological damage. Current CT scans are often biased, leading to underdiagnosis of significant axonal injuries.
A study by Steinar Sulheim and colleagues found that helmet use is associated with a 60% reduced risk of head injury among skiers and snowboarders. The risk for head injury was also found to be higher among snowboarders than alpine skiers, highlighting the importance of helmet use in preventing these injuries.
Research by Lingraphicare America reveals that speech generating devices can help stroke patients recover from aphasia, even years after the initial injury. The study found nearly half of subjects improved to a less severe diagnostic category, with gains observed across all severity levels.
Pittsburgh researchers found biomarkers in infant blood that can identify possible cases of shaken baby syndrome, a traumatic brain injury often misdiagnosed. The study's findings have significant implications for decreasing morbidity and mortality in infants with SBS.
A recent study compared neurocognitive recovery in NFL and high school athletes after concussion. The results showed that NFL players returned to pre-injury baseline performance in just one week, while high school athletes took longer to recover. The study used computerized neurocognitive testing tool ImPACT to evaluate the athletes.
A new study published in the Journal of Athletic Training found that traditional neck muscle resistance training does not reduce a player's head acceleration during impact, contrary to popular thinking in athletics. The eight-week program did improve neck muscle strength but failed to enhance head stabilization.
A large-scale observational study found that athletes wearing the Riddell Revolution helmet were 31% less likely to sustain a concussion compared to those wearing traditional helmets. However, proper injury management and recovery time remained unchanged between the two groups.
A Phase I clinical trial is underway to test the safety and potential of using child's own bone marrow stem cells to treat traumatic brain injury. The study aims to establish the safety of the procedure and observe possible therapeutic effects.
Researchers at Washington University in St. Louis have developed a new technique to image brain deformation after impact, using magnetic resonance imaging (MRI). The study shows that the brain tries to pull away from attachments, leading to significant deformation of the front of the brain.
A study of 18 children who suffered injuries from private-use go-carts found that head injuries were the most common, with 22% of cases requiring surgery. The primary cause of these injuries was loss of control leading to collisions or ejection, highlighting the need for adult supervision and safety equipment.
A recent study found go-cart injuries among children to be severe and often preventable, highlighting the importance of adult supervision and strict safety regulations. The researchers analyzed medical records from 160 hospitalized children aged 16 and under, resulting in 18 confirmed go-cart injuries with average age 10.3 years.
A recent study has found that patients with head injuries are ten times more likely to die than those with other types of injuries. The lack of neurosurgical care is associated with a significant increase in mortality rates, highlighting the need for improved emergency response systems.
Scientists have found a biomarker, a protein called NF-H, that signals the presence of disease or injury in the blood and spinal fluid. The discovery could lead to a simple handheld device for diagnosing brain or spinal injuries with just a few drops of blood.
Researchers found that brain regions beyond the injury site play a critical role in understanding behavioral deficits and assessing options for acceleration of recovery from stroke-related spatial neglect. Functional magnetic resonance imaging scans revealed activity changes in distant brain areas correlated with impairment severity.
Researchers found that hypothermia significantly reduced brain injury and death from oxygen loss in newborns. The study, led by Seetha Shankaran, M.D., at Wayne State University, showed a 44% lower rate of moderate to severe disability or death in infants treated with cooling compared to those in the control group.
A new study at UNC reveals that retired professional football players have a 37% higher risk of Alzheimer's disease due to concussions. The study found that history of recurrent concussions and sub-concussive contacts may be risk factors for late-life memory impairment, mild cognitive impairment, and early expression of Alzheimer's dis...
Researchers found that language activity in the brain becomes more evenly distributed between both hemispheres with age, allowing for potential rehabilitation. This shift may explain why young children who have had a portion of their brain removed can recover completely.
Researchers found that adult stem cell therapy significantly improves recovery of motor function and balance in an animal model of cerebral palsy. The treatment, which involves injecting stem cells directly into the brain, showed a 20% reduction in favoring the unaffected side and a 25% improvement in balance.
A new study by UCLA researchers reveals that heart-failure patients suffer from both physical and mental injuries, with brain damage impacting their ability to exercise. The findings emphasize the need for cardiologists to recognize this connection and develop therapies to prevent brain injury and boost brain function.
A study found that doctors and caregivers often focus on physical and cognitive effects, but patients report additional challenges such as social isolation and self-consciousness. The research highlights areas that deserve more attention and suggests interventions like lip reading training and videos to improve patient recovery.
Researchers found that pomegranate juice reduced brain tissue loss by 60% in mice whose mothers drank water mixed with pomegranate concentrate. The study suggests that pomegranate juice may provide neuroprotective effects and potentially reduce the impacts of hypoxic ischemic brain injury.
A University of Pittsburgh study published in the Journal of Neurosurgery found that athletes with post-traumatic migraine (PTM) after a concussion experienced increased neurocognitive function impairment. This suggests that clinicians should exercise caution when managing concussed athletes with PTM.
The CRASH trial found that corticosteroids increased the risk of death at two weeks compared to a placebo. The study also showed higher risks of death or severe disability in the corticosteroid group than in the placebo group. Corticosteroids are widely used to treat head injuries, but this practice may be harmful.
Researchers have found that an experimental drug can effectively prevent much of the brain damage caused by traumatic injury. In a study using rat models, the drug was shown to reduce brain damage and improve cognitive and motor function. The breakthrough could potentially lead to new treatments for human traumatic brain injuries.
The OHSU study found that ThinkFirst significantly improves knowledge of injury prevention among program participants, leading to a decline in traffic-related fatalities and injuries. The program has educated over 250,000 children on injury prevention since its inception in Oregon.
Ivan Soltesz, a UCI neurobiologist, received the Senator Jacob Javits Award in the Neurosciences to investigate post-traumatic epilepsy research. The $2.7 million grant aims to develop new anti-epileptic treatment strategies for people who have recovered from severe head trauma.
A review of 71 studies found that well-motivated, younger patients with no loss of consciousness are less likely to suffer from postconcussional syndrome. The majority of patients recover completely within three to six months, but some predictors include female gender and being involved in a lawsuit.
Researchers found that induced moderate hypothermia (32–33°C) is a safe therapeutic intervention for children with severe traumatic brain injury, reducing mortality and intracranial hypertension. The treatment protocol also showed potential to improve functional outcomes in young patients.
Researchers found that football players suffered significantly more neck injuries than those playing hockey or soccer. The study attributed this increase to the design of football tackles, which impede opposing player motion.
Researchers identify basal forebrain cholinergic system as essential substrate for cortical plasticity and functional recovery after focal cortical injury. The study found that rats lacking a cholinergic system recovered only about 18% of their reaching ability after rehabilitation training.
A study published in the Journal of Neurosurgery found that golf-related head injuries in children increased by 15% between 1996 and 2002. The majority of these injuries occurred outside golf courses, highlighting the need for cautionary guidelines and safety training programs to prevent accidents.
A Penn State-led education program has significantly reduced incidents of shaken baby syndrome in western New York, resulting in a 47% decrease in cases. The program, which costs less than $10 per infant, provides critical information to parents at the time of birth and is designed to be implemented with minimal time and resources.