A new study published in Mayo Clinic Proceedings suggests that consuming more than 28 cups of coffee per week may increase mortality risk in individuals under 55 years old. The study of over 40,000 participants found a statistically significant association between heavy coffee consumption and all-cause mortality.
The University of Louisville Diabetes & Obesity Center has won a second $11.25 million COBRE grant to continue its research on diabetes and obesity. The center aims to develop new prevention methods and treatments for these conditions, which are major health threats in the US.
A systematic review of six studies involving over 900,000 patients found a positive association between severe hypoglycaemia and cardiovascular disease risk. The link was consistent across all studies, suggesting that avoiding severe hypoglycaemia may be crucial to preventing CVD in type 2 diabetics.
Researchers at Malmo University found that saliva samples can reveal traces of serious illnesses, such as cancer and diabetes. This breakthrough could lead to earlier diagnosis and treatment with a simple saliva test.
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Researchers developed an ischemic stroke model using sodium alginate microspheres in miniature pigs. The method successfully blocked the skull base retia, establishing a reliable model for studying pathogenesis and developing safe drugs for cerebral infarction.
Researchers found that excessive PKC beta in endothelial cells exacerbates atherosclerosis, a condition where blood vessel walls thicken due to fatty deposits. This inhibition leads to decreased nitric oxide production, increasing cardiovascular disease risk.
A new study suggests that implementing smoke-free laws and increasing tobacco taxes in India can reduce cardiovascular disease deaths, potentially preventing 9 million deaths by 2022. The findings are based on a mathematical model that considered unique populations with different risk factors.
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A large study using a new genetic method found that overweight is associated with an increased risk of heart failure. The study, which included nearly 200,000 subjects, also confirmed that obesity leads to higher insulin values and increased inflammation markers.
A large-scale genetic study found a significant link between high vitamin D levels and reduced blood pressure, reducing the risk of hypertension. The researchers used genetic variants as proxy markers for vitamin D status to test for causality, providing strong evidence for the potential prevention of cardiovascular disease through vit...
Researchers at Lund University discovered a substance that prevents atherosclerosis caused by high blood sugar levels. The substance only affects NFAT-activated cells and has no impact on the immune system. This breakthrough offers hope for a targeted treatment to address vascular damage in diabetes patients.
A new study from Wake Forest Baptist Medical Center suggests that cardiovascular disease (CVD) plays a role in cognitive decline before it is clinically apparent in patients with type 2 diabetes. The research found that CVD risk factors, such as calcified plaque and vascular status, contribute to type 2 diabetes-related cognitive decline.
A new study published in the Journal of the American College of Cardiology found that hysterectomy with or without ovary removal does not increase a woman's risk of cardiovascular disease compared to natural menopause. Middle-aged women who have had hysterectomy can be encouraged due to reduced cardiovascular risk factors.
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Researchers at the Montreal Heart Institute have discovered a blood protein that contributes to the early development of atherosclerosis. Angiopoietin-like protein 2 (angptl2) is found six times higher in subjects with coronary heart disease than healthy individuals, making it a potential early biomarker for the condition.
New research from Johns Hopkins finds that high doses of vitamin D supplements do not confer additional benefits on cardiovascular health or longevity in healthy adults. However, elderly individuals, postmenopausal women, and those with kidney disease may still benefit from higher blood levels of the sunshine vitamin.
Individuals who experience an upper gastrointestinal bleed may be more likely to die from other causes, particularly malignant tumours and cardiovascular disease. A study published in PLOS Medicine found that the risk of death due to non-gastrointestinal causes was higher for those with an upper GI bleed.
Regular binge drinking in college causes immediate changes in circulation, increasing the risk of developing cardiovascular disease. College students who binge drink may experience impaired vascular function similar to those with daily heavy alcohol consumption.
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Scientists found that inhibiting epoxide hydrolase with tAUCB and activating PPARγ with rosiglitazone had synergistic effects on cardiometabolic syndrome, reducing cardiovascular risk factors and kidney disease progression.
A Swedish study published in Neurology suggests a decline in the risk of developing dementia over the past 20 years. The study, which analyzed data from the SNAC-K study on aging and health, found that improvements in cardiovascular disease prevention may have contributed to this decrease.
A large population study from Denmark found that individuals deemed mentally vulnerable are at a significantly increased risk of both fatal and non-fatal cardiovascular disease. The study's results showed that mental vulnerability was associated with a 36% higher risk of events, independently of classical risk factors.
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A recent study found that long-term cortisol exposure in seniors is associated with an increased risk of heart disease and stroke. The study used scalp hair analysis to measure cortisol levels over a three-month period, revealing a clear link between chronically elevated cortisol levels and cardiovascular disease.
A study found low prevalence of healthy lifestyle behaviors, such as regular physical activity and healthy diets, in individuals with CHD or stroke globally. The data suggests that high-income countries have higher rates of cessation from smoking and healthier lifestyles.
A large study found that high serum C-peptide levels are linked to an increased risk of death from all causes and cardiovascular disease. People with high C-peptide levels had a 1.8- to 3.2-fold increased risk compared to those with low levels.
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A study published in the BMJ found that a 5kg population-wide weight loss resulted in a significant reduction in Type 2 diabetes and cardiovascular disease mortality. The Cuban experience of rapid weight loss during economic crisis demonstrates the potential health benefits of reversing the global obesity epidemic.
A study published at the American Heart Association's meeting found that consuming excessive sodium led to an estimated 2.3 million heart-related deaths globally in 2010. This represents a significant burden on public health, with 40% of these deaths occurring among men and 60% among women.
A new study in Canada has found that over 40% of healthy individuals are taking daily aspirin to prevent cardiovascular disease, despite recent literature suggesting its limited benefits. The study's authors hope to raise awareness among physicians and patients about the importance of discussing anti-platelet medication use.
A study found that elevated PAPP-A levels were associated with a higher risk of cardiovascular events in people with cardiac chest pain due to heart disease. The presence of PAPP-A also predicted cardiovascular events, including heart attacks and strokes, even after controlling for other factors.
A recent study published in JAMA found that quitting smoking is associated with a lower risk of cardiovascular disease, even after subsequent weight gain. The study included data from the Framingham Offspring Study and found that among participants without diabetes, recent quitters had a 53% lower risk for CVD compared to smokers.
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The risk of cardiovascular sudden death in young competitive athletes is extremely low, occurring only about 30% of the time and in a small percentage of those due to diseases detectable by ECGs. Current screening initiatives have potential impact on 10-15 million young adults but do not provide evidence for necessity of ECGs
A recent study found that Chinese women who started menstruating later or went through menopause at an older age were less likely to develop cardiovascular disease. The study also discovered a higher risk of osteoporosis for those with early menopause, with benefits seen in women over 50 when entering menopause.
Scientists identify genes involved in cholesterol metabolism and cardiovascular disease risk by selectively decreasing gene expression using RNA interference. The study provides a new approach for understanding the mechanisms of cardiovascular disease and improving its prediction and diagnosis.
Researchers found that blockages in coronary arteries, as measured by non-invasive CT scans, were significantly higher in patients who experienced a stroke. CAC levels above 400 Hounsfield units increased the risk of stroke three times in those under 65 and at low cardiovascular risk.
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A psychiatrist proposes a new subspecialty to address the link between depression and heart disease. Interleukin-6 levels were found to be higher in depressed patients than healthy controls.
Researchers at the University of Gothenburg have made significant findings on the link between gut bacteria and cholesterol metabolism. The study reveals that gut bacteria can reduce bile acid synthesis in the liver by signaling through a specific protein, which could lead to new treatments for cardiovascular disease.
A study of 61,443 Swedish women found that high calcium intake doubles the risk of cardiovascular death, particularly among those who take supplements. The researchers suggest that diets extremely low or high in calcium can disrupt normal blood levels of calcium.
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Researchers found that cured Cushing's disease patients who had depression when symptoms started were at elevated risk of mortality and cardiovascular disease. Men were more susceptible than women due to a lack of follow-up care, while patients with diabetes were also at higher risk of developing cardiovascular disease.
The Gulf region is expected to experience a massive wave of cardiovascular disease in the next 10-15 years, driven by high obesity rates and diabetes prevalence. Prevention services are lacking, but experts call for a public health strategy to promote physical activity and healthy diets.
A study of 1,265 pregnant and reproductive women found that obstructive sleep apnea is associated with a 31% incidence of cardiac dysfunction. The research suggests that echocardiograms should be considered in the clinical management of women with OSA and cardiac symptoms.
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Researchers analyzed blood plasma samples from mice to identify protein traits associated with genetic markers, paving the way for diagnostic and therapeutic targets
Researchers have found a gene associated with an unusual type of cholesterol that increases the risk of developing aortic stenosis, the most common form of heart valve disease. High levels of Lipoprotein (a) cholesterol are predicted primarily by an individual's genetic make-up.
A large study of over 388,000 participants found that high supplemental calcium intake was associated with an increased risk of cardiovascular disease death in men, while dietary calcium intake had no such effect. The study suggests that sex may play a role in the cardiovascular effects of calcium supplements.
A new study published in the American Journal of Human Genetics finds a significant link between schizophrenia and cardiovascular disease. The researchers used a novel statistical model to identify 16 new loci associated with both conditions, including triglyceride levels and waist-hip ratio.
A large study found that erectile dysfunction severity corresponds to increased risk of cardiovascular disease hospitalization and all-cause mortality in men. The study analyzed data from over 95,000 men and found significant associations between ED severity and CVD risk, even among those without known CVD.
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A major new study has found that men with erectile dysfunction are at higher risk of hospital admission for heart disease and premature death. The research, which examined data from over 95,000 men, also showed a direct link between the severity of erection problems and the risk of cardiovascular events.
International experts emphasize the need for more research on non-communicable diseases like cardiovascular disease and diabetes in low- and middle-income countries. Current research is limited, but collaboration between high-income and low-middle-income countries can provide valuable insights.
Researchers found individuals with schizophrenia have shorter life expectancy due to increased risk of cardiovascular disease and cancer. Women with schizophrenia were particularly vulnerable, facing a threefold higher risk of cardiovascular disease and a 1.7 times greater chance of cancer-related death.
An autopsy-based study among US service members (2001-2011) reveals high prevalence of atherosclerosis, associated with older age, lower education level, and higher BMI. The study's findings highlight the need for continued efforts to reduce cardiovascular risk factors.
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A new study found that heart calcium scans can identify people with Type 2 diabetes at high risk for developing potentially fatal cardiovascular disease, as well as those at low risk. The test can help doctors provide more effective treatments and improve outcomes by diagnosing a precise risk level.
Researchers found a link between a specific gene variant and lower triglyceride levels, as well as higher HDL cholesterol. Carriers of the variant tend to have lower risk of cardiovascular disease, particularly when consuming more polyunsaturated fat.
Researchers have found that bilirubin can limit arterial lesions by blocking vascular smooth muscle cell growth, potentially preventing heart attacks and other cardiovascular symptoms.
Researchers at VCU Massey Cancer Center have identified a potential mechanism for reducing obesity by targeting the production of enzyme Tyk2. The study found that Tyk2 helps regulate brown adipose tissue (BAT), which is responsible for energy expenditure and maintenance of body temperature. By manipulating Tyk2 levels, scientists were...
Research shows that obstructive sleep apnea causes early cardiovascular damage similar to diabetes, highlighting the importance of seeking medical attention. Patients with moderate to severe OSA have endothelial dysfunction and higher arterial stiffness, which can lead to heart failure.
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A recent study published in BMJ Open found that low-income individuals have poorer adherence to the Mediterranean diet, leading to higher rates of obesity. The researchers analyzed data from 13,000 participants and discovered a significant association between income levels and dietary habits.
A new study published in the American Heart Association journal Circulation found that a healthy diet rich in vegetables, fruits, grains, and fish can reduce the risk of recurrent heart attacks and strokes by up to 35%.
A five-year study of almost 32,000 patients found that a heart-healthy diet significantly reduces the chance of a second heart attack and stroke in people with cardiovascular disease. The study showed that dietary modification offers consistent benefits beyond drug therapy alone, saving lives globally.
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A new screening tool has been developed to help identify individual vulnerability to health and safety impacts of shift work. The tool, for a condition known as shift work disorder, aims to reduce workplace accidents and illnesses caused by shift work, including cardiovascular disease and cancer.
Recent analysis by Oregon State University scientists suggests that both fish consumption and omega-3 supplements can prevent heart disease. The review highlights the importance of DHA and EPA in human health, and notes that plant-derived sources have less benefit than cold-water fish.
A study of 292 Brazilian women aged 45-72 found that daily step count is a strong predictor of health outcomes, with active women less likely to be obese or develop metabolic syndrome. The study supports the importance of incorporating physical activity into daily life for midlife women's overall health.
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A new study suggests that increasing Hsp70 expression may help reduce excessive reactive oxygen species production, a key contributor to cardiovascular disease. Researchers found that Hsp90 inhibitors can increase Hsp70 levels, leading to decreased oxidative stress and improved blood vessel function.
An expert panel confirms that calcium supplements are a valuable tool for maintaining bone health, with no increased risk of cardiovascular disease. The panel reviewed the scientific literature and concluded that adequate calcium intake is crucial for strong bones across all age groups.
A study published in the European Heart Journal found that relatives of young people who died suddenly from a heart-related problem are at greatly increased risk of developing cardiovascular disease. The study suggests that close relatives of these victims should be screened to detect those who would benefit from preventive treatment.