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Whole grain diets lower risk of chronic disease

A study by Penn State researchers found that consuming whole grains can lead to significant weight loss and reduced risk of chronic diseases. The study showed that the whole grain group experienced a lower body weight, lower blood pressure, and increased intake of fiber and magnesium compared to the refined grain group.

SourcePenn State·JournalAmerican Journal of Clinical Nutrition·DateFeb 5, 2008

The HLA-DRB1 gene and premature death in rheumatoid arthritis

Researchers identified the HLA-DRB1 gene as a predictor of premature death from cardiovascular disease in inflammatory arthritis patients. The study found that having two copies of the shared epitope allele increased the risk of death from all causes and cardiovascular disease, particularly among current smokers.

SourceWiley·JournalArthritis & Rheumatism·DateJan 31, 2008

Sedentary lifestyles associated with accelerated aging process

A recent study published in the Archives of Internal Medicine found that individuals with sedentary lifestyles exhibit shorter telomeres, indicating an accelerated aging process. Regular exercise, however, has been shown to reduce oxidative stress and inflammation, which may help mitigate this effect.

SourceJAMA Network·JournalArchives of Internal Medicine·DateJan 28, 2008

Pioglitazone lowers cardiovascular risk in diabetic patients with kidney disease

Chronic kidney disease significantly increases the risk of cardiovascular events in diabetic patients. Pioglitazone has been shown to lower this risk, particularly among those with moderate to severe renal disease. The study found that pioglitazone reduced all-cause death, myocardial infarction, and stroke by one-third.

SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateDec 12, 2007

A call to action to prevent chronic diseases

Achieving a 2% annual reduction in mortality rates due to chronic diseases could prevent 36 million deaths by 2015. The authors urge key players, including governments, industries, and NGOs, to prioritize policies and programs to tackle chronic diseases, such as tobacco control, diet modification, and physical activity promotion.

SourceThe Lancet_DELETED·JournalThe Lancet·DateDec 4, 2007

Is your heart aging faster than you are?

A new MUHC study found that informing patients about their cardiovascular risk and receiving ongoing feedback from their doctor leads to greater drops in lipid levels. Patients with higher risk profiles experienced a greater impact on their risk profile, highlighting the importance of communicating calculated cardiovascular risk.

SourceMcGill University Health Centre·JournalArchives of Internal Medicine·DateNov 26, 2007

UMass Medical School study identifies the best weight-loss plans for heart health

A new study by UMass Medical School researchers found that certain popular weight-loss plans significantly outperform others in reducing cardiovascular disease risk. The Ornish, Weight Watchers High Carbohydrate, and New Glucose Revolution plans scored highest due to their emphasis on whole grains, fruits, and vegetables.

SourceUMass Chan Medical School·JournalJournal of the American Dietetic Association·DateOct 1, 2007

Eating competence may lower risk of heart disease

A study by Penn State found that individuals with higher eating competence have a lower risk of cardiovascular disease. The research suggests that training people in becoming eating competent may be an effective way to encourage healthy eating behaviors.

SourcePenn State·JournalJournal of Nutrition Education and Behavior·DateSep 18, 2007

Secondhand smoke increases risk of dementia

Research suggests that elderly people exposed to secondhand smoke are at a higher risk of developing dementia. The study found that those with high lifetime exposure were approximately 30% more likely to develop dementia than those with no exposure. High exposure was defined as more than 30 years of exposure to secondhand smoke.

Pistachios lower cholesterol, provide antioxidants

Researchers found that pistachio amounts of 1.5 ounces reduced LDL cholesterol levels by 11.6% and total cholesterol by 8.4%, while the higher dose showed significant reductions in lipoprotein ratios. Pistachios also increased antioxidants in the blood, which may help reduce inflammation.

High insulin levels impair intestinal metabolic function

Researchers at the University of Alberta found a connection between high insulin levels and impaired intestinal lipid metabolism in an animal model, supporting the role of intestinal metabolic dysfunction in cardiovascular disease. Excessive insulin slows chylomicron removal from the bloodstream, leading to blockages and heart problems.

SourceUniversity of Alberta·JournalAtherosclerosis·DateApr 24, 2007

Women and heart disease

A comprehensive review highlights clinically relevant differences in women and men's heart disease prevalence, presentation, management, and outcomes. Young women with acute coronary syndrome face higher mortality rates than young men.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateMar 12, 2007

Garlic does not appear to lower cholesterol levels

A six-month study found that three forms of garlic, including raw and commercial supplements, did not significantly reduce low-density lipoprotein (LDL) cholesterol in adults. The results suggest that garlic may have other beneficial health effects, but its ability to lower LDL cholesterol is uncertain.

SourceJAMA Network·JournalArchives of Internal Medicine·DateFeb 26, 2007

Reduction of body iron stores and cardiovascular outcomes

A recent study published in JAMA found that reducing body iron stores through phlebotomy in patients with peripheral artery disease did not significantly decrease the risk of death or nonfatal cardiovascular events. However, younger patients and those without diabetes showed apparent improvement with iron reduction.

SourceJAMA Network·JournalJAMA·DateFeb 13, 2007

Update on Tufts vitamin K research

Researchers at Tufts University have found that while older adults consume more vitamin K than younger adults, many still do not meet the recommended intake. High phylloquinone intake may be associated with better dietary habits and reduced risk of cardiovascular disease, but further research is needed.

SourceTufts University·JournalCurrent Opinion in Clinical Nutrition & Metabolic Care·DateFeb 9, 2007

Existing research supports metabolic syndrome link to cardiovascular disease

A recent meta-analysis supports the existence of metabolic syndrome as a predictor of cardiovascular disease and death, particularly in women. The study analyzed over 37 studies and found that the constellation of conditions constituting metabolic syndrome increases heart risk compared to individual factors alone.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateJan 22, 2007