Articles tagged with Cardiovascular Disorders
Researchers are working on a four-year project to develop a personalized model that uses detailed blood flow information to detect obstructions in the aorta. The project aims to improve prenatal testing so that doctors can spot problems in the aorta before a baby is born and recommend treatments.
The first-ever EU Screening Week aims to detect risk factors earlier and prevent serious cardiometabolic diseases. Key health indicators like blood pressure, blood sugar, and cholesterol will be checked to take preventive action sooner.
Researchers at Sanford Burnham Prebys discovered that blocking an energy transfer enzyme shifts mammalian hearts into a regenerative state, promoting regeneration and improving recovery after a heart attack. By modulating heart cell metabolism, scientists can potentially awaken the heart's dormant regenerative abilities.
Researchers found a 44% lower risk of death from any cause after one year and 35% lower risk after two years among type 2 diabetes patients starting continuous glucose monitoring. CGM use also showed a reduced risk of cardiovascular events, including heart attack and stroke.
A new study found that drones can significantly reduce the time between cardiac arrest reporting and defibrillation, particularly in rural and congested areas. By combining fixed AEDs with drones, access times can be reduced by up to 3.76 minutes, with over 95% of cases covered within five minutes.
Researchers identified a common signaling pathway activated by three adenosine receptor subtypes, leading to cardiac fibroblast activation and scarring. Blocking these receptors together produced a stronger antifibrotic effect, suggesting a potential therapeutic target for heart disease.
A new blood test and scoring system could reduce hospital visits for patients with chest pain by up to 34% by triaging them at home or to their general practitioner. The study found that 165 patients out of 483 assessed by ambulance crews using the test and scoring system were left at home, compared to 19 out of 539 without the test.
A new study suggests that semaglutide reduces heart disease risk beyond just weight loss, but the exact mechanism is unclear. The study analyzed data from a clinical trial of semaglutide, which found that patients taking the drug had a 20% lower risk of heart disease, but only half of this reduction could be explained by changes in kno...
A new study aims to find new ways to prevent strokes in people with chronic migraine by understanding the link between cardiovascular and cerebrovascular health. The research also explores the role of immune cells in blood vessels and their impact on migraine attacks.
A study found that adolescents with a high body mass index may age biologically faster, increasing their risk of developing obesity-related diseases and premature death. The study's findings suggest a link between genetic predisposition to high BMI and accelerated biological aging.
Exercise-based cardiac rehabilitation reduces hospital admissions by a third and heart attack risk by more than a quarter, with long-term benefits and cost-effectiveness. Digital programmes can be just as effective as traditional centre-based services, making rehabilitation more accessible.
New models predict enhancer-gene interactions from single-cell data, enabling accurate mapping across cell types. The models use CRISPR experiments to train, performing well on datasets of varying sizes and sequencing depths. This breakthrough charts enhancer-gene regulation across thousands of cell types.
A new study has found a significant link between Long COVID and POTS, with nearly two-thirds of Long COVID participants meeting the diagnostic criteria for POTS. The study suggests that POTS may be contributing to symptoms such as dizziness, fatigue, and brain fog in some individuals with Long COVID.
A nationwide study found that lower temperatures are a significant risk factor for cardiac arrests, with a daily temperature drop of over 5°C serving as a warning signal. The study developed a predictive model using meteorological data to estimate expected daily numbers of cardiac arrests up to 3 days in advance.
A systematic review and meta-analysis of 87 clinical trials found that consuming four to six servings of wholegrain per day can lower cardiovascular risk factors, including body weight, waist circumference, and total cholesterol levels. Benefits were most pronounced at intakes of 60 to 100 grams per day.
A new study by Michigan Medicine found that heart surgery infection rates vary significantly across U.S. hospitals, with some experiencing nearly double the risk of others. By reducing infections, hospitals could prevent 2,600 infections and reduce Medicare spending by $441 million annually.
Researchers found structural changes in the retina in people with atrial fibrillation, detectable up to four years before diagnosis. The study suggests retinal imaging could identify those at risk of atrial fibrillation before it causes harm.
Researchers identified six protein signatures in children as young as 8 that significantly influence the risk of developing cardiovascular-kidney-metabolic disease in adulthood. These protein signatures were also present in adults at high risk of irreversible cardiovascular-kidney-metabolic disease. The study suggests that early interv...
Research of over 11,000 people found that high nighttime light exposure is associated with thickening of the heart's left ventricle and reduced flexibility during heartbeats. The study suggests that reducing nighttime light exposure could be a strategy for preventing heart disease.
Even low levels of nighttime light exposure can lead to structural changes in the heart, increasing the risk of cardiovascular disease. Researchers analyzed data from 11,017 participants and found that those exposed to higher levels of light saw a thickening of the heart's walls and reduced flexibility during a heartbeat.
Research found that after three hours of exposure to pollution, heart rate variability declines, indicating increasing physiological stress on the heart. The study suggests that individuals with cardiovascular conditions or those spending long periods outdoors should take note of air quality alerts.
A US study of 20 years of health data found that hormone therapy initiated during peri- or early postmenopause reduces cardiovascular disease risk by 22% compared to those who did not use hormone therapy. The protective effect was strongest among Black women and those who initiated therapy within 10 years of menopause onset.
A new ERC-funded project at Aarhus University aims to investigate how hormones, stress, and genetic factors influence women's coronary arteries. The project will develop new models to explain why certain cardiovascular diseases affect women differently from men, and may lead to personalized rupture-risk maps and improved diagnosis and ...
A new study found that inducing mitochondrial reactive oxygen species (ROS) during embryonic development protects the adult heart from chemotherapy toxicity in mice. The study discovered that stressed mitochondria release citrate, leading to long-term epigenetic changes that promote beneficial mitohormetic adaptations. These findings s...
The American College of Cardiology and American Heart Association have introduced a new framework, Tactical Clinical Management (TCM), to evaluate cardiovascular risk and fitness for duty in tactical athletes. This guidance addresses the unique needs of professionals working in high-risk environments, where sudden incapacitation can af...
A new study suggests that eating jetlag, which disrupts the body's biological rhythm, may increase the risk of cardiovascular disease in men. The study found that each additional hour of eating jetlag was associated with a 14% increased risk of cardiovascular disease and a 21% increased risk of coronary heart disease.
Researchers found that meal timing programs the liver's daily rhythms and can have serious metabolic and health consequences when out of sync. The liver uses food signals to activate metabolic pathways, which can conflict with the body's natural circadian clock, leading to health issues.
A new study from the University of Colorado Boulder reveals how the brain's defense mechanism can backfire, forming micro-clots that damage tissue after the original clot is gone. This phenomenon, known as no reflow, affects up to 50% of stroke patients and can lead to long-term disability or death.
The congress featured over 1,750 sessions and 12 Hot Line sessions highlighting practice-changing findings in cardiovascular science. ESC Congress 2026 also released three clinical practice guidelines and the Fifth Universal Definition of Myocardial Infarction.
Research suggests that mental health conditions, including PTSD, substance abuse, and depression, can increase the risk of future cardiovascular risks such as heart attacks, strokes, and cardiovascular death. Alcohol abuse was found to be the top psychiatric predictor of serious heart and brain conditions for both men and women.
A new study found that men with nonmetastatic prostate cancer who replaced saturated and animal fats with unsaturated and plant-based fats had a lower risk of death. Replacing about 10% of daily calories from animal fat with plant-based fat was associated with a 16% lower rate of death.
Researchers have developed a human engineered heart tissue model of diastolic heart failure, enabling treatment testing with SGLT2 inhibitors, which partially prevented disease development. The model demonstrated anti-inflammatory effects of SGLT2i, improving ion exchanger function and preventing accumulation of ions in tissues.
A short mitochondrial protein, STMP1, helps maintain the heart's energy-producing structures and protects against inflammation and failure. Researchers found that restoring STMP1 or blocking inflammation can significantly protect heart function.
C.S. Mott Children's Hospital is the first hospital in the US to implant an expandable heart valve, the Autus Valve, during the FDA review phase. The device is designed to grow with children and can potentially reduce the need for replacement surgeries.
A clinical trial has demonstrated a new treatment that reduces bleeding within the heart muscle and preserves heart function in severe heart attack patients. The trial tested a peri-reperfusion therapy that limits hemorrhagic myocardial injury after primary percutaneous coronary intervention.
A phase 2 clinical trial found that a monoclonal antibody targeting interleukin-6 achieved sustained reductions in inflammation biomarkers for six months in patients with chronic kidney disease. The therapy, known as pacibekitug, was well-tolerated and showed favorable effects on additional biomarkers associated with cardiovascular risk.
A new trial has found that implanting an ICD in patients with mild-to-moderate heart dysfunction can reduce sudden cardiac death, particularly in younger patients. This breakthrough has the potential to save lives and expand treatment options for patients who previously were not eligible for ICDs.
Dr. Sebastian Spethmann joins JMIR Cardio as Editor-in-Chief, bringing expertise in heart failure, cardiomyopathies, and digital health. He aims to integrate digital advancements into routine clinical care, enhancing cardiovascular health systems and patient outcomes.
Researchers discovered that SGLT2 inhibitors activate PANK1, a key enzyme that boosts energy production and improves heart function in heart failure patients. Increasing CoA production improved the ability of human heart cells to contract and relax, two critical functions impaired in heart failure.
A study led by Albert Einstein College of Medicine found that children of centenarians live longer and have lower risks of cardiovascular disease and hypertension. The research, analyzing data from three geographically diverse studies, suggests that inherited biological factors beyond lifestyle contribute to exceptional healthy aging.
The Cardiovascular Research Foundation (CRF) presents 28 studies at TCT 2026, highlighting advances in minimally invasive interventions, pharmaceutical therapies, and breakthrough technologies. Key findings include improved outcomes for patients with heart and vascular disease.
A new AI-based diagnosis tool can detect hypertension and diabetes from a single facial video, with high accuracy and potentially reaching far more people than traditional screening methods. The algorithm can estimate blood pressure from a facial video alone, without a cuff.
Researchers developed a risk calculator that estimates short-term risk of diabetes complications using routine health data. The tool analyzes insurance claims and electronic health record data to provide monthly, encounter-level risk estimates.
A study found that high blood levels of xylitol were associated with an increased risk of major adverse cardiovascular events. Researchers analyzed data from 17,710 participants and found a dose-dependent relationship between xylitol levels and cardiovascular event rates.
Patients with heart failure, caregivers, and providers are open to mobile health (MIH) adoption, but financial and regulatory challenges hinder its reach and sustainability. MIH programs can reduce ED transports, but their financial viability is constrained by Medicare's transport-based EMS reimbursement structure.
A new study uses machine learning to predict which patients with coronary artery disease will benefit from exercise-based cardiac rehabilitation. The model accurately identifies 'non-responders' using data from cardiopulmonary exercise testing and pulse wave analysis, allowing for tailored treatment plans.
A study from Karolinska Institutet found that older adults with longer meal intervals accumulated chronic diseases more rapidly than those with shorter intervals. The association was strongest among people aged 78 years and older, and was linked to faster accumulation of cardiovascular and neuropsychiatric diseases.
Researchers used an AI tool to analyze health records of 12,701 UK Biobank participants who had experienced a heart attack. The study found three distinct health paths, with 63% developing cardiometabolic conditions and 23% suffering a decline in lung function. The AI tool predicted the health trajectory and identified high-risk groups...
Scientists at King's College London discovered that urolithin A improves heart function, reduces scarring and prevents harmful enlargement of the heart in a type of heart failure. The compound has already been evaluated in human studies and shows a favorable safety profile, offering a promising new treatment target.
A new roadmap for stroke recovery prioritizes genetic and blood biomarkers to drive precision neuro-rehabilitation and biotherapy. The framework seeks to understand the underlying biology of brain repair after a stroke, with the goal of developing effective biotherapeutics.
Researchers at Karolinska Institutet discovered that gut bacteria convert dietary nitrate and iron into protective molecules, such as dinitrosyl iron complexes, which may improve cardiovascular and metabolic health markers. These findings suggest a previously unknown mechanism by which a specific diet and gut bacteria can promote health.
Nicotine damages the cardiovascular system by binding to receptors in blood vessel walls, suppressing vasodilators, and triggering vessel constriction. Abstinence is the only risk-free option, and e-cigarettes and heat-not-burn devices pose significant cardiovascular risks.
Researchers at Murdoch Children's Research Institute have made a breakthrough in gene therapy, restoring heart function in lab-grown patient heart tissue and mouse models with genetic heart disease. The therapy may also correct other genetic heart diseases, including those caused by the MYH7 gene and TTN truncating variants.
A new study from North Carolina State University found that an AI-enabled digital stethoscope struggled to detect cardiac murmurs and arrhythmias in cats, while performing moderately well in dogs. The researchers emphasize the need for veterinarians to rely on human expertise when using AI-assisted technology.
Insilico Medicine has nominated ISM0900, a potent and selective oral Lp(a) inhibitor, as a preclinical candidate for managing cardiovascular risks. The compound demonstrates rapid onset, excellent oral pharmacokinetics, and superior efficacy in reducing Lp(a) levels.
A meta-analysis of nearly 1,900 studies found that climbing stairs significantly reduces the risk of dying from cardiovascular disease. Regular stair climbing was associated with lower risks of heart-related problems and major cardiovascular conditions such as heart attack, stroke, and heart failure.
A recent study published in JAMA Network Open finds a strong association between gestational diabetes and an increased risk of postpartum cardiovascular, kidney, and metabolic disorders. The research highlights the importance of monitoring and managing gestational diabetes to prevent long-term health consequences for mothers.
A study from Karolinska Institutet found that people treated with modern NOAC blood-thinning medicines experienced a slower rate of cognitive decline compared to those receiving warfarin or no anticoagulant treatment. This was associated with lower risk of other health problems, including death, stroke, and fractures.
The open-source image analysis pipeline accurately measures brain tissue changes in animal models, reducing variability among thousands of scans. The tool has the potential to improve early-stage evaluation of new therapies for acute ischemic stroke.
Dysregulated neutrophils may play a key role in persistent low-grade inflammation seen in chronic coronary syndrome. Researchers found that neutrophils from patients with stable coronary artery disease do not die as they should, persisting and remaining highly active.