Articles tagged with Cardiovascular Disorders
A new study found that a polypill combining medications for heart failure improved heart function, symptoms, and quality of life. Adults with reduced ejection fraction heart failure who took the combined medication had fewer hospitalizations and greater medication adherence than those taking individual pills.
Researchers found that an earlier blood transfusion may reduce the risk of heart failure and irregular heartbeat in adults with heart disease. The study suggests that waiting until hemoglobin levels are low before transfusing blood may not be the best strategy for high-risk patients.
A new study found that standard medical care, including blood thinners, is the better choice for older people with irregular heart rhythms who are at high risk of stroke and bleeding. The catheter-based procedure was non-inferior to medical therapy in reducing stroke risk but caused more bleeding in higher-risk patients.
Using stress cardiac MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life for people with suspected angina. The test can help identify small vessel problems that may be causing chest pain, which are often under-recognized in women and other groups.
A new study found that adding a PCSK9 inhibitor to a high-intensity cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with ASCVD or diabetes. The study suggests long-term lowering with PCSK9 inhibitors can improve cardiovascular morbidity and mortality over time.
A recent study from Karolinska Institutet has identified a specific protein pattern in the blood that may reflect an increased risk of hereditary atherosclerosis. The research found that certain proteins, such as follistatin and cathepsin D, are significantly elevated in people with a family history of early-onset coronary heart disease.
A new study found that providing healthy, medically tailored meals and fresh produce boxes along with nutrition counseling can improve the quality of life for people with heart failure. The 90-day trial showed significant benefits compared to dietary counseling without food delivery.
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
A recent study found that adults with heart disease who took vitamin D doses tailored to their individual needs reduced their risk of another heart attack by more than half. The study also showed that supplementation appeared beneficial for preventing heart attack specifically.
Researchers found that drinking a cup of caffeinated coffee per day reduced Atrial Fibrillation (A-Fib) by 39% in patients with persistent atrial fibrillation. The study, funded by the National Institutes of Health, suggests that coffee may be protective against A-Fib and could potentially reduce blood pressure.
A large international study found that opening all blocked arteries with stents significantly reduces the risk of death from cardiovascular causes and future heart attacks compared to treating only the culprit artery. This study provides strong evidence for complete revascularization as a life-saving procedure.
Researchers found olezarsen significantly reduced acute pancreatitis incidence by 85% in patients with severely elevated triglyceride levels. The drug also lowered triglyceride levels below 500mg/dL in over 85% of participants.
The American College of Cardiology and OpenEvidence are collaborating to integrate AI technology into clinical workflows, enhancing patient care and outcomes. The partnership aims to translate scientific discovery into clinical implementation, providing clinicians with timely and accurate medical evidence.
A study published in JAMA finds that using different methods to estimate glomerular filtration rate (eGFR) can lead to significant discrepancies, particularly for those with chronic kidney disease. The findings suggest that cystatin C-based eGFR may be more accurate in predicting clinical outcomes.
A new international study confirms that drug-coated balloons can effectively treat larger narrowed blood vessels, offering a safer alternative to stents. The findings validate the method developed by Professor Bruno Scheller and demonstrate its efficacy in treating arteries with diameters larger than 2.75 mm.
A recent study from Houston Methodist reveals how Alzheimer's can disrupt the connection between nerves and blood vessels in fat tissue, worsening heart and metabolic conditions. The research highlights a potential link between neurodegeneration and cardiovascular and metabolic disorders.
The American Heart Association's inaugural CarePlan Challenge recognizes innovators who create digital solutions that transform preventive care, improve disease management and enhance patient engagement. The selected solutions showcase integration of the Association's science-based CarePlans and other digital tools.
MIT engineers have developed a programmable drug-delivery patch that can reduce damaged heart tissue by 50 percent and improve cardiac function. The patch is designed to release different drugs at specific times, promoting healing and regeneration of cardiac tissue.
A large-scale study published in the European Heart Journal found no increased risk of heart attack and stroke among transgender women taking hormone oestradiol. In contrast, transgender men using testosterone have a higher risk due to factors such as high blood pressure and poorer cholesterol levels.
The American Heart Association brought hypertrophic cardiomyopathy and Hands-Only CPR awareness to a historic college football game, aiming to empower young athletes and their families with critical knowledge. The organization aims to double cardiac arrest survival rates by 2030 through its Nation of Lifesavers movement.
The American Heart Association has named five finalists in its Health Tech Competition to present innovative solutions for cardiovascular conditions. The selected companies will showcase their technologies during the 2025 Scientific Sessions, where a panel of expert judges will evaluate their presentations.
Researchers have found that atrial electromechanical dissociation (AEMD) can predict stroke risk in people with transthyretin amyloid cardiomyopathy, even when the heart rhythm appears normal. A non-invasive assessment tool may help identify those at increased risk and guide earlier conversations about preventive strategies.
A study found that long-term use of melatonin supplements may increase the risk of heart failure, hospitalization, and death in adults with chronic insomnia. The research analyzed data from a large international database and found consistent and significant increases in serious health outcomes, even after balancing for other risk factors.
A preliminary study found that low-dose aspirin use was associated with a lower risk of major cardiovascular events, including heart attacks and strokes, among adults with Type 2 diabetes. The analysis of 11,500 individuals over 10 years showed that consistent aspirin use led to significant reductions in cardiovascular event rates.
A study found that following steps to improve cardiovascular health can reduce the risk of mild cognitive impairment and dementia among people with Type 2 diabetes. Maintaining optimal cardiovascular health may protect brain health even for individuals with a high genetic risk for dementia.
Researchers found that combining three biomarkers – lipoprotein(a), remnant cholesterol, and high-sensitivity C-reactive protein – can reveal a nearly three-fold increase in heart attack risk. This combination approach may aid health care professionals in identifying individuals with high-risk profiles earlier.
Researchers developed an AI algorithm that accurately diagnosed multiple structural heart diseases from single-lead ECG sensors on smartwatches. The algorithm was trained on over 266,000 12-lead ECG recordings and prospectively validated in a real-world setting.
Cardiac rehabilitation significantly improves short and long-term recovery for heart surgery patients, but women participate less than men due to barriers such as lower referral rates, clinician bias, and caregiving responsibilities. The American Heart Association scientific statement calls for targeted interventions to improve enrollm...
A naturally occurring gene called Cyclin A2, normally silenced in humans, can make new functioning heart cells and aid in the heart's repair. The breakthrough discovery could lead to new techniques for repairing damaged hearts as an alternative to transplants or implanted cardiac devices.
A study found a nearly linear relationship between nighttime light exposure and an increased risk of heart disease. The research suggests that reducing exposure to excessive artificial light at night can counteract the effects and may be a public health concern.
A new study found that combining GLP-1 receptor agonist medications with healthy lifestyle habits significantly reduces the risk of major adverse cardiovascular events, including heart attacks and strokes. The research suggests that adopting multiple healthy behaviors can lower cardiovascular risk even further.
The study found that men, Black patients, and those living in low socioeconomic areas were disproportionately affected by the increased amputation rates. The authors emphasize the need for aggressive prevention, early diagnosis, and intensive risk factor management to address the growing burden of diabetes and PAD.
A new resource identifies genetic variants associated with elevated 'bad' cholesterol, a major contributor to heart disease. Clinicians can now predict patient risk for heart attacks and strokes, allowing for prevention and early treatment.
Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.
A new study from the University of Birmingham found that consuming flavanols can preserve blood vessel function in young healthy men during periods of uninterrupted sitting. The researchers tested whether high-flavanol cocoa could prevent FMD declines, and found significant protection against vascular dysfunction.
The Lehigh University team created a computational model to predict the hemodynamic response of patients with AFib, helping tailor neurostimulation dosages. The model validated against clinical data and predicted accurate effects on blood pressure, heart rate, and stroke volume.
Research found acute and chronic viral infections increase risk of heart attacks and strokes, while long-term risks persist for HIV, hepatitis C, and herpes zoster. Vaccination measures, including flu shots, can reduce cardiovascular disease risk by 34%.
The study found that cutting balloon angioplasty is noninferior to intravascular lithotripsy in treating calcified coronary artery disease. The procedure is also less costly, making it a reasonable strategy for managing significantly calcified lesions.
Benjamin Abella, MD, receives Honorary Membership from ERC for his leadership and expertise in cardiac arrest and CPR. He has advanced resuscitation science through numerous clinical studies and publications.
A novel post-translational modification, lactylation, plays a critical role in the pathogenesis of aortic dissection. Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha impairs ATP production and increases reactive oxygen species generation.
A study found that longer accumulations of steps in one go have a greater health benefit than short bouts spread out across the day. Walking continuously for 10-15 minutes per day was associated with lower risk of cardiovascular events and mortality.
A study found that super-high-pressure non-compliant balloons (NCB) are non-inferior to IVL balloon catheters for lesion preparation and stent expansion in severely calcified lesions. The results showed similar safety profiles and efficacy across various patient subgroups.
A new study published in TCT 2025 reveals that at least 4.7 million people aged 65-85 living in the US have moderate or greater valvular heart disease (VHD), and at least 10.6 million have clinically significant VHD. The prevalence of VHD increases with advanced age, highlighting the need for screening and treatment programs.
The merger strengthens CRF's leadership in medtech, integrating Fogarty's expertise in early-stage innovation. The unified platform will accelerate breakthroughs into patient care, driving global progress in cardiovascular medicine.
A large international study found that utilizing sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine DES implantation for treating de novo coronary artery disease. The results showed comparable outcomes, including low rates of cardiac death and target vessel myocardial infarction.
A new sirolimus-eluting balloon has been shown to be noninferior to traditional treatments for in-stent restenosis. The study, presented at TCT 2025, found the balloon to be safe and effective for treating ISR without adding extra layers of stents.
Two researchers will receive the inaugural Jack Sarver Prizes for their work on preventing maternal mortality in Nigeria and identifying a potential therapeutic target for metabolic dysfunction-associated steatotic liver disease and atherosclerosis. The awards recognize Dr. Zainab Mahmoud's study on aspirin prophylaxis for preeclampsia...
The Cardiovascular Research Foundation (CRF) has announced the 2025 SET-10 Rankings, honoring institutions whose groundbreaking research is shaping the future of cardiovascular care. The rankings recognize academic and medical institutions that are advancing the science and improving patient outcomes.
A new study found that bright light exposure at night significantly increases the chances of developing serious heart problems. Women and younger people were especially vulnerable to this impact. The researchers are now calling for more research into lighting guidelines to help reduce night-time light exposure.
Researchers at Karolinska Institutet have developed a system to classify individuals into different risk groups for atherosclerosis based on genetic data. The study identified four distinct risk groups, with one specific gene variant linked to increased cardiovascular risk in those with high predicted risk.
A new study published in The BMJ found that restricting sugar intake during early life is associated with lower risks of heart conditions in adulthood. People exposed to sugar rationing in utero and during their first two years had a 20% reduced risk of cardiovascular disease, as well as slower onset of heart problems.
A large national cohort study found associations between adverse pregnancy outcomes and increased risk of atrial fibrillation up to 46 years later. Women with these outcomes require early preventive actions and long-term clinical follow-up.
The American Heart Association found that nearly 9 in 10 US adults haven't heard of CKM syndrome, a condition affecting heart disease, kidney disease, diabetes, and obesity. The association is providing resources to help people understand the connection between heart, kidney, and metabolic health.
A recent study published in the European Heart Journal found that female bodybuilders are at a high risk of sudden cardiac death, with a mortality rate 20 times higher than amateur athletes. The study also revealed a significant proportion of deaths from suicide and homicide.
Research challenges assumption that severe preeclampsia cases are more dangerous for mothers, finding instead that women with large preterm infants face increased cardiovascular disease risk despite smaller infant size.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Researchers developed innovative blood-based biomarkers to predict long-term blood pressure improvements after bariatric surgery. The study analyzed pre-surgery blood tests and identified top 10 molecules linked to improved blood pressure outcomes.
A potential new drug called RBM20-ASO has been shown to improve cardiac function in a mouse model of heart failure with preserved ejection fraction (HFpEF). The therapy reduces left ventricular stiffness and abnormal thickening of the heart muscle, even in the presence of comorbidities.
A new AI-based risk assessment tool, GRACE 3.0, has shown better predictability of future risk for heart attack patients compared to traditional methods.
Scientists found that CtBP2 levels decrease with age, but are higher in long-lived individuals. This biomarker may estimate the degree of aging and overall health status.