Articles tagged with Cardiovascular Disorders
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Researchers found that low sodium levels can disrupt the heartbeat in patients taking widely used rhythm-control medications like flecainide, increasing conduction risk. Interfering with ephaptic coupling or potassium ion flow reduces heart sensitivity to low sodium when sodium channels are blocked.
The UK Biobank has completed a groundbreaking imaging project, scanning the brains, hearts, abdomens, blood vessels, bones and joints of 100,000 volunteers to understand how diseases develop. The project is already improving patient care in the NHS and beyond, with over 1,300 peer-reviewed scientific papers published based on the data.
Delays in hypertension diagnosis were common, associated with delayed treatment initiation and adverse cardiovascular outcomes. The study highlights the need for earlier identification and intervention to improve treatment and patient outcomes.
A new study suggests that erythritol, commonly used in low-carb products, can alter the function of brain microvascular endothelial cells, leading to increased risk of stroke. The sugar substitute was found to constrict blood vessels and reduce the production of natural clot-busting compounds.
A recent study by Tarang Parekh reveals that 80% of US adults show signs of CKM syndrome, which increases the risk for cardiovascular disease. The condition progresses in stages, with stage 4 being the most dire, characterized by clinical CVD diagnoses such as heart failure and kidney failure.
Heart attacks often don't follow a Hollywood script, says UTA expert Ann Eckhardt. Symptoms can be complex and mild, with discomfort or pressure rather than pain. This misperception leads to delayed medical attention, increasing the risk of negative consequences.
A new Leicester study found that women with type 2 diabetes are nearly twice as likely as men to have hidden heart damage, according to researchers. The study used advanced MRI scans and data from four studies conducted at the NIHR Leicester Biomedical Research Centre.
Scientists are working on a genetic cure for the world's most common inherited heart disease, hypertrophic cardiomyopathy (HCM), with a new gene editing tool. The team aims to correct mutations that cause the disease, which affects 14 million people worldwide.
Researchers highlight a significant gap in detecting symptoms and preventive measures before myocardial infarctions, with distinct differences found between age groups and genders.
Researchers at Lund University have discovered a new signalling pathway that protects against hypertension by activating a compensatory mechanism in blood vessel cells. The study found that the mice were protected against hypertension by activating this pathway, which suggests potential for future complementary blood pressure medicines.
A new AI model developed by Johns Hopkins University researchers accurately identifies patients at high risk for sudden cardiac death, surpassing clinical guidelines in accuracy. The model analyzes long-underused heart imaging and medical records to reveal hidden information about a patient's heart health.
A study of over 2,500 adults aged 50-80 found that nearly 1 in 6 take aspirin for cardiovascular protection without a history of heart disease. Despite revised guidelines reducing aspirin use for primary prevention after age 70, many patients are unaware of the increased risk of bleeding.
Research using cardiac MRI found that long-term exposure to air pollution is associated with early signs of heart damage, including diffuse myocardial fibrosis. The study suggests that fine particulate matter in the air may contribute to changes in the heart structure, potentially setting the stage for future cardiovascular disease.
Researchers aim to replenish the heart's energy reserves by increasing mitochondrial biogenesis, potentially leading to improved recovery rates and longer lives after a heart attack. The project combines synthetic biology tools with animal models and human heart tissue testing.
A new study published in The Lancet found that starting direct oral anticoagulants within four days of a stroke significantly reduces the risk of another stroke due to bleeding or artery blockage. Early treatment also did not increase the risk of bleeding into the brain.
Scientists at The University of Texas at Arlington identified a new enzyme, IDO1, that plays a crucial role in inflammation and cholesterol regulation. By blocking this enzyme, macrophages regain their ability to absorb cholesterol, offering a potential new way to prevent heart disease.
AIMP3 is essential to avoiding mistakes in protein synthesis, not affecting protein production, according to Brown University researchers. The discovery could lead to new treatments for heart diseases linked to homocysteine buildup and has implications beyond the heart.
A new study involving 121 former elite rowers from Australia found that one in five develops atrial fibrillation, a condition that can lead to stroke and heart failure. The researchers identified genetic and clinical tools that enable early preventive strategies, highlighting the paradox that AFib is more common among fit athletes.
Research reveals significant drop in heart attack deaths, while increases observed in deaths from heart failure, arrhythmias, and hypertensive heart disease over the past 50 years. Studies suggest advancements in medical treatment, bystander CPR, and public health initiatives have contributed to these findings.
A large global study found that women who experience severe bleeding after childbirth face an increased risk of cardiovascular conditions, including heart failure and ischemic heart disease, for up to 15 years. The study analyzed data from over 9.7 million women across Europe, North America, and Asia.
A new study found that increasing apolipoprotein M levels can slow or block progression of age-related macular degeneration, a leading cause of blindness in people over 50. The researchers also found that ApoM triggers a signaling pathway that breaks down cholesterol deposits.
Researchers found an increased risk of stroke in women who experienced diabetes, high blood pressure, preterm delivery, or low birth weight during pregnancy. These complications could act as early signals for cardiovascular problems, enabling women to receive help and reduce their risk.
Elevated cortisol levels in preterm fetuses disrupt normal heart development, potentially leading to increased cardiovascular disease risk. Cortisol exposure accelerates heart development in ways that may not be beneficial, ultimately compromising heart health.
Research found that certain heart rate variability patterns can predict future health conditions, including stroke, depression, and cognitive dysfunction. The study suggests that nocturnal HRV provides a unique window into how the body functions during sleep.
Researchers developed a novel amine-functionalized graphene oxide (NGO) membrane reactor for ultrafast synthesis of propranolol, achieving nearly 100% conversion and selectivity in under 4.63 seconds at 23°C. The NGO membrane exhibited higher catalytic flux and turnover frequency compared to the acidic graphene oxide (GO) membrane.
The collaboration aims to co-develop new treatment paradigms and accelerate innovation in cardiac care, with a focus on Asian populations. The partnership will create opportunities for breakthrough research, knowledge exchange, and training for healthcare professionals.
A study published in Neurology Clinical Practice found that people with poor access to food, living in disadvantaged neighborhoods, and lacking strong social support experienced worse outcomes after stroke. Despite these challenges, they had better survival rates, with 78% survival rate three months after stroke and 62% one year after.
A new study from Karolinska Institutet found that infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence. Children with neurological health problems had almost six times the risk of death compared to healthy children.
A study found that healthy sleep habits at age 15, including earlier sleep timing and lower sleep variability, predicted better cardiovascular health at age 22. This suggests that addressing multiple dimensions of sleep health may be crucial for promoting long-term heart health.
High blood pressure typically has no signs or symptoms, according to the CDC. Few U.S. adults can correctly identify what blood pressure reading is considered high (130/80 mmHg). Despite prevalence, many people mistakenly believe high blood pressure always has noticeable symptoms or can be identified by feeling calm and relaxed.
Researchers identified biomarkers like uric acid and bile acids as critical regulators of arterial stiffness and inflammation in adolescents with obesity. These findings provide new avenues for early intervention to prevent the progression of vascular stiffness and cardiovascular disease.
A novel screening approach called VEST uses virtual echocardiography to identify patients at high risk of pulmonary arterial hypertension, a life-threatening form of heart failure. The tool has been shown to generate accurate PAH risk scores without manual calculations and can guide timely referrals for expert care.
A 12-week study found that chickpea consumption improved cholesterol levels, while eating black beans reduced inflammation in adults with prediabetes. The researchers suggest incorporating beans into daily diets as a simple way to reduce chronic disease risk.
Researchers found cardiac deaths exceeded expected levels between 2020 and 2023, with a significant increase in 2020 and 2021. The study suggests potential shortcomings in cardiac care during and after the pandemic.
Researchers at UT Health San Antonio discovered associations between blood lipid levels and Alzheimer's disease risk. Higher small dense cholesterol particles increased risk, while ApoB48 levels were associated with lower risk.
Researchers found that intestinal bacteria and their metabolites can accelerate blood vessel aging and trigger cardiovascular disease. The breakdown product of phenylalanine, phenylacetic acid, accumulates with age and leads to senescence of endothelial cells.
The study reveals alarming increases in mental disorders, cardiovascular diseases, smoking, and road injuries across the ASEAN region. Mental disorders affect over 80 million people, while cardiovascular diseases claim 37 million lives, with smoking and road injuries exacerbating the problem.
This novel treatment approach yields better weight loss maintenance and cardiovascular risk outcomes compared to standard-of-care treatment. Patient-delivered lifestyle intervention combined with peer support significantly improves weight loss and reduces cardiovascular risk.
A new study from Mass General Brigham found that patients with diabetes who started statin therapy immediately reduced the rate of heart attacks and strokes by one-third compared to those who delayed treatment. The study analyzed data from over 7,000 patients and used artificial intelligence to gather information.
A new study led by Boston University School of Public Health reveals that US excess deaths have been increasing for decades, with working-age adults disproportionately affected. The study found that over 1.5 million 'missing Americans' would have been averted if the US had mortality rates similar to other high-income countries.
Nontraumatic subarachnoid hemorrhage (SAH) is the third most common stroke type, accounting for 5-10% of all strokes. Despite declining age-standardized burden rates, SAH remains a major public health concern globally.
A study found that adults hospitalized for RSV had significantly higher odds of cardiac events compared to those with COVID-19 or influenza. The findings suggest that preexisting cardiovascular risk patients should consider vaccination against respiratory viral infections.
A Monash University study found that rare genetic variants affecting SCFA signalling increase hypertension and cardiovascular disease risk. However, adequate dietary fibre intake mitigates this risk, highlighting the importance of SCFAs in cardio-protection.
Moleculera Biosciences, a precision medicine company, is attracting investors with its technology developed by the University of Oklahoma. The company's diagnostic tests have helped properly diagnose over 16,000 patients and have shown remarkable recoveries in those affected by autoimmune disorders.
The PREVENT calculator improved estimates of heart attack risk when combined with coronary calcium score. Researchers analyzed nearly 7,000 adults and found that the PREVENT score matched the level of calcium buildup according to the CAC score.
A new study found that intensive blood pressure reduction had similar outcomes across educational attainment levels, but high-educated individuals experienced greater cardiovascular risk reductions. The research analyzed data from the SPRINT trial and suggested that unmeasured social factors may play a role in heart health disparities.
A study published in the Journal of Pharmacological Sciences has discovered that ferulic acid can help prevent coronary artery spasms. The compound works by blocking calcium entry into muscle cells and stopping a specific protein from being activated, leading to reduced artery contractions.
A study published in the European Heart Journal found that male bodybuilders have a high risk of sudden cardiac death, with professional bodybuilders facing a more than fivefold increase in risk. The study highlights the need for greater awareness, preventive strategies and policy changes within the bodybuilding community.
Surgeons at Mount Sinai performed the world's first heart-liver-kidney triple organ transplants in New York State, with two patients making full recoveries after the surgeries. The procedures were led by Anelechi Anyanwu and Sander S. Florman and represent a significant milestone in complex organ transplantation.
A study of 1,113 patients aged 65+ found that nearly half had two or three overlapping cardiovascular, kidney, and metabolic conditions, leading to poorer physical function and higher mortality rates. The findings support the need for early identification of vulnerable individuals and risk stratification without advanced diagnostics.
People who sit for more than 14 hours a day may have a higher risk of cardiovascular events or death after treatment for heart attack symptoms. Replacing sedentary time with sleep reduces the risk, according to new research published in Circulation: Cardiovascular Quality and Outcomes.
The USC Parris Longevity Accelerator aims to develop early interventions for age-related diseases, including osteoarthritis and cardiovascular disease, through AI-driven diagnostic tools and targeted therapeutics. The initiative could lead to therapies that preserve mobility and restore strength in older adults.
A new molecular process discovered by researchers contributes to the failure of donor hearts after transplant, but a therapy using medication for high blood pressure has been found to reduce damage. The treatment significantly improves the function of donor hearts and increases their distance in cold storage.
A new study suggests that controlling eight key health risk factors can significantly reduce premature death risk in people with high blood pressure. By addressing these risk factors, researchers found a 40% lower risk of early death and up to 53% less risk of death due to cardiovascular disease.
Two out of five heart failure patients do not see a cardiologist annually, significantly increasing mortality risk. Patients who receive regular cardiology care are 24% less likely to die in the following year, with optimal visits ranging from once to four times per year depending on recent hospitalization and diuretic use.
A new study from Uppsala University found that people with high fitness levels in late adolescence have a lower risk of dying prematurely, but the association between physical fitness and reduced mortality risk may be overstated. The researchers examined data from over 1 million Swedish men and found no significant difference in the ri...
People with critically ill heart disease may benefit from palliative care, which focuses on relieving symptoms and improving quality of life. The new American Heart Association statement suggests integrating palliative care principles into the management of patients with critical cardiovascular illness.
Researchers at Ohio State University discovered that women's hearts beat faster due to higher levels of genes like TBX3 and HCN1. In contrast, men's hearts are more prone to irregular rhythms like atrial fibrillation, linked to inflammation and collagen production.
Researchers found that snus cessation led to a clinically significant rise in blood pressure, averaging 3.7 mm Hg, and weight gain of 1.8 kilos in a group of 33 participants. The study suggests that healthcare professionals should monitor blood pressure after snus cessation, especially for individuals with cardiovascular problems.
A new study found that patients using factor Xa inhibitors experienced significantly fewer cardiovascular problems than those on other anticoagulants. Researchers followed over 1,000 patients aged 80 and above for up to five years, revealing lower rates of heart failure, artery disease, and cardiovascular death.