Articles tagged with Cardiovascular Disorders
Researchers at Keck School of Medicine have identified a new potential treatment target for AARS2-related cardiomyopathy, a rare and fatal heart muscle disease in infants. By targeting the PCBP1 gene, they aim to restore healthier AARS2 function in heart cells and prevent damage.
A study from Umeå University found that visualizing ultrasound images of atherosclerosis, combined with a motivational dialogue, increases motivation to improve lifestyle habits and take preventive medication. This results in lower estimated risk of cardiovascular disease and better development of risk factors over time.
A study from Tulane University found that long-term, untreated syphilis increases the risk of serious cardiovascular issues, including stroke, heart attack, and aortic aneurysm. Adults with syphilis were more likely to develop these problems than similar patients without the infection.
Dr. Karina Yaniv has been appointed as the new Scientific Director of Systemic AngioCardioScience at the Helmholtz Institute for Translational AngioCardioScience (HI-TAC). She aims to expand her research with a focus on translation into clinical applications, and build a bridge between basic and translational cardiovascular research.
A large-scale study linked loneliness to an increased risk of degenerative heart valve disease, including aortic valve stenosis and mitral valve regurgitation. Researchers say addressing loneliness could help delay disease progression and reduce the clinical and economic burden of valvular heart disease.
Research suggests that exercising at a time that matches an individual's natural chronotype (morning or evening alertness) can lower cardiovascular disease risk. The study found that chronotype-aligned exercise improved blood pressure, fasting glucose, cholesterol levels, and sleep quality more effectively than mismatched timing.
A randomized trial demonstrated that Left Bundle Branch Area Pacing (LBBAP) is an effective strategy for cardiac resynchronisation in patients with heart failure. LBBAP was found to reduce device-related complications and procedure times compared to biventricular pacing.
Researchers have identified a critical molecular mechanism that shuts down the heart's repair system after cardiac arrest, leaving it unable to recover. The study aims to develop new treatments for devastating medical conditions such as heart attack and stroke during major surgery.
A study of over 600,000 people found that early weight gain is associated with a higher risk of dying from various diseases, particularly cardiovascular disease and type 2 diabetes. Weight gain during adulthood also increases the risk of premature death, especially for those who develop obesity at a younger age.
Combining resistance training and aerobic exercises significantly enhances aerobic fitness, muscle strength, and walking distance in heart failure patients. Adding resistance training to aerobic workouts increases muscle strength more than exercising aerobically alone.
A team-based program in community health clinics helped low-income patients reduce their blood pressure more than standard care alone. After 18 months, patients in the team-based program saw a significant drop in systolic blood pressure and showed better adherence to hypertension treatment.
A study of over 1500 patients with brain bleeds found that brain swelling in the first 24 hours and within 72 hours increased the risk of death or disability. Early intervention could potentially limit brain damage and improve recovery after stroke.
A new study by University Hospitals Harrington Heart & Vascular Institute highlights the long-term impact of preventive heart and vascular care. The study shows a significant decline in cardiovascular mortality rates after investments in local cardiac care, with notable reductions among older age groups.
Research published in Ethnicity & Disease found that self-employed Hispanic women report less high blood pressure, obesity, and poor health compared to their salaried counterparts. They were also more likely to exercise, with a nearly 11% higher rate of physical activity.
Researchers developed a method to estimate vascular age from consumer wearables' PPG signals, predicting accurate results with a mean error of six to seven years. The technique uses a deep learning model and may lead to earlier detection of cardiovascular risk and more effective preventive care.
Treatment with i.v. furosemide plus HSS significantly decreased serum levels of inflammatory biomarkers IL-6, sST2, hsTnT, galectin-3, and NT-proBNP. The study found that this combination therapy modulated some miRNA expression and was associated with reduced miR181b expression compared to furosemide alone.
A new study by Lund University researchers found that genetic risk scores can predict coronary artery disease even before diabetes onset. The study identifies a group at high risk of developing both conditions, offering potential for early detection and prevention.
The new guidelines introduce five clinical categories to capture PE severity, emphasizing follow-up care and treatment considerations. Despite advances in diagnosis and treatment, PE remains a serious condition with substantial risk, highlighting the need for continued research and improvement.
The American Heart Association and NFL will welcome thousands to train in Hands-Only CPR at the NFL Draft, a lifesaving skill that can double or triple a person's chance of survival. This effort aims to empower fans, families, and communities with a simple yet powerful message: be ready to save a life.
Researchers created personalized digital twins of patients' hearts to improve cardiac ablation outcomes for life-threatening arrythmias. The approach resulted in faster and more accurate procedures, reducing recurrences of arrythmias and increasing success rates compared to traditional methods.
A new study found that older people who forego necessary dental procedures due to financial barriers may experience heart failure, a heart attack, a stroke, or dementia. The researchers suggest that alleviating upstream factors such as financial constraints could prevent chronic disease.
Researchers found a clear connection between oral health and kidney health, with immune dysregulation and systemic inflammation driving the relationship. The study highlights the need for physicians to integrate oral and renal health into clinical care systems.
A new study from the University of Oulu suggests that large swings in bedtime could double the risk of serious cardiac events. Inconsistent bedtimes were strongly associated with a higher risk of major cardiovascular events, especially among those who get less than eight hours of sleep.
The program aims to improve the ability to predict, prevent and treat health complications in people living with Fontan circulation. Clinicians and researchers will generate scientific and clinical insights to develop tools guiding care for patients with Fontan circulation.
Early and continuous acoramidis treatment resulted in sustained incremental reductions in all-cause mortality, cardiovascular-related mortality, and first cardiovascular hospitalization. The findings support the importance of early and continuous long-term treatment with acoramidis in transthyretin amyloid cardiomyopathy.
Dr. Roxana Mehran was appointed President of the American College of Cardiology, focusing on innovation, equity, and global collaboration to advance cardiovascular care. She aims to improve heart health for all through partnerships with major organizations.
Research found that people who spend a higher proportion of their total physical activity doing vigorous activity have substantially lower risks of all eight serious health conditions. The benefits of vigorous activity remained even when the amount of time was modest.
Patients with atrial fibrillation have a higher risk of adverse cardiovascular events, including stroke, heart attack, and cardiac arrest. Serum neurofilament light chain levels can serve as a biomarker for cardiovascular risk in these patients.
A new trial found that using a microaxial flow pump before and during cardiac stenting procedures for high-risk heart attack patients with severe heart attacks did not reduce heart damage. The study, published in the Journal of the American College of Cardiology, also showed increased bleeding complications.
A clinical trial found that intensive cholesterol-lowering therapy reduced the risk of cardiovascular events by 31% in high-risk patients with diabetes. The treatment, evolocumab, lowered LDL-C levels by approximately 60%, and was well-tolerated.
The MOMENTUM study found that 27% of patients with resistant hypertension have hypercortisolism, a condition characterized by elevated cortisol levels. This finding suggests that hypercortisolism may be an underlying cause of resistant hypertension, which impacts nearly 10 million patients in the US.
In high-risk patients without known significant atherosclerosis and with diabetes, evolocumab significantly reduced the risk of a first major cardiovascular event. The study found that evolocumab was effective in preventing cardiovascular events in these patient populations.
A new study from Tulane University found that women with high predicted cardiovascular risk face nearly double the risk of hip fracture. The association was stronger in women under 65, and higher cardiovascular risk was linked to fractures in weakened bones in major areas.
A review highlights the importance of healthy lifestyles in reducing the risk of cardiovascular disease and type 2 diabetes. Adhering to optimal lifestyle factors, such as a heart-healthy diet, regular physical activity, and adequate sleep, can dramatically lower disease incidence.
A study found that late sleep schedules are linked to unhealthy eating habits, including increased calorie intake and snacking, as well as reduced physical activity, particularly during school hours. The researchers suggest that parents should pay attention to their children's sleep timing during adolescence.
A UTEP study reveals that six weeks of boxing training can reduce blood pressure and improve vascular function in young adults with elevated blood pressure or Stage 1 hypertension. The results show significant reductions in systolic and diastolic blood pressure, comparable to those achieved through medication.
The study developed a novel multi-task deep LASSO algorithm that identified six core clinical indicators, establishing four stable MASLD subtypes with distinct characteristics. The classification system enables targeted interventions, prioritizing fibrosis screening and aggressive cardiorenal protection for specific subgroups.
A study of over 14 million cardiovascular deaths found that colder temperatures are responsible for significantly more heart-related deaths than milder months. The optimal temperature for heart health is 74°F, with temperatures under this point accounting for approximately 40,000 deaths each year.
A Rutgers Health study found that children born to mothers with premature placental separations are three times more likely to develop or die from cardiovascular disease. This risk is higher among those younger than 12 months old, and pregnant women over 35 or experiencing twin pregnancies are also at increased risk.
A new study by Finnish researchers found that lower hemoglobin levels within the normal range may be beneficial for glucose metabolism and cardiovascular health. The study, conducted on 64 adults, revealed an association between lower hemoglobin levels and improved physical fitness, heart health, and reduced liver fat.
A new study in the Journal of the American Heart Association found that children born to mothers with placental abruption are at a higher risk of developing heart disease or dying from cardiovascular disease by age 28. The risk was approximately 4.6 times higher compared to those born without this complication.
A new study published in Journal of the American College of Cardiology found that digital CBT significantly reduced cardiac-related anxiety and improved patients' quality of life and physical function after a heart attack. The treatment showed stable benefits up to one year after completion.
A study found that high screen time and low physical activity are strongly linked with cardiovascular risk among young adults. Screen time was independently associated with markers of cardiovascular risk, even after accounting for differences in daily physical activity.
The 2026 Semmelweis–Richter Journalism Award invites journalists to submit work highlighting critical health issues, particularly cardiovascular therapies. The prize fund is €45,000, with winners announced in July 2026.
A study by Cincinnati Children's Hospital Medical Center and the eMERGE network found that sharing genetic disease risk information with patients can be done responsibly, with a 70% success rate. The team shared results with over 24,000 people using various methods, including one-to-one conversations for those with higher-risk findings.
Researchers found that exercise and aggressive cardiovascular risk reduction improved heart health, but did not produce measurable cognitive benefits over two years in older adults at risk for Alzheimer's disease. The study highlights a critical gap between vascular risk reduction and brain health.
A Korea University study reveals that liver metabolic disease is a key risk factor for heart failure in older adults with atrial fibrillation, with MASLD having the lowest risk and ALD carrying the highest risk. The study highlights the importance of liver health in cardiovascular disease management.
Research shows combining small improvements in sleep, diet quality, and physical activity can significantly reduce major cardiovascular events. Making modest shifts in daily routines, such as sleeping more, eating more vegetables, and exercising more, were associated with a 10% reduction in risk.
A multicenter randomized clinical trial found no significant differences in cognitive improvement between exercise, intensive pharmacological reduction of cardiovascular risk factors, or both in older adults. The study results challenge current recommendations on lifestyle modifications for dementia prevention.
A cluster randomized controlled trial found integrating social risk alerts improved blood pressure control by increasing screenings for social risks. Intervention clinics showed a modest increase in odds of blood pressure control over time.
Researchers at King's College London have been awarded £191,000 to enhance the prediction of aortic coarctation by adapting their established biomarker from MRI to ultrasound. The goal is to improve the accuracy of CoA diagnosis before birth using routine 2D scans.
Researchers developed a new multiview DNN structure to capture complex 3D anatomy and physiology from multiple imaging views, improving diagnostic accuracy for cardiovascular conditions. The approach demonstrated better performance than single-view DNNs and provided a viable alternative for other medical imaging modalities.
The updated guideline consolidates evidence-based recommendations for managing dyslipidemias, offering a comprehensive approach to lower risk of atherosclerotic cardiovascular disease. The guideline recommends earlier intervention through healthy lifestyle changes and considers the use of a new cardiovascular disease risk calculator, P...
A new study finds that adults with prediabetes and hypertension who have subclinical heart injury or stress are at increased risk of heart failure. The study highlights an at-risk population that can be identified using common cardiac biomarkers and emphasizes the importance of preventive care.
Women with cardiometabolic risk factors such as type 2 diabetes and high waist circumference face a higher risk of liver fibrosis, with rates increasing 11-fold and 2.8-fold compared to men. The study highlights the importance of managing these risk factors for liver health beyond heart disease prevention.
Research reveals altered brain networks in newborns with congenital heart disease, which may be linked to sensory perception, movement, and social behavior. After corrective surgery, these brain networks are improved, suggesting that cardiac surgery can improve brain health.
A new study published in the Hypertension journal found that women who experience pregnancy complications may face an increased risk for cardiovascular disease later in life. Higher stress levels during and after pregnancy are associated with higher blood pressure levels 2-to-7 years after delivery.
A study published in the European Heart Journal found that AI analysis of mammograms can predict the risk of serious heart disease in women. Women with mild calcification were 30% more likely to suffer serious cardiovascular disease, while those with severe calcification were two to three times more likely.
A study analyzing over 100 million people found that recreational drugs increase stroke risk, with cocaine and amphetamines linked to double and triple the risk of stroke, respectively. Cannabis use was also associated with an increased risk, particularly among young users.
The European Society of Cardiology has launched new guidelines to support women with cardiovascular disease in making informed decisions about pregnancy and birth. The guidelines aim to improve patient safety and outcomes, recommending a multidisciplinary Pregnancy Heart Team and shared decision-making processes.