The Cardiovascular Research Foundation (CRF) has announced the 2025 SET-10 Rankings, honoring institutions whose groundbreaking research is shaping the future of cardiovascular care. The rankings recognize academic and medical institutions that are advancing the science and improving patient outcomes.
A new study found that bright light exposure at night significantly increases the chances of developing serious heart problems. Women and younger people were especially vulnerable to this impact. The researchers are now calling for more research into lighting guidelines to help reduce night-time light exposure.
SourceFlinders University·JournalJAMA Network Open·TypeData/statistical analysis·DateOct 23, 2025
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Researchers at Karolinska Institutet have developed a system to classify individuals into different risk groups for atherosclerosis based on genetic data. The study identified four distinct risk groups, with one specific gene variant linked to increased cardiovascular risk in those with high predicted risk.
SourceKarolinska Institutet·JournalCardiovascular Research·DateOct 22, 2025
A new study published in The BMJ found that restricting sugar intake during early life is associated with lower risks of heart conditions in adulthood. People exposed to sugar rationing in utero and during their first two years had a 20% reduced risk of cardiovascular disease, as well as slower onset of heart problems.
SourceBMJ Group·JournalThe BMJ·TypeObservational study·DateOct 22, 2025
A large national cohort study found associations between adverse pregnancy outcomes and increased risk of atrial fibrillation up to 46 years later. Women with these outcomes require early preventive actions and long-term clinical follow-up.
The American Heart Association found that nearly 9 in 10 US adults haven't heard of CKM syndrome, a condition affecting heart disease, kidney disease, diabetes, and obesity. The association is providing resources to help people understand the connection between heart, kidney, and metabolic health.
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A recent study published in the European Heart Journal found that female bodybuilders are at a high risk of sudden cardiac death, with a mortality rate 20 times higher than amateur athletes. The study also revealed a significant proportion of deaths from suicide and homicide.
SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateOct 20, 2025
Research challenges assumption that severe preeclampsia cases are more dangerous for mothers, finding instead that women with large preterm infants face increased cardiovascular disease risk despite smaller infant size.
SourceThe University of Bergen·JournalPaediatric and Perinatal Epidemiology·TypeData/statistical analysis·DateOct 20, 2025
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
SourceEuropean Society of Endocrinology·TypeCommentary/editorial·DateOct 17, 2025
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Researchers developed innovative blood-based biomarkers to predict long-term blood pressure improvements after bariatric surgery. The study analyzed pre-surgery blood tests and identified top 10 molecules linked to improved blood pressure outcomes.
SourceKeck School of Medicine of USC·JournalHypertension·TypeData/statistical analysis·DateOct 17, 2025
A potential new drug called RBM20-ASO has been shown to improve cardiac function in a mouse model of heart failure with preserved ejection fraction (HFpEF). The therapy reduces left ventricular stiffness and abnormal thickening of the heart muscle, even in the presence of comorbidities.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalCardiovascular Research·TypeExperimental study·DateOct 17, 2025
A new AI-based risk assessment tool, GRACE 3.0, has shown better predictability of future risk for heart attack patients compared to traditional methods.
SourceUniversity of Leicester·JournalThe Lancet Digital Health·TypeSurvey·DateOct 16, 2025
Scientists found that CtBP2 levels decrease with age, but are higher in long-lived individuals. This biomarker may estimate the degree of aging and overall health status.
SourceUniversity of Tsukuba·JournalNature Aging·DateOct 16, 2025
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This study found that GLP-1RAs and SGLT2is offer the greatest cardiovascular benefits for adults with type 2 diabetes. The magnitude of benefit depends on baseline age, atherosclerotic cardiovascular disease, heart failure, and kidney impairment.
SourceJAMA Network·JournalJAMA Network Open·DateOct 15, 2025
A new scientific statement from the American Heart Association details differences in cardiac rehabilitation access, participation, and outcomes for women compared to men. The statement suggests evidence-based strategies to increase referral and completion rates for cardiac rehab programs among women with cardiovascular disease.
SourceAmerican Heart Association·JournalCirculation·DateOct 14, 2025
A comparative effectiveness study found that liraglutide, semaglutide, and dulaglutide have similar risks for kidney and cardiovascular outcomes in veterans with type 2 diabetes. Head-to-head trials are needed to confirm these findings.
SourceJAMA Network·JournalJAMA Network Open·DateOct 13, 2025
A team of Stanford investigators created a liquid biopsy using cell-free mRNA to diagnose ICI-related myocarditis, enabling tissue- and cell type-specific gene expression profiling. The study identifies a panel of genes associated with the immune response and heart tissue damage, allowing for early detection and treatment adjustment.
SourceStanford Cardiovascular Institute·JournalJournal of Clinical Investigation·DateOct 10, 2025
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A 6-year cohort study found that people living in rental flats and owner-occupied detached houses face higher risks of cardiovascular death compared to those in owner-occupied flats. Improving housing quality to address colder indoor temperatures could lower cardiovascular mortality, particularly among men.
SourceInstitute of Science Tokyo·JournalBMJ Public Health·TypeData/statistical analysis·DateOct 10, 2025
Dr. Amit Khera, a leading expert in preventive cardiology, will receive the 2025 Chairman’s Award for his groundbreaking clinical studies and contributions to the field of cardiovascular risk assessment. He is recognized for his tireless efforts to strengthen the American Heart Association's Scientific Sessions.
Dr. Emelia Benjamin will receive the award for her sustained record of excellence in teaching and mentoring early- and mid-career clinicians and researchers. Her research focuses on atrial fibrillation, mobile health, inflammation, and chronic pain.
A new study found that cardiovascular-related complications during pregnancy affect approximately 15% of pregnancies, with increases seen across all age groups. The rise in health risk factors before and during pregnancy drives these complications, emphasizing the importance of early identification and prevention strategies.
SourceAmerican Heart Association·JournalCirculation·DateOct 6, 2025
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A new study from the University of Copenhagen enables researchers to investigate the cause of heart diseases by analyzing thousands of proteins in heart tissue. This groundbreaking method reveals molecular patterns characteristic of heart diseases.
SourceUniversity of Copenhagen·JournalNature Cardiovascular Research·DateOct 2, 2025
The American Heart Association has acquired the Cardiometabolic Center Alliance program, strengthening efforts to provide holistic management of cardiovascular, kidney, and metabolic health. This partnership aims to expand patient-centered care and improve outcomes for patients with cardiometabolic disease.
Dr. Judith Hochman will receive the 2025 Research Achievement Award for her significant research on revascularization and women's cardiovascular health. Her work has directly impacted clinical practice guidelines, particularly in ischemic heart disease.
A higher cumulative cardiovascular health score in young adulthood is associated with reduced risk of cardiovascular disease and kidney events in midlife. The study emphasizes the importance of early life prevention efforts.
SourceJAMA Network·JournalJAMA Cardiology·DateOct 1, 2025
Research presented at the European Emergency Medicine Congress finds that doctors and nurses are more accurate than AI in triaging patients in emergency departments. While AI showed some promise in flagging critical cases, its overall accuracy was lower than clinicians' across most metrics.
SourceEuropean Society for Emergency Medicine (EUSEM)·TypeSurvey·DateSep 30, 2025
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The Society for Cardiovascular Angiography & Interventions calls for Medicaid payment parity, fairer valuation of CHD procedures, and new compensation models to support care for children and adults with congenital heart disease. This policy statement aims to improve outcomes by addressing economic inequities in the healthcare system.
SourceSociety for Cardiovascular Angiography and Interventions·DateSep 30, 2025
A large-scale study analyzing health records for over 9 million adults in South Korea and nearly 7,000 people in the U.S. found that more than 99% had at least one risk factor before their first cardiac event. High blood pressure was the most common culprit, affecting over 95% of patients.
SourceNorthwestern University·JournalJournal of the American College of Cardiology·DateSep 29, 2025
Dr. Megan McLaughlin's research highlighted critical gaps in postpartum care for individuals with hypertensive disorders of pregnancy, a major risk factor for future cardiovascular disease. Her study confirms missed opportunities to improve long-term heart health in a high-risk population.
A retrospective study found that radiation therapy controlled ventricular tachycardia with fewer complications than standard catheter ablation. Radiation therapy was similarly effective in controlling arrhythmia and showed lower serious side effects, especially in the early time window.
SourceAmerican Society for Radiation Oncology·DateSep 29, 2025
Researchers evaluated over 3,000 ischemic stroke patients and found that telestroke patients were 1.6 times more likely to receive clot-busting drugs, but took nearly seven minutes longer to receive treatment after arriving at the hospital. The study highlights clear gaps in timely treatment for these patients.
SourceMichigan Medicine - University of Michigan·JournalJAMA Network Open·TypeObservational study·DateSep 26, 2025
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A study published in Journal of Internal Medicine found that people with moderate to high levels of albumin in their urine have a higher risk of developing dementia. The researchers discovered an association between albuminuria and increased risk of dementia, independent of kidney function.
SourceKarolinska Institutet·JournalJournal of Internal Medicine·DateSep 23, 2025
Dr. Daniel Lackland, a global leader in hypertension research, will receive the 2025 Population Research Prize for his population-level research on hypertension and cardiovascular disease. The prize recognizes his efforts to address gaps in cardiovascular disease outcomes, particularly among underserved communities.
A new study found significant racial disparities in the care of patients with ST-elevation myocardial infarction (STEMI) in Florida. Hispanic and non-Hispanic Black patients were less likely to receive percutaneous coronary intervention (PCI), a recommended treatment, compared to non-Hispanic white patients. This disparity resulted in ...
SourcePenn State·JournalJAMA Network Open·TypeData/statistical analysis·DateSep 19, 2025
A recent study analyzing data from the Mexican National Health and Nutrition Surveys (2016-2023) found that cardiovascular disease risk increased in Mexico between 2016 and 2023. The average 10-year CVD risk was estimated at 9.5% using region-specific tools, highlighting the need for accurate models to predict local disease burden.
New research finds that GLP-1 receptor agonists (GLP-1RAs) significantly reduce the risk of death and major cardiovascular events in psoriasis patients. GLP-1RAs also show promise in reducing alcohol and substance abuse, with a 65% lower risk of alcohol abuse.
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The report makes recommendations for diagnosing, treating and preventing serious heart and blood vessel complications linked to the virus. Structured cardiac rehabilitation programmes are also recommended to prevent long-term problems after infection and aid recovery from long Covid.
SourceUniversity of East Anglia·JournalEuropean Journal of Preventive Cardiology·TypeSystematic review·DateSep 17, 2025
A large-scale U.S-based randomized trial shows that intensive lifestyle changes can significantly improve global cognition in older adults at high risk of cognitive decline. The intervention emphasized regular physical activity, healthy diet, cognitive stimulation, and social engagement, leading to clinically meaningful improvements. T...
SourceFlorida Atlantic University·TypeCommentary/editorial·DateSep 16, 2025
Mobile integrated health showed promise in improving outcomes for women and younger patients hospitalized for heart failure, particularly reducing hospital readmissions. Younger patients (<70) and women had better health status, with MIH associated with lower risk of readmission and heart failure admission.
SourceColumbia University Irving Medical Center·JournalJAMA Internal Medicine·DateSep 15, 2025
The American Heart Association and American Medical Association recognize 2,307 health care organizations for their efforts in tackling high blood pressure through the Target: BP initiative. This effort has impacted over 10 million adults with hypertension.
Meta Quest 3 512GB
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Researchers identified a long non-coding RNA called CARMN as a surprising new treatment target for chronic limb-threatening ischemia. The study found that blocking the protein HHIP, controlled by CARMN, improves blood flow and tissue healing in patients with CLTI.
SourceMass General Brigham·JournalJournal of Clinical Investigation·TypeExperimental study·DateSep 12, 2025
Ves-GAN, an unsupervised vessel-targeted denoising framework, significantly improves LDCTA imaging by minimizing noise while preserving intricate vascular structures. This innovation enhances diagnostic accuracy in cardiovascular disease diagnosis, directly impacting patient outcomes.
SourceBMEF (BME Frontiers)·JournalBME Frontiers·TypeExperimental study·DateSep 11, 2025
Dr. Collet joins CRF to accelerate integration of cutting-edge research into clinical practice and expand global leadership in cardiovascular education. He will lead efforts to unify translational science, technological innovation, and education.
SourceCardiovascular Research Foundation·DateSep 9, 2025
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Graz researchers investigate homocysteine's impact on the aorta, finding elevated levels lead to stiffer and less elastic vessels. This discovery contributes to understanding of cardiovascular diseases like atherosclerosis.
SourceGraz University of Technology·JournalActa Biomaterialia·TypeExperimental study·DateSep 9, 2025
Researchers found that at-home blood pressure cuffs and texted reminders can significantly improve blood pressure control in patients struggling with hypertension. The study involved mailing cuffs to patients and providing them with texted reminders, resulting in a 35% improvement rate compared to 21% for those without home cuffs.
SourceUniversity of Pennsylvania School of Medicine·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateSep 9, 2025
Emphysema detected on low-dose chest CT scans in asymptomatic adults increases mortality risk over a 25-year follow-up period. The study found that emphysema severity is associated with higher COPD and cardiovascular disease mortality rates, suggesting it as a distinct disease entity linked to poorer health outcomes.
SourceRadiological Society of North America·JournalRadiology·DateSep 9, 2025
A new study found that nearly half of all adults in the U.S. have high blood pressure, and inaccurate images of blood pressure measurement contribute to potentially wrong conclusions about their blood pressure levels. The study highlights the importance of using accurate images to demonstrate proper technique for measuring blood pressure.
SourceAmerican Heart Association·JournalHypertension·DateSep 8, 2025
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A cohort study found GLP-1 RAs offer body mass index-dependent cardiovascular benefits and consistent kidney protection for type 2 diabetes patients. The study suggests BMI stratification is crucial for guiding treatment decisions.
SourceJAMA Network·JournalJAMA Network Open·DateSep 8, 2025
IRB Barcelona researchers discovered a new strategy to combat obesity by activating brown fat, boosting energy expenditure and improving metabolic health. The approach, driven by Neuritin 1 protein, increased energy burning without affecting food intake or physical activity.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalNature Communications·DateSep 4, 2025
A new study published in JAMA Network Open found that older adults living in flood-hit areas in New Jersey faced a 5% higher risk of heart disease for up to five years after Hurricane Sandy's landfall. Flooded ZIP code areas had lower median incomes and higher area deprivation index scores, which are linked to worse health outcomes.
SourceWeill Cornell Medicine·JournalJAMA Network Open·DateSep 3, 2025
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Patients with atrial fibrillation who live in neighborhoods with poor access to full-service grocery stores face sharply higher odds of stroke and death. Food desert residence is linked to a 2.21-times higher risk of ischemic stroke and a 3.84-times higher risk of death over five years.
SourceTulane University·JournalJACC Advances·DateSep 3, 2025
New research from the American Heart Association reveals that most people with atrial fibrillation (AFib) are unaware of the condition before being diagnosed. The study found that AFib patients reported experiencing an average of three symptoms before receiving a diagnosis, highlighting the importance of recognizing early warning signs...
A study by Minttu Venetkoski found that pre-eclampsia increases the risk of ischaemic heart disease and stroke by approximately 1.5-fold. Women with a history of pre-eclampsia are advised to inform their doctors, as this can help mitigate cardiovascular risks during menopause.
SourceUniversity of Helsinki·TypeObservational study·DateSep 3, 2025
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Augsburg researchers identify reticulated platelets as key players in blood clot formation, providing promising therapeutic approaches. The study's findings could lead to personalized platelet inhibition and tailored therapies.
SourceUniversity of Augsburg·JournalEuropean Heart Journal·TypeExperimental study·DateSep 2, 2025
Researchers analyzed data from over 90,000 patients with heart failure and obesity to show that GLP-1 medications can significantly reduce the risk of hospitalization due to heart failure and all-cause mortality. The study found a greater than 40% reduction in these outcomes compared to a placebo group.
SourceMass General Brigham·JournalJAMA·TypeRandomized controlled/clinical trial·DateSep 2, 2025
Researchers found that diabetes directly affects the heart's structure and energy production in humans for the first time. Diabetes causes distinct molecular changes to heart cells and structural changes to the muscle, particularly in patients with ischaemic cardiomyopathy.
SourceUniversity of Sydney·JournalEMBO Molecular Medicine·TypeExperimental study·DateSep 2, 2025
A new study published in The New England Journal of Medicine and the European Heart Journal finds that beta blockers, commonly prescribed after a heart attack, provide no clinical benefit for patients with preserved heart function. Women treated with beta blockers had a higher risk of death, heart attack, or hospitalization for heart f...
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateAug 30, 2025
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A Phase III clinical trial has shown that baxdrostat significantly lowers blood pressure in people whose levels remain dangerously high despite taking multiple existing medicines. The study found that nearly 4 in 10 patients achieved healthy blood pressure levels, compared to fewer than 2 in 10 on placebo.
SourceUniversity College London·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateAug 30, 2025
Dr. Roxana Mehran is recognized for her exceptional contributions to cardiovascular medicine, including designing and implementing randomized clinical trials and outcomes research projects. She has also focused on personalized medicine and developed individual risk scores for bleeding and acute kidney injury.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·DateAug 29, 2025
Researchers developed AI models that can identify signs of heart failure in patients from Appalachia using low-tech electrocardiogram results. The models achieved high accuracy and could potentially provide clinicians with an edge in protecting patients' cardiac health.
SourceWest Virginia University·JournalScientific Reports·DateAug 28, 2025