The funding will support research at UCLA's David Geffen School of Medicine, College of Letters and Science, and Fielding School of Public Health. The studies aim to inform evidence-based regulation and public health priorities.
Researchers found that patients with clonal hematopoiesis of indeterminate potential (CHIP) had a significantly higher incidence of heart failure and ischemic cardiovascular disease after cancer treatment. CHIP, a condition characterized by age-related variants in blood stem cells, puts patients at increased risk for heart complications.
The Global Centre for Asian Women’s Health has partnered with NUS Medicine to host the Women’s Health Impact Tracking (WHIT) platform, which measures progress on closing the women’s health gap across a set of conditions and countries. The platform provides clear, comparative insights to support decision-making and inform policies.
A new Scripps Research study found an association between sleep variability and the risk of developing sleep apnea and high blood pressure. Participants who slept in varying patterns had more than twice the risk of sleep apnea and were 71% more likely to have high blood pressure.
A large study found that women who underwent bypass surgery had a lower risk of major cardiovascular events and mortality compared to those who received stenting. However, women who underwent stenting had a slightly lower stroke risk.
A new study found that choosing ARB drugs from the start can lead to better adherence and improved cardiovascular health. The study, which analyzed data from 340,000 patients, showed that ARB treatment resulted in fewer side effects and higher persistence rates compared to other drug classes.
The Baveno VII consensus guidelines have reshaped portal hypertension management, focusing on early intervention and noninvasive diagnostics. Nonselective beta-blockers and transjugular intrahepatic portosystemic shunt (TIPS) are recommended for clinically significant portal hypertension diagnosis.
Researchers found that elevated ACE2 levels in individuals with high blood pressure or diabetes may be a protective mechanism, counteracting the risk factors for heart disease. This discovery could lead to more tailored treatments based on blood ACE2 levels.
A Finnish study found that adults who remained physically active throughout adulthood had a lower prevalence of metabolic syndrome at age 61. Increasing physical activity later in life, especially muscle-strengthening exercises, also mitigated risks.
Experts warn that nicotine-containing products, including vapes, heated tobacco, and shisha, cause cardiovascular damage regardless of delivery system. The report highlights a rapid rise in youth addiction fueled by flavours and social media marketing.
New research from the American Heart Association finds a strong association between gum disease and increased risk of heart attack, stroke, atrial fibrillation, heart failure, and cardiometabolic health conditions. The study suggests that effective prevention and treatment of gum disease could potentially decrease the burden of cardiov...
A $25M study will enroll 18,000 adults at high risk of heart disease and track their progress using smartphone fitness trackers. The trial aims to prove that increasing physical activity can prevent heart attacks and strokes.
Research from the UMBERTO Project found that adopting healthy lifestyles such as eating well, exercising regularly and maintaining a balanced weight significantly reduced cancer mortality. The study showed a strong link between traditional cardiovascular risk factors and survival in people with a history of cancer.
Researchers developed an AI model that can detect coronary microvascular dysfunction using a common electrocardiogram, outperforming previous models in diagnostic tasks. The model can accurately identify a condition often missed in emergency department visits, providing a cost-effective and non-invasive way to diagnose serious heart co...
A new American Heart Association scientific statement suggests that combination pills combining two or more medications may help adults with high blood pressure achieve optimal blood pressure goals more quickly, reduce their risk of heart attack and stroke, and improve long-term health. Currently, most people need two or more medicatio...
Researchers have discovered a small RNA molecule that plays a key role in controlling cholesterol production and the development of heart disease. The molecule, tsRNA-Glu-CTC, was found to boost SREBP2 activity, leading to higher cholesterol levels and increased risk of atherosclerosis.
A new policy paper highlights five critical areas for advancing data-driven policymaking to curb the rising burden of non-communicable diseases in Europe. The paper emphasizes the need for inclusive data collection, solid governance, and real-time policymaking to address inequalities and ensure equitable healthcare.
Researchers identified a way to suppress daily fluctuations in immune cells' activity, which may prevent tissue damage during daylight hours. A drug that targets neutrophils was found to alleviate inflammation and protect against infections.
A new study found that calcium accumulation in breast arteries and its progression on mammograms can predict future cardiovascular disease. Women with more severe calcification and those whose calcification worsened over time had a higher risk of heart-related events, such as heart attack, stroke, and death.
A new study finds that untreated obstructive sleep apnea accelerates cardiovascular aging, leading to higher mortality rates. Researchers used a long-term mouse model to demonstrate the chronic physiological stress created by sleep apnea fundamentally alters cardiovascular structure and function.
Cuffless devices, such as smartwatches and patches, have shown promise in measuring blood pressure but require standardized validation for medical decision-making. The American Heart Association has outlined key limitations and recommended further research to establish their accuracy.
A new study published in the Journal of the American Heart Association has found that women with uterine fibroids are at an elevated risk of heart disease. The research, which analyzed data from over 450,000 women, suggests that fibroids may serve as a marker for identifying women at increased cardiovascular risk.
Researchers at Penn State are developing a small, durable ventricular assist device (VAD) specifically designed for young children with heart failure. The PSU Child VAD aims to provide long-term support while waiting for a heart transplant, improving quality of life and outcomes.
A cohort study of adults aged 45 or older with RSV infection found a significant excess risk of cardiovascular events over 1 year, comparable in magnitude to influenza infection. This highlights the importance of RSV as a potential risk factor for cardiovascular morbidity and underscores the need for vaccination to mitigate this burden.
A new study published in JAMA Pediatrics suggests that early normalization of weight can protect the heart from childhood overweight. Researchers found that individuals who had normal weight in young adulthood after being overweight as children had a lower risk of heart attack compared to those who remained overweight.
A new study links rising temperatures to reduced sleep quality and length in US adults, particularly those living on the West Coast. The research estimates that by 2099, people could lose up to 24 hours of sleep each year due to heat, highlighting the potential impact of climate change on sleep health.
A large study found that people with type 1 and type 2 diabetes have a higher risk of sudden cardiac death, particularly in younger adults. The research also showed that sudden cardiac death contributes to shorter life expectancy for those with diabetes.
A recent study published in the American Journal of Preventive Cardiology found that only 13% of US adults with cardiovascular disease met optimal LDL-C management, highlighting significant gaps between guideline recommendations and clinical care. The study suggests actionable steps to improve adherence, including increased use of non-...
A new Tulane University study suggests that catheter ablation delivers major benefits for patients diagnosed with both atrial fibrillation and obstructive sleep apnea, significantly lowering the risks of heart failure and death. The study found a 40% drop in major cardiovascular events and a 70% decline in all-cause mortality.
A nationwide observational study from SWEDEHEART reveals that patients with type 1 diabetes have a significantly higher risk of stent complications compared to those without diabetes. The study emphasizes the need for adapted treatment and follow-up strategies for this patient group.
Researchers have identified a distinct type of frailty in younger people driven by cardiovascular and metabolic illnesses, leading to poor outcomes and premature death. The study calls for routine frailty assessments in all heart attack patients, regardless of age.
A new study by UC San Francisco combines genetic risk with cardiovascular disease risk factors to predict who is more likely to develop dementia. The expanded view may help those worried about dementia, as lifestyle changes and improved control of illnesses can reduce brain damage and potentially delay or prevent symptoms.
Researchers investigate how adjacent cities exacerbate each other's heat island effects. A study also highlights the need for improved hindcasting infrastructure in climate science. Additionally, a campaign monitors pinned clouds over industrial sources of heat and finds that trees are more reliable against heat stress than buildings.
A new study found that current cardiac screening tools are not optimal and fail to identify half the people who are at risk of having a heart attack. The researchers assessed the accuracy of widely used tools, including ASCVD and PREVENT calculators, and found that nearly half of patients would not have been recommended for preventive ...
Researchers identified 251 genetic variants that significantly affect circulating protein levels in Greenlanders, showing stronger genetic control over certain proteins in the Inuit population. The study uncovered 70 previously unreported associations and found links between Arctic-adapted genes and disease development.
A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack by delivering interleukin-4 directly to damaged heart tissue. The patch uses a microneedle system to promote repair and improve heart function without affecting the rest of the body.
A recent study published in JAMA Cardiology found that high blood pressure during adolescence can increase the risk of atherosclerosis in middle age. The study analyzed data from over 15,000 men and found that even mild hypertension at age 18 was associated with an increased risk of cardiovascular disease.
Researchers found that eating a Mediterranean diet with moderate portions of lean beef did not increase blood levels of trimethylamine N-oxide (TMAO), an emerging indicator of cardiovascular disease risk. This suggests that dietary quality is more important than the amount of beef eaten in relation to heart health.
SourcePenn State·JournalJournal of the American Heart Association·TypeRandomized controlled/clinical trial·DateNov 18, 2025
A large analysis found that even low-intensity smokers have a significantly higher risk of heart disease and death compared to non-smokers. Quitting smoking at a younger age is the best way to decrease this risk.
Researchers created a miniaturized replica of carotid arteries using 3D printing, mimicking the geometry and fluid dynamics of human blood vessels. The model revealed that platelet movement is crucial in blood clot formation, and high stress on blood vessels triggers significant platelet activity.
A mouse study by University of California, Riverside scientists suggests microplastic exposure may accelerate the development of atherosclerosis in males. The study found microplastics dramatically worsened plaque buildup in male mice, but not females.
A recent study found that regularizing bedtime without changing sleep duration can significantly lower blood pressure in individuals with hypertension. Participants who stuck to a consistent bedtime for two weeks experienced drops in their blood pressure, particularly during nighttime hours.
A new study finds that reducing arsenic levels in drinking water can decrease death rates from chronic diseases such as heart disease and cancer. Over a 20-year period, efforts to lower arsenic levels resulted in a 70% decrease in chemical levels, halving arsenic levels in urine among study participants.
Dental teams can identify hypertension and cardiovascular disease risk through blood pressure screenings in routine care visits. The American Heart Association's Healthy Smiles, Healthy Hearts initiative provides standard blood pressure screening and referral guides, empowering dentists to connect patients with primary care.
A new study published in the Hypertension Journal found that chronic pain in adults may increase their risk of developing high blood pressure, with depression playing a significant role. The study analyzed data from over 200,000 adults and found that widespread pain was associated with a higher risk of high blood pressure.
A new online calculator uses percentiles to help younger adults forecast their risk of a heart event over the next 30 years. The tool calculates a person's 30-year risk of developing heart disease using common health measures, such as blood pressure and cholesterol.
A new study reveals that sons born to mothers with type 1 diabetes show early signs of vascular dysfunction in their blood vessels, even before metabolic health is affected. The research suggests that this sex-specific effect could help clinicians assess risk and prevent cardiovascular disease earlier in life.
A comprehensive review identifies exosomes as critical mediators in the process of obstructive sleep apnea (OSA)-related diseases. OSA-induced intermittent hypoxia and sleep fragmentation alter exosome secretion and content, disrupting cell function and leading to various comorbidities.
A Cochrane review found that low-dose colchicine reduced heart attacks and strokes in people with a history of heart disease or stroke. The study involved nearly 23,000 participants and showed that taking colchicine could prevent about two of each heart attack and stroke among those with cardiovascular disease.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateNov 12, 2025
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
A new study found that standard medical care, including blood thinners, is the better choice for older people with irregular heart rhythms who are at high risk of stroke and bleeding. The catheter-based procedure was non-inferior to medical therapy in reducing stroke risk but caused more bleeding in higher-risk patients.
Using stress cardiac MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life for people with suspected angina. The test can help identify small vessel problems that may be causing chest pain, which are often under-recognized in women and other groups.
A new study found that adding a PCSK9 inhibitor to a high-intensity cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with ASCVD or diabetes. The study suggests long-term lowering with PCSK9 inhibitors can improve cardiovascular morbidity and mortality over time.
A recent study from Karolinska Institutet has identified a specific protein pattern in the blood that may reflect an increased risk of hereditary atherosclerosis. The research found that certain proteins, such as follistatin and cathepsin D, are significantly elevated in people with a family history of early-onset coronary heart disease.
A new study found that providing healthy, medically tailored meals and fresh produce boxes along with nutrition counseling can improve the quality of life for people with heart failure. The 90-day trial showed significant benefits compared to dietary counseling without food delivery.
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
A recent study found that adults with heart disease who took vitamin D doses tailored to their individual needs reduced their risk of another heart attack by more than half. The study also showed that supplementation appeared beneficial for preventing heart attack specifically.
A new study found that a polypill combining medications for heart failure improved heart function, symptoms, and quality of life. Adults with reduced ejection fraction heart failure who took the combined medication had fewer hospitalizations and greater medication adherence than those taking individual pills.
Researchers found that an earlier blood transfusion may reduce the risk of heart failure and irregular heartbeat in adults with heart disease. The study suggests that waiting until hemoglobin levels are low before transfusing blood may not be the best strategy for high-risk patients.
A large international study found that opening all blocked arteries with stents significantly reduces the risk of death from cardiovascular causes and future heart attacks compared to treating only the culprit artery. This study provides strong evidence for complete revascularization as a life-saving procedure.