A clinical trial has demonstrated that VES001 can restore normal levels of the protein progranulin in individuals with a gene mutation leading to frontotemporal dementia. This breakthrough treatment may prevent dementia in people at genetic risk, offering hope for a novel therapeutic approach.
A new study found a significant link between omega-3 intake and ADHD symptoms among Palestinian adolescents. Lower omega-3 consumption was associated with higher ADHD symptom scores, highlighting the importance of balanced nutrition in supporting cognitive health.
A new study found that access to wheelchairs through Medicare-listed suppliers is inconsistent and often challenging due to administrative requirements and long delivery timelines. The research highlights the need for policy changes to assist vulnerable older adults in accessing critical medical equipment.
Research from the University of Pennsylvania School of Medicine finds that general anesthesia may be a suitable option for women undergoing C-sections, offering them more control over their delivery experience. The study analyzed 30 years' worth of data and found small differences in newborn health between babies born under general ane...
A research team at CUNY and UT Austin discovered a way to control dark excitons, highly promising for quantum information and advanced photonic applications. They amplified light emission by 300,000 times, making them visible and controllable.
Researchers developed a 'humanized' model of aortic valve calcification, enabling testing of potential treatments. The breakthrough could lead to new therapies to stop or reverse calcium buildup, improving outcomes for people with heart disease.
Astronomers have confirmed the first sighting of a giant explosion on a nearby star using XMM-Newton and LOFAR telescopes. The coronal mass ejection (CME) was detected in a star with a magnetic field 300 times more powerful than our Sun, capable of stripping away the atmospheres of planets in its path.
The 'Otus' supercomputer provides a solution to pressing challenges through its massive parallel computing capacity, allowing researchers to simulate complex processes, identify patterns, and make predictions about future developments. The system also promotes sustainability with indirect free cooling and renewable energy sources.
Large language models systematically rate speakers of German dialects less favorably than those using Standard German, associating dialects with negative traits. The bias grows when dialects are explicitly mentioned, and larger models display even stronger biases.
Professor Iain Couzin has been included on the prestigious Global Highly Cited Researchers list seven times since 2018. His work combines behavioral biology, physics, computer science, and neuroscience to understand collective phenomena, earning him recognition for his contributions to the field of collective behaviour.
A study by researchers at UCLA and UC Davis found that climate change leads to more reported clashes with wildlife during droughts. The study analyzed data from the California Department of Fish and Wildlife's Wildlife Incident Reporting database and found a 2-3% increase in conflicts for every inch of decreased annual rainfall.
A recent study found that rainfall and temperature significantly impact the water volume in bromeliad tanks, which in turn affects mosquito development and species diversity. This knowledge can be useful for predicting malaria transmission risk and estimating the effects of climate change on disease outbreaks.
The Society of Nuclear Medicine and Molecular Imaging emphasizes the importance of education, training, and experience for safe and effective delivery of radiopharmaceutical therapy. Specialized expertise is needed to handle radioactive compounds and ensure patient safety.
Researchers from the University of Liège examined the capabilities of Midjourney and DALL·E to produce images from simple sentences, revealing both aesthetic feats and beginner's mistakes. The study highlights the limitations of translation between verbal and visual language.
A new study by Carnegie Mellon University's Wood Neuro Research Group uses advanced brain imaging and a digital visualization tool to better understand how pain is processed in the brain for people with sickle cell disease. The team found that patients had reduced connectivity across key brain networks linked to pain perception, partic...
Researchers demonstrate that bacteria can produce fabric and dye it in every color of the rainbow using a single vat. The approach uses bacterial cellulose as a potential alternative to petroleum-based fibers, reducing greenhouse gas emissions and environmental harm. The developed method yields vibrant colors that survive washing and h...
The second funding phase of Priority Program ViCom aims to advance new linguistic and cognitive models describing visual communication. Researchers will focus on developing theories, systematizing findings, and supporting early-career researchers, fostering international collaboration.
Researchers from George Washington University and the Meituan Group developed a system to coordinate nighttime transshipment and dynamic pricing, reducing spoilage by 20% and improving profitability. The system transformed perishable inventory from a loss driver to a source of profit and sustainability.
A recent study found that multilingual individuals experience slower biobehavioral aging compared to monolinguals. The study analyzed data from 86,149 participants across Europe and showed that multilingualism is associated with a lower risk of accelerated aging.
The study identifies biliary atresia splenic malformation syndrome (BASM) as the most prevalent syndromic form of biliary atresia, associated with polysplenia, situs inversus, and vascular anomalies. Genetic analyses highlight PKD1L1 and CFC1 pathways involved in nodal signaling and cardiac development.
Researchers at MIT have developed a nearly impermeable polymer film that could protect solar panels and infrastructure from corrosion. The film, made using a solution-phase polymerization reaction, completely repels nitrogen and other gases, outperforming existing polymers.
A new study could unlock the creation of brand new materials with promising biomedical applications, including smart drug delivery systems and targeted therapies. Researchers used a simple mathematical model to balance competing forces and predict the same arrangements across different materials.
A recent study co-led by Princeton and University of Chicago found that deaths caused by rainfall and rising sea levels are almost ten times higher than official statistics suggest in Mumbai. The research highlights the human toll of extreme urban flooding, with slum residents facing disproportionate risks, particularly children under ...
A new study by the Cluster of Excellence at the University of Konstanz and King's College London reveals that working from home can contribute to a fairer division of care work between men and women. In families with progressive views on gender roles, remote work actually helps to reduce existing inequalities in household tasks.
Researchers have mapped the full structure of bacteriophage Bas63 using cryo-EM, revealing unique decoration proteins and a rare whisker and collar structure. The detailed structural information will enable rational phage design and engineering efforts for specificity and target regions.
A recent study finds that artificial intelligence has a negligible effect on global greenhouse gas emissions. The researchers' analysis of US energy consumption and AI use across industries revealed that the energy usage from AI in the US equals the energy consumption for all of Iceland, but not noticeable on a global scale.
Researchers have developed a dynamic display technology that dissipates heat instead of generating it when the color changes, cooling the surface underneath. The passive cooling mechanism can be used on building billboards to show ads and help cool buildings' interiors.
Researchers identified a new subtype of T-cells that do not respond to current treatments and could impact clinical care. A genetic marker, ZBTB16, was found to be switched on in these cells, which can be used to identify them.
The Annals of the Natural History Museum Vienna is now published by Pensoft under a modern diamond open-access model. The journal publishes original research on various scientific fields, enhancing its digital transformation with Linked Open Data and OpenBiodiv Biodiversity knowledge graphs.
A new study by University of Washington researchers found that people tend to mirror AI systems' hiring biases when making decisions, even when the bias is not obvious. The study involved 528 participants who reviewed resumes and picked candidates for jobs, with some AI recommendations biased towards certain races.
Researchers have found that a one-hour plasma glucose concentration is a more sensitive marker for early detection of impaired glucose tolerance than traditional methods. This biomarker can help identify at-risk individuals and enable targeted prevention strategies.
Researchers found that lower LRIG1 expression is linked to more aggressive gliomas, a type of brain tumor. The study suggests that LRIG1 could serve as a useful marker for tumor severity and potentially as a target for future therapies.
Astronomers have observed the unique shape of a supernova explosion in unprecedented detail using ESO's VLT. The shape, resembling an olive, was revealed through spectropolarimetry, which allows for the measurement of polarisation and inference of object geometry.
Researchers explore using municipal solid waste as a low-emission, cost-effective feedstock for sustainable aviation fuel, reducing greenhouse gas emissions by 80-90%. The study suggests that adopting municipal solid waste-based jet fuels could save airlines money under carbon pricing systems.
Scientists discovered a freshwater snail's genome was duplicated, revealing the species' recent evolutionary history. This finding may hold clues to major evolutionary shifts in animals.
City of Hope experts will highlight advances in blood cancer research, cellular therapies, and precision medicine at the 2025 American Society of Hematology Annual Meeting and Exposition. The meeting will feature over 105 sessions covering topics such as CAR T cell therapy, transplant innovations, and precision medicine.
Researchers have developed a chemical compound that degrades beta-amyloid plaques, reducing symptoms of Alzheimer's disease. The compound was tested on rats and showed promising results, including reduced memory loss and improved spatial awareness.
Researchers found that a plant-based diet prevented the development of coronary microvascular dysfunction (CMD) and reversed established CMD in hypertensive rats. The diet improved function of blood vessel cells, counteracting the damaging effects of hypertension.
A recent FAU Engineering study leverages quantum computing to enhance the accuracy of chronic kidney disease (CKD) diagnosis. The research team developed and compared two automated systems: Classical Support Vector Machine (CSVM) and Quantum Support Vector Machine (QSVM). CSVM achieved remarkable 98.75% accuracy, while QSVM reached 87....
A recent US study reveals that loneliness among young adults, particularly educated females, is often accompanied by social connectedness. The research suggests that this ambivalence towards sociality may be related to significant life transitions.
JMIR Publications has integrated Signals Manuscript Checks into its publication process, utilizing AI-powered tools to streamline research integrity evaluations. This partnership aims to increase efficiency and quality, ensuring high standards of scientific integrity in published research.
Researchers analyzed 29 new and 22 previously reported cases of PCNSL involving the ventricles, finding different clinical symptoms such as headache, dizziness, and vision impairment. The study suggests that despite its unusual location, ventricular PCNSL behaves like other forms of brain lymphoma, with a recommended treatment strategy...
A Mount Sinai study found that diverse T cells and low immunosuppressive myeloid cells are key to long-term remission after CAR T cell therapy. Patients with these immune features remained cancer-free for more than five years, while others relapsed sooner.
A seven-year study reveals that marginal lands, like abandoned golf courses, can support diverse bee populations. The study found 118 confirmed species, with nearly half belonging to the globally common Halictidae family.
Researchers found that the Epstein-Barr virus (EBV) is directly responsible for triggering lupus, a chronic autoimmune condition. Most Americans carry EBV, which resides silently inside their bodies and can activate autoreactive B cells to attack healthy tissues.
A clinical trial in Africa has discovered a single-dose treatment combining sulfadoxine, pyrimethamine, artesunate, and pyronaridine (SPAP) that is as effective as traditional multi-day treatments in curing uncomplicated malaria. The study addresses the growing threat of drug-resistant malaria parasites and improves treatment adherence.
The Glenn Foundation for Medical Research is providing $2.25 million in grants to 26 postdoctoral investigators and junior faculty pursuing aging research. These programs offer critical support to early-career scientists, advancing the field of geroscience and potential therapies to extend human health.
This study provides the first nationwide map of urban gullies in the DRC, quantifying their extent, recent dynamics, and human impacts. Researchers found that gullies were formed mainly due to anthropogenic factors such as unplanned urbanization and inadequate infrastructure.
A study found that intimate physical contact reduces cortisol responses, while oxytocin administration promotes wound healing. This integration of relationship dynamics and neurohormonal modulation may lead to future interventions for improved health and recovery.
A new study found that insectivorous birds in the Eastern Himalayas are declining in survival rates and body mass due to changes in forest microclimates after selective logging. The team suggests conserving primary forests and creating shade covers or supplementing water sources to support vulnerable species.
ADCs use targeted antibodies to deliver cytotoxic payloads directly into cancer cells, destroying tumors while minimizing harm to healthy cells. Two ADCs have been approved by the FDA for gynecological cancer treatment, and numerous others are in clinical trials.
Researchers at UC Riverside and City of Hope have developed a novel Pin1 degrading compound that suppresses pancreatic cancer peritoneal metastases. The treatment targets not only cancer cells but also tumor-supporting cells, potentially overcoming treatment resistance.
Researchers have summarized recent breakthroughs in theranostic nanomaterials, engineered nanoparticles that can both diagnose and treat TBI. These materials can deliver drugs precisely where damage occurs while monitoring biological changes inside the brain.
The University of Tennessee will lead work in materials and models under a renewed $125M funding for the Quantum Science Center at Oak Ridge National Laboratory. UT's expertise in quantum spin systems will validate quantum-classical computations, while supporting students' involvement in materials science and neutron experiments.
A new real-time prediction method for September Arctic sea-ice extent has been developed using interannual increment and stepwise regression approaches. The study demonstrates high predictive performance compared to long short-term memory neural networks, with smaller prediction errors and greater stability.
A study published in The Lancet Psychiatry found that metformin can help manage weight gain in overweight or obese youth taking medication for bipolar disorder, making it a potential standard of care treatment. The MOBILITY trial showed modest but significant benefits of metformin over no treatment, with well-tolerated side effects.
A study found high rates of antibiotic-resistant bacteria in raw milk, with 95% of isolated strains resistant to penicillin and erythromycin. The presence of multidrug-resistant Staphylococcus epidermidis in raw milk highlights the urgent need for responsible antibiotic use and improved hygiene practices.
A new paper by University of Maryland School of Medicine researcher David Gorelick proposes six core competencies for medical students to know about cannabis before entering practice. The competencies address clinical utility, risks, legal landscape, and scientific evidence around medical cannabis.
Researchers from Woods Hole Oceanographic Institution and partners collected respiratory samples from 85 North Atlantic right whales using drones. The study found that the microbial matter carried valuable information about whale health, including distinct patterns linked to characteristics like robust versus thin whales.
Research from Colorado State University shows that faculty sharing internal sense of unease and inadequacy can shape students' perception of professors' overall competence, likeability, and effectiveness. Students found a hypothetical professor who publicly acknowledged feelings of being an impostor to be less hirable than an equally a...