A new injection therapy uses self-amplifying RNA to prompt the body's release of the natural heart-protective hormone ANP for several weeks. This approach aims to reduce harmful scarring, preserve healthy heart muscle and improve heart function after a heart attack.
A new study by Cleveland Clinic and Dyania Health demonstrates the potential of large language models in accurately identifying patients who could benefit from clinical research. The AI system reviewed 1,476 patients and identified 46 as potential matches, resulting in a more diverse patient population.
The Society of Interventional Radiology has published new practice guidance for treating chronic pelvic pain in women with venous-origin disorders, emphasizing interventional radiology's role in care. The guidance provides evidence-based recommendations on diagnosis, treatment options, and imaging.
Researchers found that individuals with type 2 diabetes who used GLP-1 receptor agonists in combination with healthy lifestyle habits had a substantially lower risk of major adverse cardiovascular events. Lifestyle habits that reduced cardiovascular risk included healthy eating, regular physical activity, and good stress management.
A study from the University of Copenhagen found that children with multiple tooth cavities or severe gingivitis have a significantly higher incidence of stroke, heart attack, and coronary artery disease as adults. Lifestyle factors may play an important role in this correlation.
GLP-1 weight-loss drugs may prevent further tissue damage following a heart attack, significantly reducing the risk of further life-threatening complications. Researchers found that these drugs improve blood flow to the heart by activating potassium channels, relaxing constricted blood vessels and reducing heart damage risk.
A recent study found that higher IL6 levels are associated with increased mortality, while genetically higher IL6R levels reduce all-cause mortality through cardiovascular mechanisms. The researchers suggest that IL6R antagonism may be a potential strategy for preventing cardiovascular disease.
A team of researchers from the University of Oldenburg has discovered a unique genetic pattern, or 'fingerprint', associated with NOTCH1 gene variants that commonly cause congenital heart defects. This breakthrough enables more reliable diagnoses and targeted therapies for patients and their families.
A new study found that heart attack deaths rose by 1.2% among adults under 55, particularly women who were more likely to die from a severe form of the condition. The research highlights the need for earlier risk identification and consideration of non-traditional risk factors to improve treatment.
Researchers identified multiple microRNAs linked to disease progression and built a model to distinguish high-risk patients with CKD. The M3V2 equation significantly outperformed conventional clinical markers in predicting both kidney decline and major cardiovascular events.
A new study published in Cardiovascular Research found that a single night of road traffic noise can cause stress to the heart and blood vessels, impairing blood vessel function and raising heart rate. The study also showed changes in inflammation and stress responses linked to nighttime noise exposure.
Researchers found that a bacterial metabolite regulates heart function through specific brain cells, revealing a new gut-brain-heart axis. This discovery points to potential therapies for hypertension and heart failure, and may serve as a biomarker for identifying patients at high risk.
A new study found that adding one avocado and a cup of mango to daily meals and snacks for eight weeks improved vascular function among adults with prediabetes, while also reducing diastolic blood pressure. The Avocado-Mango diet showed significant increases in flow-mediated dilation and nutrient-dense nutrients without changes in calo...
A high-fiber diet has been linked to a reduced risk of coronary artery disease in night shift workers. The study, published in the European Journal of Epidemiology, found that consuming more fiber daily can lower the risk, with moderate intake recommended for those working night shifts regularly.
A new study published in Circulation: Cardiovascular Imaging found that women with lower plaque levels in their arteries are still at risk of heart attacks. The research suggests that moderate increases in plaque burden can have a disproportionate impact on women due to their smaller coronary arteries.
A nationwide study found that adolescents and young adults with prior cervical high-grade squamous intraepithelial lesion (HSIL) are at a higher risk of cardiovascular events and mortality. The study suggests that women with prior HSIL should be more closely monitored for cardiovascular disease and prevention strategies should be imple...
The ESE and ESPE have launched a landmark Joint Clinical Practice Guidance to support structured and effective transition of young people with endocrine conditions. The Guidance provides practical, evidence-based recommendations to ensure continuity, safety and quality of care during this critical phase in a patient's life.
A new multicenter study by Kumamoto University and National Cerebral and Cardiovascular Center found that working-age adults with shorter sleep durations are more likely to develop atrial fibrillation. In contrast, retirees showed no significant association between sleep duration and AF risk.
A group of nerve cells in the brainstem has been identified as a stabilizing system for blood pressure, preventing fluctuations between daily activities. The study suggests that loss or dysfunction of these cells can lead to unstable blood pressure and is associated with conditions such as multiple system atrophy.
Researchers from Duke University found that uniform materials without complexity are the culprit behind deadly infections after heart surgery. Bioengineered grafts with decellularized tissue can greatly reduce complications. The study suggests designing new solutions similar to vascular tissue in interior complexity.
A groundbreaking study found that frail men have a significantly higher risk of dying within one year after a heart attack, challenging the prevailing narrative that high clinical risk is predominantly a female issue. The research highlights the need for sex-informed care pathways to address this disparity.
A new study reveals that C-reactive protein is associated with ventricular arrhythmias in stable coronary disease, while its relationship with heart rhythms is different in patients with cirrhosis. In cirrhosis, only high white blood cell count shows a trend for linking to unstable rhythms.
A new position statement from CSANZ and ACRA highlights telehealth as a critical tool for increasing access to quality cardiovascular care. The guidance provides best practice guidance for safe use by clinicians while emphasizing patient-centered, culturally inclusive multidisciplinary care.
The review outlines how vascular-immune crosstalk affects various diseases, revealing novel therapeutic opportunities. It highlights the shared embryonic origin of blood vessel cells and immune cells, as well as coordinated immune cell trafficking mechanisms.
A study from Lund University found that a climate-friendly diet rich in plant-based foods like wholegrains, legumes, fruit, and vegetables leads to better nutritional status compared to traditional diets. Despite lower meat consumption, most participants achieved sufficient amounts of key vitamins and minerals.
Researchers developed a new MRI technique that simultaneously displays heart tissue and blood flow, enabling precise planning for surgical repairs. This innovation provides high-quality flow images without radiation, making it essential for repeated imaging in children.
A study of 2,700 adults found that South Asian adults in the US had higher rates of prediabetes, type 2 diabetes, and high blood pressure compared to peers from other populations. This suggests the need for earlier screening and risk-factor management to prevent heart disease.
A new study finds that the quality of macronutrients matters more than their quantity for heart health, with diets rich in whole grains, fruits, and vegetables associated with a lower risk of coronary heart disease. The study also found improved cardiovascular biomarkers in healthy versions of low-carb and low-fat diets.
A comprehensive scientific review highlights pecans' positive effects on cardiovascular health, including improved lipid metabolism and antioxidant defenses. While findings on blood sugar control are mixed, the review suggests pecans may support better diet quality and satiety.
The study found that a novel subset of white blood cells becomes infected in the lung and produces type 1 interferon, which triggers cardiac damage. A modified mRNA treatment was shown to mitigate cardiac damage while preserving the immune system's protective response. The research offers great promise for developing new therapies to p...
A study by Florida Atlantic University found that ultra-processed foods (UPFs) are associated with a 47% higher risk of cardiovascular disease. Researchers analyzed data from the US National Health and Nutrition Examination Survey and found that those consuming high amounts of UPFs had a significant increase in heart attack and stroke ...
Researchers at Adelaide University have uncovered a crucial new mechanism controlling heart development by regulating key growth signals. Neural crest cells fine-tune Wnt signalling to ensure proper heart formation, and disruptions lead to serious congenital heart defects.
Ascending aortic hemiarch replacement is comparable to extended arch reconstruction for patients over 65 with acute type A aortic dissection. The study found no significant difference in long-term survival or surgical reintervention rates between the two procedures.
A late-breaking study analyzing over 2.1 million patients found that bilateral internal thoracic artery (BITA) and single internal thoracic artery plus radial artery (SITA+RA) strategies offer comparable long-term survival overall. The study suggests that patient age may play a crucial role in selecting the optimal conduit strategy.
Vinay Badhwar, MD, was elected President of The Society of Thoracic Surgeons with a three-part framework emphasizing daily practice excellence, data-driven science, and measurable impact. He aims to advance collaboration across surgical disciplines and integrate the specialty into the broader healthcare ecosystem.
Researchers analyzed cases in the STS Adult Cardiac Surgery Database to identify factors predicting postoperative risk. The study found that 16.7% of adults nationwide with CHD were considered high-risk for operative mortality and serious complications after redo cardiac surgery.
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
Researchers found that patients seen by cardiologists had lower mortality rates and fewer serious heart problems, including heart attack, sudden failure, or irregular heartbeat. The study suggests close teamwork between surgical and heart teams can improve outcomes after major surgery.
A late-breaking study at the STS Annual Meeting presents a new risk model for surgery after TAVR, showing declining operative mortality over time. The model demonstrated excellent accuracy for predicting surgical TAVR explant risk, providing valuable evidence for improving patient care and treatment strategies.
Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) significantly lowers risks of limb events, cardiovascular events, all-cause mortality, and kidney disease progression compared to dipeptidyl peptidase-4 inhibitors in patients with diabetes. GLP-1 RAs are preferred for secondary prevention in this high-risk population.
Researchers have developed a non-invasive method to estimate blood oxygen levels in heart failure patients using standard cardiac MRI. This breakthrough could spare thousands from undergoing risky tube procedures, allowing for safer and more frequent monitoring.
Middle-aged and older adults who were more active in the evenings had poorer cardiovascular health compared to their peers who were more active during the day. This study, published in the Journal of the American Heart Association, found that evening chronotypes are associated with behaviors that can affect cardiovascular health, such ...
A recent study from Penn State College of Medicine researchers found that helper T cells, typically involved in fighting infections, become overly activated in failing human hearts, causing damage. The activation of these T cells highlights the impact of inflammation and immune dysfunction in heart failure.
Researchers have uncovered a new understanding of how cardiac events are interconnected with the brain and nervous/immune systems. They found that sensory neurons in the vagus nerve detect injury and transfer signals to dedicated brain structures, leading to activation of the immune system.
A quarter of pregnant patients suffering stroke symptoms were misdiagnosed due to overlooked warning signs, according to a new study. The researchers highlight the need for better clinician education and decision-support tools to improve maternal health outcomes.
Two studies found that minor adjustments in sodium content could produce significant public health benefits without requiring individual behavior change. The research suggests reducing salt in packaged and prepared foods could prevent cases of cardiovascular disease, stroke, and deaths.
Research links long-term exposure to wildfire smoke with increased risk of stroke in US adults, estimating around 17,000 annual cases. The study suggests wildfire smoke may be more harmful than pollution from other sources, and highlights the need for preventative measures.
Smartwatches with PPG and ECG functionality improve atrial fibrillation detection, detecting it four times more often than standard care. Researchers detected heart arrhythmia in 21 patients using smartwatches compared to five in those receiving standard care after six months of monitoring.
Researchers developed a new imaging technology called fast-RSOM that captures detailed images of the smallest blood vessels directly through the skin. This technology can detect early signs of cardiovascular risk, enabling doctors to intervene sooner and guide personalized therapies.
A multi-institutional study found that living in urban areas with visible trees is associated with a lower incidence of cardiovascular disease, with a 4% decrease. In contrast, higher percentages of visible grass were linked to a 6% increase in cardiovascular diseases.
Researchers developed an AI model called DiaCardia that accurately identifies individuals with prediabetes using only ECG data. The model achieves impressive accuracy and generalizability, even in single-lead ECG data, opening possibilities for home-based screening.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
A statewide partnership in Michigan led to a significant increase in patients receiving follow-up imaging after aortic aneurysm repair. This resulted in a reduced likelihood of dying within one year of surgery and improved detection of early problems that can lead to device failure or future complications.
Researchers developed a highly sensitive blood test that can detect initial thrombin generation, a key trigger in blood clot formation. The test distinguishes between pathway-specific clotting abnormalities and suggests personalized treatment strategies, potentially predicting clinical outcomes.
A new study from the ECHO Program found that exposure to fine particulate matter (PM2.5) and nitrogen dioxide (NO2) before and after birth may influence childhood blood pressure patterns. High blood pressure in children is a growing concern worldwide, with nearly 80% increase over two decades.
Research highlights racial-ethnic differences in pregnancy-related high blood pressure risk, with Pacific Islanders and Filipinos more likely to develop a hypertensive disorder. Early identification and treatment can help prevent serious complications for both pregnant individuals and their infants.
Researchers identified bradycardia as a symptom of xylazine-opioid overdose, particularly in the Northeast, where xylazine is more prevalent. This finding may aid emergency medicine physicians in detecting xylazine exposure and providing harm reduction counseling.
Abhishek Mishra receives a prestigious $160,000 postdoctoral fellowship from the American Heart Association to explore the molecular mechanisms of heart failure with preserved ejection fraction. The funding will support Dr. Mishra's research on PTP1B inhibition as a potential therapeutic strategy for cardiometabolic diseases.
A new study in Circulation: Population Health and Outcomes journal found that TV characters were more likely to receive CPR than real-life counterparts. This discrepancy highlights the need for accurate depictions of hands-only CPR on television.
A new study from Karolinska Institutet reveals that long-term type 2 diabetes can cause red blood cells to become directly harmful to blood vessels. The researchers found that microRNA-210 plays a crucial role in this process, and its levels in red blood cells may serve as a biomarker for early detection of cardiovascular complications.