Researchers develop a novel approach to precisely encapsulate individual probiotics into microgels, enhancing survival and targeted delivery in the gastrointestinal system. The study demonstrates improved therapeutic efficacy in treating IBD using this technology.
A team of geoscientists has identified a massive underground reservoir of freshwater beneath the Great Salt Lake, extending thousands of feet below the playa. The aquifer is believed to contain water dating back to the Ice Age, which could provide a new source for restoring lakebed crusts and reducing dust storms.
Researchers used CRISPR/Cas9 to create rice mutants with increased oleic acid content and decreased linoleic acid levels. The study demonstrates a novel strategy for designing functional rice cultivars with improved nutritional value and stable agronomic traits.
The SUSA project is driving digital transformation in European healthcare education by delivering 20 bachelor's and 26 master's programs with advanced digital health competencies. This pan-European effort aims to graduate 6558 students and upskill 660 professionals, fostering interoperability and attracting top talent.
New research suggests Virtual Reality (VR) may support personal self-disclosure by offering anonymity through avatars and calming virtual environments. Nature-based VR settings proved particularly comfortable and suitable for therapeutic conversation.
A new study uses large language models and network analysis to quantify investor emotions' fragility. High emotional vulnerability is linked to unstable stock prices and lower returns.
Researchers at Kumamoto University have successfully grown a bulk inorganic crystal from water that emits circularly polarized light. This breakthrough material has the potential to revolutionize security printing, advanced displays, and photonic technologies with simple inorganic chemistry.
Researchers developed Zr-IR825 nanoparticles by combining IR825 with biocompatible metal zirconium, improving water solubility and stability. The material exhibited outstanding photothermal conversion capabilities under near-infrared light, effectively killing tumor cells while showing low toxicity to normal cells.
Researchers developed PDJA, a novel AI-based attack framework that amplifies vulnerability and bypasses defenses in multi-agent reinforcement learning systems. The approach improves attack effectiveness and cross-layer vulnerability exploitation, opening new opportunities for evaluating the robustness of AI-driven autonomous systems.
A study by Iowa State University researchers found that anthropomorphizing language, such as using mental verbs like 'think' or 'know', is less common in news writing than expected. When used, these words often describe what AI requires to function, rather than attributing human-like qualities to the system. The research team identifie...
A new method uses tiny crystals of zircon to study the past evolution of Australian landscapes, offering insights into how the environment responds to geological processes and climate change. The approach provides valuable information on the storage and reworking of sediments near the surface over millions of years.
Researchers at Nagoya University found that about half of wood mice take time to examine nuts before selecting, potentially increasing their exposure to predators. Despite this risk, the extra time investment pays off as picky eaters are more likely to select undamaged chestnuts.
The guide, based on scientific documents, provides accessible language for parents and coaches to recognize concussions in young athletes. Early recognition and removal from sport are correlated with quicker returns to competition, emphasizing the importance of 'recognize and remove'.
A recent Buck Institute study revealed that spaceflight accelerates aging due to changes in immune cell composition and epigenetic markers. However, researchers also found evidence of intrinsic rejuvenation factors that can counteract these age-accelerating stressors.
A machine learning model has identified the most important drivers of cancer survival in nearly all countries, highlighting factors such as national wealth, access to radiotherapy and universal health coverage. The model provides data-driven roadmaps for policymakers to prioritize resources and close survival gaps.
The study found that medical tourism postoperative complications may cost the NHS up to £20,000 per patient. The analysis of existing data revealed that patients who underwent surgery abroad were more likely to experience moderate to severe complications, with treatment costs ranging from £1058 to £19,549.
Moderate-intensity physical activity for an extra five minutes a day can reduce all deaths by 10% in most adults, while reducing sedentary time by 30 minutes per day can lead to a 7% reduction in deaths.
A new study published in BMC Medicine found that higher maternal blood pressure increases the risk of preterm delivery, smaller babies, and gestational diabetes. The research used Mendelian randomization to assess the link between maternal blood pressure and 24 adverse pregnancy outcomes, revealing clear causal effects.
A new study reveals that young people are at risk of engaging in serious online offenses through gradual progression from low-risk behaviors like digital piracy. Researchers found that nearly half reported engaging in illegal online behavior early on, with many describing a pattern of repeat offending.
Smartphone apps based on psychological theories are 3 times more effective than minimal support in helping people quit smoking long-term. The apps improve sustained abstinence rates when combined with traditional interventions or pharmacotherapy.
The prevalence of overweight and obesity in Africa has surged, with a significant increase in obesity over the past two decades. Women are nearly five times more likely to be obese than men, while those with tertiary-level education are three times more likely. The study's findings highlight the need for targeted public health interven...
A new study from the University of Hawaii at Mānoa challenges a 50-year-old narrative about Native Hawaiian birds, finding no evidence they were hunted to extinction. Instead, the authors suggest climate change, invasive species, and land-use changes led to the disappearances.
Combining enzymes with biochar breaks down pollutants into less harmful compounds, improving efficiency and durability. Biochar-immobilized enzymes have demonstrated impressive results in water treatment and soil remediation.
A phase 1/2 trial investigating autologous T cell therapy targeting multiple tumor antigens showed promising results in patients with advanced and surgically resectable disease. Patients responded well to the therapy, with high disease control rates and low adverse side effects.
Researchers found that biochar can soften the impacts of swings between wet and dry conditions on soil organic carbon breakdown. The study showed that stronger moisture variability speeds up decomposition and boosts microbial activity, but biochar addition helped stabilize the soil system under variable moisture conditions.
Researchers analyzed faecal samples from 82 captive and 16 wild marsupials, revealing new microbial species and antimicrobial resistance. The study found that host family, location, and diet contributed to variance between different microbiomes.
Engineered biochar shows promise in boosting crop yields, suppressing soil-borne diseases, and remediating contaminated land. Purpose-specific design is essential for optimal performance.
A study found that a small, implanted vagus nerve stimulation device produced substantial and sustained improvements in depressive symptoms, quality of life, and daily function in patients with treatment-resistant depression. The device showed lasting benefits even after two years, with nearly one-third of participants who didn't respo...
Researchers developed a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations, allowing people to protect their feathered friends. The system is based on climate patterns, tree cone production, and avian migrations.
A new study from the University of Notre Dame found that satellite-derived forest maps often disagree, creating uncertainty for conservation, climate, and development policies. The discrepancies can be as high as a factor of 10, affecting millions of hectares and human lives.
A study funded by the National Cancer Institute aims to test a low-cost intervention using future-focused thoughts to help people quit smoking. The project will examine the effectiveness of episodic future thinking in reducing impulsivity and promoting healthier choices.
Dr. Timothy Riddell has been appointed as the new executive vice president and chief operating officer of Ochsner Health, with a focus on guiding the system's long-term goals for sustainability and success. He brings 28 years of experience within the Ochsner group practice to his new role.
The journal is seeking early-career scientists to serve on its editorial team, providing hands-on experience and mentorship. Selected members will play an active role in shaping the journal's scientific vision and community engagement.
Dr. Kelley's discovery of the Lost City Hydrothermal Field revolutionized scientific understanding of fluid–rock interactions and chemosynthetic ecosystems. Her work has also transformed ocean observation through the NSF's Ocean Observatories Initiative Regional Cabled Array.
Researchers discovered chemosynthetic microbial communities formed wrinkle structures in ancient turbidites, which should not have existed in the deep-water setting. The team analyzed geologic evidence and determined that the sediment layers were indeed turbidites with biotic textures.
Pennington Biomedical researchers investigated competing body weight regulation models, analyzing the interaction of energy intake and expenditure. The study highlights the need to test state-of-the-art technology and could help explain why losing weight is challenging for some individuals.
Zhongping Lee received the 2026 Nils Gunnar Jerlov Medal for his transformative contributions to understanding light interaction with the ocean. His work reshaped ocean color science, enabling robust global observations of ocean transparency and productivity from satellites.
Researchers developed ZENN, an AI framework that recognizes and adapts to hidden differences in data quality. By using thermodynamic principles, the model distinguishes meaningful signals from uncertainty and noise.
Marine darkwaves are short-term episodes of underwater darkness that can severely impact kelp forests, seagrass beds, and other light-dependent marine life. The researchers developed a framework to compare these events across the globe, finding between 25-80 marine darkwaves along the East Cape since 2002.
The American Physical Society's Global Physics Summit will convene over 14,000 physicists worldwide for groundbreaking research presentations. The event will feature both in-person and online experiences, including scientific sessions, exhibits, and networking events.
Large language models (LLMs) provide treatment recommendations for early-stage hepatocellular carcinoma (HCC) that align with clinical guidelines. However, their performance is limited in late-stage disease, where they prioritize tumor factors over liver function. LLMs should be used as a supplement to clinical expertise.
The American College of Chest Physicians released a new clinical guideline on biologic management in severe asthma. The guideline provides evidence-based recommendations for selecting biologics for different patient populations, considering factors such as baseline oral corticosteroid use and comorbid conditions.
Researchers found that targeting lipid metabolism in tumors can lead to ferroptosis, a type of cell death dependent on fat molecules. This could pave the way for new cancer treatments that target specific mechanisms responsible for lipid processing by tumors.
Researchers found two genes, mask and clu, that regulate dopamine levels in the brain and influence behavior. Silencing these genes changed sleep patterns and response to caffeine in fruit flies, providing insights into potential treatments for neurological disorders.
In a new study, terrestrial bacteria-infecting viruses were able to infect their E. coli hosts in near-weightless conditions aboard the ISS, but with distinct mutations. The dynamics of virus-bacteria interactions differed from those observed on Earth, highlighting potential insights into microbial adaptation and human health.
A deep learning model trained on stage II colorectal cancer whole slide images accurately identified features linked to recurrence risk. The study found the model surpassed clinical prognostic parameters in predicting patient outcomes.
A Phase I study led by Timothy Yap demonstrates the potential of linavonkibart to target and prevent activation of transforming growth factor-beta 1 (TGFβ1), overcoming treatment resistance in multiple cancers. The trial showed manageable safety profiles and objective responses in heavily pre-treated patients, suggesting a promising ne...
A recent SFU study analyzed 3,200 Strava posts from Metro Vancouver runners between 2010 and 2021 to understand what makes running enjoyable. The research identified six key factors shaping runner experiences: psychological aspects, social connections, weather, surroundings, physical sensations, and path conditions.
Researchers analyzed the genome of over 100 koalas and found that two retroviruses are causing cancer deaths. They also discovered that some Koala Retrovirus (KoRV) integrations may be beneficial to koala health, increasing longevity or reproductive output.
Key imidazolyl groups induce phenylalanine flipping, significantly enhancing the cellular potency of BRD9 inhibitors for treating acute myeloid leukemia (AML). The compounds demonstrated potent binding affinity and anti-tumor efficacy in the MV4-11 xenograft mouse model.
Researchers develop a new fabrication approach to produce multi-element optical components for super-resolution imaging, enabling customized imaging systems. The technique uses consumer-grade 3D printers and low-cost materials, producing high-performance lenses at a cost of less than $1 each.
Research reveals molecular interaction between environmental and genetic risk factors triggers MS. EBV and gene variants HLA-DR15 haplotype play key roles in disease onset.
A new consensus statement provides evidence-based guidance for screening, diagnosis, treatment, and return-to-play protocols for female athletes. The updated report includes a first-of-its-kind adolescent model of the Female Athlete Triad, addressing energy deficiency in growing adolescents.
A multidisciplinary team of world-leading experts is developing an off-the-shelf engineered product that could address liver failure in millions of patients. The ImPLANT project aims to create synthetic biology-based gene circuits in human induced pluripotent stem cells to drive cell differentiation into all required liver cell types.
Women with a genetic predisposition to higher body mass index are at increased risk of all-cause mortality after breast cancer diagnosis. Targeted lifestyle recommendations can mitigate this risk.
A new hybrid wireless access network called PHWAN has been proposed to improve the performance of smart factories. The framework combines different wireless systems, including 5G, Wi-Fi, and low-power industrial networks, to adapt dynamically to the needs of different machines.
Research reveals that fat located near the colon contains an unusually high number of inflammatory fat cells and immune cells, suggesting a unique function in communicating with the immune system in the gut region. This tissue may be an adaptation to the gut microbiome and could contribute to amplifying or sustaining inflammation.
A new study reveals that resilient nematodes can persist in the Atacama Desert's hostile soil, with population diversity correlating to water profile and temperature fluctuations. The findings suggest that biodiversity in arid regions may be higher than previously assumed, but also warn of ecosystem damage.
A study finds that genome regulatory elements are conserved across echinoderms and other animal groups, controlling fundamental developmental programmes. This discovery expands our understanding of gene regulation and evolutionary novelties in vertebrates.
The new program combines limb preservation, amputation care, and reconstructive solutions like osseointegration to improve identity, functional outcome, and quality of life for patients. Patients will receive coordinated, personalized, and expert care that supports their recovery and promotes sustained overall health.
Researchers develop a framework that mirrors human expert assessment to verify AI-generated answers, filtering out clear mistakes and identifying nuanced gaps. The system saves thousands of working hours and highlights the importance of contextual knowledge and internal documentation.
This issue features revolutionary research in drug design, artificial intelligence for radiopharmaceuticals, hiPSC-derived liver organoids, and precision malignancy therapy. Groundbreaking studies showcase the potential of graph neural networks, AI-driven advancements, and innovative treatments.
Researchers developed probiotic living microneedles that penetrate biofilms, reducing pathogenic burden via photothermal killing and NIR-promoted antibiotic release. In vitro and in vivo studies show >99.9% bactericidal efficiency and 93.9% wound closure rates.
Researchers have discovered a novel drug candidate that can reverse metabolic liver disease and fibrosis, addressing a critical gap in treatment options. The compound, EVT0185, has been shown to control blood sugar levels, reduce cholesterol, and destroy fat build-up that causes liver fibrosis.
A KAIST research team developed a new analysis method to detect electronic traps in semiconductors with high sensitivity. The technique enables precise identification of defect sources, improving semiconductor performance and lifetime while reducing costs. The results demonstrate a 1,000x higher sensitivity than existing techniques.
Researchers have identified five classifications of youth who have died by suicide, highlighting the importance of earlier detection and interventions. These classifications will improve primary care providers' understanding of specific risk factors and warning signs, enabling targeted prevention efforts.
Researchers at the University of Groningen developed an atomistic model that predicts the driving force for microstructural twinning in shape memory alloys. This discovery can lead to the creation of new crystalline materials with improved reversible deformations, vibration damping, and impact absorption.
The University of North Florida has been recognized for its sustained commitment to community partnership, earning the Carnegie Elective Classification for Community Engagement for the third time. This distinction reflects years of intentional work to integrate community engagement into teaching, learning, research and service.
Researchers from the UJI Optics Group have developed a new method to correct image aberrations in single-pixel microscopy using a deformable lens. This approach combines an adaptive lens with a sensor-less method that evaluates image sharpness directly from the data, producing sharper images close to the physical resolution limit witho...
Researchers created a gear mechanism that relies on fluids to generate rotation, offering potential for new mechanical devices with improved flexibility and durability. The invention holds promise by eliminating the need for interlocking teeth and allowing for controlled rotation speed and direction.
A study by Binghamton University reveals that most renters in the US are unable to access energy efficiency improvements, leading to higher heating costs and poorer health. The 'split incentive' issue, where landlords prioritize profits over upgrades, is a major barrier to change.
A study by Johns Hopkins Bloomberg School of Public Health found that people with medical debt are more likely to experience housing instability. The research analyzed data from 1,515 US adults and found that those with medical debt had a higher risk of reporting housing instability in subsequent years.
Researchers developed a method using synthetic aperture radar images to automatically detect building destruction in conflict zones without relying on expensive data. The approach successfully reconstructed spatial patterns and timing of destruction in case studies of Beirut port explosion and Mariupol
A new study suggests that current climate actions may not effectively curb global warming acceleration, as aerosol reduction weakens cooling effect. Climate policy assessments need to consider additional climate effects from co-reduced aerosols and their risks.
A Rutgers University study finds that state-level minimum wage increases are associated with lower rates of maternal hypertensive disorders, a leading cause of maternal mortality. The research found a $1 increase in the minimum wage to be linked to 64 fewer cases per 100,000 women over five years.
A team of researchers developed an AI algorithm capable of classifying complex topological phases of matter without relying on traditional mathematical tools. The breakthrough tackles the notoriously difficult realm of non-Hermitian systems and suggests that AI can surpass human capabilities in certain domains of abstract reasoning.
Researchers used single-cell technology to analyze three brain regions of patients with sporadic early onset Alzheimer's disease. They found genes within the entorhinal cortex and hippocampus have severe disruptions consistent with symptomatic involvement in the disease.
A new study from Karolinska Institutet reveals the Epstein-Barr virus can damage the brain and contribute to multiple sclerosis through molecular mimicry. The researchers found that cross-reactive T cells are significantly more common in people with MS, and targeting these cells may lead to new treatments.
Scientists have provided a groundbreaking, physical explanation for how a magnetic field slows the movement of carbon atoms through iron in steel alloys. This discovery has the potential to improve material processing and reduce energy costs by allowing engineers to better control heat treatment, while also lowering CO2 emissions.
New research shows that vulnerable populations in the US are exposed to a larger number and higher intensity of environmental burdens. The study found strong relationships between concentrated environmental burdens and vulnerable communities, with communities of color and those with limited English fluency facing the greatest risks.
eQTLs modulate gene expression through various molecular mechanisms, providing insights into disease etiology. eQTL analysis has elucidated the functional relationship between genetic variants and complex traits in diseases such as RA, T2D, breast cancer, and SZ.
A study by Bielefeld University used anonymized WhatsApp metadata to show that personalized feedback can help people understand their communication habits. Many participants adjusted their views on response speed and chat participation after seeing data-based visualizations.
Research highlights overlooked social mechanisms connecting oral health, eating and speaking difficulties, and cognitive decline. A six-year longitudinal study found poor oral health is a strong predictor of weight loss in older adults.
Cyanobacteria can absorb and break down guanidine, using it as their sole nitrogen source, according to a new study. The ability to utilize guanidine is an advantage for colonization, despite its previous classification as a toxic substance.
A team of researchers from Keio University has developed a novel system that uses Gaussian process regression to model and reproduce complex human motions. This enables robots to adapt to touch and interact with objects in dynamic environments, improving their dexterity and versatility.
A novel 18F-labeled reversible-binding radioligand, [18F]MAGL-2011, was developed for imaging monoacylglycerol lipase with positron emission tomography. The compound demonstrated favorable brain uptake and excellent in vivo binding specificity.
Researchers discovered that protein intelectin-2 has broad-spectrum antimicrobial activity against bacteria in the GI tract. It strengthens the mucus barrier and can directly neutralize or restrain bacteria, making it a potential therapeutic agent.
MIT Energy Initiative researchers developed the largest combined dataset on global ammonia supply chains, examining economic and environmental impact of different scenarios. The study found that a full transition to clean ammonia production could cut greenhouse gas emissions by nearly 71% for a 23.2% cost increase.
A joint study by Tel Aviv University and the University of Haifa discovered that a soft coral's tentacles drive rhythmic movements through a decentralized neural pacemaker system. The system enables each tentacle to perform independent movement while achieving precise collective synchronization.
A landmark study finds that structural brain changes tied to memory decline are nonlinear, stronger in older adults, and not solely driven by known Alzheimer's-associated genes. The study suggests that cognitive decline reflects a broad biological vulnerability in brain structure that accumulates over decades.
A novel photodynamic platform combines antibacterial action, hemostasis and pain relief under natural sunlight, enabling painless, antibiotic-free therapy for infected diabetic wounds. The treatment demonstrates rapid hemostatic capability and a pronounced analgesic effect.
A new hypothesis article proposes that HPV E6 and SARS-CoV-2 spike proteins could cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53. Laboratory studies suggest that combined viral pressures on tumor-suppressor pathways may contribute to cancer progression.
The study, which reviewed over 10,000 abstracts from ten international databases, found no statistically significant link between economic inequality and well-being or mental health. The researchers suggest that policies focusing solely on reducing economic inequality may not be effective in improving population mental health.
Researchers discovered peptidomimetic inhibitors that target the hydrophobic grooves on the surface of the CBP KIX domain, disrupting CREB/CBP interactions. These stapled sulfonyl-γ-AAp peptide derivatives exhibit effective antiproliferative activity in cell-based assays and inhibit tumor growth in vivo.
Researchers discovered the cerebellum's key role in regulating the brain's reward system in people with schizophrenia. Stronger cerebellar regulation is associated with reduced negative symptoms, while weaker regulation increases symptoms. This finding opens up new avenues for targeted therapeutic interventions.
A study in mice confirms the presence of two molecules that enable precise connection between inhibitory interneurons and target excitatory neurons. This link regulates information processing and maintains balance in brain circuits, with implications for understanding neuronal disorders such as schizophrenia and autism.
A new study published in the INFORMS Journal Management Science reveals that combining unisex and gender-specific restrooms can slash wait times and promote true inclusivity. By acknowledging diverse user needs, this approach promotes efficiency and inclusivity simultaneously.
Researchers have developed a new approach to targeting hematological malignancies using degradation tail-driven CELMoD–antibody conjugates. These conjugates, such as Dara-VA-I034, demonstrate potent antiproliferative effects and complete tumor eradication at low doses.
Scientists discovered a novel method to identify upper-layer ozone intrusion events, which substantially elevate surface ozone levels and intensify atmospheric oxidation capacity. ULOI events accelerate wintertime sulfate and secondary organic aerosol formation in the North China Plain.
A new foot-and-mouth disease vaccine developed by Diamond Light Source is projected to deliver over $1.3 billion in annual benefits, transforming global livestock resilience. The vaccine's unique features, including heat stability and scalability, make it a game-changer for farmers worldwide.
Researchers developed a method to encapsulate nanodroplets of thyme extract, enabling small doses and avoiding evaporation. The technique demonstrates accurate thyme extract nanodosing is possible and can be extended to other aqueous extracts.
A new method harnesses differences in surface tension to efficiently transport liquids off microscopic surfaces, enabling efficient production of micro- and nanomaterials without damaging them. The technique uses a contact-free approach to steer fluid currents in the desired direction.
Physicists from the University of Illinois discovered a unique phenomenon where chiral materials respond to light by amplifying certain frequencies. The study sheds light on how interplay between symmetry and magnetism can lead to extraordinary effects in everyday systems.
Researchers identify a concrete biological mechanism that triggers MS, focusing on B cells and Epstein-Barr virus. This understanding may help guide future strategies to prevent or treat MS.
Researchers developed exosomes targeting myofibroblasts loaded with siFKBP10, which silenced FKBP10 gene expression, inhibiting fibroblast activation and extracellular matrix deposition. This study demonstrates a promising therapeutic strategy for idiopathic pulmonary fibrosis (IPF) treatment.
A new study by Concordia researchers explores how anxiety-inducing headlines fuel 'maternal responsibilization,' where mothers are expected to pick up the slack on addressing complex issues like climate change and social injustice. The research highlights the pressures of motherhood, including generational expectations to raise childre...
New study reveals how circular economy startups create new opportunities by reducing their environmental impact, engaging in experimentation and feedback-driven development. The research highlights three key practices that reshape markets and influence the competitive landscape for larger players.
Researchers developed an injectable hydrogel delivery system to co-deliver oncolytic adenovirus and melphalan for treating retinoblastoma. The treatment effectively controlled tumor growth, prevented brain metastasis, and preserved retinal structure and function.
PLOS has partnered with Charlesworth to expand access to publishing services for Chinese researchers and institutions, reinforcing its commitment to supporting open science globally. The partnership will enable PLOS to strengthen its presence in China through localized sales representation and innovative tools.
A new study finds that multinational firms approach patent litigation as part of a coordinated global strategy, concentrating lawsuits in jurisdictions with similar legal outcomes. When outcomes diverge, firms diversify their litigation locations to manage uncertainty and risk.
A new strategy for parallel adaptive Cartesian grid generation is introduced, combining features of generated grid cells and estimating iterations needed. This approach significantly speeds up grid generation using the same number of cores, improving computational efficiency and scalability.
A new study by ESMT Berlin shows that entrepreneurs can increase support from the silent majority by broadening their public replies to vocal commenters. By managing conversational pathways, founders can create multiple entry points without fragmenting the main story.
A novel parameterization method for orbits near collinear libration points has been developed, allowing for systematic cataloging and robust identification of cislunar objects. The method enables the characterization of motion along two directions, providing critical insight into spacecraft maneuvers and transfer events.
A study investigates dynamic changes in cardiac function and mitochondrial damage in a mouse model of cirrhotic cardiomyopathy. Key findings include progressive cardiac dysfunction, inflammation, and mitochondrial injury contributing to disease progression.
A new study examines behavioral mechanisms of rural distributed photovoltaic development, finding that collaboration between PV enterprises and village organizations is key to expanding adoption. The research also highlights the importance of balancing self-consumption requirements with grid capacity constraints.
A comprehensive genomic characterisation of E. coli strains isolated from diabetic foot ulcers reveals high diversity and antibiotic resistance. The study provides valuable insights into the specific pathogens involved in diabetic foot disease and suggests potential targets for improved treatment strategies.
A nationwide study found that depression frequently precedes the diagnosis of Parkinson's disease and Lewy body dementia. The risk of depression rises steadily in the years leading up to diagnosis, peaking before diagnosis, and remains elevated for several years afterward.
Aspiring nature writers will participate in a unique workshop and ecotour in the remote Smith Inlet, led by Lesley Evans Ogden. The program offers daily writing coaching and feedback sessions, with optional one-on-one coaching, and includes accommodations, meals, and wildlife tours.
A new approach to treating KRAS-mutated lung adenocarcinomas has been identified, using a combination of ERBB inhibitors and Aurora kinase inhibitors. This therapy shows significant effectiveness against existing treatments, offering hope for patients with limited options.
The FXYD family proteins have diverse physiological and pathological roles, influencing ion transport in different organs and tissues. Altered expression or dysfunction of these proteins is associated with numerous diseases, including cardiovascular, neurological, renal, and cancer disorders.
A study found that the rate of opioid use disorder medication use among surgical patients increased significantly between 2016 and 2022. The majority of users were taking buprenorphine, which has advantages in safety and pain control compared to other options.
A landmark study identifies 11 lipid-related metabolites that are causally associated with major depressive disorder (MDD), including 8 protective effects. The research reveals shared genetic signals between lipid metabolites and MDD, clustering in key genomic regions involved in fatty acid metabolism.
Researchers create a powerful modular soft origami actuator that enables high-speed, agile movements in search and rescue applications. The Electrohydraulic Origami (EHO) actuator achieves remarkable dynamic performance, outperforming existing soft actuators.
A 12-month aerobic exercise program reduced brain age by 0.6 years, while a control group showed a slight increase. The study suggests that following current exercise guidelines may help keep the brain biologically younger in midlife, supporting clearer thinking and stronger memory.
Resonant breathing significantly reduced anxiety and insomnia symptoms and improved heart rate variability in hospitalised psychiatric patients with severe somatic symptoms. The intervention was well-tolerated and required minimal cognitive effort.
Researchers have developed a refined mouse model that mimics chronic Pseudomonas aeruginosa lung infection in old age, overcoming limitations in experimental respiratory infection research. The agar bead-based delivery strategy allows sustained observation of infection dynamics, tissue damage, and immune responses in aging lungs.
Researchers developed a novel aqueous electrolyte, MASSE, which improves AZMBs stability and reversibility at elevated temperatures. The multiphase design suppresses side reactions and promotes uniform zinc ion deposition, enabling stable battery operation in harsh thermal environments.
Scientists at Technical University of Munich create constructed soils by mixing excavated soil with compost and biochar, resulting in improved fertility and carbon accrual. These new urban soils can be tailored to specific use cases, such as protecting groundwater or enhancing plant growth in green areas.
The American Cancer Society's new 'Cancer Statistics, 2026' report reveals a historic milestone: US cancer survivorship has reached a record 70%, driven by major gains in cancers once considered difficult to treat. However, the report also highlights persistent disparities, concerning increases in cancer among women and younger adults.
Researchers identified bradycardia as a symptom of xylazine-opioid overdose, particularly in the Northeast, where xylazine is more prevalent. This finding may aid emergency medicine physicians in detecting xylazine exposure and providing harm reduction counseling.
A study of Western populations found broad public approval for supporting Ukraine to maintain its political and territorial sovereignty. Key findings include a strong endorsement of military support, rejection of Russia's positions on territorial claims, and limitations on public backing due to high casualty numbers and nuclear escalat...
Researchers developed a copper-palladium bimetallic catalyst that produces high-quality ammonia through an electrochemical nitrate reduction reaction. The catalyst's dynamic Cu-PdH x interface sites exhibit superior intrinsic activity, achieving remarkable production rates and durability.
The double swept waverider demonstrates outstanding comprehensive performance through numerical simulation verification. It maintains an ideal longitudinal static stability margin of approximately 2%, laying a solid foundation for practical engineering applications.
The Giant Magellan Telescope has appointed Daniel T. Jaffe as its new president, succeeding Robert Shelton, who announced his retirement last year. Jaffe brings decades of leadership experience in research, astronomy instrumentation, and academia to lead the observatory through its next phase of construction.
A team of researchers has developed a robust hydrogen-bond network in electrolytes to enhance the performance of aqueous zinc-ion batteries. The new design minimizes the reactivity of water molecules, suppressing deterioration on both electrodes and achieving long-lasting cycling stability with high capacity retention.
Scientists discovered that the brain sorts emotionally significant stimuli into three independent channels: salience, valence, and value. This allows the brain to evaluate information efficiently and guide decisions.
A new global modeling study introduces a differentiated carbon pricing mechanism to coordinate regional carbon prices with cost-fairness. This approach helps raise climate ambition by reducing trade and welfare imbalances, particularly for energy-intensive and trade-exposed industries.
Scientists used multiple space-based instruments to track the evolution of a solar eruption, observing how it reduced background cosmic-ray activity. This approach has potential for improving space-weather forecasting and protecting satellites, astronauts, and power grids.
Scientists successfully observed a quinoxalinyl radical forming within nanoseconds using µSR spectroscopy. The technique enabled real-time detection of highly reactive aromatic heterocyclic radicals in isocyanide insertion reactions.
A Korea University study successfully mimics heart mechanics in organoids using three-dimensional magnetic torque, enhancing cardiac differentiation, maturation, and vascularization. This breakthrough could improve drug safety testing by providing more accurate human-relevant models for cardiotoxicity screening.
Researchers challenge a decades-old dark matter theory, suggesting it could have been 'incredibly hot' when first born. The study opens up new possibilities for dark matter and its interactions with other matter, providing clues about the origins of our Universe.
Researchers introduce a new citation index called 'nu' that balances productivity and citation quality, lying between the h-index and g-index. The authors propose a more balanced assessment of research impact by considering both productivity and citation quality.
A study in mice found that paternal immune activation affects small RNAs in sperm, leading to changes in offspring phenotypes such as increased body size and impaired insulin sensitivity. The findings suggest a potential mechanism for intergenerational transmission of health disorders.
Researchers developed an open-source robotic system to automate passaging of cells in 96-well microplates, reducing manual labor by 61% and improving consistency in cell density. The system also showed improved imaging site usability and increased experimental reproducibility.
Researchers from Hanbat National University develop switchable thermochromic transparent woods for smart windows, blocking UV radiation and reducing thermal conductivity. The material enables energy-autonomous light regulation and protects skin without sacrificing visible light.
A meta-analysis of 18 studies found that playing linear number board games can meaningfully improve early math skills like counting, number recognition, and understanding quantity. Brief play sessions of 10 minutes or less have lasting benefits for young children's numeracy skills.
A new study at the University of Minnesota Twin Cities investigates how floodwaters transport and bury animal bones to understand fossil formation. The research provides clues for understanding animal extinction and environmental changes.
A new diet option has been shown to improve both physical symptoms and biological indicators of mild-to-moderate Crohn's disease. Participants in the fasting mimicking group experienced significant declines in fecal calprotectin, a protein indicating gut inflammation, and showed clinical benefits even after just one cycle.
A new study finds that electric vehicles combined with solar-powered off-grid charging systems could be viable in Africa sooner than expected. The research shows that the cost of charging accounts for a small portion of total vehicle costs, making electric scooters and motorbikes already an attractive option.
Researchers found that trees recovering twice as fast in tropical forests with sufficient nitrogen could be preventing the annual sequestration of 0.69 billion tonnes of carbon dioxide. The study suggests ways to boost carbon capture through reforestation by managing nutrients available to trees.
Cells use a complex rhythm to respond to different types of stress, such as starvation or salt stress, with insulin-driven protein DAF-16 acting as a key regulator. The research may contribute to understanding diseases like diabetes and cancer, as well as aging.
A new study reveals that tropical forests can regrow up to 95% faster when given sufficient nitrogen, allowing them to absorb more carbon dioxide. This finding suggests that targeting nitrogen pollution from farms and factories may be crucial in helping young forests recover and act as natural climate solutions.
Researchers developed a tool to measure gut inflammation levels using luminescent reporting, detecting high levels of granzyme A enzyme in inflamed gut tissue. The new technique shows promise for accurate IBD diagnosis and monitoring, reducing invasive procedures.
ACCESS-AD aims to address Alzheimer's disease challenges with a coordinated framework for diagnosis, treatment and monitoring. The project combines advanced neuroimaging with digital biomarkers to support early patient identification and personalized treatment pathways.
A new study from Nagoya University in Japan has found that petrolatum-based eye ointments can cause MicroShunt glaucoma implants to swell and potentially rupture. The study suggests that clinicians should avoid using these ointments on patients with the implant, particularly when it is exposed outside the conjunctiva.
A new study by the University of Waterloo found that consuming local waterfowl may lead to higher levels of mercury and omega-3 fatty acids in Indigenous communities. Researchers suggest including waterfowl in monitoring programs to balance nutrition and risk reduction.