Articles tagged with Cardiovascular Disorders
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Augsburg researchers identify reticulated platelets as key players in blood clot formation, providing promising therapeutic approaches. The study's findings could lead to personalized platelet inhibition and tailored therapies.
Researchers analyzed data from over 90,000 patients with heart failure and obesity to show that GLP-1 medications can significantly reduce the risk of hospitalization due to heart failure and all-cause mortality. The study found a greater than 40% reduction in these outcomes compared to a placebo group.
A Phase III clinical trial has shown that baxdrostat significantly lowers blood pressure in people whose levels remain dangerously high despite taking multiple existing medicines. The study found that nearly 4 in 10 patients achieved healthy blood pressure levels, compared to fewer than 2 in 10 on placebo.
A new study published in The New England Journal of Medicine and the European Heart Journal finds that beta blockers, commonly prescribed after a heart attack, provide no clinical benefit for patients with preserved heart function. Women treated with beta blockers had a higher risk of death, heart attack, or hospitalization for heart f...
Dr. Roxana Mehran is recognized for her exceptional contributions to cardiovascular medicine, including designing and implementing randomized clinical trials and outcomes research projects. She has also focused on personalized medicine and developed individual risk scores for bleeding and acute kidney injury.
A landmark clinical trial found that Transcendental Meditation significantly reduced diabetes risk factors and supported weight loss in older Black women at high risk for heart disease. Meditation improved blood sugar control, insulin resistance, cholesterol, and weight.
A new report from Emory University reveals that certain mental health conditions can raise the risk of developing heart disease by 50-100% and adverse outcomes from existing heart conditions by 60-170%. The study emphasizes a bidirectional relationship between cardiovascular disease and mental health, highlighting the need for an integ...
Researchers have successfully treated damage caused by heart attacks in non-human primates using gene therapy, restoring both strength and rhythm of the damaged hearts. The treatment improved heart function in pathological conditions with no adverse effects observed.
A recent study using human iPSC-heart cells found that fentanyl abuse can impair heart function, leading to rhythm defects. The research reveals changes in calcium signaling and a worsened effect when combined with stimulants like isoproterenol.
Researchers developed AI models that can identify signs of heart failure in patients from Appalachia using low-tech electrocardiogram results. The models achieved high accuracy and could potentially provide clinicians with an edge in protecting patients' cardiac health.
A new study found that automatic chest compression devices can effectively perform CPR on a floating manikin, reaching depths of up to 53mm. This finding contradicts current NASA emergency protocols and suggests space agencies may need to reconsider their guidelines for treating cardiac arrest in space.
Researchers discovered that atherosclerotic plaques contain gelatinous biofilms formed by bacteria, which can trigger inflammation and rupture of the plaque leading to myocardial infarction. The study also validated an antibody targeting these bacteria, suggesting new diagnostic and therapeutic strategies for myocardial infarction.
Dr. Valentin Fuster, a renowned cardiovascular expert, has been awarded the inaugural World Heart Federation oration lecture for his groundbreaking work in promoting global cardiovascular health. He will discuss early detection and education as key strategies for preventing heart disease, focusing on low- and middle-income countries.
New research reveals that older age and low aerobic fitness levels are strong and independent risk factors for heartbeat irregularities, or arrhythmias, in healthy adults. Regular exercise can help reduce the risk of frequent and complex atrial arrhythmias.
Late-breaking clinical trials and science at TCT 2025 will present pivotal data on novel therapies, devices, and techniques aimed at preventing and treating cardiovascular conditions. The symposium delivers high-impact findings that shape clinical practice and enhance outcomes for patients with heart and vascular disease.
The American Heart Association has extended its Rural Health Care Outcomes Accelerator program until 2028, expanding access to cardiovascular care and quality improvement resources for over 1,000 rural hospitals. This extension aims to address the significant disparities in health outcomes between urban and rural communities.
A cardiac device trial published in eClinicalMedicine found that improving enrollment of females in such trials can better guide care for all patients. One-year interim study results revealed that participants assigned male at birth were twice as likely to die or experience life-threatening heart rhythm abnormalities, while females sho...
A new guideline from the Canadian Task Force on Preventive Health Care provides a menu of effective options to help people quit smoking, including behavioural and medication options. The guideline aims to address the challenges of nicotine addiction and offers personalized choices for quitting tobacco.
A cross-sectional study found that Asian, Black, and Hispanic transgender beneficiaries have high prevalence of cardiovascular conditions. These disparities are attributed to the intersection of gender, race, and ethnicity, highlighting the need for targeted support.
A global study reveals racialized and Indigenous communities face significantly higher rates of cardiovascular disease due to data gaps. The research highlights the importance of accurate data on race and ethnicity in addressing health inequalities.
A study published in JACC Advances suggests that a regular sleep schedule can reduce the risk of clinical events in adults with heart failure. The research found that even moderately irregular sleep doubles the risk of another clinical event within six months.
Research shows that cardiovascular health scores among older adults with high blood pressure, stroke, or heart failure decreased significantly. The study analyzed data from the US National Health and Nutrition Examination Survey, finding that physical activity and blood pressure scores were low for those with cardiovascular disease.
A new study reveals that endometriosis can lead to lower blood pressure responses in women due to altered autonomic nervous system functions. This finding may have significant implications for diagnosis and treatment of the condition.
Researchers found a connection between high TMAO levels and faster rates of aneurysm expansion, as well as greater risk for needing surgery. Targeting TMAO levels may help prevent and treat aneurysmal disease beyond surgery.
A team of researchers created a 3D-bioprinted model of stenotic brain blood vessels to study the effects of abnormal flow patterns on endothelial cells. The model successfully replicated physiological conditions, including upregulation of inflammatory markers.
Researchers at NYU Langone Health discovered that restricted blood flow can accelerate breast cancer growth by aging the immune system. This effect is caused by impaired blood flow triggering a shift towards immune cell populations that cannot efficiently fight infections and cancer.
The Society for Cardiovascular Angiography & Interventions (SCAI) has published a new position statement providing best-practice guidance for the treatment of patent ductus arteriosus (PDA) in premature infants using transcatheter occlusion. The guidance emphasizes patient selection, pre-procedural planning, and post-procedure follow-u...
Researchers from the University of South Australia have identified a potential early warning system for Takotsubo syndrome in ICU patients using electrocardiogram patterns and blood markers. Critical care nurses with advanced ECG skills can play a key role in recognising early signs of the condition.
Research found Covid infection may accelerate blood vessel aging around five years, especially in women, leading to a higher risk of cardiovascular disease. The study included 2,390 participants from 16 countries and found stiffer arteries in all three groups of patients who had been infected with Covid.
Researchers at the University of Sydney have discovered a new biological pathway that may help explain why people with type 2 diabetes are more prone to developing blood clots. A protein called SEC61B was found to disrupt calcium balance inside platelets, making them more likely to form clots.
A study in mice found that high triglyceride levels directly cause abdominal aortic aneurysms, challenging the notion that they are merely biomarkers of vascular disease. Researchers identified specific proteins and lipoproteins as causal drivers of aneurysm development and growth.
High humidity exacerbates extreme heat's negative impact on cardiovascular health, increasing the risk of heart-related emergencies by six times. Researchers analyzed over 340,000 emergency room visits in Dhaka, Bangladesh, finding a significant association between high heat and humidity levels.
A study led by Lancaster University found that social and environmental factors impact a patient's physical readiness for surgery. Patients from socioeconomically deprived areas tend to have lower cardiorespiratory fitness, which can lead to poorer surgical outcomes.
A recent study has found that women who experienced stalking or obtained restraining orders are more likely to develop heart disease and stroke than those who did not. Researchers analyzed data from over 66,000 women and found a strong association between stalking and cardiovascular disease.
Researchers at the University of Graz and the University of California, San Diego have developed a novel method to determine omega positions of lipids in complex biological samples. This breakthrough enables the study of biological mechanisms in unprecedented detail, particularly for inflammation-related diseases.
Initiation of semaglutide in adults leads to reductions in weight and cardiovascular risk factors, while increasing health care expenditures. These findings suggest potential clinical benefits, highlighting the need for long-term evaluation of semaglutide's economic impact.
Researchers are exploring whether wearable devices can detect early signs of cardiovascular disease through physical activity, sleep and blood pressure data. The study aims to develop a machine-learning model that uses data from wearable sensors to predict cardiovascular risk.
A new study published in JACC found that using portable HEPA air filters at home can significantly lower systolic blood pressure in adults with elevated readings. The study found an average 2.8 mmHg reduction in SBP after one month of HEPA filtration.
Research finds CPAP lowers cardiovascular risk by 17% in patients with high-risk OSA, but may increase risk by 22% in those without high-risk OSA. The study suggests a more personalized approach to treating OSA, focusing on patients with high-risk features.
A personalized approach to recommending CPAP machines for patients with obstructive sleep apnea (OSA) may decrease adverse cardiovascular events. However, CPAP use can also increase cardiovascular risk for those with low-risk OSA markers.
A landmark study found that adopting five healthy lifestyle habits—healthy weight, no smoking, regular physical activity, high-quality diet, and moderate alcohol intake—can reduce cardiovascular disease risk by up to 86% in women with a history of gestational diabetes. Women who followed all these habits had no cardiovascular events ov...
A new study from University of California San Diego found that frequent standing breaks can lower diastolic blood pressure in postmenopausal women. Women who increased daily sit-to-stand movements saw measurable improvements in blood pressure, with an average decrease of 2.24 mmHg within three months.
A clinical trial found that participants who followed a minimally processed diet lost twice as much weight compared to those on an ultra-processed diet. The study suggests that cutting down on processing can help sustain a healthy weight long term.
Researchers highlight the importance of understanding heart-lung interactions in treating pulmonary vascular disease. Studies show that dysfunction in one organ often exacerbates problems in the other, leading to systemic effects.
A team of researchers is using NCSA resources to simulate the long-term progression of atrial fibrillation, a type of irregular heartbeat. By modeling the heart's electrical activity, they have uncovered a vicious cycle where adaptations to maintain calcium balance lead to continued arrhythmias and eventually a permanent condition.
Cambridge scientists have developed a new drug that has the potential to reduce brain damage from stroke by blocking ischaemia-reperfusion injury. The treatment, acidified disodium malonate (aDSM), was shown to decrease brain damage by as much as 60% in mice with stroke-induced brain damage.
The MISSION Act implementation led to significant decreases in travel times for eligible veterans seeking non-VA care. However, this shift was linked to a rise in major adverse cardiovascular events within 30 days of procedures like percutaneous coronary intervention and coronary artery bypass grafting.
Researchers identified a new strategy to repair damaged heart tissue by reactivating the PSAT1 gene through synthetic modified messenger RNA. The study found that mice treated with PSAT1-modRNA showed robust increases in cardiomyocyte proliferation, reduced tissue scarring, and improved heart function.
A new online tool calculates a person's 'heart age' based on cardiovascular disease risk factors, revealing significant gaps among certain groups. On average, women had a heart age of 55.4, while men had an average heart age of 56.7, with disparities found among those with lower incomes or education.
Researchers found that high rates of coronary heart disease were linked to poverty, limited healthcare provider availability, and low broadband access. However, some counties with similar challenges reported lower-than-expected cardiovascular outcomes, suggesting the need for tailored strategies to address health disparities.
A study found that prolonged sitting decreases cutaneous vasodilatory function under both constant and alternating temperature conditions. Alternating exposure to cooling and heating did not significantly suppress these changes.
Researchers developed a chemical probe that binds to damaged mitochondrial DNA, blocking enzymatic processes that lead to its degradation. This approach lessens mtDNA loss, preserving energy production in vulnerable tissues. The new molecule successfully reduced inflammation and maintained functional DNA despite chemical tagging.
A prospective cohort study found that weekend warriors and regular activity patterns reduced risks for all-cause and cardiovascular mortality among adults with diabetes, demonstrating the importance of any physical activity. The study also compared GLP-1RAs and DPP4is in dementia risk among older adults with diabetes and found no clear...
A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being. The review confirms that heart-healthy behaviors positively impact brain function, vision, hearing, muscle strength, and reduce the risk of chronic diseases.
A new study found that scar tissue in the heart of healthy male endurance athletes aged 50 or older may increase their risk of abnormal heart rhythms and sudden cardiac death. The research used magnetic resonance imaging and ECG recorders to track the participants' heart activity over two years.
A University of Cincinnati researcher is investigating how excess sugar impacts cardiovascular structure and function in people with diabetes. The study focuses on a protein called GLUT1, which becomes overactive in diabetes, leading to harmful changes at the cellular level.
A new study from the University of South Australia confirms that eggs are not high in cholesterol and do not contribute to cardiovascular disease. In contrast, saturated fat intake was found to increase LDL levels, highlighting the importance of dietary balance for heart health.
A study from Mount Sinai Hospital found that patients with heart failure and atrial fibrillation who undergo mitral edge-to-edge repair have a doubled risk of death or rehospitalization for heart failure compared to those without AF. The researchers recommend aggressive treatment of AF before the procedure to improve outcomes.
The study found a significant increase in extremely severe obesity among US children and adolescents, leading to severe metabolic and cardiovascular complications. Extremely severe obesity was linked to conditions like metabolic dysfunction-associated steatotic liver disease, prediabetes or diabetes, and metabolic syndrome.
Research suggests that childhood trauma can lead to a chain reaction of mental and physical health problems later in life. The study found that children who experienced negative events and unsafe environments in early adolescence were more likely to develop cardiovascular health issues and accelerated aging as young adults.