A new study by UC San Francisco combines genetic risk with cardiovascular disease risk factors to predict who is more likely to develop dementia. The expanded view may help those worried about dementia, as lifestyle changes and improved control of illnesses can reduce brain damage and potentially delay or prevent symptoms.
Researchers investigate how adjacent cities exacerbate each other's heat island effects. A study also highlights the need for improved hindcasting infrastructure in climate science. Additionally, a campaign monitors pinned clouds over industrial sources of heat and finds that trees are more reliable against heat stress than buildings.
A new study found that current cardiac screening tools are not optimal and fail to identify half the people who are at risk of having a heart attack. The researchers assessed the accuracy of widely used tools, including ASCVD and PREVENT calculators, and found that nearly half of patients would not have been recommended for preventive ...
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Researchers identified 251 genetic variants that significantly affect circulating protein levels in Greenlanders, showing stronger genetic control over certain proteins in the Inuit population. The study uncovered 70 previously unreported associations and found links between Arctic-adapted genes and disease development.
A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack by delivering interleukin-4 directly to damaged heart tissue. The patch uses a microneedle system to promote repair and improve heart function without affecting the rest of the body.
A recent study published in JAMA Cardiology found that high blood pressure during adolescence can increase the risk of atherosclerosis in middle age. The study analyzed data from over 15,000 men and found that even mild hypertension at age 18 was associated with an increased risk of cardiovascular disease.
Researchers created a miniaturized replica of carotid arteries using 3D printing, mimicking the geometry and fluid dynamics of human blood vessels. The model revealed that platelet movement is crucial in blood clot formation, and high stress on blood vessels triggers significant platelet activity.
A mouse study by University of California, Riverside scientists suggests microplastic exposure may accelerate the development of atherosclerosis in males. The study found microplastics dramatically worsened plaque buildup in male mice, but not females.
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Researchers found that eating a Mediterranean diet with moderate portions of lean beef did not increase blood levels of trimethylamine N-oxide (TMAO), an emerging indicator of cardiovascular disease risk. This suggests that dietary quality is more important than the amount of beef eaten in relation to heart health.
A large analysis found that even low-intensity smokers have a significantly higher risk of heart disease and death compared to non-smokers. Quitting smoking at a younger age is the best way to decrease this risk.
A new online calculator uses percentiles to help younger adults forecast their risk of a heart event over the next 30 years. The tool calculates a person's 30-year risk of developing heart disease using common health measures, such as blood pressure and cholesterol.
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A recent study found that regularizing bedtime without changing sleep duration can significantly lower blood pressure in individuals with hypertension. Participants who stuck to a consistent bedtime for two weeks experienced drops in their blood pressure, particularly during nighttime hours.
A new study finds that reducing arsenic levels in drinking water can decrease death rates from chronic diseases such as heart disease and cancer. Over a 20-year period, efforts to lower arsenic levels resulted in a 70% decrease in chemical levels, halving arsenic levels in urine among study participants.
Dental teams can identify hypertension and cardiovascular disease risk through blood pressure screenings in routine care visits. The American Heart Association's Healthy Smiles, Healthy Hearts initiative provides standard blood pressure screening and referral guides, empowering dentists to connect patients with primary care.
A new study published in the Hypertension Journal found that chronic pain in adults may increase their risk of developing high blood pressure, with depression playing a significant role. The study analyzed data from over 200,000 adults and found that widespread pain was associated with a higher risk of high blood pressure.
A Cochrane review found that low-dose colchicine reduced heart attacks and strokes in people with a history of heart disease or stroke. The study involved nearly 23,000 participants and showed that taking colchicine could prevent about two of each heart attack and stroke among those with cardiovascular disease.
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A new study reveals that sons born to mothers with type 1 diabetes show early signs of vascular dysfunction in their blood vessels, even before metabolic health is affected. The research suggests that this sex-specific effect could help clinicians assess risk and prevent cardiovascular disease earlier in life.
A comprehensive review identifies exosomes as critical mediators in the process of obstructive sleep apnea (OSA)-related diseases. OSA-induced intermittent hypoxia and sleep fragmentation alter exosome secretion and content, disrupting cell function and leading to various comorbidities.
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
A new study found that a polypill combining medications for heart failure improved heart function, symptoms, and quality of life. Adults with reduced ejection fraction heart failure who took the combined medication had fewer hospitalizations and greater medication adherence than those taking individual pills.
Researchers found that an earlier blood transfusion may reduce the risk of heart failure and irregular heartbeat in adults with heart disease. The study suggests that waiting until hemoglobin levels are low before transfusing blood may not be the best strategy for high-risk patients.
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A new study found that standard medical care, including blood thinners, is the better choice for older people with irregular heart rhythms who are at high risk of stroke and bleeding. The catheter-based procedure was non-inferior to medical therapy in reducing stroke risk but caused more bleeding in higher-risk patients.
Using stress cardiac MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life for people with suspected angina. The test can help identify small vessel problems that may be causing chest pain, which are often under-recognized in women and other groups.
A new study found that adding a PCSK9 inhibitor to a high-intensity cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with ASCVD or diabetes. The study suggests long-term lowering with PCSK9 inhibitors can improve cardiovascular morbidity and mortality over time.
A recent study from Karolinska Institutet has identified a specific protein pattern in the blood that may reflect an increased risk of hereditary atherosclerosis. The research found that certain proteins, such as follistatin and cathepsin D, are significantly elevated in people with a family history of early-onset coronary heart disease.
A new study found that providing healthy, medically tailored meals and fresh produce boxes along with nutrition counseling can improve the quality of life for people with heart failure. The 90-day trial showed significant benefits compared to dietary counseling without food delivery.
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Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
A recent study found that adults with heart disease who took vitamin D doses tailored to their individual needs reduced their risk of another heart attack by more than half. The study also showed that supplementation appeared beneficial for preventing heart attack specifically.
A large international study found that opening all blocked arteries with stents significantly reduces the risk of death from cardiovascular causes and future heart attacks compared to treating only the culprit artery. This study provides strong evidence for complete revascularization as a life-saving procedure.
Researchers found that drinking a cup of caffeinated coffee per day reduced Atrial Fibrillation (A-Fib) by 39% in patients with persistent atrial fibrillation. The study, funded by the National Institutes of Health, suggests that coffee may be protective against A-Fib and could potentially reduce blood pressure.
Researchers found olezarsen significantly reduced acute pancreatitis incidence by 85% in patients with severely elevated triglyceride levels. The drug also lowered triglyceride levels below 500mg/dL in over 85% of participants.
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A study published in JAMA finds that using different methods to estimate glomerular filtration rate (eGFR) can lead to significant discrepancies, particularly for those with chronic kidney disease. The findings suggest that cystatin C-based eGFR may be more accurate in predicting clinical outcomes.
The American College of Cardiology and OpenEvidence are collaborating to integrate AI technology into clinical workflows, enhancing patient care and outcomes. The partnership aims to translate scientific discovery into clinical implementation, providing clinicians with timely and accurate medical evidence.
A new international study confirms that drug-coated balloons can effectively treat larger narrowed blood vessels, offering a safer alternative to stents. The findings validate the method developed by Professor Bruno Scheller and demonstrate its efficacy in treating arteries with diameters larger than 2.75 mm.
A recent study from Houston Methodist reveals how Alzheimer's can disrupt the connection between nerves and blood vessels in fat tissue, worsening heart and metabolic conditions. The research highlights a potential link between neurodegeneration and cardiovascular and metabolic disorders.
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
The American Heart Association's inaugural CarePlan Challenge recognizes innovators who create digital solutions that transform preventive care, improve disease management and enhance patient engagement. The selected solutions showcase integration of the Association's science-based CarePlans and other digital tools.
MIT engineers have developed a programmable drug-delivery patch that can reduce damaged heart tissue by 50 percent and improve cardiac function. The patch is designed to release different drugs at specific times, promoting healing and regeneration of cardiac tissue.
A large-scale study published in the European Heart Journal found no increased risk of heart attack and stroke among transgender women taking hormone oestradiol. In contrast, transgender men using testosterone have a higher risk due to factors such as high blood pressure and poorer cholesterol levels.
The American Heart Association brought hypertrophic cardiomyopathy and Hands-Only CPR awareness to a historic college football game, aiming to empower young athletes and their families with critical knowledge. The organization aims to double cardiac arrest survival rates by 2030 through its Nation of Lifesavers movement.
The American Heart Association has named five finalists in its Health Tech Competition to present innovative solutions for cardiovascular conditions. The selected companies will showcase their technologies during the 2025 Scientific Sessions, where a panel of expert judges will evaluate their presentations.
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Researchers have found that atrial electromechanical dissociation (AEMD) can predict stroke risk in people with transthyretin amyloid cardiomyopathy, even when the heart rhythm appears normal. A non-invasive assessment tool may help identify those at increased risk and guide earlier conversations about preventive strategies.
A study found that long-term use of melatonin supplements may increase the risk of heart failure, hospitalization, and death in adults with chronic insomnia. The research analyzed data from a large international database and found consistent and significant increases in serious health outcomes, even after balancing for other risk factors.
A preliminary study found that low-dose aspirin use was associated with a lower risk of major cardiovascular events, including heart attacks and strokes, among adults with Type 2 diabetes. The analysis of 11,500 individuals over 10 years showed that consistent aspirin use led to significant reductions in cardiovascular event rates.
A study found that following steps to improve cardiovascular health can reduce the risk of mild cognitive impairment and dementia among people with Type 2 diabetes. Maintaining optimal cardiovascular health may protect brain health even for individuals with a high genetic risk for dementia.
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Researchers found that combining three biomarkers – lipoprotein(a), remnant cholesterol, and high-sensitivity C-reactive protein – can reveal a nearly three-fold increase in heart attack risk. This combination approach may aid health care professionals in identifying individuals with high-risk profiles earlier.
Researchers developed an AI algorithm that accurately diagnosed multiple structural heart diseases from single-lead ECG sensors on smartwatches. The algorithm was trained on over 266,000 12-lead ECG recordings and prospectively validated in a real-world setting.
Cardiac rehabilitation significantly improves short and long-term recovery for heart surgery patients, but women participate less than men due to barriers such as lower referral rates, clinician bias, and caregiving responsibilities. The American Heart Association scientific statement calls for targeted interventions to improve enrollm...
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A naturally occurring gene called Cyclin A2, normally silenced in humans, can make new functioning heart cells and aid in the heart's repair. The breakthrough discovery could lead to new techniques for repairing damaged hearts as an alternative to transplants or implanted cardiac devices.
A study found a nearly linear relationship between nighttime light exposure and an increased risk of heart disease. The research suggests that reducing exposure to excessive artificial light at night can counteract the effects and may be a public health concern.
A new study found that combining GLP-1 receptor agonist medications with healthy lifestyle habits significantly reduces the risk of major adverse cardiovascular events, including heart attacks and strokes. The research suggests that adopting multiple healthy behaviors can lower cardiovascular risk even further.
The study found that men, Black patients, and those living in low socioeconomic areas were disproportionately affected by the increased amputation rates. The authors emphasize the need for aggressive prevention, early diagnosis, and intensive risk factor management to address the growing burden of diabetes and PAD.
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A new resource identifies genetic variants associated with elevated 'bad' cholesterol, a major contributor to heart disease. Clinicians can now predict patient risk for heart attacks and strokes, allowing for prevention and early treatment.
Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.
A new study from the University of Birmingham found that consuming flavanols can preserve blood vessel function in young healthy men during periods of uninterrupted sitting. The researchers tested whether high-flavanol cocoa could prevent FMD declines, and found significant protection against vascular dysfunction.
The Lehigh University team created a computational model to predict the hemodynamic response of patients with AFib, helping tailor neurostimulation dosages. The model validated against clinical data and predicted accurate effects on blood pressure, heart rate, and stroke volume.
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Research found acute and chronic viral infections increase risk of heart attacks and strokes, while long-term risks persist for HIV, hepatitis C, and herpes zoster. Vaccination measures, including flu shots, can reduce cardiovascular disease risk by 34%.
A novel post-translational modification, lactylation, plays a critical role in the pathogenesis of aortic dissection. Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha impairs ATP production and increases reactive oxygen species generation.
A study found that longer accumulations of steps in one go have a greater health benefit than short bouts spread out across the day. Walking continuously for 10-15 minutes per day was associated with lower risk of cardiovascular events and mortality.
A study found that super-high-pressure non-compliant balloons (NCB) are non-inferior to IVL balloon catheters for lesion preparation and stent expansion in severely calcified lesions. The results showed similar safety profiles and efficacy across various patient subgroups.
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A new study published in TCT 2025 reveals that at least 4.7 million people aged 65-85 living in the US have moderate or greater valvular heart disease (VHD), and at least 10.6 million have clinically significant VHD. The prevalence of VHD increases with advanced age, highlighting the need for screening and treatment programs.