A new study found that nudging both patients and providers with reminders increased flu vaccine numbers by almost 3,000 more people than expected. The researchers believe this could lead to strategies to boost annual flu vaccination rates.
Research suggests that blocking growth factor receptor signaling using cancer drugs may overcome two challenges: managing oral cancer pain and preventing opioid tolerance. This approach could control cancer while addressing pain through a non-opioid, biologically rational approach.
A team of University of Toledo physicists predicts significant growth for cadmium telluride photovoltaics in the US, with a target manufacturing capacity of 100 gigawatts by 2030. The technology offers advantages over silicon photovoltaics, including improved performance in hot and humid climates, and supports national energy security.
Researchers at Salk Institute debut an epigenetic catalog that shows genetic inheritance and life experiences have distinct effects on various types of immune cells, shedding light on individual differences in immune responses and potential new personalized therapeutics.
The four-year grant will provide educators with professional development training, create enduring resources, and develop virtual learning pathways for K-12 students. Over 1,000 teachers and 42,000 students in Nevada will benefit from the curriculum, materials, and resources.
The American College of Medical Genetics and Genomics announces Medical Genetics Awareness Week 2026, celebrating the power of collaboration in medical genetics. The week aims to bridge awareness gaps about the field and its professionals.
A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer, a deadly form of breast cancer lacking targeted therapies. The researchers identified dsRNA-binding proteins, specifically PACT, which suppress another protein called RNA-activated protein kinase (PKR).
A study by UC Riverside scientists reveals that the cysts of Toxoplasma gondii contain multiple distinct subtypes of parasites, each with different biological roles. This discovery offers new insights into how the parasite causes disease and why it has been difficult to treat.
A research team has developed a way to produce corticospinal-like neurons that centrally degenerate in motor neuron disease and are damaged in spinal cord injury. The study uses a multi-component gene-expression system called NVOF to precisely fine tune regulatory signals, resulting in mature neurons with distinct characteristics.
A newly excavated archaeological site in central China has uncovered evidence of advanced stone tool technologies, dating back 160,000-72,000 years ago, challenging long-held assumptions about early hominin behaviour in Eastern Asia. The findings suggest that hominins in this region were more inventive and adaptable than previously bel...
A new study in Geology suggests that massive undersea volcanism triggered at least four Triassic extinctions. Marine large igneous provinces were found to be a key driver of these events, accounting for half of the extinctions with an identifiable geological trigger.
A cohort study found that Medicaid expansion under the Affordable Care Act was associated with lower overall mortality among women with breast cancer aged 40-64. The benefits of expanded coverage were uneven, highlighting persistent disparities in healthcare access for certain populations.
Researchers have captured the first radio waves from a rare type of exploding star, revealing the star's final years. The discovery provides an unprecedented look at a massive star's behavior before its death in a supernova explosion.
The book sheds light on the often-ignored contributions of women in economics, highlighting their role as economic agents throughout history. Heggeness shares robust data and anecdotes about women who have thrived economically, from Taylor Swift to unsung heroes like Francis Perkins.
Researchers are developing next-generation adaptive insulin delivery systems using machine learning algorithms and ultra-rapid-acting U-500 insulin to personalize glucose control without manual intervention. The project aims to give people with Type 1 Diabetes their time, attention, and peace of mind back.
A nationwide survey found that 61% of Americans are unaware of non-statin medications to lower cholesterol, while 73% have never heard of lipoprotein(a) or coronary artery calcium score testing. Non-statin options include Ezetimibe, PCSK9 Inhibitors, and Bempedoic Acid, which can help patients at risk for heart disease.
The VERIFHE project aims to develop an open-source library for verifiable homomorphic encryption, enabling private and reliable inference. The ERC Proof of Concept grant will support the development of practical tools for machine learning services.
A new study discovered two previously unidentified fat distribution types associated with extensive gray matter atrophy and accelerated brain aging in men and women. Individuals with 'pancreatic-predominant' and 'skinny fat' profiles showed increased risk of neurological diseases, cognitive decline, and brain health issues.
The University of Virginia has launched a cross-Grounds initiative to advance health and healthcare through data and artificial intelligence. The Collaboratory aims to accelerate discovery, share expertise, and lower collaboration barriers across disciplines.
The MLEDGE project has successfully combined federated learning with cloud and edge computing to develop more secure, efficient, and personalized AI solutions. The project's applications include real-time COVID risk maps and energy consumption optimization in industry.
A large multinational clinical trial found that giving healthcare providers access to patient-reported outcome (PRO) data significantly improves the consistency of how treatment-related side effects are assessed in patients with cancer. This study highlights the importance of integrating the patient's voice into routine clinical evalua...
Researchers developed a high-resolution 3D ultrasonic imaging system for concrete that automatically adapts to different materials, improving contrast between defects and background material. The system uses a wide range of frequencies and can handle diverse materials without manual tuning.
Researchers at the University of Kansas have developed a tornado-forecast system called Warn-on-Forecast System (WoFS) that can predict tornado formation up to an hour before it occurs. The system uses high-resolution simulations and gauges uncertainties, providing guidance on severe weather threats.
Researchers developed miniature 3D tumor organoid models that closely mimic the human brain, revealing how glioblastoma interacts with surrounding brain cells and immune system. The models identified PTPRZ1 as a key regulator of tumor behavior, which helps determine its aggressiveness.
Researchers provide radiation oncologists with practical guidance to identify and protect female sexual organs during pelvic cancer treatment. The study establishes a shared, standardized approach to identifying the bulboclitoris, enabling clinicians to measure radiation dose to these tissues.
The Xigou site in central China has yielded evidence of sophisticated stone tool technologies dating back 160,000 to 72,000 years, revealing that hominins in the region were more innovative and adaptable than previously thought. The discovery challenges long-held views on early human technology in East Asia.
A hospital-based program supporting gun and knife violence victims can halve the likelihood of future harm, according to a Boston University study. Regular engagement with the Violence Intervention Advocacy Program reduced the risk of being revictimized or committing violence by 50 percent two to three years after discharge.
Rutgers University has developed a self-sustaining fund that reinvests revenue from commercialized technologies to support next-wave innovations. The model has generated an estimated 2.5-3.5 times more investment in follow-on funding.
Researchers used MRI analysis to measure glymphatic system activity, finding changes related to IIH stage and pressure levels. The findings suggest a noninvasive test could diagnose IIH more reliably, improving treatment options for patients with symptoms including headaches and vision loss.
A new computational modeling framework uses Type-3 Fuzzy Logic and neural networks to simulate tumor-immune dynamics under uncertainty and chaos. The model generates 'bands of uncertainty' and provides interpretable results, enabling physicians to understand the 'why' behind predictions.
Climate-risk scores are being used in infrastructure design, housing markets, and public policy, but the devil is in the details. Only 4% of highly cited studies shared their data and code, highlighting a structural barrier to cumulative progress.
Chronic wounds heal slowly due to healing disorders, affecting 800,000 people in Germany. Current treatment options lack evidence-based recommendations and patient-reported outcomes are underconsidered.
Researchers have uncovered a new understanding of how cardiac events are interconnected with the brain and nervous/immune systems. They found that sensory neurons in the vagus nerve detect injury and transfer signals to dedicated brain structures, leading to activation of the immune system.
Researchers led by Michael Wasserman are studying pesticide exposure in farming communities in Uganda, using household diaries and silicone wristbands to track human exposure. The study aims to inform communities about safe levels of exposure and suggest ways to reduce it.
Researchers have discovered a way to host graphene's electronic properties in a three-dimensional material, potentially removing hurdles for its use at scale in green computing. The discovery offers opportunities for designing materials with advanced low-energy electronic behaviour.
George Newman, a professor at the University of Toronto's Rotman School of Management, has been identified as an up-and-coming thinker whose ideas are predicted to make a significant impact on management thinking. His research focuses on creativity, identity, and meaning construction, with his work widely featured in prominent outlets.
Shorter-duration antibiotic therapy shows comparable success to longer-duration treatment in children with community-acquired pneumonia. However, more studies are needed for other age groups and diseases like acute otitis media.
A new study published in JAMA Network Open found that acupuncture is effective in reducing migraine without aura pain and improving functionality. The research identified specific brain network connections that predict treatment outcomes, enabling a personalized approach to pain management.
Researchers uncover a hypoxia–m⁶A–Gal-1 regulatory axis that fuels HCC progression by stabilizing Galectin-1 (Gal-1) mRNA, promoting malignant phenotypes. Functional experiments confirmed Gal-1's role in enhancing HCC cell proliferation, migration, invasion, and EMT-driven phenotypic plasticity.
The event brought together stakeholders to discuss improving support for students and graduates, with a focus on university-to-work transitions. Key findings highlighted the negative impact of COVID-19 on graduates' transitions and the importance of soft skills and cross-border employment opportunities.
JMIR Publications invites journalists, researchers, and experts to contribute to its News & Perspectives section with in-depth analysis and commentary on digital health trends. The publication aims to provide well-researched analysis that goes deeper than headlines, with a focus on factual precision, integrity, and empowerment.
A new framework for teaching critical consciousness in children's literature empowers kids to analyze texts with metaphorical concepts of mirrors and windows, fostering empathy and respect for diverse perspectives. The framework acknowledges different qualities of reflection, helping prevent prejudice and promoting social justice.
A Stanford University study found that showcasing past collective efforts on climate change can motivate individuals to take action. The most effective interventions combined evidence of impact with social and emotional benefits, increasing willingness to take public awareness actions by 30% and political actions by nearly 14%.
Researchers have made significant progress in developing AAV-mediated gene therapy for the inner ear, providing a potential cure for genetic forms of inner ear disorders. The approach targets specific cell types and aims to deliver functional genes to correct genetic defects or protect delicate sensory cells.
Researchers at the University of Rochester create a new process to turn ordinary metal tubes unsinkable by etching micro- and nano-pits on their surface, making them superhydrophobic. The tubes stay afloat in water, even when damaged or submerged for extended periods.
A study by SWPS University researchers found that sedentary lifestyle in adolescents can negatively impact their parents' mental health, leading to symptoms of depression. The study also showed that teenagers spend more time sitting than their parents, highlighting the need for family-based health-promoting interventions.
Researchers review EMT mechanisms and its impact on GBM progression, highlighting key signaling pathways and GSCs. EMT-targeted therapies offer promising strategies to disrupt tumor growth and enhance immune responses.
The Advanced Driving Simulation Center enables researchers to realistically test and optimize vehicles, chassis, and advanced driver assistance systems. The simulator's high bandwidth generates fine vibrations, crucial for optimizing electric vehicle comfort.
A new standardized protocol for preoperative CT assessment of the submental artery's origin and course has been developed, enabling precise visualization of its vascular course and caliber. This systematic approach aims to tailor flap design for individual patients, minimizing intraoperative surprises and optimizing outcomes.
The organization aims to support research and therapies that help people live fully and meaningfully despite serious illnesses. The awarded projects focus on delivering psychedelic therapy for anxiety reduction and improving end-of-life care, with the goal of promoting compassion and dignity.
A new study from the University of Michigan found that used electric vehicles (EVs) currently offer the lowest lifetime cost of ownership, with significant savings for drivers. The researchers analyzed virtual vehicle models, monthly gas and electricity prices, and Craigslist data to determine the total cost of ownership for different ...
Two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, advance genetic mutation detection in cancer diagnostics and RNA-based genomic studies. The tools improve accuracy and accessibility of genomic analysis, opening new horizons for precision medicine and genomic discovery.
Researchers from Adelaide University review the future of optical atomic clocks, finding them one of the most precise measurement tools ever built. The technology has advanced rapidly over the past decade and is well-positioned to become the gold standard for timekeeping, provided technical challenges are addressed.
A new tool developed by WSU researchers uses artificial intelligence to predict daily and weekly snow-water equivalent, outperforming existing methods for about 90% of locations. The tool provides critical information for short- and long-term water management decisions in the Western US.
Research reveals that Sulf1 is essential for both reward-dependent and aversion learning, highlighting its critical role in adult brain function. The enzyme acts through distinct dopamine D1 and D2 receptor pathways, underscoring its importance in neural circuits involved in learning.
A recent study combines heart imaging with proteomics to identify key proteins associated with cardiovascular diseases, offering new insights into pathogenesis and therapeutic development. The research highlights four plasma proteins, AGER, CCN3, FER, and SPON1, as high-priority candidates for drug targeting.
A Swedish study of prematurely born adults found increased morbidity in physical and mental health, yet they reported a high quality of life. The study, which followed participants from birth to age 26-29, suggests that premature birth does not necessarily limit daily life.
The University of Hong Kong (HKU) has established the Hong Kong Base of the State Key Laboratory of Subtropical Building and Urban Science, a comprehensive platform integrating scientific research, talent cultivation, and social service. The base aims to advance subtropical architecture and urban science research, promoting sustainable...
Researchers at the University of Oulu have identified genes associated with an increased risk of pneumonia, including those related to nicotine dependence in older adults. The study used genetic data from over 600,000 individuals to examine causal relationships between smoking, obesity and pneumonia risk.
The University of Hong Kong (HKU) has signed a Memorandum of Understanding (MoU) with the Qatar Foundation's Academic Bridge Program to promote student mobility and collaborative academic initiatives. The partnership aims to support student exchanges, credit transfer options, and joint training programs between HKU and Qatar.