Articles tagged with Cell Pathology
The American Association for Cancer Research (AACR) has awarded its inaugural Team Science Award to a multidisciplinary team of researchers from the University of Michigan and Harvard Medical School/Brigham and Women's Hospital. The award recognizes their groundbreaking discovery of gene fusions in prostate cancer, which has significan...
Researchers identified a connection between pregnane X receptor (PXR) and neuroprotection in a mouse model of Niemann-Pick type C disease. Activating PXR with known activators, such as dilantin and St. John's Wort, may help clear toxic cholesterol byproducts.
Researchers at Rockefeller University discovered that calnexin plays a crucial role in forming the ?IIb?3 receptor complex. The study highlights the importance of calnexin in protein folding and degradation, which may lead to new strategies for treating common diseases.
A new study shows that hydroxyurea is an efficient and safe treatment option for young children with sickle cell anemia, improving spleen function and reducing acute chest syndrome incidents
A recent study found that circulating stem cells contribute less than 1% to lung repair, while most contributions come from lung-resident stem cells. The study also suggests a link between the number of Y-chromosome containing pneumocytes and acute cellular rejection in lung tissue.
Studies in mice with genetically engineered mutant huntingtin protein found that widespread production led to locomotor problems, neurodegeneration, and abnormal brain connections. Conversely, restricted production showed little difference from normal mice, suggesting cellular interactions play a significant role in HD pathogenesis.
Researchers at Rice University aim to create implantable TMJ discs grown from patient cells, offering a potential alternative to transplantation. The goal is to provide a treatment option for the nearly 11 million Americans suffering from TMJ disorders.
Researchers at UT Southwestern have made significant progress in understanding lipodystrophies, rare disorders characterized by partial or total loss of fat tissues. Recent studies have identified gene mutations and novel therapeutic approaches for these patients, which may also be applicable to obese individuals with abnormal fat dist...
A study has identified a genetic mutation in MCFD2 that causes a rare bleeding disorder by disrupting the transport of clotting factors V and VIII. The researchers propose a new therapeutic target, suggesting a potential alternative to existing anticoagulants.