Articles tagged with Chronic Pain
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A WSU study found that stopping long-term opioid therapy does not make chronic, non-cancer-related pain worse, and in some cases, improves it. The researchers analyzed data from 551 VA patients who discontinued opioid therapy for at least a year, finding that their pain did not worsen but rather remained similar or improved slightly.
A study published in JNeurosci found that activating the BLA-CeA circuit counteracted anxiety- and depression-like behaviors in rats, even without physical pain. This discovery sheds light on the complex relationship between pain and emotion, potentially leading to better treatments for chronic pain patients.
Two studies presented at EULAR 2018 found that sleep problems predict the onset of chronic widespread pain and are associated with chronic pain in adolescents. Sleep difficulties, fatigue, and anxiety were identified as key predictors of chronic pain.
A Kaiser Permanente study of nearly 2,500 patients found that reducing opioid doses for chronic pain did not result in lower patient satisfaction scores. Most encounters resulting in an opioid dose reduction maintained favorable overall satisfaction.
Researchers discovered a naturally occurring protein called apolipoprotein A-I binding protein (AIBP) that inhibits inflammatory response underlying chronic pain processing. A single spinal injection of AIBP alleviated chemotherapy pain in mice for two months with no side effects.
A systematic review and meta-analysis found that psychological interventions using cognitive behavioral approaches can reduce chronic pain intensity and improve self-efficacy in older adults. However, the study's limitations highlight the need for further research to develop more effective treatments.
Researchers created PainTracker, a pain assessment adaptable to primary care clinics, addressing patient treatment history, goals and expectations, pain intensity and quality-of-life issues. The tool has dramatically transformed doctors' ability to assess and manage chronic pain, with 40-60% of patients having inadequate pain management.
Researchers found that older influential men and educated individuals were more likely to support female genital cutting, highlighting the need for targeted campaigns. The study provides new insights into addressing this practice through culturally sensitive approaches.
A recent study found that Veterans Health Administration (VHA) facilities have varying care practices for military veterans with chronic pain, leading to inconsistent rates of long-term opioid therapy. Facilities with a wider range of non-opioid treatment options had lower rates of opioid use among veterans.
A new study by the University of Colorado Boulder found that post-surgical opioids can lead to chronic pain in rats for more than three weeks. The researchers discovered that opioids stimulate specialized immune cells in the spinal cord, making them more reactive to pain, and that gradual tapering has no effect on the prolonged pain.
Researchers at the University of Pennsylvania found that hunger suppresses chronic pain by targeting specific brain cells. The study discovered that activating a group of 300 neurons responsible for prioritizing hunger over pain significantly reduced inflammatory pain responses, while acute pain responses remained intact.
A new trial suggests that tai chi is a viable alternative to aerobic exercise for managing chronic pain, particularly for those with fibromyalgia. The study found that participants who received tai chi showed significant improvements in symptoms compared to those who exercised aerobically.
Researchers uncover mechanism behind neuropathic pain and develop innovative treatment blocking FLT3 molecule. The treatment shows immediate and long-lasting therapeutic effects in animal subjects, reducing hyperalgesia and allodynia.
A recent study found that a specific manipulation of dopamine receptors impairs chronic pain in male mice but has no effect on females. The researchers suggest that different types of cells drive the development of pain in males and females, leading to the potential for sex-specific pain relief medications.
Researchers at UIC will study molecular neurobiology of chronic pain and develop new drug treatments for sickle cell disease patients experiencing chronic pain. The funding aims to understand the role of protein kinases in chronic pain and identify potential therapeutic targets.
Researchers found that literacy-adapted group cognitive behavior therapy (CBT) and simplified pain education (EDU) significantly improved pain and physical function in patients with chronic pain. The study suggests that CBT can be simplified to improve accessibility without reducing its potency.
Researchers at the Max Planck Institute found that Jymmin increases pain threshold by up to 50% and reduces anxiety in chronic pain patients. The combination of physical exertion and music triggers endorphin release, making users more tolerant to pain.
A Kenyan pilot study reveals a significant link between chronic pain and glutamate consumption, with participants experiencing improved symptoms after reducing MSG intake. The findings support the potential of dietary changes as an effective low-cost treatment option for developing countries.
Hyperreactive brain networks may contribute to the hypersensitivity of fibromyalgia. Researchers found that patients with fibromyalgia have brain networks primed for rapid responses to minor changes, leading to explosive synchronization.
A study found that genetic variations account for 7-12% of chronic postsurgical pain cases, while clinical risk factors like age and sex contribute to 3-6%. Patients under 65 years old, males, and those with a prior history of chronic pain were at increased risk.
A new study establishes expert consensus on managing concerning behaviors in patients taking opioids for chronic pain, including assessing risk and safety concerns, identifying pain symptoms, and providing patient education. The study also highlights the importance of referral to other pharmacologic and non-pharmacologic therapies.
A study of over 13,000 opioid overdose deaths found that individuals with chronic pain conditions were at the highest risk of death. The study also reveals that many who died had been diagnosed with depression and anxiety, highlighting the importance of early intervention for those at high risk of fatal overdose.
Cognitive behavioral therapy (CBT) is an effective treatment for chronic pain that can reduce reliance on opioids and improve quality of life. By teaching patients coping strategies, CBT helps them manage their pain and behaviors associated with it.
Researchers found widespread disruptions in brain white matter across several regions, linked to higher pain levels and fatigue. The study suggests poor white matter health may contribute to persistent widespread pain experienced by Gulf War veterans.
A new $9 million study will compare two approaches to relieving noncancer chronic pain and reducing opioid use. The study will assess which approach leads to lower or discontinued opioid use and greater pain relief among people who have been using opioids over the long term.
Researchers adapted an Integrative Medical Group Visit approach to address chronic pain, fatigue, and depression in low-income Spanish-speaking Latinos. The program combined complementary and integrative medicine, medical group visits, and mindfulness-based stress reduction techniques, showing significant benefits.
A study of 690 women found that both short and long surgical incisions for cesarean births are associated with increased pain after delivery. The authors recommend an optimal range of 12-17cm for cesarean incision length to minimize post-delivery pain.
Chronic pain affects 39-85% of people living with HIV, with neuropathic pain being a significant concern. Guidelines recommend a multidisciplinary treatment approach using non-drug options such as cognitive behavioral therapy, yoga, and physical therapy.
The Krembil Research Institute and University Health Network release new guidelines discouraging brain imaging as a test for chronic pain. Brain imaging is considered unreliable due to variability between people and within individuals, making it unsuitable as a 'lie detector' test.
A recent study found that almost all antidepressants present significant side effects, but some individuals may better tolerate certain side effects. Personalized medicine is recommended to match chronic pain patients with suitable antidepressant medication, taking into account their individual health profiles and existing health issues.
The scientific evidence on cannabis for chronic pain and post-traumatic stress disorder (PTSD) is inconclusive, with only low-strength evidence suggesting potential benefits. However, researchers found significant risks associated with cannabis use, including increased risk of motor vehicle accidents and psychotic symptoms.
Researchers at Albert Einstein College of Medicine and Montefiore Health System are conducting a five-year study to test whether medical marijuana reduces opioid use among adults with chronic pain. The study will enroll 250 HIV-positive and HIV-negative adults who use opioids and have received certification for medical marijuana use.
Scientists at McGill University have discovered a new biological pathway involved in pain processing, which could lead to the use of existing cancer drugs as alternatives to opioids. The researchers found that EGFR blockers were as potent analgesics as morphine in mouse models of inflammatory and chronic pain.
A team-based primary care model, TOPCARE, has been shown to decrease prescription opioid use among patients with chronic pain by 40 percent. This study, conducted in four primary care practices, found that TOPCARE patients had lower opioid doses and were more likely to adhere to AAPM guidelines.
Dose reduction in long-term opioid therapy for chronic pain improves pain, function, and quality of life. Multidisciplinary pain programs incorporating behavioral interventions can enhance patient outcomes.
A study of post-surgical patients found that those who received psychological support showed significant reductions in opioid use, depression, and daily disruptions due to pain. Patients learned coping skills grounded in Acceptance and Commitment Therapy, promoting mindfulness and acceptance of difficult experiences.
Researchers at Cleveland Clinic conducted the first randomized controlled trial of DBS for neuropathic pain, targeting brain structures related to emotion and behavior. The study showed significant improvements in indices of depression, anxiety, and quality of life, suggesting a potential shift away from analgesia-based treatments.
A study by the American Society of Anesthesiologists found that women who catastrophize, or exaggerate pain, are more likely to take prescribed opioids than men. The study suggests that early treatment for pain catastrophizing may reduce opioid prescriptions for both sexes.
Researchers at UCSF found a significant association between chronic pain and faster declines in memory function and increased risk of dementia in older adults. The study suggests that chronic pain could be related to changes in the brain contributing to cognitive decline.
New research suggests that breastfeeding for over 2 months reduces the risk of chronic post-C-section pain. Mothers who breastfed longer had lower rates of persistent pain compared to those who breastfed for less time. The study also found a significant association between anxiety during breastfeeding and increased risk of chronic pain.
A recent study by Columbia University's Mailman School of Public Health found that approximately half of adults with anxiety or depression also experience chronic pain. Chronic physical conditions were most common among individuals with mood disorders, followed by respiratory diseases and cardiovascular disease.
A study led by Columbia University Medical Center has shown that chronic pain may occur when pain receptors migrate from the nerve cell's surface to the cell's inner chambers. This discovery may lead to the development of a new class of medications for chronic pain that is more potent and less prone to side effects.
Dr. Michael Stanton-Hicks is a pioneer in the management of complex regional pain syndrome (CRPS), with extensive contributions to neurostimulation and chronic pain research. He has bridged advances in neurostimulation, taxonomizing CRPS, and improved patient care through his work at the Cleveland Clinic.
Researchers found that chronic pain distorts the intensity of pain perception in other body parts by rewiring circuits in the anterior cingulate cortex. This causes a greater reaction to painful stimuli throughout the body, with far-reaching consequences for mental health and disease treatment.
Psychologist Robert Gatchel's research highlights how patients' irrational beliefs about chronic pain can impact treatment outcomes and pain management. His work suggests that a more comprehensive approach to treatment is needed, incorporating lifestyle habits, attitudes, and social support systems.
A new study published in Pain found that opioid use among Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn veterans is comparable to the general US population. Chronic pain management with opioids was strongly associated with PTSD, major depressive disorder, tobacco use, and rural residence.
A new study reveals that acupuncture improves carpal tunnel syndrome symptoms by rewiring the primary somatosensory cortex in the brain. Real acupuncture at the affected hand led to measurable improvements in outcomes and long-term symptom relief, while sham acupuncture had no physiologic effects.
A new study published in the BMJ Journal for Medical Humanities found that shared reading can be a useful therapy for chronic pain sufferers. The study compared shared reading to cognitive behavioral therapy (CBT) and found that shared reading provided a more comprehensive approach to managing emotional pain.
A novel non-pharmacological approach using green LED has shown promising results in treating neuropathic pain in rats with no side effects observed. The therapy may work by increasing levels of endogenous opioids, which inhibit pain and decrease inflammation.
A study published in PAIN found that physically active older adults have lower pain perception and better ability to block responses to painful stimuli. This suggests that low levels of sedentary behavior and greater light physical activity may be critical in maintaining effective endogenous pain inhibitory function.
Researchers at CU Boulder have developed a functional MRI-based model that identifies brain activity patterns involved in varied pain experiences. The model, called SIIPS1, maps positively correlated and negatively correlated brain sub-regions, including regions not traditionally considered important for pain assessment.
A new study reveals that poorer and less-educated older Americans are more likely to experience severe chronic pain, even after accounting for age. The research also shows that people with lower levels of education and wealth are more likely to experience pain-related disability.
A Washington State University-led study explores the relationship between sleep and chronic pain, with the goal of developing new treatments. The research aims to understand which comes first: pain or poor sleep, and whether improving sleep can alleviate pain symptoms.
A novel study at the University of Warwick aims to design a package of care and support for people with chronic pain to overcome obstacles to returning to work. The study will use Individual Placement Support (IPS) and provide work placements, aiming to improve health outcomes and quality of life.
Researchers explore therapeutic interventions like light, sound, and electrical energy to resynchronize damaged neurons in the brain. Neuroplasticity can be harnessed to treat a range of conditions, from bad habits to chronic pain syndromes.
A study led by Indiana University researcher Andrea Hohmann found a compound that reduces chronic pain in mice without addiction risk or 'marijuana high'. The compound modulates the brain's cannabis receptors and amplifies the therapeutic effect of endocannabinoids.
A new study published in Journal of Pain Research found that implementation of the Stepped Care Model for Pain Management resulted in clinically significant improvements in quality of pain care outcomes, including increased provider knowledge and referrals to behavioral health providers. The model's individualized approach has the pote...
A recent study published in Science Advances found that over 85% of pain-sensing neurons are sensitive to one specific type of painful stimulus. This challenges previous findings suggesting most neurons respond to all types of pain.
Researchers at The University of Manchester have discovered a potential therapy for alleviating chronic pain by tuning the brain's frequency. This new approach uses visual and auditory stimulation to reduce pain intensity in patients.
The National Institutes of Health has awarded a $7.5 million grant to researchers at the University of Michigan to study chronic pain. The team aims to investigate how peripheral damage, inflammation, and central nervous system factors interact to cause chronic pain, with potential breakthroughs in treating high levels of chronic pain