Articles tagged with Covid 19
Researchers have identified molecular mechanisms by which osteoporosis medications protect against Covid-19. The study suggests that compounds like alendronate and zoledronate may be beneficial in preventing SARS-CoV-2 infection and related hospitalizations.
Researchers at the University of São Paulo's Medical School have developed a COVID-19 vaccine using virus-like particles (VLPs), which proved highly protective, safe, and versatile in animal trials. The vaccine can be easily updated to combat variants of concern without requiring an adjuvant.
A new analysis of US mortality data shows men are most likely to die from traumatic brain injuries (TBI), with rates over three times higher than women. Older adults and specific racial and ethnic groups, such as American Indian or Alaska Native people, also face a higher risk of fatal TBI-related deaths.
A recent study highlights the need for targeted interventions to improve COVID-19 vaccine confidence among Black women in the US. Addressing historical traumas and providing clear safety information are crucial to building trust with this demographic.
Researchers found that up to 34% of the British public considered acts like nepotism or bribery acceptable during the vaccine rollout. The study also discovered an association between public tolerance of petty corruption and vaccine rollout speed, with slower rollouts in areas where tolerance was higher. Lead author Dr Franziska Sohns ...
The Community and Household Acute Respiratory Illness Monitoring (CHARM) Network will track how respiratory illnesses spread over time, assess immune responses, and study household transmission. UC San Diego will enroll 2,000 individuals and serve as the centralized data hub, providing insights to inform public health responses.
The study found that COVID-19-related disruptions led to frequent delays in investigations or treatments for children with brain tumors. Caregivers reported feeling traumatized by their experiences, including lack of access to healthcare facilities and social situations, which made it harder to evaluate their concerns.
The prevalence of substance use disorder surged during the COVID-19 pandemic, but treatment receipt declined initially due to healthcare disruptions. Treatment rates began to recover in 2022, likely driven by reopened treatment programs and increased telehealth use.
A new study from Johns Hopkins APL suggests that robust and rapid test development, production, and distribution are crucial for addressing future public health threats. The research found that public-private partnerships saved an estimated 1.4 million lives in the US during the COVID-19 pandemic.
A new system can quickly identify emerging virus variants and provide information on their genetic changes, helping to understand why they spread differently in human populations. This enables the development of more effective vaccines and targeted treatments for diseases such as flu, COVID, and tuberculosis.
A cohort study found COVID-19 accelerates kidney function decline, particularly in hospitalized patients. Early monitoring and optimized management of chronic kidney disease can help prevent complications.
According to a new survey, over half of U.S. adults believe the RSV vaccine is effective in protecting infants from the virus, up from 42% last year. The rise in perceived effectiveness comes as several politicians have cast doubt on the vaccine's safety and efficacy.
A study by the University of Surrey found that high-quality face masks reduce transmission risk by ninefold and doubling indoor air ventilation cuts it by nearly a third. Improving ventilation and physical distancing further minimizes the risk.
A new study reveals the COVID-19 pandemic led to a sharp decline in hospital visits for acute coronary syndrome, particularly among older adults and women. The research emphasizes the need for targeted interventions to ensure access to critical care during future emergencies.
The study highlights cultural defaults, such as individualism and social choice, which led to divergent COVID-19 responses in the US and East Asian countries. These cultural factors contributed to massive variations in COVID-related deaths, with East Asian countries experiencing significantly lower death tolls.
A randomized clinical trial found that a brief outpatient rehabilitation program improved physical function in patients with post-COVID condition. The intervention showed sustained benefits over time, with negligible adverse effects.
The COVID-19 pandemic and lockdown created space for trans and gender diverse youth to explore and resolve their gender identity, with the most prevalent theme being a 'time for identity development'. This research found largely positive impacts on gender identity development in this age group.
A recent study from Trinity researchers uncovers the mechanisms behind COVID-19 disease severity, highlighting the critical role of low-density neutrophils. The findings suggest that lingering immune abnormalities after recovery could contribute to long-term health effects or complications.
Research from Radboud University Medical Center shows that lockdowns during the COVID-19 pandemic strengthened the immune system's response to microorganisms. The study found that after lockdowns, inflammation levels in the body were low but the immune system reacted more intensely to viruses and bacteria.
A recent study in the Netherlands has found that COVID-19 vaccination during pregnancy is not associated with adverse health outcomes in infants. The researchers analyzed data from over 3,600 participants and found no significant associations between maternal COVID-19 vaccination and neonatal health issues, including breathing difficul...
A study analyzed police data in Atlantic City, NJ before and after the start of the pandemic, finding a temporary reduction in dispatched calls for mental health services. Police-initiated contact also decreased slightly after restrictions began, but no long-term trend was found.
Adult obesity trends in the US have declined for the first time in more than a decade, according to recent data. The South region experienced the largest decreases in body mass index and obesity prevalence, despite also facing high COVID-19 mortality rates among obese individuals.
A recent study found that post-COVID-19 condition (PCC) affects approximately 8.4% of US adults, with significant differences observed across various demographic groups. Currently, 3.6% of adults have PCC, and a notable 2.3% experience activity-limiting PCC.
The Pfizer-BioNTech XBB vaccine provided protection against severe COVID-19 cases and hospitalizations among children aged 5-17 during the 2023-2024 season. The vaccine showed an estimated vaccine effectiveness of 63-73% in preventing severe illness.
Researchers discovered a protein variant acting like a tuning dial to regulate interferon signaling, impacting immune function and disease susceptibility. The balance between this variant and the normal protein may vary from person to person, contributing to individual differences in immune responses.
A new national study reveals that loneliness and social isolation have returned to pre-pandemic rates for older Americans, affecting 33% of adults aged 50-80. Those with poor physical or mental health face even higher rates, highlighting the need for clinicians to screen patients for these issues and connect them with community resources.
Researchers at Rockefeller University have identified a novel class of antivirals that target a type of enzyme essential to SARS-CoV-2 infections and many RNA viruses, including Ebola and dengue. The findings may pave the way for a faster and more robust response to future pandemics.
A new study by Kaunas University of Technology found that NGOs' financial adaptations during the COVID-19 pandemic were crucial for their success. Key factors contributing to financial success included working with governments, virtual fundraising, and publicity.
A study found that more than half of laws and policies on healthcare workers' rights align with global standards. However, gaps persist in areas such as fair pay, occupational health and safety, mental health services, and non-discrimination protections.
Countries that took measures early experienced lower excess mortality rates and coped better economically. A surveillance system capable of quickly tracking virus spread is crucial for effective response.
A recent study found that US older adults aged 50-80 commonly experience loneliness and social isolation, with high rates reported across various sociodemographic groups. These findings highlight the significant impact of social isolation on physical and mental health in this age group.
Researchers at University of Helsinki and colleagues have mapped the 'hijackome', detailing how SARS-CoV-2 variants exploit specific cellular pathways to spread and evade immune defenses.
Scientists at The Jackson Laboratory have identified the CAST/EiJ mouse as a highly susceptible model for studying severe COVID-19. This genetically pure background allows researchers to investigate the virus's impact without artificial receptor modifications, mirroring human responses. Initial trials using antiviral treatments show pr...
A study found that psilocybin-assisted psychotherapy significantly reduced depression among clinicians providing front-line COVID-19 care. The treatment was more effective than a placebo, with participants experiencing greater reductions in symptoms over time.
A study published in PLOS Global Public Health found that individuals with high credulity are more susceptible to fake news and vaccine hesitancy. Mistrust was also linked to conspiracy thinking and difficulty distinguishing between real and fake news, particularly in those exposed to childhood adversity.
Dartmouth researchers propose a new way of thinking about masking and social distancing rules using game theory, considering them as two distinct actions. The study finds that people respond differently to these measures based on their perception of the disease's severity, trending towards masking or no protective action over time.
An experimental study in mice found that SARS-CoV-2 infection can damage the retinas, leading to long-term implications for vision. The virus caused widespread inflammation across the retinal pigment epithelium, including complement activation and increased production of inflammatory cytokines.
A study by Weill Cornell Medicine researchers found that SARS-CoV-2 virus infection causes significant damage to mitochondria in infected cells, leading to an overactive renin-angiotensin-activation-system (RAAS) and associated blood clotting. This damage contributes to the multi-organ damage seen in severe COVID-19.
Researchers at McGill University have discovered that pregnancy enhances the body's natural immunity to block severe flu infection. By activating a powerful molecule in the nasal cavity, pregnant women may benefit from stronger antiviral defenses against the Influenza A virus.
Researchers found that SARS-CoV-2 disrupts mitochondrial reactions, leading to immune sensor activation and a cytokine storm, which triggers multiple organ-damaging events. Autopsy samples revealed extensive inflammation and organ damage in organs such as the heart, lungs, and kidneys.
A new study by the University of Birmingham found that Covid-19 public health measures led to a significant decrease in stranger sex offenses, particularly those involving night-time economy and outdoor settings. The research also showed a reduction in offences taking place at home and internet-facilitated crimes during lockdowns.
Researchers have discovered a monoclonal antibody capable of targeting multiple SARS-CoV-2 variants, including recent Omicron strains. K4-66's exceptional ability to adapt to the virus's frequent mutations makes it a promising candidate for vaccine and therapy development.
A study found stopping universal masking and SARS-CoV-2 testing led to a significant increase in hospital-onset respiratory viral infections compared to community cases. Restarting health care worker masks significantly reduced the risk of these infections.
A new study found that exposure to air pollutants like PM2.5 and PM10 increases the risk of persistent long-COVID symptoms, which can last for months or even years after a COVID-19 infection. Vaccination was shown to reduce this risk.
Researchers at the University of Illinois have created a DNA-made nanorobot called NanoGripper that can pick up COVID-19 viruses for rapid detection and block viral particles from entering cells. The device also has potential applications in cancer treatment and preventive medicine.
A study of 49 million patients in England found that routine screening for cardiometabolic conditions like obesity and high blood pressure dropped sharply during the pandemic. Blood pressure measurements remained lower than pre-pandemic levels as of March 2024, particularly among lower socioeconomic groups.
Researchers at USF Health have created the first ever peer-reviewed guide to audio podcasts dedicated to infectious diseases. The study highlights 38 popular infectious disease-oriented audio podcasts, including a new USF Health series called Contagion: An Infectious Diseases Podcast.
A study by researchers at the University of Pennsylvania School of Medicine found that online health care reviews on Yelp have not fully recovered from the COVID-19 pandemic. The analysis shows a significant decline in positive reviews, particularly among rural facilities and those serving areas with higher proportions of Black or Hisp...
A survey of Oregon's Medicaid and Medicare beneficiaries found that housing and food insecurity rose sharply during the pandemic, despite a significant increase in spending. The study suggests that addressing social needs during healthcare visits can improve health outcomes and reduce costs for taxpayers.
A study found that Oregon's COVID-19 stay-at-home order led to a significant increase in reported health-related social needs, including housing and food. The analysis suggests that public health interventions are needed to address these persistent needs.
A serial cross-sectional study found a significant decrease in positive reviews for health care facilities post-COVID, highlighting disparities in patient experience. The disparity is particularly pronounced in rural areas with high proportions of Black and white residents.
Life expectancy in the USA varies by more than 20 years depending on an individual's race and ethnicity and where they live. Researchers found that marginalized groups already had lower life expectancy, and the pandemic further increased the gap.
A recent study using regression discontinuity found that COVID-19 rates were higher among school-eligible children compared to those not eligible during in-person semesters. However, the difference decreased with each semester, and transmission was lower among school-eligible children during summer breaks.
A recent longitudinal study from the University of Toronto reveals that older adults with migraine are at a substantial increase in risk of depression during the pandemic. Increased family conflict, difficulties in accessing healthcare, and caregiving responsibilities were associated with higher risks of depression among this population.
A global team, including Lehigh University researcher Xuanhong Cheng, is exploring molecular- and cellular-level changes in muscle tissue that could lead to better diagnostic tools and therapeutic options for CFS and long COVID. The team aims to develop noninvasive diagnostic tools using electrical signatures.
Researchers have discovered that seemingly 'broken' genes in coronaviruses are retained due to their functional role beyond protein production. These extra genes help control the activity of other viral genes.
A Saint Louis University study found that COVID-19 stay-at-home orders facilitated easier breastfeeding, stronger mother-child bonding, and extended breastfeeding duration for many women. However, the pandemic also presented significant barriers, including limited access to lactation support and heightened maternal stress.
The study found that high oxygen therapy modalities increased oxidative stress and lung injury in patients with severe COVID-19 pneumonia. Patients who died of COVID-19 had significantly higher mean MDA levels than those who survived.
Researchers at Tokyo University of Science have successfully captured viral infection process under a light microscope using the giant Mimivirus. The footage showcases the proliferation of the virus and its release from cells, highlighting its biological significance in ecosystems.
The Portland State report highlights the positive impact of Project Turnkey shelters, which provide a sense of community and stability for residents. By offering private rooms, food, and hygiene supplies, as well as on-site case management, these sites help guests begin to imagine their future and make plans for stable housing.