Articles tagged with Covid 19
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Researchers discovered a protein variant acting like a tuning dial to regulate interferon signaling, impacting immune function and disease susceptibility. The balance between this variant and the normal protein may vary from person to person, contributing to individual differences in immune responses.
A new national study reveals that loneliness and social isolation have returned to pre-pandemic rates for older Americans, affecting 33% of adults aged 50-80. Those with poor physical or mental health face even higher rates, highlighting the need for clinicians to screen patients for these issues and connect them with community resources.
Researchers at Rockefeller University have identified a novel class of antivirals that target a type of enzyme essential to SARS-CoV-2 infections and many RNA viruses, including Ebola and dengue. The findings may pave the way for a faster and more robust response to future pandemics.
A new study by Kaunas University of Technology found that NGOs' financial adaptations during the COVID-19 pandemic were crucial for their success. Key factors contributing to financial success included working with governments, virtual fundraising, and publicity.
A study found that more than half of laws and policies on healthcare workers' rights align with global standards. However, gaps persist in areas such as fair pay, occupational health and safety, mental health services, and non-discrimination protections.
Countries that took measures early experienced lower excess mortality rates and coped better economically. A surveillance system capable of quickly tracking virus spread is crucial for effective response.
A recent study found that US older adults aged 50-80 commonly experience loneliness and social isolation, with high rates reported across various sociodemographic groups. These findings highlight the significant impact of social isolation on physical and mental health in this age group.
Researchers at University of Helsinki and colleagues have mapped the 'hijackome', detailing how SARS-CoV-2 variants exploit specific cellular pathways to spread and evade immune defenses.
Scientists at The Jackson Laboratory have identified the CAST/EiJ mouse as a highly susceptible model for studying severe COVID-19. This genetically pure background allows researchers to investigate the virus's impact without artificial receptor modifications, mirroring human responses. Initial trials using antiviral treatments show pr...
A study found that psilocybin-assisted psychotherapy significantly reduced depression among clinicians providing front-line COVID-19 care. The treatment was more effective than a placebo, with participants experiencing greater reductions in symptoms over time.
A study published in PLOS Global Public Health found that individuals with high credulity are more susceptible to fake news and vaccine hesitancy. Mistrust was also linked to conspiracy thinking and difficulty distinguishing between real and fake news, particularly in those exposed to childhood adversity.
Dartmouth researchers propose a new way of thinking about masking and social distancing rules using game theory, considering them as two distinct actions. The study finds that people respond differently to these measures based on their perception of the disease's severity, trending towards masking or no protective action over time.
An experimental study in mice found that SARS-CoV-2 infection can damage the retinas, leading to long-term implications for vision. The virus caused widespread inflammation across the retinal pigment epithelium, including complement activation and increased production of inflammatory cytokines.
A study by Weill Cornell Medicine researchers found that SARS-CoV-2 virus infection causes significant damage to mitochondria in infected cells, leading to an overactive renin-angiotensin-activation-system (RAAS) and associated blood clotting. This damage contributes to the multi-organ damage seen in severe COVID-19.
Researchers at McGill University have discovered that pregnancy enhances the body's natural immunity to block severe flu infection. By activating a powerful molecule in the nasal cavity, pregnant women may benefit from stronger antiviral defenses against the Influenza A virus.
Researchers found that SARS-CoV-2 disrupts mitochondrial reactions, leading to immune sensor activation and a cytokine storm, which triggers multiple organ-damaging events. Autopsy samples revealed extensive inflammation and organ damage in organs such as the heart, lungs, and kidneys.
A new study by the University of Birmingham found that Covid-19 public health measures led to a significant decrease in stranger sex offenses, particularly those involving night-time economy and outdoor settings. The research also showed a reduction in offences taking place at home and internet-facilitated crimes during lockdowns.
Researchers have discovered a monoclonal antibody capable of targeting multiple SARS-CoV-2 variants, including recent Omicron strains. K4-66's exceptional ability to adapt to the virus's frequent mutations makes it a promising candidate for vaccine and therapy development.
A study found stopping universal masking and SARS-CoV-2 testing led to a significant increase in hospital-onset respiratory viral infections compared to community cases. Restarting health care worker masks significantly reduced the risk of these infections.
A new study found that exposure to air pollutants like PM2.5 and PM10 increases the risk of persistent long-COVID symptoms, which can last for months or even years after a COVID-19 infection. Vaccination was shown to reduce this risk.
Researchers at the University of Illinois have created a DNA-made nanorobot called NanoGripper that can pick up COVID-19 viruses for rapid detection and block viral particles from entering cells. The device also has potential applications in cancer treatment and preventive medicine.
A study of 49 million patients in England found that routine screening for cardiometabolic conditions like obesity and high blood pressure dropped sharply during the pandemic. Blood pressure measurements remained lower than pre-pandemic levels as of March 2024, particularly among lower socioeconomic groups.
Researchers at USF Health have created the first ever peer-reviewed guide to audio podcasts dedicated to infectious diseases. The study highlights 38 popular infectious disease-oriented audio podcasts, including a new USF Health series called Contagion: An Infectious Diseases Podcast.
A study by researchers at the University of Pennsylvania School of Medicine found that online health care reviews on Yelp have not fully recovered from the COVID-19 pandemic. The analysis shows a significant decline in positive reviews, particularly among rural facilities and those serving areas with higher proportions of Black or Hisp...
A survey of Oregon's Medicaid and Medicare beneficiaries found that housing and food insecurity rose sharply during the pandemic, despite a significant increase in spending. The study suggests that addressing social needs during healthcare visits can improve health outcomes and reduce costs for taxpayers.
A study found that Oregon's COVID-19 stay-at-home order led to a significant increase in reported health-related social needs, including housing and food. The analysis suggests that public health interventions are needed to address these persistent needs.
A serial cross-sectional study found a significant decrease in positive reviews for health care facilities post-COVID, highlighting disparities in patient experience. The disparity is particularly pronounced in rural areas with high proportions of Black and white residents.
Life expectancy in the USA varies by more than 20 years depending on an individual's race and ethnicity and where they live. Researchers found that marginalized groups already had lower life expectancy, and the pandemic further increased the gap.
A recent study using regression discontinuity found that COVID-19 rates were higher among school-eligible children compared to those not eligible during in-person semesters. However, the difference decreased with each semester, and transmission was lower among school-eligible children during summer breaks.
A recent longitudinal study from the University of Toronto reveals that older adults with migraine are at a substantial increase in risk of depression during the pandemic. Increased family conflict, difficulties in accessing healthcare, and caregiving responsibilities were associated with higher risks of depression among this population.
A global team, including Lehigh University researcher Xuanhong Cheng, is exploring molecular- and cellular-level changes in muscle tissue that could lead to better diagnostic tools and therapeutic options for CFS and long COVID. The team aims to develop noninvasive diagnostic tools using electrical signatures.
Researchers have discovered that seemingly 'broken' genes in coronaviruses are retained due to their functional role beyond protein production. These extra genes help control the activity of other viral genes.
A Saint Louis University study found that COVID-19 stay-at-home orders facilitated easier breastfeeding, stronger mother-child bonding, and extended breastfeeding duration for many women. However, the pandemic also presented significant barriers, including limited access to lactation support and heightened maternal stress.
The study found that high oxygen therapy modalities increased oxidative stress and lung injury in patients with severe COVID-19 pneumonia. Patients who died of COVID-19 had significantly higher mean MDA levels than those who survived.
Researchers at Tokyo University of Science have successfully captured viral infection process under a light microscope using the giant Mimivirus. The footage showcases the proliferation of the virus and its release from cells, highlighting its biological significance in ecosystems.
The Portland State report highlights the positive impact of Project Turnkey shelters, which provide a sense of community and stability for residents. By offering private rooms, food, and hygiene supplies, as well as on-site case management, these sites help guests begin to imagine their future and make plans for stable housing.
A clinical study found that an FasL inhibitor, asunercept, led to a faster recovery of COVID-19 patients in eight days compared to 13 days in the control group. The treatment also reduced mortality by about 20%. The study suggests a new therapeutic concept for severe COVID-19.
A cross-sectional study found a low frequency of physician disciplinary actions for spreading misinformation, despite increased salience and warnings since the COVID-19 pandemic. The findings suggest a disconnect between regulatory guidance and enforcement, questioning the suitability of licensure regulation in combating misinformation.
A groundbreaking metagenomic sequencing test has proven effective in rapidly diagnosing almost any kind of pathogen, including viruses, bacteria, fungus or parasite. The test analyzes all nucleic acids present in a sample, replacing multiple tests with a single one and speeding up diagnosis.
A multidrug-resistant strain of Klebsiella pneumoniae has been detected in Northeast Brazil, with the bacterium being resistant to all available antibiotics. The strain had previously been detected in the US and can potentially spread globally.
A new study published in JAMA Network Open found that brief cognitive behavioral therapy via video telehealth reduces suicide attempts and suicidal ideation, providing critical insight into treatment options for those struggling with suicidal thoughts. The study also shows that this therapy is effective in reducing depressive symptoms.
A new study by Richard S. Saver found that medical boards rarely take disciplinary action against physicians for spreading misinformation, accounting for just 0.1% of all disciplinary offenses.
A study analyzing data from over half a million adults found lower survival rates for out-of-hospital cardiac arrests in predominantly Black and Hispanic communities, with improvements seen since the pandemic waned but not yet reaching pre-pandemic levels
A study found that heavy drinking among adult Americans increased by more than 20% during the COVID-19 pandemic and continued for the following two years. The study analyzed data from over 24,000 adults and showed a sustained increase in alcohol use across all age groups, genders, and regions.
A population-based study found that alcohol use increased during the COVID-19 pandemic and was sustained post-pandemic. Stress from the pandemic and disrupted access to medical services were identified as potential causes.
Cardiovascular disease death rates increased by 21% for adults aged 25-64 living in rural areas, while urban adults saw a 9% decline between 2010 and 2022. Younger rural adults are particularly vulnerable to cardiovascular mortality due to worsening cardiometabolic health and reduced healthcare access.
A new study analyzed how seasonal flu viruses moved and evolved during the COVID-19 pandemic, finding that they remained in certain regions despite reduced global mobility. The study suggests increased genomic surveillance capacity will help monitor seasonal influenza to reduce vaccine mismatches and inform effective interventions.
A longitudinal cohort study found no significant associations between prenatal SARS-CoV-2 infection and child neurodevelopment outcomes in the first two years of life. Follow-up research is needed to determine if these effects persist into later childhood.
Research highlights correlation between preeclampsia and COVID-19 in pregnant women, identifying biomarkers for differential diagnosis. The review article emphasizes the pathophysiological similarities between the two conditions, including shared pathways involving the renin-angiotensin system and ACE2.
The COVID-19 pandemic triggers a significant increase in pediatric mental health challenges, with rising rates of anxiety, depression, OCD, and suicidality. Theoretical models such as intolerance of uncertainty offer valuable insights into the mechanisms behind these increases.
A retrospective cohort study found associations between COVID-19 and the long-term risk of various autoimmune and autoinflammatory connective tissue disorders. Long-term monitoring and care are crucial to mitigate these risks, taking into account demographic factors, disease severity, and vaccination status.
A randomized clinical trial found that simultaneous administration of mRNA COVID-19 and inactivated influenza vaccines had comparable reactogenicity to sequential administration. This suggests a safe option for co-administration of these vaccines.
Researchers developed a new diagnostic tool called FlowBEAT to measure antibodies in nasal cavities, finding that more than 70% of people with mild or moderate COVID-19 develop protective autoantibodies in the nose. These autoantibodies may play a role in regulating the immune system and preventing excessive inflammation.
Researchers at Kumamoto University have developed a cutting-edge diagnostic tool, Intelli-OVI, to rapidly identify emerging SARS-CoV-2 variants. This system combines advanced DNA detection technology with computational algorithms to offer a quicker and more cost-effective method of monitoring viral mutations.
A cohort study found that hospital COVID-19 burden was associated with an increased risk of in-hospital adverse effects among patients with and without COVID-19. The results highlight the importance of hospitals having greater resilience and surge capacity to prevent declines in patient safety during surges in demand.
A study by Uppsala University finds that childhood overweight is associated with socio-economic disadvantage, particularly in regions with high rates of single parenthood and low education levels. The prevalence of overweight among 4-year-olds has fallen to pre-pandemic levels, but regional disparities persist.
A new study found a 29% increase in risk for developing dyslipidemia due to COVID-19, with seniors and people with type 2 diabetes being most affected. The research suggests that tackling dyslipidemia can reduce the risk of cardiovascular disease in those who have had COVID.
A recent study found that the pandemic led to a significant shift towards staying at home, with people spending nearly an hour less per day on out-of-home activities. The trend has continued post-pandemic, with time spent away from home still lower than in 2019.
A study by the American Psychological Association found that families who ate together more often during the pandemic had more positive interactions, shared news, and even used videoconferencing to connect with distant family members. This increased frequency was linked to improved quality of family time.
A new study found that the COVID-19 pandemic significantly increased rates of falls, bloodstream infections, urinary tract infections, pressure injuries, and pneumonia in U.S. hospitals. The study highlights the need to address ongoing challenges faced by nurses and invest in supporting them to provide high-quality care.