A recent study identifies 11 natural compounds that can inhibit the SARS-CoV-2 spike protein, including caffeine, which exhibits high binding stability and excellent solubility. The discovery highlights the potential of natural products in combating COVID-19 and demonstrates the versatility of widely known compounds like caffeine.
A new article from the NYC Preparedness & Recovery Institute assesses the city's response to the pandemic, highlighting key findings on mutual aid networks and their role in emergency response. The study identifies strategies to strengthen emergency preparedness moving forward.
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A recent Canadian Medical Association Journal study found no differences in in-hospital deaths or hospital admission rates between people experiencing homelessness and housed patients with severe COVID-19. However, those experiencing homelessness were less likely to be admitted to the intensive care unit or intubated.
The article explores how gentrification, economic processes, and urban capitalism lead to the decline of vibrant nightlife in cities like Helsinki. Researchers argue that DIY electronic music events and alternative practices can offer a solution to preserve nightlife.
A new analysis of NHS England survey data found that nearly one in ten people (9.1%) in England think they could have Long Covid but aren't sure. Higher rates were observed among people living in deprived areas, those with particular ethnic backgrounds, and parents or carers.
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Researchers found that women who became pregnant after the start of the pandemic were more likely to experience preterm birth and low birth weight, regardless of COVID-19 infection severity. Moderate-to-severe infections during pregnancy also increased the risk of adverse outcomes.
The summit will highlight the latest research on coronavirus, plant-based protein, and probiotics, with a focus on their applications in clinical practice. Studies have found that COVID-19 affects the gut microbiome in children, while dietary protein like S100B may promote a healthy microbiome.
Researchers developed CeSPIACE, a 39-amino-acid peptide drug candidate that binds to the spike protein, blocking viral entry. It demonstrates strong binding to major SARS-CoV-2 variants and shows efficacy against multiple strains in vivo and in vitro experiments.
A new study of over 1,500 individuals in the US and Europe found that those prone to nostalgia have more close friends and work harder to maintain their relationships. Nostalgia is associated with a greater number of strong social ties and better overall health and wellbeing.
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A study published in The Lancet highlights disparities and obstacles faced by low- and middle-income countries in gaining recognition for their scientific contributions. Researchers propose increasing visibility of journals from low- and middle-income countries, reducing publication fees, and ensuring a fairer peer-review process to fo...
A new study reveals significant shifts in new physicians' perceptions of their jobs, financial incentives, and practice locations during the COVID-19 pandemic. The research highlights the need for urgent policy interventions to address rural physician shortages and improve compensation structures.
A major clinical trial has identified ensitrelvir as an effective medication to prevent symptomatic COVID-19 in people exposed within households. The trial showed a 67% reduction in risk of illness among participants taking the antiviral compared to those given a placebo.
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A new analysis reveals that no country is on track to meet all 17 UN Sustainable Development Goals by the target year of 2030. Machine-learning tools were applied to over 20 years' worth of data from 231 indicators and GDP data, highlighting complex linkages between goals.
A lack of access to dentists during the COVID-19 pandemic led to a surge in hospital visits for children's painful dental issues. Research found a 62% increase in emergency department visits from Medicaid-insured kids, with young children being seen twice as often.
Researchers at the University of Zurich found that Swiss women had more children at the beginning of the COVID-19 pandemic due to better work-life balance and reduced economic uncertainty. However, birth rates have since fallen back, with young people being cautious about having children during the pandemic.
A new study published in PLOS Medicine estimates that the COVID-19 pandemic cost Europe 16.8 million disability-free years of life between 2020 and 2022. The study found that more than half of these lost years would have been lived without disability, highlighting the pandemic's long-term impact on older populations.
A research study found significant associations between aircraft rescue and firefighting personnel's perceived risk factors of COVID-19 and their actual outcomes. Participants who reported being more susceptible to COVID-19 had a higher likelihood of infection, while those who perceived severity had a lower likelihood.
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A study found that socioeconomically disadvantaged patients used emergency departments less for non-avoidable visits, despite an overall rebound in ED use by 2022. This trend reverses pre-pandemic increases in ED utilization among Medicaid and dual-eligible patients.
The COVID-19 pandemic has been associated with negative developmental trends in kindergarteners, persisting beyond the pandemic's onset. The study highlights troubling trends in kindergarteners' development before and during the pandemic, underscoring the need for further research.
A new study from the Complexity Science Hub reveals that pre-existing emotions do not significantly impair our ability to distinguish between real and false news. Emotions triggered by news content play a pivotal role, eliciting more anger and less joy in response to false news headlines.
A study by Dr. Haruka Kato found that households with children during the COVID-19 pandemic prioritized migration destinations with favorable communities and strong community ties. Social interaction-related factors emerged as significant determinants of migration, contrasting with work, environment, and housing determinants.
New York City residents can now access behavioral health treatment services, including cognitive therapy and medication management, at Mount Sinai's Center for Stress, Resilience and Personal Growth. The center aims to help individuals strengthen resilience, improve well-being, and navigate life challenges with confidence.
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Research finds that microglial dysfunction, neurovascular inflammation, and focal neuropathologies are associated with systemic inflammation in COVID-19. The study suggests that targeted inhibition of these changes could help alleviate neurological symptoms.
Researchers at Stanford University have discovered a method to use two antibodies to effectively combat the constantly evolving virus, which could lead to longer-lasting treatments for COVID-19. The antibodies were shown to be effective against all SARS-CoV-2 variants in laboratory testing.
Breast and colorectal cancer screening rates have recovered from pandemic-related declines, surpassing pre-pandemic estimates. Cervical cancer screening rates remain below pre-pandemic levels, indicating a persistent trend of declining early-stage diagnoses.
Researchers developed an AI model that predicts ICU length of stay with high accuracy, while providing comprehensive explanations for patient outcomes. The model's predictions were found to be just as accurate as other XAI models, but its explanations were more detailed and useful for hospital staff.
Recent studies demonstrate that smartwatches can detect infections early through subtle physiological changes, prompting timely action to slow disease spread. By identifying infections sooner and reducing social contacts, wearable technology may help contain future outbreaks and prevent pandemics.
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A new Concordia study shows that consuming alcohol to cope with fears of anxiety was linked to unhealthy outcomes in young adults during the pandemic. Anxiety sensitivity, a fear of experiencing anxiety symptoms and negative health consequences, was also found to predict higher levels of drinking among young adults.
A breakthrough CRISPR-based test has been developed to diagnose Pneumocystis jirovecii pneumonia (PJP), a life-threatening fungal infection. The test detects RNA from live fungi in blood samples and throat swabs, providing a faster and more accurate diagnosis than current invasive bronchoscopy procedures.
Researchers developed a new vaccine platform that provides robust, long-lasting protection against multiple flu strains and COVID-19. The vaccine boasts 100% survival rates in vaccinated mice following challenge with either virus.
A recent study found that COVID-19 pandemic increased SNAP benefits reduced racial and ethnic disparities in food insecurity. However, non-SNAP participants experienced no decline in food insecurity, highlighting persistent gaps in nutrition support for this vulnerable population.
The study found that the prevalence of adults with diabetes did not significantly change between 2013 and 2023. However, glycemic control among those with diagnosed disease worsened, particularly among young adults. This trend is concerning due to its potential impact on lifetime risk of cardiovascular events.
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The University of Cambridge has launched an Engineered Pandemics Risk Management Programme to address the urgent challenge of managing future engineered pandemics. The programme aims to build a network of experts from academia, government, and industry to understand social and biological factors that drive engineered pandemic risks.
Negative mood and lack of social contact surprisingly reduced unhealthy eating, while 'unhealthy' food helped maintain positive emotions and reduce stress. The study highlights the complex interplay between affective and social factors influencing eating behaviors.
A study found that consumer confidence in organizations using health data responsibly remained unchanged from 2020 to 2022. However, there was an increase in polarization between liberal and conservative respondents, with liberals showing increased trust in the federal government's handling of digital health data.
A study published in Nature Cardiovascular Research identified distinct immune signatures in myocarditis caused by SARS-CoV-2 infection and mRNA vaccines compared to non-COVID-19 myocarditis. The findings suggest a stronger immune response in post-COVID-19 myocarditis, while the inflammation appeared milder in post-vaccination cases.
A recent study from the University of Kansas found that people tend to prefer AI chatbots when discussing sensitive or embarrassing topics like health information, due to their anonymity and nonjudgmental nature. However, when individuals are angry, they still prefer human interaction.
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A new study suggests that mRNA COVID-19 vaccination may protect against post-COVID condition symptoms in children. The findings support the benefits of vaccination beyond acute protection, encouraging increased pediatric uptake.
A cohort study found no increase in sudden cardiac arrest/sudden cardiac death among young competitive athletes in the US, contradicting reports that linked COVID-19 infection and vaccination to the risk. The study suggests that many athlete cases shown in social media videos occurred before the pandemic, not due to COVID-19.
A study by Syracuse University researchers found that optimism promotes healthier behaviors and better psychological well-being in the face of stressors like the pandemic. Individuals with higher optimism levels engaged in more physical activity, perceived greater social support, and were less stressed and lonely.
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New UCLA-led research finds that Paxlovid does not significantly reduce COVID-19 hospitalization and mortality among vaccinated older adults. The study suggests that Paxlovid's potential effect on COVID-19 hospitalization in vaccinated older adults is four times weaker than originally reported.
US outpatient prescriptions for ivermectin and hydroxychloroquine increased significantly during the COVID-19 pandemic, with usage being three times higher among adults aged 65 and older. The study's findings highlight the need for policy reforms to combat misinformation and mistrust in scientific institutions.
A new study reveals US hospital occupancy has surpassed pre-pandemic levels, driven mainly by a 16% reduction in staffed hospital beds. This could lead to a bed shortage as early as 2032, posing significant risks to patient safety and mortality rates.
Researchers have identified a new variant, clade 1b, of the mpox virus that has become more infectious and is spreading rapidly across borders. The study found that this variant primarily spreads through heterosexual contact in densely populated areas, with an estimated fatality rate of 3.4%.
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A new study from the University of East Anglia finds that European life expectancy has slowed down since 2011 due to factors such as poor diets, lack of physical activity, and obesity. The research suggests that prioritizing healthier lifestyles in younger years is crucial for extending old age.
Researchers at Salk Institute discover SSRIs like Prozac regulate immune response, preventing sepsis in mice. The findings suggest a potential new use for the popular drug, which could lead to life-saving treatments and enhanced global preparedness for pandemics.
Small increases were observed in childhood obesity rates and severe obesity among US adults between 2013 and 2023. The study found no significant changes in waist circumference or other obesity-related measures during this period.
A study on Nigerian healthcare workers found that excessive iron levels increased the risk of catching COVID-19, while moderate deficiency didn't offer protection. The research highlights an evolutionary tradeoff between iron's benefits for immune function and its potential risk to pathogens.
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Immunocompromised individuals require regular vaccine boosters to protect against severe infections and new variants, research shows. Boosters may need to be administered four or more times to offer adequate protection.
Researchers at Osaka University developed a new technique called single-cell suppressive profiling of regulatory T cells (scSPOT) that can pinpoint the effects of Tregs on all other immune cells. The study found that Tregs most strongly affect CD8-EM T cells, which play a key role in fighting cancer and infections.
Researchers found that pandemic puppies, bought during the COVID-19 pandemic, had a greater burden of dog ownership, with higher costs and emotional challenges. Owners who reported problem behaviors, such as separation anxiety or aggression, also experienced a greater burden.
A new research paper found that physical activity (PA) is associated with better sleep quality in older adults during social isolation. Reduced levels of PA had a negative association with the quality of sleep in four studies, while one study found improved sleep patterns among active individuals.
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Researchers at University of California, Merced are using wastewater-based epidemiology to track nicotine use in San Joaquin Valley communities. The project aims to determine trends and levels of nicotine use through chemicals in wastewater, providing valuable insights for public health agencies and tobacco-control researchers.
A new national study suggests that depression rates among older people in England remain slightly higher than pre-COVID, while overall happiness and life satisfaction have improved significantly since the pandemic. This finding highlights the need for policies addressing immediate and lingering effects of the pandemic on mental health.
A study of 9,387 nurses from 35 countries reveals widespread mental health challenges, including anxiety, depression, and burnout. Nurses experienced more symptoms at work than at home, with loss and public aggression posing significant threats to their mental health.
A new study by Ohio State University researchers found that older adults who couldn't cover unexpected expenses through credit cards were more likely to report high levels of loneliness. The study suggests that financial stress can lead to social isolation in this demographic, highlighting the need for financial and credit counseling.
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A new study by OSU researchers found that playful adults demonstrated greater optimism, engaged in creative problem solving, and infused quality into everyday activities during the pandemic. Regular playtime can help cultivate this resource for building resilience and maintaining well-being.
NUS Medicine has launched a new centre to bolster global pandemic preparedness and response to infectious disease emergencies. The Centre for Infectious Disease Emergency Response (CIDER) will serve as an education and operational hub for public health professionals, researchers, and policymakers.
During the COVID-19 pandemic, primary care practices in the US experienced declining access to care, while average practice capabilities improved. Integrated practice ownership and accountable care organization participation were associated with better access and capability scores.
The study found a notable drop in common ophthalmic procedures following the COVID-19 pandemic, especially laser peripheral iridotomy, which declined significantly in the hardest hit areas of the Northeast. Eye drug injections showed minimal changes during this time.