Articles tagged with Covid 19
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Researchers at the University of Pennsylvania designed a new recipe for mRNA vaccines by adding phenol groups, which reduce inflammation and improve vaccine effectiveness. The modified lipids improved vaccine performance in various diseases, including COVID-19, cancer, and genetic diseases, with enhanced efficacy and reduced side effects.
A retrospective cohort study found that COVID-19 booster vaccinations significantly protected against severe COVID-19, but uptake was low. Interventions are needed to increase COVID-19 vaccine uptake among high-risk populations with cancer.
A new study published in JAMA Oncology found that vaccinated cancer patients are at lower risk for hospitalization and severe illness from COVID-19. The research analyzed data on over 161,000 cancer patients treated during 2022 and 2023, showing a significant reduction in hospitalizations by 29%.
A recent study by NYU researchers found that student preferences for home-cooked meals and fast food, as well as concerns about meal health, are significant barriers to student participation in free school meals. The study suggests that making healthy meals more appealing and accessible can help increase student participation.
Long-haul COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome share similar pathophysiologies, including oxidative stress, autoantibodies, and impaired mitochondrial energy conversion. These conditions also exhibit neurodegenerative outcomes, such as fatigue, sleep disturbances, and increased risk of dementia.
This study found that Black and Hispanic children were disproportionately hospitalized for COVID-19 and experienced severe disease compared to white and Asian or Pacific Islander children. Children with underlying medical conditions from these groups also had a higher proportion of hospitalizations.
A new study found that obesity rates in Canada increased faster after the start of the COVID-19 pandemic, especially among younger adults and females. The prevalence of obesity measured by BMI rose at a greater rate during the 4 years following the pandemic's onset compared to the previous 11 years.
The BA.2.86 Omicron strain was found to have emerged with a high number of genetic mutations in its spike protein, but failed to become a dominant strain. Its sporadic global detection has raised questions about the possibility of laboratory involvement in its emergence.
Life expectancy in California remained lower in 2024 than in 2019, with COVID-19 accounting for a deficit of 12.8%. The gap between racial groups narrowed, but life expectancy in the Black population was still significantly lower than others.
A large study of Danish children found that COVID-19 mitigation policies affected BMI across all weight categories, not just those with obesity. The findings suggest that age and BMI class differences were present, warranting policies targeting all BMI groups in children.
Researchers found consistent evidence of reduced global atmospheric oxidation in 2020, driven by decreased nitrogen oxide emissions and extreme wildfires in the Southern Hemisphere. This decline had a significant impact on methane concentrations, contributing to one of the largest annual increases ever recorded.
A new study from Karolinska Institutet found that adults who have survived childhood cancer are 58% more likely to develop severe COVID-19 if they contract the virus. Despite having a lower risk of infection, childhood cancer survivors experienced more serious consequences when they did become ill.
Scientists at Rockefeller University discovered critical errors in a 2022 study on the NiRAN domain, a key enzyme region in SARS-CoV-2 viral replication. The team's findings could have sweeping implications for drug developers working to design antivirals based on flawed assumptions.
A recent study found that the COVID-19 pandemic significantly increased cases of depressive and anxiety disorders, malaria in young children, and stroke and heart disease in older adults. The researchers highlight the need to strengthen health systems and adopt syndemic-informed strategies for future public health emergencies.
A recent study found that pet owners who recently adopted pets often struggled to access veterinary care, particularly those working from home and having children. The researchers analyzed an online survey of 751 US residents and discovered that 20% of all pet owners faced difficulties accessing basic veterinary services.
Dr. Danielle Beckman's research uses animal models to understand how viruses like COVID-19 trigger neurological damage and accelerate Alzheimer's disease. Her work has established critical connections between viral infections and neurodegenerative processes.
A new study from the University of Kansas has identified a small protein domain called Mac1 as a critical target for inhibiting coronavirus replication. The research team developed molecules that bind to Mac1 and inhibit viral activity in cell cultures, providing potential antiviral therapies for future pandemics.
A cross-sectional study revealed racial disparities in COVID-19 treatment, with targeted interventions like expanding rapid test access and virtual care potentially improving equity. The findings suggest that encounter-level factors, such as differences in diagnostic test type and site of care, contribute to these inequities.
A national survey reveals nearly one-third of US adults would not or might not test for suspected COVID-19 due to lack of perceived value. This test hesitancy can delay oral antiviral initiation and potentially lead to missed opportunities to limit transmission.
The Families First Coronavirus Response Act led to a significant decrease in Medicaid health insurance loss. The study found that the Act reduced the risk of losing health insurance for individuals enrolled in the Medicaid program.
The American College of Chest Physicians (CHEST) has launched a critical care APP education and certification program, covering 11 topic areas including patient-centered care and pharmacology. The CCAPP Certification Exam is now available, with an August 5 deadline to apply for the 2025 exam.
Researchers found journalists' reliance on online resources increased significantly during COVID-19, exposing them to threats like trolling, cyber stalking, and fake news. The study suggests a need for more resources to help journalists build skills to mitigate online trauma.
A new study suggests that monitoring airborne fungal spore levels can predict short-term outbreaks of flu and COVID-19 infections. High levels of fungal spores were strongly linked to increases in flu and COVID-19 cases, particularly in the fall season.
This cross-sectional study reveals a substantial rise in alcohol-associated liver disease mortality, particularly among women and younger adults. The findings highlight the importance of targeted public health initiatives to address this growing health concern.
A new study reveals that the SARS-CoV-2 nucleocapsid protein can spread between cells, triggering an immune response that mistakenly targets healthy cells. The researchers found that a commonly used anticoagulant, enoxaparin, can block this harmful interaction, potentially offering a new avenue for treatment.
A new study found that people with COVID-like symptoms took up to nine months post-infection to regain mental well-being, but physical well-being returned after three months. Up to 20% of patients continued experiencing suboptimal overall health-related quality of life one year after infection.
Researchers discover iguratimod, a rheumatoid arthritis drug, effectively treats excessive COVID-19 inflammation in mice by maintaining antiviral immune responses. The study provides hope for patients with severe COVID-19-related cytokine storms.
Researchers analyzed COVID-19 mortality among 5,813 patients in five Catalan hospitals. Patients without a ceiling of care had higher mortality during the first wave, but this decreased significantly over subsequent waves.
A new technology using microscopic beads marked with stable isotopes enables the simultaneous detection of dozens of different antibodies in hundreds of samples. This expands the capacity of serological analysis for biomedical research, vaccine development, and epidemiological studies.
The health care workforce experienced decreased employment growth during the pandemic but fully recovered by 2024. This unique recovery is attributed to health care financing via insurance coverage that shielded health care employment from macroeconomic fluctuations.
Researchers have identified a critical step in SARS-CoV-2 viral infection: the protective role of ORF3a, which forms dense bodies surrounding the spike protein to prevent it from being cut into smaller components. This finding could lead to new therapeutic targets and vaccine development strategies.
A cohort study of schools found that COVID-19-related decline in youth physical fitness persisted during the pandemic, but not associated with remote or hybrid environments. The reduction was observed in cardiorespiratory and musculoskeletal fitness healthy zone achievement.
A nationwide decline in MMR vaccination rates among US children was confirmed by a new dataset, with significant variations observed across states and counties. The study provides valuable insights into factors influencing low vaccination rates and can inform targeted strategies to reduce measles outbreaks.
Researchers at NYU Abu Dhabi have developed a breakthrough paper-based diagnostic device that can detect COVID-19 and other infectious diseases in under 10 minutes. The Radially Compartmentalized Paper Chip (RCP-Chip) is a fast, affordable, and portable solution for on-site screening of infectious diseases.
Researchers found cardiac deaths exceeded expected levels between 2020 and 2023, with a significant increase in 2020 and 2021. The study suggests potential shortcomings in cardiac care during and after the pandemic.
Researchers analyzed trends in healthcare utilization among Japan's oldest-old population aged 75 years and above during the extended COVID-19 pandemic. The analysis revealed a modest drop in medical services and outpatient visits, while healthcare costs remained stable despite decreased patient volumes.
Researchers identified unique symptom patterns and derived research indices for infants/toddlers and preschool-aged children, highlighting the need to characterize long COVID separately across age groups. The study provides new insights into the condition's progression in early childhood.
Researchers identify epipharynx as a key site for chronic inflammation driven by residual SARS-CoV-2 RNA in patients with long COVID. A novel treatment, epipharyngeal abrasive therapy (EAT), promotes removal of damaged tissue and immune modulation.
A new study published in JAMA Internal Medicine reveals a concerning decline in self-reported mental health among mothers in the US between 2016 and 2023. The percentage of mothers reporting excellent mental health dropped sharply from 38% to 26%, while those rating their mental health as fair or poor increased by 63.6%.
A study by researchers at the University of Arizona Health Sciences found that vaccinated people generated an overall protective immune response to Delta and Omicron strains, with slightly fewer antibodies for the mutated parts of the virus. The research suggests that immune changes due to antigenic imprinting may not be a significant ...
A new study led by Boston University School of Public Health reveals that US excess deaths have been increasing for decades, with working-age adults disproportionately affected. The study found that over 1.5 million 'missing Americans' would have been averted if the US had mortality rates similar to other high-income countries.
The study analyzed 14.7 million excess US deaths from 1980 to 2023, finding that rates remained higher than pre-pandemic levels. Excess deaths during and after the pandemic were largely driven by pre-existing causes such as drug overdose, firearm injury, and cardiometabolic disease.
A recent study published in Medicina found a significant increase in the number of young patients with anorexia nervosa in Japan following the COVID-19 pandemic. The researchers analyzed large-scale clinical data and discovered that the incidence of this eating disorder rose sharply during this period.
A study found that adults hospitalized for RSV had significantly higher odds of cardiac events compared to those with COVID-19 or influenza. The findings suggest that preexisting cardiovascular risk patients should consider vaccination against respiratory viral infections.
A large-scale genetic study identified the FOXP4 gene as a significant factor in Long COVID, linked to lung health and immune response. The study found a strong relationship between severe COVID-19 cases and Long COVID, highlighting potential biological factors contributing to the condition.
CoVFit integrates molecular data with large-scale epidemiological data to predict the fitness of SARS-CoV-2 variants. The model was trained on mutations in the spike protein and population-level trends, enabling accurate predictions of variant fitness.
An international team of researchers has identified a genetic link to long-term symptoms after COVID-19, with a gene variant increasing the risk by about 60%. The variant is located near the FOXP4 gene, which affects lung function and development. Impaired lung function plays a key role in developing long COVID.
A new study by University of Illinois researchers highlights the need for flexible approaches to reach diverse audiences with disease prevention strategies. The findings underscore that there is no one-size-fits-all solution to public health challenges, and understanding people's value systems can help inform policy recommendations.
A large cohort study found that early antibiotic treatment did not significantly improve outcomes for patients with nonsevere COVID-19. The results argue against routine antibiotic use in this population due to associated risks.
Researchers found that infants with severe COVID-19 have distinct immune responses, including high levels of interferon and inflammatory cytokines. This unique response may help protect or contribute to the severity of the disease, requiring further studies.
A national study in Sweden reveals that COVID-19 vaccination levels among older people have become increasingly uneven, with regional and socio-economic differences emerging. The study found lower vaccination rates among certain groups, including those born outside Sweden, men, and individuals with low income and education.
The UK's failure to focus on COVID-19 suppression led to thousands of avoidable deaths, according to an expert. By following the World Health Organization's advice and East Asian countries' strategies, the UK might have prevented up to 180,000 deaths.
A new AI model, EVE-Vax, uses evolutionary data to predict viral proteins and design future-proof vaccines against rapidly mutating viruses like SARS-CoV-2. By analyzing millions of years of genetic information, the model can create brand-new proteins with the same immune response as real viruses.
A meta-analysis of over 140,000 participants found a significant association between excess weight and neurological/neuropsychiatric symptoms in post-COVID-19 condition. The study suggests that maintaining a healthy weight may be crucial in mitigating these symptoms.
A study found that losing a parent increases the risk of bullying among female children, adolescents, and those in rural areas. The researchers hope this data informs tailored support for bereaved youth. Effective interventions should address emotional and social dimensions of support, fostering inclusive environments.
A new study uses foot traffic data to enhance neighborhood-level COVID-19 forecasts in New York City. The research reveals how routine activities like dining out and shopping became major transmission pathways, enabling the development of a behavior-driven model that outperforms traditional forecasting methods.
A recent study by Edith Cowan University has found a significant association between excess weight and long-term neurological and mental health symptoms after COVID-19. The researchers suggest that this link could be due to an exaggerated inflammatory response linked to fat tissue, which may store the virus and increase its spread.
Researchers found persistent inflammation in heart and lungs of patients with long COVID, even after standard tests return normal results. This study uses advanced PET/MRI imaging to detect abnormal patterns that could serve as early warning signs of future cardiac and pulmonary conditions.
Researchers have discovered that silver nanoparticles produced by the fungus Trichoderma reesei can inhibit the infection of SARS-CoV-2 in hamster lungs, reducing inflammation and viral load. The study also suggests that these nanoparticles could be used to prevent and treat other viral diseases, such as HIV/AIDS, shingles, and influenza.
A groundbreaking study from the University of Virginia Health System reveals distinct immune patterns in patients with persistent breathing issues after COVID-19. The research identifies specific T cell changes linked to lung damage and fibrosis, paving the way for personalized treatments.