Articles tagged with Gastrointestinal Disorders
A prospective study reveals coeliac disease patients experience a substantial excess of deaths, particularly within the first three years after diagnosis and those with malabsorption symptoms. Early diagnosis is crucial to prevent mortality, as delay in diagnosis and poor treatment adherence can significantly worsen outcomes.
A new study establishes a link between gastroesophageal reflux and allergies, including environmental allergens like pollens and molds. The discovery could lead to new treatments for children with eosinophilic esophagitis and adults with refractory reflux.
Researchers at Vanderbilt University Medical Center have identified a new drug therapy that appears to be effective in reversing symptoms of Ménétrier's disease, a rare and premalignant stomach disorder. The treatment, which blocks activation of the EGF receptor, showed promising results in a patient with severe vomiting and protein loss.
A new study reveals that free radicals, generated by the macrophage enzyme NADPH oxidase, are essential for the development of alcoholic liver disease. The researchers found that mice lacking this enzyme were resistant to liver injury and had lower levels of covalent adducts in their bile.
A study published in the New England Journal of Medicine highlights a rare genetic disorder Ehlers-Danlos syndrome Type IV, which increases the chance of early death. The disease affects between one in 100,000 and one in 500,000 people, with most deaths following rupture of large arteries.
Researchers at Thomas Jefferson University have developed a blood test to detect the spread of colorectal cancer to lymph nodes by identifying the presence of a protein called GCC. This test may help doctors diagnose the disease more accurately and provide better treatment options for patients.
Scientists have identified TNF-alpha as a major contributor to early liver injury from long-term alcohol consumption, paving the way for new treatments. The study used gene knockout technology and found that mice lacking TNF receptors fared better on measures of liver injury after alcohol exposure.
A mutated tumor suppressor gene has been identified as the cause of familial juvenile polyposis, a disorder affecting about 1 in 100,000 people. The discovery may provide insights into colorectal cancer diagnosis and treatment.