Headaches

Ultrasound has potential to alter how the brain responds to pain

TBI survivors turn to psychedelics for symptom relief

A new study found that nearly 1,200 TBI respondents used psychedelics to treat or manage physical health conditions, with 208 participants using them to manage brain injury-related symptoms. Researchers reported a 90% self-reported symptom improvement rate.

University of Calgary-led study shows link between migraine genetics and post-concussion headaches in kids

A University of Calgary-led study found that children with genes predisposing to migraine are at higher risk of developing more severe headaches after a concussion. The research identified specific genetic mutations and family history of migraine as associated risks.

Why does chronic back pain make everyday sounds feel harsher? Brain imaging study points to a treatable cause

A new study from CU Anschutz links chronic back pain to heightened brain responses to everyday sounds and finds that Pain Reprocessing Therapy can improve sensory amplification. The research found specific brain changes associated with sound hypersensitivity, which can be treated with psychological therapy.

Study suggests migraine may be overlooked in women with enlarged breast tissue

A small observational study found that most women with macromastia who experienced frequent headaches screened positive for migraine rather than tension-type headache. After surgery, participants reported fewer and less severe headaches, with improvements lasting over a year.

Complex Regional Pain Syndrome triggers migraines in majority of patients

A new study from Murdoch University found that 66% of participants with Complex Regional Pain Syndrome (CRPS) experienced migraines that started or worsened after CRPS onset. This research highlights the connection between CRPS and migraine, suggesting a possible common cause for both conditions.

Health issues linked to cosmetic jab complications

A study by Anglia Ruskin University found that patients with underlying conditions such as type 1 diabetes are at a significantly higher risk of complications from cosmetic botulinum toxin injections. The researchers recommend restricting administration to medically qualified professionals.

Combined oral contraceptive use among people with migraine with aura persists, despite cautions

A new study found that a sizable minority of people with migraine with aura still receive estrogen-containing birth control pills and hormone therapy, despite treatment contraindications. The study highlights the need for updated research on stroke risks associated with these medications among people with this type of migraine.

Barrow Neurological Institute, University of Calgary study urges “major change” to migraine treatment in Emergency Departments

A new study by Barrow Neurological Institute and the University of Calgary recommends greater occipital nerve blocks and elevating intravenous prochlorperazine to offer effective and safe treatment for migraine attacks. The guidelines aim to reduce opioid reliance and improve patient outcomes in Emergency Departments.

Low-glutamate diet linked to brain changes and migraine relief in veterans with Gulf War Illness

A new study found that a low-glutamate diet significantly improved migraine symptoms in veterans with Gulf War Illness, with measurable brain changes detected. Cortical thickness decreased in patients on the diet, suggesting a potential treatment for chronic neurological symptoms.

Headache disorders affect 3 billion people worldwide—nearly one in every three people, ranking sixth for health loss in 2023

Headache disorders affect nearly one in every three people, causing significant disability and health loss. Migraine and medication overuse drive most of the global burden, emphasizing the need for improved prevention, management, and access to care.

New study links teen migraines to hypertension: Why early blood pressure screening matters

A nationwide study from the Hebrew University of Jerusalem found that adolescents with migraines are three times more likely to have high blood pressure. The research suggests that early blood pressure screening for teens with migraines could help detect cardiovascular risks before they develop into chronic disease.

Open-label placebos as adjunct for the preventive treatment of migraine

An open-label placebo treatment was associated with improved quality of life and reduced pain-related disability in patients with migraine. However, the treatment did not reduce headache frequency in this study.

Job changes may cause headaches and insomnia

A nationwide survey of 20,000 people found that those who changed jobs in the past year reported higher rates of health symptoms. Job changers often experience more stress factors, such as late-night shifts and excessive workloads, which can negatively impact mental and physical health.

Despite increase in U.S. cases, worry about West Nile virus remains low

Despite an increase in US cases, worry about West Nile virus remains low, with only 15% of respondents concerned about contracting the disease. The vast majority know the best defense is preventing mosquito bites and controlling mosquitoes around their homes.

In quest for better NSAIDs, researchers decouple inflammation from pain

Scientists at NYU Pain Research Center identified the EP2 receptor as the main cause of inflammatory pain but not inflammation. Blocking this receptor silenced pain responses without affecting inflammation, offering a new strategy for treating prostaglandin-mediated pain.

New research reveals why acute and chronic pain are so different – and what might make pain last

A study from The Hebrew University of Jerusalem found that the brain's braking system fails in chronic pain, leading to increased pain signals. This discovery opens the door to targeted therapies and may help prevent pain from becoming chronic.

Here’s why migraine symptoms are worse in patients who get little sleep

Researchers discovered that a lack of sleep affects how people with migraines process pain signals in the brain. This can lead to increased sensitivity and severity of migraine symptoms, highlighting the importance of adequate sleep for migraine management.

Why paracetamol works: New discovery ends longstanding mystery

A new study reveals that paracetamol blocks pain signals before they reach the brain by acting on nerve endings. This discovery opens the door to developing safer pain treatments. The active metabolite AM404 targets specific sodium channels in pain-sensing neurons, stopping pain signals.

New insights into migraine-related light sensitivity

Scientists have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia) during migraines. By disrupting the normal balance of nerve signaling and pain regulation, NEAT1 makes nerves more sensitive to light.

How serious is your brain injury? New criteria will reveal more

A new framework for assessing traumatic brain injuries (TBI) will provide more accurate diagnoses and treatments, leading to better patient outcomes. The framework incorporates clinical symptoms, biomarkers, imaging scans, and modifiers to determine the severity of injury and predict recovery.

New ACP guideline recommends combination therapy for acute episodic migraines

The American College of Physicians (ACP) has developed new recommendations for the treatment of acute episodic migraines in nonpregnant adults. The guideline prioritizes the use of combination therapy, including a triptan with an NSAID or acetaminophen, to reduce harms and improve outcomes. Migraine remains underdiagnosed and undertrea...

Researchers receive $2.17 million grant to study noninvasive treatment for traumatic brain injury symptoms

Virginia Tech researchers Pamela VandeVord and Gunnar Brolinson received a $2.17 million grant to investigate cranial osteopathic manual manipulation as a potential treatment for traumatic brain injury symptoms, particularly headaches. The noninvasive technique aims to enhance brain fluid motion and balance the autonomic nervous system.

Surgery may improve memory and psychological health for Chiari malformation patients, Pitt and UPMC surgeons report

A study published in the Journal of Neurosurgery found that surgery can alleviate psychiatric distress and improve cognitive function in patients with Chiari Malformation type 1. Nearly 90% of patients showed improvements in cognitive function or psychiatric symptoms, with many reporting a significant reduction in brain fog.

Risk of attempted and completed suicide in persons diagnosed with headache

A cohort study reveals a robust association between headache diagnoses and suicidal behavior, highlighting the importance of behavioral health evaluation and treatment for these patients. The findings suggest that patients with headache diagnoses should be screened for suicidal ideation and provided with appropriate support.

University Hospitals Connor Whole Health study finds spinal manipulative therapy benefits patients with tension-type headaches

A retrospective study of over 6,200 patients found that spinal manipulative therapy significantly reduced the need for butalbital prescriptions and medication overuse headache. Patients receiving SMT were also less likely to develop MOH, with only 1.7% prescribed butalbital compared to 3.8% in non-SMT groups.

Early treatment for nerve tumors prevents serious problems, study finds

Researchers found that non-invasive stereotactic radiosurgery significantly improves tumor control and reduces symptoms such as tinnitus, cranial nerve deterioration, and vestibular dysfunction. Early treatment can prevent tumors from growing over time and spare patients from irreversible problems.

Burning incense can pose health risks for those with allergies and asthma

Prolonged exposure to incense smoke can cause headaches, respiratory dysfunction, dermatologic sensitivity, and allergic reactions in individuals with pre-existing conditions like asthma. Switching to electric or aromatic vapors, improved ventilation, and limiting burn time may help mitigate these risks.

Pain identified as dominant symptom in long Covid

A new study published in JRSM Open found that pain is the most prevalent and severe symptom reported by individuals with long Covid, affecting 26.5% of participants. Demographic factors such as age, gender, ethnicity, education level, and socioeconomic status significantly impact symptom severity.

Declining iron levels in women in the military

A recent study published in BMJ Military Health found that female conscripts' iron deficiency more than doubled from 25% to 55% after five months of basic military training. The study also showed a significant decrease in ferritin levels, which can lead to anemia and fatigue.

Feeling rough after your COVID shot? Congrats, it’s working!

A new study led by UCSF found that COVID-19 vaccine side effects like headache and tiredness indicate a strong immune response. Those with more symptoms had nearly double the antibody levels of those without, suggesting the vaccine is effective in preventing infection.

Migraine surgery reduces headache days, reports Plastic and Reconstructive Surgery

A study published in Plastic and Reconstructive Surgery reports that nerve decompression surgery effectively reduces monthly migraine days and improves other headache outcomes, including frequency and intensity of attacks. The findings provide strong evidence in support of headache surgery efficacy.

Pharmacists prove effective, less costly care option for minor illnesses

A study by Washington State University found that treating minor illnesses at pharmacies can be effective and cost-saving, with patients recovering from almost all their ailments after a single visit. The research suggests expanding pharmacists' clinical services could improve healthcare access and reduce costs.

Many children with symptoms of brain injuries and concussions are missing out on vital checks, national US study finds

A national US study found that nearly a quarter of children with symptoms of brain injuries or concussions were not checked for the condition. Younger children were more likely to be overlooked. Routine checks can help ensure these children receive necessary care and support their mental and social well-being.

Blood protein could help detect delayed concussion recovery in children

Researchers have discovered a blood protein that may aid in detecting delayed concussion recovery in children, with lower levels of alpha-1-antichymotrypsin (alpha-1-ACT) associated with prolonged symptoms. The finding holds promise for early detection and targeted treatment of long-term concussion problems.

Chinese Neurological Journal delves into optimizing chronic subdural hematoma treatment

Researchers from China conducted a nationwide study to assess optimal treatment strategies for CSDH. The study found that multimodality management and personalized treatment plans significantly reduced recurrence rates.

Poor sleep linked to migraine attacks in new UArizona Health Sciences study

A new study by UArizona Health Sciences researchers found that sleep disturbances increase the vulnerability to migraine attacks. Improving sleep health may decrease the likelihood of migraine attacks in people with migraine. The study used preclinical mouse models and found no link between migraine-like pain and disrupted sleep.

Blood flow changes in the eyes could influence visual symptoms of migraines

Researchers used OCTA to visualize retinal blood vessel changes in migraine patients during and between attacks. Blood flow decreases were found, with asymmetrical flow correlated to headache pain side.

Texas lab unlocks keys to alcohol withdrawal headache

A study by University of Texas Health Science Center at San Antonio researchers found that corticotropin-releasing factor (CRF) activates immune cells in the dura membrane under the skull, leading to pain signals. This discovery may lead to the development of a small-molecule drug therapy to inhibit CRF and MrgprB2 interaction.

Bullying, suicidal thoughts linked to more frequent headaches in teens

A recent study published in Neurology found an association between bullying and suicidal thoughts with more frequent headaches in teenagers. The research, which analyzed over 2.2 million teen participants, revealed that those who experienced bullying or suicidal tendencies were nearly twice as likely to have frequent headaches.

Blood pressure drug could prevent posttraumatic headaches

A study found that prazosin reduced headache frequency and severity in veterans with posttraumatic headaches. Participants who received prazosin had significantly fewer headaches than those on placebo, with an average of six days of headaches per month compared to 12 days.

Wakefulness-promoting agents effective for excessive daytime sleepiness but patients may discontinue due to side effects

Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.

Vaccination halves risk of long COVID, largest study to date shows

The study found that vaccination significantly reduces the risk of long COVID, while factors such as being overweight, female, smoker, or over 40 increase the likelihood of developing the condition. Vaccination halves people's risk of developing long Covid

Debunking pain myths could help teens recover faster

A world-first study from the University of South Australia is providing valuable insights into how young people understand chronic pain, potentially helping thousands of sufferers to better manage their symptoms and long-term wellbeing. Researchers found that young people tend to make sense of chronic pain by explaining it as a softwar...

New drug to lower brain pressure could treat blinding IIH headaches, trial finds

A phase two trial found that exenatide significantly reduced brain pressure and monthly headaches in seven patients with Idiopathic Intercranial Hypertension (IIH). The study showed a rapid action of the drug, with results indicating significant reductions in brain pressure and headache days compared to the placebo arm.

Study finds ‘classic triad’ of meningitis symptoms rare in both children and adults

A study finds that the 'classic triad' of meningitis symptoms - fever, altered mental state, and neck stiffness - are rare in both children and adults. The research highlights the need to improve symptom questioning to reduce treatment delays and improve outcomes for patients with bacterial meningitis.

Loss of muscle mass in acute stage of COVID-19 is associated with persistent symptoms, study shows

A study by researchers in Brazil found that loss of muscle mass during COVID-19 hospitalization is associated with the development of persistent symptoms such as weakness, shortness of breath, and fatigue. The study also showed that patients who lost more muscle mass had higher healthcare costs six months after discharge.

Long COVID patients and those with other illnesses experience similar, negative lingering effects during the pandemic

Research suggests that long COVID patients share similar lingering negative effects on physical, mental, and social well-being with individuals who have other illnesses. The study found moderate-to-severe residual symptoms in 40% of COVID-positive participants and 54% of those who tested negative.

Overweight women most likely to suffer long Covid

A new study from the University of East Anglia found that overweight women are more likely to experience symptoms of long Covid. The research also shows that people with long Covid are much more likely to need additional and lasting NHS care than those who make a swift recovery.

Electroshock therapy more successful for depression than ketamine

A meta-analysis of six studies concludes that electroconvulsive therapy (ECT) is more effective than ketamine in quickly relieving major depression symptoms. The analysis, published in JAMA Psychiatry, found no significant differences in ECT's success rate across various age groups and geographic locations.

Simple 20-20-20 screen rule really does help with eye strain, research shows

A study by Aston University confirms that taking a break every 20 minutes to look away from screens for at least 20 seconds reduces digital eye strain symptoms. The research, involving 29 participants, showed a marked decrease in symptoms such as dryness, sensitivity, and discomfort after using the reminders.

Metabolic markers could give clues for brain hypertension

A new study identified distinct metabolic profiles in women with Idiopathic Intercranial Hypertension (IIH), a condition characterized by raised brain pressure. Weight loss programs showed positive effects on results, suggesting that metabolism plays a role in disease development.

Fatigue, headache among top lingering symptoms months after COVID

A study by Medical College of Georgia at Augusta University found that fatigue and headache were the most common lingering symptoms after COVID-19, reported by 68.5% and 66.5% of participants, respectively. Cognitive impairment, depression, and anxiety were also prevalent among participants.

People respond differently to psychedelic drugs — genetics could be the reason

Researchers found that genetic variations in the serotonin 5-HT2A receptor impact its interaction with psychedelic drugs. Seven variants uniquely altered the receptor's response to psilocin, LSD, 5-MeO-DMT, and mescaline.

New study shows an increased prevalence of headaches in adolescents during COVID-19 pandemic

A new study found that online lessons during the COVID-19 pandemic led to a worsening of headache symptoms or new onset headaches in over one-third of schoolchildren. The study also linked headaches to depression, anxiety, and decreased academic performance.

Women over 50 who snore face an elevated risk of sleep apnea

A new study from Tel Aviv University finds that women aged 55 and over who snore are at significant risk for sleep apnea, which can be fatal. The researchers warn that the phenomenon often occurs during sleep, causing women to be unaware of their condition.

The Lancet Respiratory Medicine: Two years after infection, half of people hospitalized with COVID-19 have at least one symptom, follow-up study suggests

A follow-up study published in The Lancet Respiratory Medicine found that half of people hospitalized with COVID-19 have at least one symptom two years after infection. Long COVID symptoms persist, affecting quality of life, mental health, and healthcare use.

Racial, ethnic disparities in pain treatment for obstetric patients

A study of 8,900 patients in New York State hospitals revealed racial and ethnic disparities in pain treatment for obstetric patients. Obstetric patients in minority groups were less likely to receive an epidural blood patch (EBP) for postdural puncture headache during delivery hospitalization.

Study explores perceptions of and preferences for complementary and integrative medicine options for chronic headache

Researchers found that veterans with chronic headache are interested in combining alternative therapies like acupuncture and massage with mainstream medicine. Healthcare providers support patient empowerment, but need education on the scientific evidence for alternative therapies.

Global estimates of headaches suggest disorder impacts over 50% of the population

A new review estimates that 52% of the global population experience a headache disorder each year, with significant variations in prevalence rates across different age groups and regions. The study also highlights differences in diagnostic methods and their impact on estimated rates.