Articles tagged with Heart Disease
Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue, a process known as cardiac fibrosis. The study's findings suggest that inhibiting the degradation of eicosanoids may be a promising approach to preventing or reversing cardiac fibrosis.
Researchers found that time-restricted eating synchronizes circadian rhythms across multiple systems in mice, activating genes involved in specific diseases like cancer. Nearly 40% of genes in the adrenal gland and pancreas were affected by time-restricted eating, offering guidance for managing diseases.
Researchers developed a new epigenetic biomarker, GrimAge version 2, which leverages two DNAm-based estimators of plasma proteins to predict mortality risk. The study found that GrimAge 2 outperforms existing clinical biomarkers in predicting mortality across multiple racial/ethnic groups and associations with age-related conditions.
Researchers found genetic mutations to OAS and RNase L proteins increase inflammatory response in immune cells, leading to MIS-C. This understanding may provide clues to chronic inflammation diseases like Kawasaki disease.
A Christmas-themed physical activity intervention during Advent showed promise for increasing physical activity and reducing sedentary time among inactive adults. The study, published in the BMJ, found that participants who received a daily email with physical activity ideas reported participating in more moderate-to-vigorous intensity...
Researchers at Cleveland Clinic found that elevated levels of phenylacetylglutamine, a byproduct of gut microbiome breakdown, increase heart failure risk and severity. This discovery suggests potential approaches to modify PAG-associated risks through diet and beta blocker use.
A recent study discovered a link between soluble urokinase plasminogen activator receptor (suPAR) and the development of atherosclerosis, a hardening of arteries that affects over a billion people worldwide. SuPAR was found to cause inflammation in blood vessels, leading to cardiovascular events and increasing risk of heart disease.
Researchers will investigate the relationship between heart function and aorta stiffness to identify risk factors for heart failure in Hispanics/Latinos, who are disproportionately affected by this condition. The study aims to develop new methods for predicting and preventing heart failure in underrepresented populations.
A study followed over 7,000 Canadians for three years to find that being female, physically active, and not obese were key to maintaining excellent health. Factors such as high income and social support also played a crucial role in optimal aging.
A recent study published in Nature Cardiovascular Research found a link between COVID-19 and postural orthostatic tachycardia syndrome (POTS), with patients infected five times more likely to develop the condition. Vaccination was also linked, but at a lower risk, emphasizing the importance of vaccination in reducing POTS.
A new study found that extreme temperatures are linked to a higher risk of cardiovascular death, particularly heart failure, which was the leading cause of death globally. The research analyzed data from 32 million cardiovascular deaths in 567 cities across 27 countries between 1979 and 2019.
A global analysis of over 32 million cardiovascular deaths found that extreme temperatures increase the risk of heart failure deaths. People with heart failure are most likely to be negatively impacted by very cold and very hot days.
As people age, their health care needs become more complex, making it essential to consider anatomical and functional changes when diagnosing and treating ACS. An individualized and patient-centered approach is best for older adults, considering coexisting conditions and input from multiple specialists.
People with rheumatoid arthritis have a higher risk of cardiovascular disease due to inflammation. However, new research suggests that commonly used treatments for RA can also lower this risk by reducing arterial inflammation and disease activity. The study found that immunomodulators like methotrexate and TNFi drugs reduced heart dise...
A Cedars-Sinai study found that even subtle forms of liver disease directly impact heart health, with elevated FIB-4 scores associated with abnormalities in heart function and vascular dimension. Cardiac MRI scans revealed that nearly 86% of patients had at least one heart abnormality.
A study published in the Hypertension journal suggests that bromocriptine, a Parkinson's disease medication, may help prevent heart disease in youth with Type 1 diabetes. The research found that teens with Type 1 diabetes who took bromocriptine had lower blood pressure and less stiff arteries after one month of treatment.
The American Heart Association has added a new $4 million grant to its $24 million Strategically-Focused Research Network (SFRN) on the Science of Diversity in Clinical Trials. The new center, led by researchers at Johns Hopkins University and Morgan State University, aims to identify ways to increase participation and recruitment of p...
Researchers at the University of Missouri are developing a wearable heart monitor using a breathable material with antibacterial and antiviral properties. The device will track heart health via dual signals, providing continuous monitoring for early detection of heart disease.
Researchers developed an app to track CPAP use, sleep patterns, and other health metrics to provide a new adherence metric that aligns therapy with individual need. This tool can help patients and providers deliver more effective sleep apnea treatment by tracking progress toward a personalized dose of therapy.
Researchers identified a genetic variant linked to digestive disturbances in patients with Chagas megaesophagus, a disorder characterized by esophageal dilation and loss of motility. The study suggests that increased interferon-gamma production leads to mitochondrial dysfunction, contributing to the development of the disease.
A study by Harvard Medical School found that women and men receive different advice on preventing heart disease, with women advised to lose weight, exercise, and improve their diet while men are prescribed statins. This discrepancy highlights the need for greater awareness among health professionals.
The prevalence of methamphetamine-associated heart failure is rising worldwide, affecting a wide range of socio-economic and racial groups. Meth users are more likely to develop severe disease, with longer hospital stays and readmissions, compared to non-users.
A new study published in the American Journal of Cardiology found that a healthy diet can reduce the risk of cardiovascular disease by up to 10%. The Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes whole grains, lean proteins, and fruits and vegetables, showed additional benefits for women and black adults compare...
A lower frequency of adding salt to foods is associated with a reduced risk of heart disease, regardless of lifestyle factors and pre-existing disease. Combining a DASH-style diet with low salt usage further improves heart health.
A recent clinical trial found that the Green Mediterranean diet reduced visceral adipose tissue by 14%, outperforming both the traditional Mediterranean diet and a healthy diet. The new diet incorporates dietary polyphenols and lower red meat intake, resulting in significant weight loss benefits.
A new study using artificial intelligence has found that a simple eye test can accurately predict the risk of heart disease. The researchers developed an algorithm that can analyze retinal images to assess cardiovascular health, providing a non-invasive alternative to traditional risk scores.
A UCF researcher is studying the potential long-term effects of COVID-19 on people with diabetes, including how it can advance their risk for heart disease and other complications. Dr. Singla believes that COVID-19 can alter a person's genetic makeup, leading to enhanced proliferation of disease.
Researchers at University Hospitals and Case Western Reserve University have discovered a small-molecule oral drug that reduces PCSK9 levels and lowers cholesterol by 70% in animal models. This breakthrough could also improve the efficacy of cancer immunotherapies.
A 30-year follow-up study of patients with early breast cancer found that radiotherapy does not improve overall survival rates after 10 years but reduces the risk of recurrence in the same breast. The study's findings challenge traditional concepts of long-term anti-cancer benefits of radiotherapy.
A new study from Mount Sinai Hospital finds a strong association between age-related macular degeneration and severe forms of heart disease, including heart failure, heart attacks, and stroke. The study highlights the importance of increased screening for eye disorders to diagnose undetected heart disease.
A new study found that long-term exposure to air pollution can increase the risk of high blood pressure and heart disease in teenagers. The review of eight studies involving over 15,000 adolescents aged 12 and above found a significant association between air pollution and rising diastolic blood pressure.
Researchers found that exposure to e-cigarettes, marijuana, and tobacco led to increased scarring, decreased blood vessels, and changes in heart nerves, all contributing to an increased risk of arrhythmias. These substances can cause similar harm to the heart as traditional cigarettes.
A study of 11,945 people found that those with type 2 diabetes are more likely to be diagnosed with advanced cancer if the condition is not screened for routinely. Researchers identified a 26% increased risk of metastasis in patients with pre-existing type 2 diabetes.
A large Nordic study found that children born to mothers with preeclampsia have higher risk of ischemic heart disease and stroke. The association holds even after accounting for other birth complications such as preterm birth and low birth weight.
A large study found that children who experienced adversity, including serious family illness or death, poverty, neglect, or dysfunctional relationships, are at increased risk of developing cardiovascular disease in early adulthood. The study, published in the European Heart Journal, followed nearly 1.3 million children and found a 60%...
Research at Tel Aviv University found that high-intensity aerobic exercise increases glucose consumption in internal organs, reducing energy availability for tumors. The study reduced the risk of metastatic cancer in humans and animal models by up to 72%.
Researchers at Mayo Clinic developed an AI algorithm that accurately detects weak heart pumps using single-lead Apple Watch ECGs. The system has shown promising results, rivaling medical treadmill diagnostic tests in accuracy, and holds potential for scalable screening and prevention of heart failure.
A Rutgers study of 86,964 adults with obesity and NAFLD found that bariatric surgery reduced the risk of major cardiovascular events by 49% compared to nonsurgical care. This is significant because heart disease is a leading cause of death in the US, and NAFLD can lead to liver damage and inflammation.
A new comprehensive guideline, C-CHANGE, offers 83 actionable recommendations to prevent and treat cardiovascular disease in Canadian adults. The updated resource incorporates new or revised recommendations from 11 guideline groups, addressing key risk factors such as dietary habits, smoking, and physical activity.
A recent study found that restoring blood flow to the legs through bypass surgery or stent placement reduced pain and improved quality of life for people with peripheral artery disease (PAD). The Best Endovascular versus Best Surgical Therapy for Patients with Chronic Limb Threatening Ischemia Trial enrolled 1,830 participants and foun...
Researchers found that two common diuretics, chlorthalidone and hydrochlorothiazide, had no difference in cardiovascular outcomes among study participants. However, those taking chlorthalidone showed a reduced risk of heart disease and death by an average of 27% among patients with a history of heart attack or stroke.
A study published in the American Heart Association found that six common dietary supplements did not lower LDL cholesterol levels when compared to a low-dose statin medication or placebo. The research suggests that these supplements are unlikely to offer meaningful impact on cholesterol levels, and a heart-healthy lifestyle is still t...
Researchers at Brigham and Women's Hospital found that olpasiran, a small interfering RNA drug, significantly reduces lipoprotein(a) levels in patients with established cardiovascular disease. The treatment was associated with minimal serious side effects apart from injection site reactions.
A study published in the Journal of the National Comprehensive Cancer Network found that breast cancer survivorship has doubled among Canadian women, with 2.1% of adult females diagnosed with breast cancer and 86% surviving by 2022. The prevalence varies by age group, with senior women having a higher rate of survival.
At AHA22, Smidt Heart Institute experts will cover various cardiology topics, including atrial fibrillation treatment and high-impact trials in intervention and surgery. Experts like Christine Albert, Joanna Chikwe, and Jon Kobashigawa will present their research on the effects of Omega-3 fatty acids and stroke management.
The new guideline covers key aspects of aortic disease diagnosis and management, including surgical intervention considerations, consistent imaging practices, genetic and familial screenings. The ACC and AHA emphasize the importance of a multidisciplinary team in providing optimal care for patients with aortic disease.
Researchers genetically modified mice to develop a similar disease to humans, identifying previously unknown mechanisms and potential therapeutic targets. The study found that reduced adhesion between cardiac muscle cells leads to scarring and arrhythmia, providing new insights into the disease.
A new study published in Journal of the American College of Cardiology found that drug-coated balloons outperformed bare metal stents in treating femoropopliteal lesions. The research showed improved 12-month patency and freedom from clinically driven reintervention and major adverse events with drug-coated balloons.
Researchers analyzed 30 years of cardiovascular mortality data from the US and UK, finding that lead exposure contributes more to CVD death risks in the US. The study also revealed a steady decline in cardiovascular deaths associated with all environmental factors in both countries.
A recent study published at the American Heart Association’s Scientific Sessions 2022 found that pod-based e-cigarette users experienced changes in blood vessel health comparable to traditional cigarette smokers. The research, which included 106 young adults without cardiovascular disease, measured vascular function, blood pressure, an...
A new daily anti-clotting pill, edoxaban, shows promise in preventing bleeding and clotting instances rare in children with heart conditions. The study's findings indicate edoxaban is a viable alternative to current treatments, eliminating injections and reducing frequent blood tests.
A recent analysis of COVID-19-positive donor heart transplants found no significant differences in transplant outcomes compared to those from non-COVID-19 donors. The study's results suggest that COVID-19-positive hearts may be as safe for transplantation, potentially addressing the shortage of available donor organs.
Researchers tracked participants for almost 30 years and found a link between past exposure to intimate partner violence and future cardiovascular health. The study suggests that intimate partner violence is associated with a higher risk of heart attacks, strokes, and heart failure hospitalizations.
A study found that living in a food desert increases the risk of heart attack, stroke, and early death for people with PAD. People with PAD living in food deserts were 17% more likely to experience a major cardiac event compared to those with better nutrition access.
Researchers found that marital stress among younger adults (ages 18–55 years) is associated with poorer recovery after a heart attack. The study of over 1,593 participants showed that higher levels of marital stress were linked to reduced physical and mental health outcomes.
Researchers found a longer PR interval and prolonged QT duration in genetically modified pig hearts after transplantation into humans, indicating signs of electrical disease. The study provides a foundation for future research to better understand xenotransplantation's effects on the heart's electrical system.
A study of 9,303 US adults found that people with cardiovascular disease were less likely to use wearable devices, highlighting disparities in access and use. The research emphasizes the need to ensure equitable access to wearables to benefit high-risk populations.
Researchers found a significant increase in heart disease deaths among adults in the US during the COVID-19 pandemic. The study attributed this rise to factors such as lockdowns, lack of physical activity, increased smoking and alcohol use.
Research published in European Heart Journal found that accumulating short bouts of vigorous activity across the week can help live longer. The study also showed that increasing intensity was associated with a reduced likelihood of cardiovascular disease.
A new type of pacemaker that uses precise targeting capabilities to bypass pain receptors and reduce patient discomfort is being developed. The device, which uses light and optogenetics, could improve the quality of life for millions of people affected by atrial fibrillation.