Articles tagged with Heart Disease
Dr. Bibbins-Domingo's research focuses on racial disparities in cardiovascular disease prevention, incidence, and outcomes. She explores long-term effects of early and poorly treated high blood pressure and develops strategies to prevent and manage CVD.
A novel screening tool has been developed to diagnose a serious heart condition in young athletes. The tool uses non-invasive ultrasound techniques to accurately identify cardiomyopathy, reducing false positives and providing better protection for the athletes of tomorrow.
A new study found that living in a community with easy access to grocery stores and affordable, healthy food is associated with lower heart failure death rates. The research analyzed data from nearly 3,000 counties in the US and found that food insecurity is linked to increased rates of death from heart failure.
The University of Missouri has earned an $8 million grant from the National Institutes of Health to expand its National Swine Resource and Research Center. The center will support research using genetically modified pigs to study human diseases, with a focus on therapies that can be translated from pig models to humans.
The study reveals that a genetic mutation can accelerate the body's internal clock, leading to improved adjustment to shift work schedules. The findings have implications for understanding the health consequences of circadian misalignment and developing medical treatments.
A genetic variant associated with low levels of HDL 'good' cholesterol and high triglycerides has been identified in Polynesian people. This discovery provides new insights into the genetic causes of high cholesterol and may lead to the development of more effective treatment options.
A recent NIH-supported study found that Black adults treated at advanced heart failure centers received potentially life-changing therapies, such as transplants and heart pumps, about half as often as white adults due to racial bias. The researchers also suggest that unconscious bias and overt racism may be driving these disparities.
Patients taking apixaban had a 43% lower risk of stroke or systemic embolism compared to those taking rivaroxaban. Apixaban also reduced the risk of bleeding events by 49% in patients with atrial fibrillation and valvular heart disease.
A new study found that sleeping five hours or less per night is associated with a higher risk of developing at least two chronic diseases over a 25-year period. This includes heart disease, cancer, and diabetes. The study analyzed data from over 7,000 men and women aged 50, 60, and 70.
Researchers have developed genetic testing to diagnose cardiomyopathy in children, identifying those at risk of heart failure and requiring a transplant. The test provides precise clinical diagnosis, enabling targeted treatment options and reducing the need for life-threatening interventions.
A recent study published in the Journal of Nutritional Science found that consuming potatoes has no increased risk of cardiometabolic disorders. In fact, those who ate more potatoes also consumed more fruits and vegetables, meeting dietary guidelines recommendations.
A UC Riverside-led study found that acute THS exposure initiates mechanisms of inflammatory skin disease and elevates urinary biomarkers of oxidative harm. The researchers discovered elevated molecular biomarkers in blood associated with early-stage activation of contact dermatitis, psoriasis, and other skin conditions.
Children with homozygous familial hypercholesterolemia are diagnosed earlier and have higher untreated LDL-C levels than adults, while those not identified early miss out on decades of life-saving treatment. This study emphasizes the need for universal screening to identify children with HoFH or heterozygous familial hypercholesterolemia.
Researchers found that metformin targeted 30 genes associated with atrial fibrillation, showing direct effects on gene expression for eight. The study suggests metformin may be a promising candidate for treating atrial fibrillation due to its potential to reduce the risk of complications such as stroke and heart failure.
Particle radioactivity from radon in air pollution increases toxicity and risk of death from cardiovascular disease, especially from heart attack and stroke. Researchers used spatiotemporal predictions to estimate exposure and found that higher gross beta-activity levels increased the risk of death from these conditions.
Researchers at FAU's Schmidt College of Medicine are developing a pilot program to tackle health disparities by leveraging electronic health records, artificial intelligence, and machine learning. The project aims to improve AI/ML delivery and research operations in community health centers and federally qualified health centers.
Scientists have identified long interspersed nuclear element-1 (L1) RNA as a promising new target for treating progeroid syndromes. Increased L1 RNA expression in cells from patients with these disorders led to deactivation of an enzyme, causing cell aging.
A randomized clinical trial found that time-restricted eating (TRE) is safe and feasible for 24-hour shift workers, improving glucose levels and blood pressure in those with cardiometabolic risk factors. Participants who followed a TRE pattern experienced improved quality of life and reduced bad cholesterol.
A randomized controlled trial found that combining time-restricted eating (TRE) and high-intensity interval training (HIIT) improved long-term glycemic control and reduced fat mass in women with overweight/obesity. The study also showed increased cardiorespiratory fitness.
A study from UniSA researchers found associations between metabolic profiles and adverse brain findings, including lower hippocampal and grey matter volumes. People with metabolic profiles linked to obesity were more likely to have higher accumulation of iron in the brain.
A recent study found that 38% of people with cardiovascular disease were food insecure in 2017-2018, more than doubling from two decades earlier. Food insecurity exacerbates existing racial and ethnic health disparities and can lead to increased risk for cardiometabolic risk factors.
The Leducq Foundation has awarded $7.5 million to UVA researchers, led by Mete Civelek, to investigate sex differences in atherosclerosis and $8 million to Coleen McNamara to advance immunotherapy for cardiovascular disease. These projects aim to improve understanding of heart disease and develop new treatments.
A new study found that only around half of older adults with hypertension regularly check their blood pressure at home. Those who received a healthcare provider's recommendation to do so were three and a half times more likely to monitor their blood pressure regularly.
Researchers at the University of East Anglia have developed a super-fast MRI scan that can diagnose patients with heart failure in record time. The new 4D heart MRI scan takes just eight minutes to produce detailed images of the heart valves and blood flow, helping doctors determine the best course of treatment.
A new study finds that consistently losing an hour and a half of sleep per night can negatively impact immune stem cells, leading to increased inflammation and cardiovascular disease. Even after catching up on sleep, the effects of disrupted sleep remain long-lasting.
A new study published in Current Opinion in Endocrinology, Diabetes and Obesity suggests that statin therapy is not justified for healthy individuals with high cholesterol. The research found a very weak association between low-density lipoprotein-cholesterol (LDL) and the risk of heart disease and stroke.
UC San Diego researchers created the first diagnostic tool to differentiate between Kawasaki Disease and Multisystem Inflammatory Syndrome in Children (MIS-C) using a novel artificial intelligence-guided algorithm. The algorithm achieved accuracy exceeding 90% with simple test results and physical exam features.
A randomized trial found that a 12-week online yoga program improved knee function in participants, but did not significantly reduce knee pain during walking. The study suggests that unsupervised online yoga programs can be feasible and improve physical function, but more research is needed to sustain the effectiveness.
A collaborative network led by Cincinnati Children's Hospital Medical Center has received an $8 million grant to identify and validate biomarkers for acute rheumatic fever. This will enable the development of a sensitive and specific diagnostic test, crucial for diagnosing rheumatic heart disease, which is caused by a slow but progress...
Researchers from the University of Copenhagen have identified a new mechanism in ARVC that could lead to a potential treatment strategy. They found that activating sirtuin-3 can slow down disease progression, and honokiol, a natural product extracted from the tulip tree, has been shown to work similarly.
A study using STS/ACC TVT Registry data found that most patients with severe mitral regurgitation (MR) and cardiogenic shock who underwent TEER achieved successful MR reduction, with associated lower mortality and heart failure hospitalizations at one year. Device success was linked to improved survival rates in a high-risk population.
A new study published in the Journal of the American Heart Association found that air pollution may trigger irregular heart rhythms in healthy teenagers, with exposure causing arrhythmias to occur within two hours. The research analyzed data from over 300 adolescents and found a significant impact of fine particulate matter on cardiac ...
Valentin Fuster, MD, PhD, is honored with the TCT Career Achievement Award for his transformative work in interventional cardiology and patient care. He has made significant global contributions to cardiovascular medicine.
New research estimates the overall disease burden of genetic risk factors on healthy life years lost, prioritizing interventions using genetic information. The study found that common genetic variants for cardio-vascular diseases and Alzheimer’s disease have a substantial population-level impact.
The University of Ottawa-led team aims to bridge the gap between heart and brain health by developing new diagnostic tools and treatments. They will focus on improving patient outcomes for disorders linked to both organs.
A new study published in leading journals found that achieving 10,000 steps a day can lower the risk of dementia, heart disease, cancer, and death. However, a faster stepping pace showed even greater health benefits, making walking faster a crucial factor for overall health.
A large international study of 156,000 people from 21 countries found that women have lower CVD risk than men, especially at younger ages. However, diet was more strongly associated with CVD risk in women than men, while high cholesterol and depression were more common risk factors for men.
Researchers found that high blood pressure induced in young mice led to significant bone loss and osteoporosis-related damage comparable to older mice. The study suggests a possible link between inflammation, high blood pressure, and accelerated bone aging in humans.
A large French study found a potential direct association between higher artificial sweetener consumption and increased cardiovascular disease risk. The researchers suggest that these food additives should not be considered a healthy alternative to sugar.
A new study led by a 16-year-old scientist found that certain ultra-processed foods, such as candy and pastries, can lead to increased consumption of other unhealthy foods among teenagers. Reducing consumption of these 'gateway' foods may help reduce overall unhealthy food intake and positively impact health.
A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.
A UBC Okanagan study found that commercial weight management programs are more effective than DIY approaches in helping people lose weight. Participants who used a commercially available program lost over twice as much weight and had better success rates, including improved blood pressure and waist circumference.
A new study from the Smidt Heart Institute shows that when height is accounted for, women are 50% more likely to develop atrial fibrillation (AFib) than men. The study's findings suggest that medical practitioners must remain vigilant in promoting AFib prevention and early interventions among both female and male patients.
A study of NASA astronauts found DNA mutations associated with spaceflight, increasing the risk of cardiovascular disease and blood cancer. Regular screening is recommended to monitor astronaut health.
A new clinical practice guideline provides guidance on delivering women-focused cardiac rehabilitation programs to increase participation and improve outcomes. The guideline presents 15 recommendations to address inequities in cardiovascular disease care for women.
Two large studies found a link between high consumption of ultra-processed foods and increased risks of cardiovascular disease, bowel cancer, and death. The findings support policies limiting ultra-processed foods and promote eating unprocessed or minimally-processed foods for improved public health.
Researchers developed a method to identify valve dysfunction using complex network analysis that is accurate, simple to use, and low-cost. The diagnostic tool works by analyzing the sounds produced by the heart, creating a graph of connected points, and identifying correlations between nodes.
A long-term study found that older homeless people are at a high risk of dying, with a median age of death of 64.6 years old. The study also found that people who first became homeless at age 50 or later were about 60 percent more likely to die than those who had become homeless earlier in life.
A clinical trial found that long-term use of evolocumab led to further reductions in cardiovascular events compared to shorter treatment. Participants who received evolocumab for over 5 years had lower risk of cardiovascular death, myocardial infarction, stroke, and hospitalization.
A Kaiser Permanente study found that patients in home-based cardiac rehabilitation had fewer hospitalizations than those in center-based rehab, with benefits seen across diverse patient populations. The home-based program improved accessibility and outcomes for high-risk patients.
Researchers at the University of Otago are closer to treating heart disease in people with type 2 diabetes. Their new treatment uses microRNA therapy to restore heart function and reduce cell death, showing promise for improving health outcomes.
Researchers from UMass Amherst have created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue. This breakthrough device has the potential to lead-edge applications in cardiac-disease experiments and improve health monitoring for cardiac disease studies.
The TCT MedTech Innovation Forum is an intensive summit bringing together clinicians, entrepreneurs, investors, and regulators to identify clinical challenges and drive innovation in medtech. The agenda features interdisciplinary perspectives on unmet clinical needs, financing, regulatory policy, and evolving healthcare delivery models.
A recent study published in JAMA found that despite overall improvements in cholesterol levels since 2008, sex, racial, and ethnic disparities persist in lipid control. The research team analyzed data from over 33,000 US adults and discovered significant variations in trends by race and ethnicity.
Researchers at RIKEN have discovered how marsupials' hearts can regenerate for several weeks after birth, allowing for potential treatment of human heart disease. They found that inhibiting a protein called AMPK extended the period of regeneration in both mice and opossums, with minimal scarring.
Using standing desks alongside other measures reduced office workers' sitting time by about an hour a day over one year, leading to small improvements in stress, well-being, and energy levels. A height-adjustable desk was three times more effective than the standard SWAL intervention in reducing sitting time.
A study by CNIC scientists has identified a key role for the MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy. Inhibition of p38α promotes an unexpected activation of the other branch of the pathway, consisting of the proteins MKK3, p38γ, and p38δ. This activation induces another key pathway in cardiac hypertrophy, the mTOR pathway.
A 1g reduction in daily salt intake could prevent nearly 9 million cases of heart disease and stroke in China by 2030, saving 4 million lives. This is based on a modelling study that estimates the impact of reducing salt intake across the nation.
A new gene variant, MFGE8, has been discovered that protects against coronary heart disease, with carriers experiencing a one-fifth lower risk. The variant is located in the MFGE8 gene and inhibits the function of lactadherin protein, which affects arterial stiffness.
Researchers from Boston Children's Hospital found that aging heart muscle cells accumulate new genetic mutations over time, but lose the ability to repair them. This accumulation of mutations can push the heart past a tipping point into disease.