Researchers found that a protein associated with reduced heart disease also protects against Alzheimer's-like brain damage in mice. Increasing levels of LDL receptor may slow or stop cognitive decline, offering a promising treatment strategy for dementia.
Researchers will examine regulation and disease relevance of alternative splicing in different types of heart cells. The project aims to map the path from splicing factor discovery to drug development.
Researchers found that mutations in cardiac myosin-binding protein C (cMyBP-C) cause HCM through unknown mechanisms, altering protein integrity or mechanical properties. This knowledge is crucial for clinical follow-up and treatment of patients and their families.
A study published in the Journal of the American Heart Association found that many adults with a history of cardiovascular disease continue to use tobacco products, despite being aware of the increased risk. The research revealed that only 2% of smokers with CVD quit using tobacco over a period of five years.
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Research suggests that mask-wearing, hand-washing, and physical distancing may reduce Kawasaki disease incidence in children. The study found a 40% decrease in cases after COVID-19 prevention efforts began in February 2020.
Only 5% of men and 9% of women meet daily fiber recommendations, associated with higher risks of heart disease and diabetes. Higher dietary fiber intake is strongly linked to reduced markers for heart and kidney disease in adults with diabetes.
A recent study published by the American Society for Nutrition compared the effects of low-fat and plant-centered diets on cardiovascular health. The research found that a plant-centered diet was associated with a lower long-term risk for cardiovascular disease, although both diets were linked with lower LDL levels.
A study of over 5.8 million children found that those whose mothers had high blood pressure or pre-eclampsia during pregnancy were more likely to develop stroke by age 41. The research suggests a potential long-term link between maternal hypertensive disorders and cardiovascular disease in offspring.
A new study published by the American Heart Association found that adults with OCD were more than three times as likely to experience an ischemic stroke, with the greatest risk among older adults. Researchers also discovered that medications used to treat OCD did not increase the risk of stroke.
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A nationwide study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a plant-based dinner can significantly reduce the risk of heart disease. The study, which analyzed data from over 27,000 U.S. adults, discovered that individuals who consumed more whole carbohydrates and unsaturated ...
Women who experience early menopause before age 40 have a 40% increased risk of developing coronary heart disease over their lifetime. The study suggests that clinicians should ask women about their menopause status earlier to optimize cardiovascular health and prevent heart disease.
A new study characterized heart disease and cerebrovascular deaths by race and ethnicity during the US COVID-19 pandemic, revealing that Black, Hispanic and Asian populations experienced significantly higher relative increases in heart disease deaths, with a 19% rise compared to non-Hispanic whites. The study suggests that disruptions ...
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A global commission led by Mount Sinai cardiologist Roxana Mehran recommends expanding education and health programs, research on women's heart disease, and prioritizing sex-specific interventions. The report aims to improve women's heart health outcomes worldwide by 2030.
The Lancet Commission report outlines 10 recommendations to improve health outcomes for millions of women worldwide and achieve the global targets set. The report aims to reduce the global burden of cardiovascular conditions in women, including heart disease and stroke, which account for 35% of deaths.
Researchers at Newcastle University discovered that tiny pieces of genetic material, miR-424-5p, increase in early stages of heart disease in type 1 diabetes patients. This biomarker has the potential to define additional therapeutic options to help patients with type 1 diabetes.
A University of Cincinnati researcher has found that plasma proteins discovered in the blood samples of diabetic patients who developed obstructive coronary disease may serve as biomarkers of severe heart blockage. This discovery could help patients with diabetes identify their risk and receive timely medical attention.
Research at Queen Mary University of London found that individuals with healthier hearts perform better in logic-based problems and have faster reaction times. Shared risk factors, such as diabetes and obesity, may also play a role in mediating interactions between heart and brain health.
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A new study has identified a link between a genetic variation called omentin and cardiometabolic health, specifically among Asian Indian participants. The researchers found that the role of adiponectin, an obesity-related biomarker, was linked to cardiovascular disease markers independent of common and central obesity.
Rheumatic heart disease (RHD) in Africa can be controlled through increased coverage of interventions like early detection and cardiac surgery, saving around 70,000 lives by 2030. The PEN-Plus package of integrated disease management offers a high return on investment.
Researchers developed the COVID Control app, which predicts COVID-19 outbreaks using user-reported symptoms and correlates with increased coronavirus prevalence in Baltimore City. The study showed that new loss of taste or smell was a strong predictor of confirmed cases, averaging five days before an outbreak.
A new AI-powered ECG screening tool detected asymptomatic low ejection fraction in patients with improved diagnosis rates. The study found that the AI intervention increased the diagnosis of low ejection fraction by 32% relative to usual care.
Research strongly links thin and brittle bones to increased heart attack and stroke risk in women. Thinning lower spine, top thigh bone, and hip were independently associated with a heightened risk, while osteoporosis was linked to a 79% higher cardiovascular disease risk.
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A study of over 5,000 couples found that individuals with a spouse who has heart disease are more than twice as likely to have heart disease themselves. Lifestyle factors such as physical activity, smoking, and alcohol use, as well as caregiver stress, were also identified as contributing to this increased risk.
A study found that sleeping six to seven hours a night is associated with more favorable heart health, while participants who slept less or more had higher cardiovascular risk scores. Inflammation levels, measured by C-reactive protein, were also higher in those with longer or shorter sleep durations.
A study found that Black women as young as their 20s and 30s show high rates of lifestyle-linked risk factors, including obesity and elevated blood pressure. The researchers call for preventive care and lifestyle changes among Black women under age 40 to mitigate the burden of heart disease.
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A new study finds that only half of adults with cardiovascular disease report getting a flu shot annually, highlighting the need for better vaccination efforts. Patients with certain conditions and those who attend college are more likely to receive a flu vaccine.
A recent study from Edith Cowan University found that consuming one cup of nitrate-rich leafy greens daily significantly reduces the risk of heart disease. The study, which examined data from over 50,000 people in Denmark, also revealed lower blood pressure and reduced risk of heart attacks, strokes, and heart failure.
Scientists developed a new mathematical model to predict disease onset risk using patient genomic data, providing improved predictive quality and personalized health risks for patients. The model can analyze large datasets of genetic markers linked to high blood pressure, heart disease, and type 2 diabetes.
An observational study of nearly 20,000 individuals found that greater intake of red and processed meat is associated with poorer heart function and stiffer arteries. In contrast, higher consumption of oily fish was linked to improved heart function and healthier arteries.
A randomized controlled study found that a Mediterranean diet combined with small portions of lean beef helped lower LDL cholesterol and non-HDL cholesterol levels. The study suggests that healthy diets can include a wide variety of foods, including red meat, while still being heart-friendly.
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The $1.5 million NIH grant will support four to six graduate students in cardometabolic disease research, enhancing their educational experience and providing more dollars for student stipends. This grant expands opportunities for minorities in AU's PhD programs, particularly those studying cardiometabolic diseases.
A study by Drexel University researchers found that job strain and social strain significantly increase women's risk of developing coronary heart disease. High-stress life events were also linked to an increased risk, with job strain contributing a 12% higher risk and social strain a 9% higher risk.
Researchers analyzed death records of over 22,000 Holocaust survivors and found a significant increase in cancer and heart disease mortality rates among women and men. The study supports theories that survivors experience general health resilience combined with vulnerabilities to specific diseases.
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New research from the University of East Anglia reveals comorbidities such as heart disease, respiratory disease, and obesity increase mortality rates in COVID-19 patients. Blood pressure medications found to be protective against severe outcomes.
A prospective cohort study found that patients who work more than 55 hours per week are at a twofold increased risk of having a second heart attack. Long working hours were associated with higher job strain and poorer lifestyle risk factors, particularly among men and younger workers.
Research estimates that physical inactivity is responsible for up to 8% of non-communicable diseases and deaths globally. The impact per person is greatest in high-income countries, while middle-income countries have the largest population affected by physical inactivity.
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A new study found that premature birth increases the risk of mortality in adulthood by up to 40% compared to full-term births. Chronic diseases such as heart disease and lung disease also pose a higher risk, with individuals born before 37 weeks having twice the risk of dying from these conditions.
Scientists have solved a fundamental mystery about how the heart works, revealing a new avenue for heart disease research. The discovery could lead to the development of new treatments for heart diseases, which are the leading cause of death worldwide.
A study of over 11,000 participants found that certain metabolic processes are associated with up to 14 diseases. The researchers identified key factors influencing human metabolism and developed a web application to make their results publicly available.
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Endogenous Cushing's syndrome is associated with a threefold increase in death, primarily due to cardiovascular disease and infections. The study analyzed data from over 19,000 patients and found that mortality rates were lower after 2000, but still unacceptably high.
A study finds Black women with PCOS have a poorer cardiometabolic risk profile than white women, including higher insulin levels, more insulin resistance, and increased blood pressure. The research highlights the need to address health disparities in women with PCOS, particularly among young Black women.
The European Society of Cardiology's ESC Preventive Cardiology 2021 conference explores the latest research and strategies for preventing heart disease. Experts discuss the role of diet, exercise, and lifestyle habits in maintaining cardiovascular health and identify the most effective ways to promote physical activity and healthy eating.
A new UCLA study finds that women with high muscle mass and high body fat have a greater degree of protection against heart disease-related death than those with low body fat. Meanwhile, men with high muscle mass and low body fat show a significant decrease in risk, but not as pronounced as seen in women.
Researchers found that traditional cardiovascular disease risk factors and elevated natriuretic peptide levels were associated with increased cancer risk. In contrast, participants with ideal cardiovascular health had a lower risk of future cancers.
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A study of 28 countries found men aged 50 and over had a 60% greater risk of death than women due to higher rates of smoking and heart disease. The gap varied across countries, highlighting the influence of social and cultural factors on health.
Researchers at Lund University developed a new examination method using NIRS and IVUS, which identifies high-risk plaques that cannot be seen with traditional angiograms. The study found that over 14% of treated patients experienced heart disease recurrence within four years, highlighting the importance of early detection and treatment.
Researchers have identified wild relatives of chickpea as a natural source of resistance to Ascochyta blight, a devastating disease that can cause up to 100% yield loss. These wild plants, including Cicer reticulatum and Cicer echinospermum, have been found to be resistant to the disease.
A study led by McMaster University found that consuming oily fish regularly reduces the risk of cardiovascular events like heart attacks and strokes by about a sixth in high-risk individuals. The critical ingredient is omega-3 fatty acids, which provide significant protection against cardiovascular disease.
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A new study aims to explore the cause and therapeutic treatment for left ventricular non-compaction cardiomyopathy (LVNC), also known as a 'spongy heart'. The research, led by University of Houston pharmacologist Mingfu Wu, seeks to determine how heart muscle fails to compact and develop medicines to reduce symptoms.
A large-scale study published in JAMA Cardiology found that inflammatory heart disease is rare among professional athletes with mild or asymptomatic COVID-19 infection. Only five out of 789 athletes developed heart inflammation, indicating a very low incidence of heart risk after mild COVID-19.
Among 789 professional athletes, imaging evidence of inflammatory heart disease was identified in five athletes (0.6%) who underwent cardiac screening and resumed play. No adverse cardiac events occurred in these athletes.
A study of hundreds of women found that accelerated abdominal fat gain during menopause is associated with increased heart disease risk, regardless of weight changes. Measuring waist circumference may be an early indicator of this risk beyond traditional BMI calculations.
A study published in EClinical Medicine found a correlation between retinal ischemic perivascular lesions and increased risk of cardiovascular disease. Researchers identified this mark in patients who underwent optical coherence tomography scans, suggesting it could serve as a biomarker for heart disease.
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A team of researchers has identified genes linked to both high body fat and protection from negative health impacts of obesity. The findings shed new light on the biology behind this disconnect, offering potential targets for therapies that lower diabetes and heart disease risk.
Emerging evidence suggests ketone bodies exert protective effects on patients with heart disease, potentially providing a safer alternative to the keto diet. Increasing circulating ketone levels through multiple mechanisms may offer therapeutic advantages in reducing cardiovascular risk factors.
A new study by Columbia University's Mailman School of Public Health found a strong association between jail incarceration and death rates from various causes in the US. The research estimated that every 1,000 population increase in local jail incarceration rate was associated with significant increases in mortality rates from infectio...
A decade after childbirth, women with a history of hypertensive disorders of pregnancy may experience changes in the structure and function of their hearts, predisposing them to ischemic heart disease and heart failure. Early therapeutic interventions can help prevent long-term cardiac complications.
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A recent study by University of Alberta cardiologists shows that patients with stable ischemic heart disease and high-risk cardiac anatomy benefit from revascularization with stents or bypass surgery. This approach leads to better health outcomes, including reduced risk of death or heart attack.
A genetic study found that heavy coffee consumption can increase lipid levels in the blood, heightening cardiovascular disease risk. Unfiltered brews like long blacks, espressos, and lattes contain a cholesterol-elevating compound called cafestol.
A new study published in eLife found that combining healthy lifestyle interventions with cholesterol-lowering medications yields the greatest benefits to heart health. Healthy lifestyles, including exercise and a balanced diet, can lower LDL cholesterol and increase HDL cholesterol, reducing the risk of heart disease.