Research on the causes and treatment of heart disease. Covers light exposure and heart health, sex differences, heart-in-a-dish models, and cardiac risk.
A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced various cardiovascular disease risks. The study also showed improvements in blood pressure, total cholesterol, and low-density lipoprotein levels.
A new study found that nearly 40% of Swedish adults aged 50-64 without known heart disease have some degree of atherosclerosis, according to researchers. This risk factor is often overlooked as having a zero calcification score, but can increase the likelihood of a heart attack, stroke or dying.
Researchers at Queen Mary University of London have created an experimental model of cardiomyopathy in inflammatory arthritis, replicating symptoms in RA patients. The study identifies a potential therapeutic approach to treat cardiomyopathy in RA patients.
A study published in Blood Advances found that hydroxyurea therapy can improve or even reverse cardiac complications in individuals living with sickle cell anemia. The longer duration of treatment was associated with better cardiac outcomes, suggesting the need for early screening and treatment initiation for this patient population.
A large-scale trial will assess the effects of cocoa supplements and multivitamins on aging, including inflammatory factors and genetic changes. Researchers aim to determine if cocoa consumption can reduce age-related health issues such as heart disease, stroke, and cancer.
A study published in Stroke Journal Report found that eating 4-5 peanuts per day lowers the risk of ischemic stroke and cardiovascular disease among Japanese men and women. Peanuts are rich in heart-healthy nutrients that help reduce cardiovascular disease risk factors.
A recent study published in the Journal of the American Heart Association found that people living with HIV are at a higher risk of sudden cardiac death compared to those without the virus. The study analyzed data from over 144,000 veterans and found that 26% of those who died from sudden cardiac death had HIV.
A recent study published by George Washington University researchers found that inclusionary zoning policies associated with lower rates of heart disease. The study also found that communities with such policies had fewer residents with high blood pressure and higher cholesterol.
Researchers found that remnant cholesterol levels above 24 micrograms per deciliter were associated with a 40-50% higher risk of major heart disease or stroke. The study suggests using remnant cholesterol as an additional metric for predicting cardiovascular disease and stroke risk, in addition to LDL cholesterol levels.
A recent study found that Cavalier King Charles spaniels have an increased number of disease-causing mutations compared to other breeds. The breed's history of intense breeding and limited gene pool has led to the accumulation of harmful genetic variants, including those linked to myxomatous mitral valve disease, a common heart condition.
Researchers discover that sudden cardiac episodes are caused by a combination of genetic mutations and chemical modifications in heart cells. The study uses new technology to manipulate the protein, demonstrating that phosphorylation can affect its function, particularly when paired with mutations.
Adults with heart disease living in rural areas experience higher levels of hopelessness and an increased risk of death. The study found that living in a rural setting is a significant risk factor for feelings of hopelessness among people with heart disease, which can more than triple the risk of death or heart attack.
A new project aims to create a cell atlas of the pediatric heart, filling the knowledge gap in molecular mechanisms involved in childhood death causes. Researchers will analyze healthy heart tissue from children using single-cell analysis and gene expression studies.
A comprehensive review reveals how excessive fructose intake can disrupt metabolic pathways, leading to diseases such as diabetes, fatty liver disease, and heart disease. The study highlights the role of protein transporters, gluconeogenesis, and gene-level changes in regulating fructose metabolism.
A two-year randomized controlled trial found that eating about ½ cup of walnuts daily modestly lowered LDL-cholesterol levels and reduced small LDL particles in healthy, older adults. The study suggests that walnuts can improve cardiovascular health by improving the quality of LDL particles.
The European Society of Cardiology has published new guidelines for the management of valvular heart disease. The guidelines recommend a comprehensive approach to diagnosis, including clinical examination and non-invasive evaluation using echocardiography, with treatment options such as medication, percutaneous or surgical valve replac...
Researchers have developed a dye-free method to visualize blood flow in the brain, allowing for detailed mapping of small capillaries and assessing blood flow rates. The technique has potential applications in understanding cardiovascular diseases, tumor growth, and targeted drug delivery.
Researchers at Masonic Medical Research Institute are using human induced pluripotent stem cells (hiPSCs) to create scientific models for studying cardiac arrhythmias and testing therapeutics. The integration of mathematical modeling tools enables the prediction of drug efficacy with minimal adverse effects.
Researchers identified distinct epigenetic patterns associated with heart disease in diverse populations, offering potential early warning signs. The study analyzed genome data from four cohorts and found unique methylation points linked to coronary heart disease.
The American Heart Association scientific statement highlights the importance of pre-test and post-test counseling for families with children undergoing CVD genetic testing. The statement emphasizes the need for a multidisciplinary approach to address family concerns and provide appropriate follow-up care.
Research found that longer and more frequent night shifts increase the risk of atrial fibrillation and coronary heart disease. Genetic predisposition did not affect the link between night shifts and AF risk.
Researchers at MUSC identify a type of fat called sphingolipid that could predict the severity of heart disease in African American patients with lupus. Higher levels of Lac-Cer are associated with increased disease activity and may have predictive value for patient progression.
A high-fat diet causes inflammation and damages intestinal epithelial cells, leading to the growth of harmful microbes and increased production of trimethylamine-N-oxide, a metabolite associated with cardiovascular disease. Researchers found that restoring intestinal function with a drug can blunt this effect.
The study, published in the Journal of the American Heart Association, found that subjective social status can be used to assess overall cardiovascular health in Hispanic/Latino adults. The researchers analyzed data from 15,374 participants and discovered a significant correlation between self-perceived social standing and cardiovascul...
Scientists discovered beige fat cells mediate subcutaneous fat's brain protection and provide anti-inflammatory effects. Beige fat transplantation restored cognitive function in obese mice with dementia-like behavior.
A large cross-sectional study in Canada found no association between loud noise exposure and changes in biomarkers for cardiovascular disease or outcomes. However, there were associations found between noise and several biomarkers, but these remained statistically insignificant after adjusting for important variables.
Researchers developed a new imaging technique that uses light and sound to detect plaques in arteries, potentially preventing strokes and heart attacks. The technique uses nanoparticles that absorb light and emit sound waves, allowing doctors to visualize the plaques in a non-invasive way.
Despite guidelines and legal requirements, women remain underrepresented in cardiovascular clinical trials, limiting treatment data on cardiovascular disease. Research shows that women respond differently to drugs than men, highlighting the need for sex-specific data in optimal care.
Research published in the BMJ Open journal suggests that middle-age height loss is associated with a heightened risk of early death from heart disease or stroke in Northern European women. Regular physical activity may help prevent height loss and lower cardiovascular disease risk, according to the findings.
Researchers found that a nutritionally rich, plant-centered diet is beneficial for cardiovascular health. A plant-centered diet is not necessarily vegetarian, and individuals can include animal products in moderation from time to time.
Researchers analyzed data from five large heart cohort studies to identify epigenetic changes associated with cardiovascular disease. The study found 33 common methylation sites linked to heart disease across diverse populations, providing a potential target for prevention and intervention.
A comprehensive review of keto diets found potential health risks, including increased heart disease risk, cancer risk, and adverse effects on pregnant women and kidney patients. For most people, the possible long-term benefits of a keto diet are outweighed by its potential drawbacks.
Researchers at Temple University are conducting a 5-year study to compare two approaches for reducing heart disease risk factors in Black birthing people. The study aims to eliminate disparities in heart disease among Black women and birthing people during and after pregnancy.
Researchers at Johns Hopkins Medicine found that hospitalized Black patients were diagnosed with aortic stenosis at half the rate of white patients, while Hispanic patients received treatment at a quarter of the rate. The study suggests racial differences may impact heart valve disease risk, highlighting the need for further exploration.
Researchers found that cardiometabolic abnormality, such as hypertension and high cholesterol, were more strongly associated with cognitive function and decline than obesity alone. Individuals with obesity and cardiometabolic abnormality had lower performance results on testing and greater cognitive decline.
A 20-year Mayo Clinic study suggests that allowing athletes with genetic heart diseases to return to play can be managed through a shared decision-making process. The study found no deaths related to sports and only minor cardiac events, showing that the risks can be minimized with proper testing, treatment, and safety measures.
A large systematic review and meta-analysis of statin use in healthy adults found a generally favorable benefit-to-harm balance. The study, published in the BMJ, suggests that the potential harms of statins are small and should not deter their use for primary prevention of cardiovascular disease.
Researchers found modest increases in heart attack hospitalization rates in younger women and men aged 15-34 years, with possible links to more sensitive diagnostic tests. Rates had declined since the 1980s but remain high, prompting continued surveillance and preventive strategies.
Research reveals South Asians have a significantly higher risk of developing heart disease compared to Europeans. Despite being under-represented in clinical estimators, South Asians experience a more than two-fold increased risk.
The UK HealthCare team has been awarded a prestigious CDC grant to optimize stroke prevention and care in Kentucky. The three-year grant will focus on implementing comprehensive stroke systems for those at high risk and stroke patients, with the goal of reducing mortality rates and addressing disparities.
Plant-based diets are recommended for healthy adults, with low consumption of salt and animal products, and increased intake of whole grains, fruits, vegetables, legumes, and nuts. Fermented dairy products like yogurt and cheese can also have a protective effect on cardiovascular health.
The European Society of Cardiology has announced the ESC Congress 2021 press programme, featuring live hot line sessions and embargoed press conferences. The programme will showcase new data on heart failure, valvular heart disease, cardiac arrest, hypertension, and atrial fibrillation.
Regularly consuming a Southern-style diet characterized by added fats, fried foods, eggs, organ meats, processed meats, and sugar-sweetened beverages may increase the risk of sudden cardiac death. In contrast, following a Mediterranean diet high in fruits, vegetables, fish, whole grains, and legumes can decrease this risk.
The American Heart Association has awarded a diversity grant supplement to the Masonic Medical Research Institute to investigate the connection between autism and heart disease. The grant will support Dr. Luana Nunes Santos' research on PTPN11 gene mutations and their effects on heart health.
Researchers found that a protein associated with reduced heart disease also protects against Alzheimer's-like brain damage in mice. Increasing levels of LDL receptor may slow or stop cognitive decline, offering a promising treatment strategy for dementia.
Researchers will examine regulation and disease relevance of alternative splicing in different types of heart cells. The project aims to map the path from splicing factor discovery to drug development.
Researchers found that mutations in cardiac myosin-binding protein C (cMyBP-C) cause HCM through unknown mechanisms, altering protein integrity or mechanical properties. This knowledge is crucial for clinical follow-up and treatment of patients and their families.
A study published in the Journal of the American Heart Association found that many adults with a history of cardiovascular disease continue to use tobacco products, despite being aware of the increased risk. The research revealed that only 2% of smokers with CVD quit using tobacco over a period of five years.
Research suggests that mask-wearing, hand-washing, and physical distancing may reduce Kawasaki disease incidence in children. The study found a 40% decrease in cases after COVID-19 prevention efforts began in February 2020.
Only 5% of men and 9% of women meet daily fiber recommendations, associated with higher risks of heart disease and diabetes. Higher dietary fiber intake is strongly linked to reduced markers for heart and kidney disease in adults with diabetes.
A recent study published by the American Society for Nutrition compared the effects of low-fat and plant-centered diets on cardiovascular health. The research found that a plant-centered diet was associated with a lower long-term risk for cardiovascular disease, although both diets were linked with lower LDL levels.
A study of over 5.8 million children found that those whose mothers had high blood pressure or pre-eclampsia during pregnancy were more likely to develop stroke by age 41. The research suggests a potential long-term link between maternal hypertensive disorders and cardiovascular disease in offspring.
A new study published by the American Heart Association found that adults with OCD were more than three times as likely to experience an ischemic stroke, with the greatest risk among older adults. Researchers also discovered that medications used to treat OCD did not increase the risk of stroke.
A nationwide study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a plant-based dinner can significantly reduce the risk of heart disease. The study, which analyzed data from over 27,000 U.S. adults, discovered that individuals who consumed more whole carbohydrates and unsaturated ...
Women who experience early menopause before age 40 have a 40% increased risk of developing coronary heart disease over their lifetime. The study suggests that clinicians should ask women about their menopause status earlier to optimize cardiovascular health and prevent heart disease.
A new study characterized heart disease and cerebrovascular deaths by race and ethnicity during the US COVID-19 pandemic, revealing that Black, Hispanic and Asian populations experienced significantly higher relative increases in heart disease deaths, with a 19% rise compared to non-Hispanic whites. The study suggests that disruptions ...
A global commission led by Mount Sinai cardiologist Roxana Mehran recommends expanding education and health programs, research on women's heart disease, and prioritizing sex-specific interventions. The report aims to improve women's heart health outcomes worldwide by 2030.
The Lancet Commission report outlines 10 recommendations to improve health outcomes for millions of women worldwide and achieve the global targets set. The report aims to reduce the global burden of cardiovascular conditions in women, including heart disease and stroke, which account for 35% of deaths.
Researchers at Newcastle University discovered that tiny pieces of genetic material, miR-424-5p, increase in early stages of heart disease in type 1 diabetes patients. This biomarker has the potential to define additional therapeutic options to help patients with type 1 diabetes.
A University of Cincinnati researcher has found that plasma proteins discovered in the blood samples of diabetic patients who developed obstructive coronary disease may serve as biomarkers of severe heart blockage. This discovery could help patients with diabetes identify their risk and receive timely medical attention.